About the Authors

Matthew W Vaughn

Contributed equally to this work with: Matthew W Vaughn, Miloš Tanurdžić, Zachary Lippman

Affiliation Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, United States of America

Miloš Tanurdžić

Contributed equally to this work with: Matthew W Vaughn, Miloš Tanurdžić, Zachary Lippman

Affiliation Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, United States of America

Zachary Lippman

Contributed equally to this work with: Matthew W Vaughn, Miloš Tanurdžić, Zachary Lippman

Current address: Faculty of Agriculture, Hebrew University of Jerusalem, Rehovot, Israel

Affiliation Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, United States of America

Hongmei Jiang

Current address: Northwestern University, Evanston, Illinois, United States of America

Affiliation Department of Statistics, Purdue University, West Lafayette, Indiana, United States of America

Robert Carrasquillo

Current address: Harvard University, Cambridge, Massachusetts, United States of America

Affiliation Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, United States of America

Pablo D Rabinowicz

Current address: J. Craig Venter Institute, Rockville, Maryland, United States of America

Affiliation Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, United States of America

Neilay Dedhia

Affiliation Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, United States of America

W. Richard McCombie

Affiliation Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, United States of America

Nicolas Agier

Affiliation Unité de Recherche en Génomique Végétale, CNRS UMR8114, INRA UMR1165, Université d'Evry Val d'Essonne, Evry, France

Agnès Bulski

Affiliation Unité de Recherche en Génomique Végétale, CNRS UMR8114, INRA UMR1165, Université d'Evry Val d'Essonne, Evry, France

Vincent Colot

Affiliation Unité de Recherche en Génomique Végétale, CNRS UMR8114, INRA UMR1165, Université d'Evry Val d'Essonne, Evry, France

R.W Doerge

Affiliation Department of Statistics, Purdue University, West Lafayette, Indiana, United States of America

Robert A Martienssen

To whom correspondence should be addressed. E-mail: martiens@cshl.edu

Affiliation Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, United States of America

Competing Interests

RAM and WRM are founders of, and have interests in, Orion Genomics, a company that has licensed the methylation profiling technology described in this paper (United States 7,186,512).

Author Contributions

MWV, MT, ZL, and RAM conceived and designed the experiments. MWV, MT, ZL, and RC performed the experiments. MWV, MT, ZL, HJ, ND, WRM, NA, AB, VC, RWD, and RAM analyzed the data. MWV, HJ, PDR, ND, WRM, NA, AB, VC, and RWD contributed reagents/materials/analysis tools. MWV, MT, ZL, HJ, and RAM wrote the paper.