About the Authors

Daniel Stöppler

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

‡ These authors share first authorship on this work.

Affiliation Leibniz-Forschungsinstitut für Molekulare Pharmakologie, Berlin, Germany

Alex Macpherson

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

‡ These authors share first authorship on this work.

Affiliation UCB Celltech, Slough, United Kingdom

Susanne Smith-Penzel

Roles Data curation, Investigation, Methodology, Writing – review & editing

Affiliation Laboratory of Physical Chemistry, ETH Zürich, Zürich, Switzerland

Nicolas Basse

Roles Formal analysis, Investigation, Methodology, Project administration, Supervision, Writing – review & editing

Affiliation Sanofi, Strasbourg, France

Fabien Lecomte

Roles Investigation, Methodology, Writing – review & editing

Affiliation UCB Celltech, Slough, United Kingdom

Hervé Deboves

Roles Investigation, Methodology, Writing – review & editing

Affiliation Evotec, Milton, United Kingdom

Richard D. Taylor

Roles Investigation, Methodology, Writing – review & editing

Affiliation UCB Celltech, Slough, United Kingdom

Tim Norman

Roles Investigation, Methodology, Writing – review & editing

Affiliation UCB Celltech, Slough, United Kingdom

John Porter

Roles Investigation, Methodology, Writing – review & editing

Affiliation Midatech Pharma Plc, Milton, United Kingdom

Lorna C. Waters

Roles Formal analysis, Investigation, Methodology, Writing – review & editing

Affiliation Leicester Institute of Structural and Chemical Biology, University of Leicester, Leicester, United Kingdom

Marta Westwood

Roles Investigation, Methodology, Visualization, Writing – review & editing

Affiliation UCB Celltech, Slough, United Kingdom

Ben Cossins

Roles Investigation, Methodology, Writing – review & editing

Affiliation UCB Celltech, Slough, United Kingdom

Katharine Cain

Roles Investigation, Methodology, Writing – review & editing

Affiliation Vertex, Milton, United Kingdom

James White

Roles Investigation, Methodology, Writing – review & editing

Affiliation UCB Celltech, Slough, United Kingdom

Robert Griffin

Roles Investigation, Methodology, Writing – review & editing

Affiliation UCB Celltech, Slough, United Kingdom

Christine Prosser

Roles Investigation, Methodology, Writing – review & editing

Affiliation UCB Celltech, Slough, United Kingdom

Sebastian Kelm

Roles Investigation, Methodology, Writing – review & editing

Affiliation UCB Celltech, Slough, United Kingdom

Amy H. Sullivan

Roles Investigation, Methodology, Writing – review & editing

Affiliation Beryllium Discovery, Bedford, Massachusetts, United States of America

David Fox III

Roles Data curation, Formal analysis, Investigation, Methodology, Validation, Writing – review & editing

Affiliation Beryllium Discovery, Bedford, Massachusetts, United States of America

Mark D. Carr

Roles Formal analysis, Investigation, Methodology, Validation, Writing – review & editing

Affiliation Leicester Institute of Structural and Chemical Biology, University of Leicester, Leicester, United Kingdom

Alistair Henry

Roles Investigation, Methodology, Project administration, Supervision, Writing – review & editing

Affiliation UCB Celltech, Slough, United Kingdom

Richard Taylor

Roles Conceptualization, Investigation, Methodology, Project administration, Supervision, Writing – review & editing

Affiliation UCB Celltech, Slough, United Kingdom

Beat H. Meier

Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Supervision, Writing – review & editing

Affiliation Laboratory of Physical Chemistry, ETH Zürich, Zürich, Switzerland

Hartmut Oschkinat

Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Validation, Writing – review & editing

oschkinat@fmp-berlin.de (HO); alastair.lawson@ucb.com (ADL)

Affiliation Leibniz-Forschungsinstitut für Molekulare Pharmakologie, Berlin, Germany

Alastair D. Lawson

Roles Conceptualization, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Validation, Writing – review & editing

oschkinat@fmp-berlin.de (HO); alastair.lawson@ucb.com (ADL)

Affiliation UCB Celltech, Slough, United Kingdom

Competing Interests

I have read the journal’s policy and the authors of this manuscript have the following competing interests. Alex Macpherson, Fabien Lecomte, Richard D. Taylor, Tim Norman, Marta Westwood, Ben Cossins, James White, Robert Griffin, Christine Prosser, Sebastian Kelm, Alistair Henry, Richard Taylor, and Alastair D. Lawson are all current or former employees and/or shareholders in UCB Pharma. Nicolas Basse is an employee and/or shareholder in Sanofi. Hervé Deboves is an employee and/or shareholder in Evotec. John Porter is an employee and/or shareholder in Midatech Pharma. Katharine Cain is an employee and/or shareholder in Vertex. Amy H. Sullivan and David Fox III are/were employees and/or shareholders in Beryllium Discovery. This work was funded by UCB Pharma.