About the Authors

Xue-Ming Xu

Contributed equally to this work with: Xue-Ming Xu, Bradley A Carlson

Affiliation Molecular Biology of Selenium Section, Laboratory of Cancer Prevention, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America

Bradley A Carlson

Contributed equally to this work with: Xue-Ming Xu, Bradley A Carlson

Affiliation Molecular Biology of Selenium Section, Laboratory of Cancer Prevention, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America

Heiko Mix

Affiliation Department of Biochemistry, University of Nebraska, Lincoln, Nebraska, United States of America

Yan Zhang

Affiliation Department of Biochemistry, University of Nebraska, Lincoln, Nebraska, United States of America

Kazima Saira

Affiliation Department of Biochemistry, University of Nebraska, Lincoln, Nebraska, United States of America

Richard S Glass

Affiliation Department of Chemistry, The University of Arizona, Tucson, Arizona, United States of America

Marla J Berry

Affiliation Department of Cell and Molecular Biology, University of Hawaii at Manoa, Honolulu, Hawaii, United States of America

Vadim N Gladyshev

Affiliation Department of Biochemistry, University of Nebraska, Lincoln, Nebraska, United States of America

Dolph L Hatfield

To whom correspondence should be addressed. E-mail: hatfield@mail.nih.gov

Affiliation Molecular Biology of Selenium Section, Laboratory of Cancer Prevention, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

XMX, BAC, VNG, and DLH conceived and designed the experiments. XMX, BAC, YZ, and KS performed the experiments. XMX, BAC, HM, YZ, RSG, MJB, VNG, and DLH analyzed the data. XMX, BAC, RSG, MJB, VNG, and DLH wrote the paper.