About the Authors

Xuan Zhang

Contributed equally to this work with: Xuan Zhang, Tina Weiß, Mary Hongying Cheng, Siqi Chen

Roles Investigation, Writing – review & editing

Affiliation Department of Pharmacology and Chemical Biology, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

Tina Weiß

Contributed equally to this work with: Xuan Zhang, Tina Weiß, Mary Hongying Cheng, Siqi Chen

Roles Investigation, Writing – review & editing

Affiliation Institute of Biochemistry, Faculty of Life Sciences, Leipzig University, Leipzig, Germany

Mary Hongying Cheng

Contributed equally to this work with: Xuan Zhang, Tina Weiß, Mary Hongying Cheng, Siqi Chen

Roles Formal analysis, Investigation, Writing – review & editing

Affiliations Department of Computational and System Biology, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America, Laufer Center for Physical and Quantitative Biology, Stony Brook University, Stony Brook, New York, United States of America

Siqi Chen

Contributed equally to this work with: Xuan Zhang, Tina Weiß, Mary Hongying Cheng, Siqi Chen

Roles Investigation, Writing – review & editing

Affiliation Department of Immuno-Oncology, Beckman Research Institute, City of Hope Comprehensive Cancer Center, Duarte, California, United States of America

Carla Katharina Ambrosius

Roles Investigation

Affiliation Institute of Biochemistry, Faculty of Life Sciences, Leipzig University, Leipzig, Germany

Anne Sophie Czerniak

Roles Investigation

Affiliation Institute of Biochemistry, Faculty of Life Sciences, Leipzig University, Leipzig, Germany

Kunpeng Li

Roles Investigation

Affiliation Cryo-EM core facility, Case Western Reserve University, Cleveland, Ohio, United States of America

Mingye Feng

Roles Conceptualization, Funding acquisition, Investigation, Supervision, Writing – original draft, Writing – review & editing

mfeng@coh.org (MF); bahar@laufercenter.org (IB); abeck-sickinger@uni-leipzig.de (AGB-S); chengzh@pitt.edu (CZ)

Affiliation Department of Immuno-Oncology, Beckman Research Institute, City of Hope Comprehensive Cancer Center, Duarte, California, United States of America

Ivet Bahar

Roles Funding acquisition, Investigation, Supervision, Writing – original draft, Writing – review & editing

mfeng@coh.org (MF); bahar@laufercenter.org (IB); abeck-sickinger@uni-leipzig.de (AGB-S); chengzh@pitt.edu (CZ)

Affiliations Department of Computational and System Biology, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America, Laufer Center for Physical and Quantitative Biology, Stony Brook University, Stony Brook, New York, United States of America, Department of Biochemistry and Cell Biology, School of Medicine, Stony Brook University, Stony Brook, New York, United States of America

Annette G. Beck-Sickinger

Roles Conceptualization, Funding acquisition, Investigation, Supervision, Writing – original draft, Writing – review & editing

mfeng@coh.org (MF); bahar@laufercenter.org (IB); abeck-sickinger@uni-leipzig.de (AGB-S); chengzh@pitt.edu (CZ)

Affiliation Institute of Biochemistry, Faculty of Life Sciences, Leipzig University, Leipzig, Germany

Cheng Zhang

Roles Conceptualization, Funding acquisition, Investigation, Supervision, Writing – original draft, Writing – review & editing

mfeng@coh.org (MF); bahar@laufercenter.org (IB); abeck-sickinger@uni-leipzig.de (AGB-S); chengzh@pitt.edu (CZ)

Affiliation Department of Pharmacology and Chemical Biology, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

Competing Interests

The authors declare no competing financial interests.