About the Authors

Oliver Medvedik

Contributed equally to this work with: Oliver Medvedik, Dudley W Lamming

Affiliation Paul F. Glenn Laboratories for the Biological Mechanisms of Aging, Department of Pathology, Harvard Medical School, Boston, Massachusetts, United States of America

Dudley W Lamming

Contributed equally to this work with: Oliver Medvedik, Dudley W Lamming

Affiliation Paul F. Glenn Laboratories for the Biological Mechanisms of Aging, Department of Pathology, Harvard Medical School, Boston, Massachusetts, United States of America

Keyman D Kim

Affiliation Paul F. Glenn Laboratories for the Biological Mechanisms of Aging, Department of Pathology, Harvard Medical School, Boston, Massachusetts, United States of America

David A Sinclair

To whom correspondence should be addressed. E-mail: david_sinclair@hms.harvard.edu

Affiliation Paul F. Glenn Laboratories for the Biological Mechanisms of Aging, Department of Pathology, Harvard Medical School, Boston, Massachusetts, United States of America

Competing Interests

DAS is a founder, director, share holder, and scientific consultant to Sirtris Pharmaceuticals, a company whose goal is to develop sirtuin-activating molecules to treat disease.

Author Contributions

OM, DWL, and DAS conceived and designed the experiments. OM, DWL, and KDK performed the experiments. All authors analyzed the data. OM, DWL, and DAS contributed reagents/materials/analysis tools and wrote the paper.