About the Authors

Irene Fasciani

Contributed equally to this work with: Irene Fasciani, Francesco Petragnano

Roles Investigation, Methodology, Visualization

Affiliation Department of Biotechnological and Applied Clinical Sciences, University of L’Aquila, L’Aquila, Italy

Francesco Petragnano

Contributed equally to this work with: Irene Fasciani, Francesco Petragnano

Roles Data curation, Formal analysis, Investigation, Methodology, Visualization

Affiliation Department of Biotechnological and Applied Clinical Sciences, University of L’Aquila, L’Aquila, Italy

Ziming Wang

Roles Investigation

Affiliation Max Delbrück Center for Molecular Medicine, Berlin, Germany

Ruairidh Edwards

Roles Investigation

Affiliation Centre for Translational Pharmacology, Institute of Molecular, Cell and Systems Biology, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom

Narasimha Telugu

Roles Investigation, Methodology

Affiliation Max Delbrück Center for Molecular Medicine, Berlin, Germany

Ilaria Pietrantoni

Roles Data curation, Investigation, Visualization

Affiliation Department of Biotechnological and Applied Clinical Sciences, University of L’Aquila, L’Aquila, Italy

Ulrike Zabel

Roles Methodology, Resources

Affiliation Institute of Pharmacology and Toxicology, University of Würzburg, Würzburg, Germany

Henrik Zauber

Roles Investigation, Methodology

Affiliation Max Delbrück Center for Molecular Medicine, Berlin, Germany

Marlies Grieben

Roles Investigation, Methodology

Affiliation Max Delbrück Center for Molecular Medicine, Berlin, Germany

Maria E. Terzenidou

Roles Investigation

Affiliation Centre for Translational Pharmacology, Institute of Molecular, Cell and Systems Biology, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom

Jacopo Di Gregorio

Roles Investigation

Affiliation Department of Biotechnological and Applied Clinical Sciences, University of L’Aquila, L’Aquila, Italy

Cristina Pellegrini

Roles Investigation

Affiliation Department of Biotechnological and Applied Clinical Sciences, University of L’Aquila, L’Aquila, Italy

Silvano Santini Jr

Roles Investigation

Affiliation Department of Life, Health and Environmental Sciences, University of L’Aquila, L’Aquila, Italy

Anna R. Taddei

Roles Investigation

Affiliation Section of Electron Microscopy, Great Equipment Center, University of Tuscia, Viterbo, Italy

Bärbel Pohl

Roles Investigation, Methodology

Affiliation Max Delbrück Center for Molecular Medicine, Berlin, Germany

Stefano Aringhieri

Roles Investigation

Affiliation Department of Translational Research and New Technology in Medicine, University of Pisa, Pisa, Italy

Marco Carli

Roles Investigation

Affiliation Department of Translational Research and New Technology in Medicine, University of Pisa, Pisa, Italy

Gabriella Aloisi

Roles Investigation

Affiliation Department of Biotechnological and Applied Clinical Sciences, University of L’Aquila, L’Aquila, Italy

Francesco Marampon

Roles Writing – review & editing

Affiliation Department of Radiotherapy, University of Roma La Sapienza, Roma, Italy

Eve Charlesworth

Roles Investigation

Affiliation School of Physics and Astronomy, University of St Andrews, St Andrews, United Kingdom

Alexandra Roman

Roles Investigation

Affiliation Max Delbrück Center for Molecular Medicine, Berlin, Germany

Sebastian Diecke

Roles Supervision

Affiliation Max Delbrück Center for Molecular Medicine, Berlin, Germany

Vincenzo Flati

Roles Writing – review & editing

Affiliation Department of Biotechnological and Applied Clinical Sciences, University of L’Aquila, L’Aquila, Italy

Franco Giorgi

Roles Formal analysis, Supervision

Affiliation Department of Translational Research and New Technology in Medicine, University of Pisa, Pisa, Italy

Fernanda Amicarelli

Roles Supervision

Affiliation Department of Life, Health and Environmental Sciences, University of L’Aquila, L’Aquila, Italy

Andrew B. Tobin

Roles Supervision

Affiliation Centre for Translational Pharmacology, Institute of Molecular, Cell and Systems Biology, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom

Marco Scarselli

Roles Supervision, Writing – review & editing

Affiliation Department of Translational Research and New Technology in Medicine, University of Pisa, Pisa, Italy

Kostas Tokatlidis

Roles Formal analysis, Supervision, Writing – review & editing

Affiliation Centre for Translational Pharmacology, Institute of Molecular, Cell and Systems Biology, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom

Mario Rossi

Roles Formal analysis, Investigation, Writing – review & editing

Affiliation Department of Biotechnological and Applied Clinical Sciences, University of L’Aquila, L’Aquila, Italy

Martin J. Lohse

Roles Conceptualization, Formal analysis, Funding acquisition, Supervision, Writing – review & editing

martin.lohse@isarbioscience.de (MJL); pa53@st-andrews.ac.uk (PA); roberto.maggio@univaq.it (RM)

Affiliations Max Delbrück Center for Molecular Medicine, Berlin, Germany, Institute of Pharmacology and Toxicology, University of Würzburg, Würzburg, Germany, ISAR Bioscience Institute, Munich, Germany

Paolo Annibale

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Visualization, Writing – original draft, Writing – review & editing

martin.lohse@isarbioscience.de (MJL); pa53@st-andrews.ac.uk (PA); roberto.maggio@univaq.it (RM)

Affiliations Max Delbrück Center for Molecular Medicine, Berlin, Germany, School of Physics and Astronomy, University of St Andrews, St Andrews, United Kingdom

Roberto Maggio

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Visualization, Writing – original draft, Writing – review & editing

martin.lohse@isarbioscience.de (MJL); pa53@st-andrews.ac.uk (PA); roberto.maggio@univaq.it (RM)

Affiliation Department of Biotechnological and Applied Clinical Sciences, University of L’Aquila, L’Aquila, Italy

Competing Interests

The authors have declared that no competing interests exist.