About the Authors
- Jose Silva
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Contributed equally to this work with: Jose Silva, Ornella Barrandon
*To whom correspondence should be addressed. E-mail: jcs64@cscr.cam.ac.uk (JS); austin.smith@cscr.cam.ac.uk (AS)
Affiliations Wellcome Trust Centre for Stem Cell Research, University of Cambridge, Cambridge, United Kingdom , Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom
- Ornella Barrandon
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Contributed equally to this work with: Jose Silva, Ornella Barrandon
Affiliations Wellcome Trust Centre for Stem Cell Research, University of Cambridge, Cambridge, United Kingdom , Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom
- Jennifer Nichols
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Affiliations Wellcome Trust Centre for Stem Cell Research, University of Cambridge, Cambridge, United Kingdom , Department of Physiology, Development, and Neuroscience, University of Cambridge, Cambridge, United Kingdom
- Jitsutaro Kawaguchi
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Affiliations Wellcome Trust Centre for Stem Cell Research, University of Cambridge, Cambridge, United Kingdom , Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom
- Thorold W Theunissen
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Affiliations Wellcome Trust Centre for Stem Cell Research, University of Cambridge, Cambridge, United Kingdom , Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom
- Austin Smith
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*To whom correspondence should be addressed. E-mail: jcs64@cscr.cam.ac.uk (JS); austin.smith@cscr.cam.ac.uk (AS)
Affiliations Wellcome Trust Centre for Stem Cell Research, University of Cambridge, Cambridge, United Kingdom , Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom
Competing Interests
A patent application based on this work has been filed with the United Kingdom patent office by the University of Cambridge (inventors Jose Silva and Austin Smith).
Author Contributions
JS and OB contributed equally to the generation and experimental characterisation of iPS cells. JN produced chimaeras. JK performed Southern hybridisation. and TT performed real time RT-PCR measurements. AS and JS designed and supervised the study and wrote the paper.