About the Authors

Ruyuan Zhou

Contributed equally to this work with: Ruyuan Zhou, Qirou Wu

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation

Affiliations MOE Laboratory of Biosystems Homeostasis & Protection, Zhejiang Provincial Key Laboratory for Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, Hangzhou, China, Department of Hepatobiliary and Pancreatic Surgery and Zhejiang Provincial Key Laboratory of Pancreatic Disease, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China

Qirou Wu

Contributed equally to this work with: Ruyuan Zhou, Qirou Wu

Roles Data curation, Formal analysis, Investigation, Methodology

Affiliation MOE Laboratory of Biosystems Homeostasis & Protection, Zhejiang Provincial Key Laboratory for Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, Hangzhou, China

Mengqiu Wang

Roles Data curation, Formal analysis, Investigation

Affiliation MOE Laboratory of Biosystems Homeostasis & Protection, Zhejiang Provincial Key Laboratory for Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, Hangzhou, China

Seema Irani

Roles Data curation, Formal analysis, Investigation, Methodology

Affiliation Department of Molecular Biosciences; Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, Texas, United States of America

Xiao Li

Roles Investigation, Methodology

Affiliation MOE Laboratory of Biosystems Homeostasis & Protection, Zhejiang Provincial Key Laboratory for Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, Hangzhou, China

Qian Zhang

Roles Formal analysis, Funding acquisition, Investigation

Affiliations MOE Laboratory of Biosystems Homeostasis & Protection, Zhejiang Provincial Key Laboratory for Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, Hangzhou, China, Department of Hepatobiliary and Pancreatic Surgery and Zhejiang Provincial Key Laboratory of Pancreatic Disease, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China

Fansen Meng

Roles Investigation, Methodology

Affiliations MOE Laboratory of Biosystems Homeostasis & Protection, Zhejiang Provincial Key Laboratory for Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, Hangzhou, China, Department of Hepatobiliary and Pancreatic Surgery and Zhejiang Provincial Key Laboratory of Pancreatic Disease, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China

Shengduo Liu

Roles Investigation, Methodology

Affiliation MOE Laboratory of Biosystems Homeostasis & Protection, Zhejiang Provincial Key Laboratory for Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, Hangzhou, China

Fei Zhang

Roles Investigation, Methodology

Affiliation MOE Laboratory of Biosystems Homeostasis & Protection, Zhejiang Provincial Key Laboratory for Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, Hangzhou, China

Liming Wu

Roles Resources

Affiliation Department of Hepatobiliary and Pancreatic Surgery and Zhejiang Provincial Key Laboratory of Pancreatic Disease, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China

Xia Lin

Roles Resources

Affiliation Michael E. DeBakey Department of Surgery and Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas, United States of America

Xiaojian Wang

Roles Methodology, Resources

Affiliation Institute of Immunology, Zhejiang University School of Medicine, Hangzhou, China

Jian Zou

Roles Methodology, Resources

Affiliation Eye Center of the Second Affiliated Hospital School of Medicine, Institute of Translational Medicine, Zhejiang University, Hangzhou, China

Hai Song

Roles Methodology, Resources

Affiliation MOE Laboratory of Biosystems Homeostasis & Protection, Zhejiang Provincial Key Laboratory for Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, Hangzhou, China

Jun Qin

Roles Methodology, Resources

Affiliation CAS Key Laboratory of Tissue Microenvironment and Tumor, Center for Excellence in Molecular Cell Science, Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences, Shanghai, China

Tingbo Liang

Roles Resources

Affiliation Department of Hepatobiliary and Pancreatic Surgery and Zhejiang Provincial Key Laboratory of Pancreatic Disease, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China

Xin-Hua Feng

Roles Methodology, Resources, Writing – review & editing

Affiliations MOE Laboratory of Biosystems Homeostasis & Protection, Zhejiang Provincial Key Laboratory for Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, Hangzhou, China, Michael E. DeBakey Department of Surgery and Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas, United States of America

Yan Jessie Zhang

Roles Formal analysis, Investigation, Methodology

Affiliation Department of Molecular Biosciences; Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, Texas, United States of America

Pinglong Xu

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Supervision, Writing – original draft, Writing – review & editing

xupl@zju.edu.cn

Affiliations MOE Laboratory of Biosystems Homeostasis & Protection, Zhejiang Provincial Key Laboratory for Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, Hangzhou, China, Department of Hepatobiliary and Pancreatic Surgery and Zhejiang Provincial Key Laboratory of Pancreatic Disease, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China

Competing Interests

The authors have declared that no competing interests exist.