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I am not able to agree with Dr. Daphne Atlas

Posted by caopeng on 24 Oct 2015 at 07:10 GMT

Dear Editor,

After reading Dr. Atlas's comment very carefully, I have to say that the claim is actually not correct. The main point of this article is that Synaptotagmin-1 and -7 are redundantly required for normal priming by calcium-independent mechanism. It is the calcium-independence and redundancy that is a conceptual advancement in this article.

It is quite surprising that the papers cited by Dr. Atlas in her comment are all about voltage-gated calcium channel and are only loosely related to synaptotagmin.

I would politely speculate that Dr. Atlas may have not read the article very carefully before posting her comment. And she made a typo with “Synaptotogamin".

Best,

Peng Cao

No competing interests declared.

Competing interest statement

caopeng replied to caopeng on 30 Oct 2015 at 09:20 GMT

Competing interest statement:
1. Dr. Peng Cao is not an author of the article.
2. Dr. Peng Cao is an independent investigator at Institute of Biophysics, Chinese Academy of Sciences.
3. Dr. Peng Cao has previously worked in Dr. Südhof's Laboratory.

No competing interests declared.