About the Authors

Ross A. Breckenridge

rbrecke@nimr.mrc.ac.uk

Affiliations Developmental Biology, MRC–National Institute for Medical Research, London, United Kingdom, Division of Medicine, University College London, London, United Kingdom

Izabela Piotrowska

Affiliation Developmental Biology, MRC–National Institute for Medical Research, London, United Kingdom

Keat-Eng Ng

Affiliation Developmental Biology, MRC–National Institute for Medical Research, London, United Kingdom

Timothy J. Ragan

Affiliation Division of Molecular Structure, MRC–National Institute for Medical Research, London, United Kingdom

James A. West

Affiliation Department of Biochemistry, Cambridge University, Cambridge, United Kingdom

Surendra Kotecha

Affiliation Developmental Biology, MRC–National Institute for Medical Research, London, United Kingdom

Norma Towers

Affiliation Developmental Biology, MRC–National Institute for Medical Research, London, United Kingdom

Michael Bennett

Affiliation Developmental Biology, MRC–National Institute for Medical Research, London, United Kingdom

Petra C. Kienesberger

Affiliation Cardiovascular Research Centre, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada

Ryszard T. Smolenski

Affiliation Department of Biochemistry, Medical University of Gdansk, Poland

Hillary K. Siddall

Affiliation Hatter Institute, Institute of Cardiovascular Sciences, University College London, London, United Kingdom

John L. Offer

Affiliation Physical Biochemistry, MRC–National Institute for Medical Research, London, United Kingdom

Mihaela M. Mocanu

Affiliation Hatter Institute, Institute of Cardiovascular Sciences, University College London, London, United Kingdom

Derek M. Yelon

Affiliation Hatter Institute, Institute of Cardiovascular Sciences, University College London, London, United Kingdom

Jason R. B. Dyck

Affiliation Cardiovascular Research Centre, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada

Jules L. Griffin

Affiliation Department of Biochemistry, Cambridge University, Cambridge, United Kingdom

Andrey Y. Abramov

Affiliation Institute of Neurology, University College London, London, United Kingdom

Alex P. Gould

Affiliation Division of Physiology and Metabolism, MRC–National Institute for Medical Research, London, United Kingdom

Timothy J. Mohun

Affiliation Developmental Biology, MRC–National Institute for Medical Research, London, United Kingdom

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

The author(s) have made the following declarations about their contributions: Conceived and designed the experiments: RB TM. Performed the experiments: RB IP KE TR JW SK NT MB PK RS HS. Analyzed the data: RB JO MM DY JD JG AA AG TM. Wrote the paper: RB AG TM.