About the Authors

Carsten C. Scholz

carsten.scholz@uzh.ch

Affiliations Systems Biology Ireland, University College Dublin, Belfield, Dublin, Ireland, School of Medicine and Medical Science, University College Dublin, Belfield, Dublin, Ireland, The Conway Institute, University College Dublin, Belfield, Dublin, Ireland, Institute of Physiology and Zürich Center for Integrative Human Physiology (ZIHP), University of Zürich, Zürich, Switzerland

Javier Rodriguez

Affiliation Systems Biology Ireland, University College Dublin, Belfield, Dublin, Ireland

Christina Pickel

Affiliation Institute of Physiology and Zürich Center for Integrative Human Physiology (ZIHP), University of Zürich, Zürich, Switzerland

Stephen Burr

Affiliation Cambridge Institute for Medical Research, Department of Medicine, University of Cambridge, Cambridge Biomedical Research Centre, Cambridge, United Kingdom

Jacqueline-alba Fabrizio

Affiliation School of Biological Sciences, University of Adelaide, Adelaide, South Australia, Australia

Karen A. Nolan

Affiliation Institute of Physiology and Zürich Center for Integrative Human Physiology (ZIHP), University of Zürich, Zürich, Switzerland

Patrick Spielmann

Affiliation Institute of Physiology and Zürich Center for Integrative Human Physiology (ZIHP), University of Zürich, Zürich, Switzerland

Miguel A. S. Cavadas

Affiliations Systems Biology Ireland, University College Dublin, Belfield, Dublin, Ireland, The Conway Institute, University College Dublin, Belfield, Dublin, Ireland

Bianca Crifo

Affiliations School of Medicine and Medical Science, University College Dublin, Belfield, Dublin, Ireland, The Conway Institute, University College Dublin, Belfield, Dublin, Ireland

Doug N. Halligan

Affiliations School of Medicine and Medical Science, University College Dublin, Belfield, Dublin, Ireland, The Conway Institute, University College Dublin, Belfield, Dublin, Ireland

James A. Nathan

Affiliation Cambridge Institute for Medical Research, Department of Medicine, University of Cambridge, Cambridge Biomedical Research Centre, Cambridge, United Kingdom

Daniel J. Peet

Affiliation School of Biological Sciences, University of Adelaide, Adelaide, South Australia, Australia

Roland H. Wenger

Affiliation Institute of Physiology and Zürich Center for Integrative Human Physiology (ZIHP), University of Zürich, Zürich, Switzerland

Alex Von Kriegsheim

Affiliation Systems Biology Ireland, University College Dublin, Belfield, Dublin, Ireland

Eoin P. Cummins

Affiliations School of Medicine and Medical Science, University College Dublin, Belfield, Dublin, Ireland, The Conway Institute, University College Dublin, Belfield, Dublin, Ireland

Cormac T. Taylor

Affiliations Systems Biology Ireland, University College Dublin, Belfield, Dublin, Ireland, School of Medicine and Medical Science, University College Dublin, Belfield, Dublin, Ireland, The Conway Institute, University College Dublin, Belfield, Dublin, Ireland

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: CCS JR CP SB JaF KAN JAN DJP RHW AVK EPC CTT. Performed the experiments: CCS JR CP SB JaF KAN PS MASC BC DNH AVK. Analyzed the data: CCS JR CP SB JaF KAN JAN DJP RHW AVK EPC CTT. Contributed reagents/materials/analysis tools: CCS JR CP SB JaF JAN DJP RHW AVK EPC CTT. Wrote the paper: CCS CTT.