A Combinatorial Code for Splicing Silencing: UAGG and GGGG Motifs

Open Access

Peer-reviewed

Research Article

Kyoungha Han ,

Contributed equally to this work with: Kyoungha Han, Gene Yeo

Current address: University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America

Affiliation Department of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
⨯
Gene Yeo ,

Contributed equally to this work with: Kyoungha Han, Gene Yeo

Current address: Crick-Jacobs Center for Computational and Theoretical Biology, Salk Institute, La Jolla, California, United States of America

Affiliation Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Boston, Massachusetts, United States of America
⨯
Ping An,

Affiliation Department of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
⨯
Christopher B Burge,

Affiliation Department of Biology, Massachusetts Institute of Technology, Boston, Massachusetts, United States of America
⨯
Paula J Grabowski

*To whom correspondence should be addressed. E-mail: pag4@pitt.edu

Affiliation Department of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
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Sequence motif analysis
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Introns
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Point mutation
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Plasmid construction
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Nucleotides
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Mutation
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RNA splicing
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Reverse transcriptase-polymerase chain reaction
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