About the Authors

Laura A Bannister

Affiliations Department of Biomedical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York, United States of America , The Jackson Laboratory, Bar Harbor, Maine, United States of America

Roberto J Pezza

Affiliation Genetics and Biochemistry Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

Janet R Donaldson

Affiliation Genetics and Biochemistry Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

Dirk G de Rooij

Affiliations Department of Endocrinology, Utrecht University, Utrecht, The Netherlands , Department of Cell Biology, University Medical Center Utrecht, Utrecht, The Netherlands

Kerry J Schimenti

Affiliations Department of Biomedical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York, United States of America , The Jackson Laboratory, Bar Harbor, Maine, United States of America

R. Daniel Camerini-Otero

Affiliation Genetics and Biochemistry Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

John C Schimenti

To whom correspondence should be addressed. E-mail: jcs92@cornell.edu

Affiliations Department of Biomedical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York, United States of America , The Jackson Laboratory, Bar Harbor, Maine, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

LB and KS performed positional cloning of Mei11. All genetic, histological, cytological, and yeast two-hybrid data were collected and analyzed by LB and JCS, with histological staging expertise provided by DdR. In vitro biochemical experiments were designed and analyzed by RJP, JRD, and RDCO.