Reader Comments
Post a new comment on this article
Post Your Discussion Comment
Please follow our guidelines for comments and review our competing interests policy. Comments that do not conform to our guidelines will be promptly removed and the user account disabled. The following must be avoided:
- Remarks that could be interpreted as allegations of misconduct
- Unsupported assertions or statements
- Inflammatory or insulting language
Thank You!
Thank you for taking the time to flag this posting; we review flagged postings on a regular basis.
closeI am not able to agree with Dr. Daphne Atlas
Posted by caopeng on 24 Oct 2015 at 07:10 GMT
Dear Editor,
After reading Dr. Atlas's comment very carefully, I have to say that the claim is actually not correct. The main point of this article is that Synaptotagmin-1 and -7 are redundantly required for normal priming by calcium-independent mechanism. It is the calcium-independence and redundancy that is a conceptual advancement in this article.
It is quite surprising that the papers cited by Dr. Atlas in her comment are all about voltage-gated calcium channel and are only loosely related to synaptotagmin.
I would politely speculate that Dr. Atlas may have not read the article very carefully before posting her comment. And she made a typo with “Synaptotogamin".
Best,
Peng Cao
Competing interest statement
caopeng replied to caopeng on 30 Oct 2015 at 09:20 GMT
Competing interest statement:
1. Dr. Peng Cao is not an author of the article.
2. Dr. Peng Cao is an independent investigator at Institute of Biophysics, Chinese Academy of Sciences.
3. Dr. Peng Cao has previously worked in Dr. Südhof's Laboratory.