Single-cell analysis of the early Drosophila salivary gland reveals that morphogenetic control involves both the induction and exclusion of gene expression programs

Annabel May; Katja Röper

doi:10.1371/journal.pbio.3003133

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Peer-reviewed

Research Article

Single-cell analysis of the early Drosophila salivary gland reveals that morphogenetic control involves both the induction and exclusion of gene expression programs

Annabel May,

Roles Data curation, Formal analysis, Investigation, Methodology, Writing – original draft

Affiliation MRC Laboratory of Molecular Biology, Cambridge Biomedical Campus, Cambridge, United Kingdom
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Katja Röper

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Project administration, Visualization, Writing – original draft

* E-mail: kroeper@mrc-lmb.cam.ac.uk

Affiliation MRC Laboratory of Molecular Biology, Cambridge Biomedical Campus, Cambridge, United Kingdom

https://orcid.org/0000-0002-3361-766X

⨯

Single-cell analysis of the early Drosophila salivary gland reveals that morphogenetic control involves both the induction and exclusion of gene expression programs

Annabel May,
Katja Röper

Published: April 21, 2025
https://doi.org/10.1371/journal.pbio.3003133

About the Authors

Annabel May

Roles Data curation, Formal analysis, Investigation, Methodology, Writing – original draft

Affiliation MRC Laboratory of Molecular Biology, Cambridge Biomedical Campus, Cambridge, United Kingdom

Katja Röper

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Project administration, Visualization, Writing – original draft

* E-mail: kroeper@mrc-lmb.cam.ac.uk

Affiliation MRC Laboratory of Molecular Biology, Cambridge Biomedical Campus, Cambridge, United Kingdom

https://orcid.org/0000-0002-3361-766X

Competing Interests

The authors have declared that no competing interests exist.

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Salivary glands
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Salivary gland development
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Gene expression
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Marker genes
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Morphogenesis
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Tube morphogenesis
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In situ hybridization
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Transcription factors
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