About the Authors

Jinlong Yin

Contributed equally to this work with: Jinlong Yin, Gunwoo Park

Affiliations Department of System Cancer Science, Graduate School of Cancer Science and Policy, National Cancer Center, Goyang, Korea, Specific Organs Cancer Branch, Research Institute and Hospital, National Cancer Center, Goyang, Korea

Gunwoo Park

Contributed equally to this work with: Jinlong Yin, Gunwoo Park

Affiliations Department of System Cancer Science, Graduate School of Cancer Science and Policy, National Cancer Center, Goyang, Korea, Specific Organs Cancer Branch, Research Institute and Hospital, National Cancer Center, Goyang, Korea

Tae Hoon Kim

Affiliation Specific Organs Cancer Branch, Research Institute and Hospital, National Cancer Center, Goyang, Korea

Jun Hee Hong

Affiliation Specific Organs Cancer Branch, Research Institute and Hospital, National Cancer Center, Goyang, Korea

Youn-Jae Kim

Affiliation Specific Organs Cancer Branch, Research Institute and Hospital, National Cancer Center, Goyang, Korea

Xiong Jin

Affiliation Department of Biotechnology, School of Life Sciences and Biotechnology, Korea University, Seoul, Korea

Sangjo Kang

Affiliation Specific Organs Cancer Branch, Research Institute and Hospital, National Cancer Center, Goyang, Korea

Ji-Eun Jung

Affiliations Specific Organs Cancer Branch, Research Institute and Hospital, National Cancer Center, Goyang, Korea, Department of Biotechnology, School of Life Sciences and Biotechnology, Korea University, Seoul, Korea

Jeong-Yub Kim

Affiliations Divisions of Radiation Cancer Research, Research Center for Radio-Senescence, Korea Institute of Radiological and Medical Sciences, Seoul, Korea, Department of Pathology, College of Medicine, Korea University, Seoul, Korea

Hyeongsun Yun

Affiliations Department of System Cancer Science, Graduate School of Cancer Science and Policy, National Cancer Center, Goyang, Korea, Specific Organs Cancer Branch, Research Institute and Hospital, National Cancer Center, Goyang, Korea

Jeong Eun Lee

Affiliations Department of System Cancer Science, Graduate School of Cancer Science and Policy, National Cancer Center, Goyang, Korea, Cancer Cell and Molecular Biology Branch, Research Institute and Hospital, National Cancer Center, Goyang, Korea

Minkyung Kim

Affiliation Department of System Cancer Science, Graduate School of Cancer Science and Policy, National Cancer Center, Goyang, Korea

Junho Chung

Affiliations Department of Biochemistry and Molecular Biology, Seoul National University, College of Medicine, Seoul, Korea, Department of Cancer Biology, Seoul National University College of Medicine, Seoul, Korea

Hyunggee Kim

Affiliation Department of Biotechnology, School of Life Sciences and Biotechnology, Korea University, Seoul, Korea

Ichiro Nakano

Affiliations Department of Neurological Surgery, The Ohio State University, Columbus, Ohio, United States of America, James Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio, United States of America

Ho-Shin Gwak

Affiliation Specific Organs Cancer Branch, Research Institute and Hospital, National Cancer Center, Goyang, Korea

Heon Yoo

Affiliations Department of System Cancer Science, Graduate School of Cancer Science and Policy, National Cancer Center, Goyang, Korea, Specific Organs Cancer Branch, Research Institute and Hospital, National Cancer Center, Goyang, Korea

Byong Chul Yoo

Affiliation Colorectal Cancer Branch, Research Institute and Hospital, National Cancer Center, Goyangi, Korea

Jong Heon Kim

Affiliations Department of System Cancer Science, Graduate School of Cancer Science and Policy, National Cancer Center, Goyang, Korea, Cancer Cell and Molecular Biology Branch, Research Institute and Hospital, National Cancer Center, Goyang, Korea

Eun-Mi Hur

Affiliations Center for Neuroscience, Brain Science Institute, Korea Institute of Science and Technology, Seoul, Korea, Department of Neuroscience, Korea University of Science and Technology, Daejeon, Korea

Jeongwu Lee

‡ JL is joint senior author on this work.

Affiliation Department of Stem Cell Biology and Regenerative Medicine, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, United States of America

Seung-Hoon Lee

nslsh@ncc.re.kr (SHL); mjpark@kcch.re.kr (MJP); jbp@ncc.re.kr (JBP)

Affiliations Department of System Cancer Science, Graduate School of Cancer Science and Policy, National Cancer Center, Goyang, Korea, Specific Organs Cancer Branch, Research Institute and Hospital, National Cancer Center, Goyang, Korea

Myung-Jin Park

nslsh@ncc.re.kr (SHL); mjpark@kcch.re.kr (MJP); jbp@ncc.re.kr (JBP)

Affiliation Divisions of Radiation Cancer Research, Research Center for Radio-Senescence, Korea Institute of Radiological and Medical Sciences, Seoul, Korea

Jong Bae Park

nslsh@ncc.re.kr (SHL); mjpark@kcch.re.kr (MJP); jbp@ncc.re.kr (JBP)

Affiliations Department of System Cancer Science, Graduate School of Cancer Science and Policy, National Cancer Center, Goyang, Korea, Specific Organs Cancer Branch, Research Institute and Hospital, National Cancer Center, Goyang, Korea

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JY GP JBP. Performed the experiments: JY GP THK JHH SK JEJ JYK HYu JEL MK BCY. Analyzed the data: JY GP JBP. Contributed reagents/materials/analysis tools: HSG HYo SHL HK IN MJP. Wrote the paper: JC JY GP EMH JHK JL SHL MJP JBP. Analysis of proteomics and bioinformatics: XJ YJK.