About the Authors

Akiko Watanabe

Affiliation Laboratory for Molecular Psychiatry, RIKEN Brain Science Institute, Saitama, Japan

Tomoko Toyota

Affiliation Laboratory for Molecular Psychiatry, RIKEN Brain Science Institute, Saitama, Japan

Yuji Owada

Current address: Department of Organ Anatomy, Yamaguchi University Graduate School of Medicine, Yamaguchi, Japan

Affiliation Histology, Tohoku University Graduate School of Medicine, Miyagi, Japan

Takeshi Hayashi

Affiliation Animal Genome Research Unit, National Institute of Agrobiological Sciences, Ibaragi, Japan

Yoshimi Iwayama

Affiliation Laboratory for Molecular Psychiatry, RIKEN Brain Science Institute, Saitama, Japan

Miho Matsumata

Affiliation Division of Developmental Neuroscience, Center for Translational and Advanced Animal Research, Tohoku University Graduate School of Medicine, Miyagi, Japan

Yuichi Ishitsuka

Affiliation Laboratory for Molecular Psychiatry, RIKEN Brain Science Institute, Saitama, Japan

Akihiro Nakaya

Affiliation Department of Computational Biology, University of Tokyo, Tokyo, Japan

Motoko Maekawa

Current address: National Institute of Neuroscience, National Center for Neurology and Psychiatry, Tokyo, Japan

Affiliation Division of Developmental Neuroscience, Center for Translational and Advanced Animal Research, Tohoku University Graduate School of Medicine, Miyagi, Japan

Tetsuo Ohnishi

Affiliation Laboratory for Molecular Psychiatry, RIKEN Brain Science Institute, Saitama, Japan

Ryoichi Arai

Affiliation Department of Chemistry, Princeton University, Princeton, New Jersey, United States of America

Katsuyasu Sakurai

Affiliation Division of Developmental Neuroscience, Center for Translational and Advanced Animal Research, Tohoku University Graduate School of Medicine, Miyagi, Japan

Kazuo Yamada

Affiliation Laboratory for Molecular Psychiatry, RIKEN Brain Science Institute, Saitama, Japan

Hisatake Kondo

Affiliation Histology, Tohoku University Graduate School of Medicine, Miyagi, Japan

Kenji Hashimoto

Affiliation Division of Clinical Neuroscience, Chiba University Center for Forensic Mental Health, Chiba, Japan

Noriko Osumi

Affiliations Division of Developmental Neuroscience, Center for Translational and Advanced Animal Research, Tohoku University Graduate School of Medicine, Miyagi, Japan , CREST, Japan Science and Technology Agency (JST), Saitama, Japan

Takeo Yoshikawa

To whom correspondence should be addressed. E-mail: takeo@brain.riken.jp

Affiliations Laboratory for Molecular Psychiatry, RIKEN Brain Science Institute, Saitama, Japan , CREST, Japan Science and Technology Agency (JST), Saitama, Japan

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

A. Watanabe, N. Osumi, and T. Yoshikawa conceived and designed the project. A. Watanabe, T. Toyota, Y. Owada, Y. Iwayama, M. Matsumata, Y. Ishitsuka, M. Maekawa, K. Sakurai, Y. Owada, and K. Hashimoto performed the experiments. T. Hayashi, Y. Ishitsuka, and A. Nakaya performed QTL calculation. T. Hayashi also did statistical evaluation of effects of mouse strain and sex on PPI and its related measures, statistical analysis of complementation test, and wrote the corresponding parts of Results and Materials and Methods. Y. Owada and H. Kondo prepared Fabp7 knockout mice. A. Watanabe, T. Hayashi, Y. Iwayama, M. Matsumata, and K. Yamada analyzed the other data not described above. T. Toyota, K. Yamada, and T. Yoshikawa collected human DNA. R. Arai and T. Ohnishi examined the crystal structure of FABP7, and R. Arai wrote the description on the crystal structural analysis. N. Osumi wrote the description on neurogenesis, and T. Yoshikawa wrote the manuscript.