The Impact of T Cell Intrinsic Antigen Adaptation on Peripheral Immune Tolerance

Nevil J Singh; Chuan Chen; Ronald H Schwartz

doi:10.1371/journal.pbio.0040340

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Open Access

Peer-reviewed

Research Article

The Impact of T Cell Intrinsic Antigen Adaptation on Peripheral Immune Tolerance

Nevil J Singh ,

*To whom correspondence should be addressed. E-mail: ns117r@nih.gov

Affiliation Laboratory of Cellular and Molecular Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Chuan Chen,

Affiliation Laboratory of Cellular and Molecular Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Ronald H Schwartz

Affiliation Laboratory of Cellular and Molecular Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
⨯

The Impact of T Cell Intrinsic Antigen Adaptation on Peripheral Immune Tolerance

Nevil J Singh,
Chuan Chen,
Ronald H Schwartz

Published: October 17, 2006
https://doi.org/10.1371/journal.pbio.0040340

About the Authors

Nevil J Singh

*To whom correspondence should be addressed. E-mail: ns117r@nih.gov

Affiliation Laboratory of Cellular and Molecular Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

Chuan Chen

Affiliation Laboratory of Cellular and Molecular Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

Ronald H Schwartz

Affiliation Laboratory of Cellular and Molecular Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

NJS and RHS conceived and designed the experiments. NJS and CC performed the experiments. NJS and CC analyzed the data. RHS contributed reagents/materials/analysis tools. NJS wrote the paper.

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T cells
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Genetically modified animals
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Host cells
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Cell differentiation
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Cytokines
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Mouse models
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Cytopathology
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