About the Authors

Adam Woolfe

Affiliation Medical Research Council Rosalind Franklin Centre for Genomics Research, Hinxton, Cambridge, United Kingdom

Martin Goodson

Affiliation Medical Research Council Rosalind Franklin Centre for Genomics Research, Hinxton, Cambridge, United Kingdom

Debbie K Goode

Affiliation Medical Research Council Rosalind Franklin Centre for Genomics Research, Hinxton, Cambridge, United Kingdom

Phil Snell

Affiliation Medical Research Council Rosalind Franklin Centre for Genomics Research, Hinxton, Cambridge, United Kingdom

Gayle K McEwen

Affiliation Medical Research Council Rosalind Franklin Centre for Genomics Research, Hinxton, Cambridge, United Kingdom

Tanya Vavouri

Affiliation Medical Research Council Rosalind Franklin Centre for Genomics Research, Hinxton, Cambridge, United Kingdom

Sarah F Smith

Affiliation Medical Research Council Rosalind Franklin Centre for Genomics Research, Hinxton, Cambridge, United Kingdom

Phil North

Affiliation Medical Research Council Rosalind Franklin Centre for Genomics Research, Hinxton, Cambridge, United Kingdom

Heather Callaway

Affiliation Medical Research Council Rosalind Franklin Centre for Genomics Research, Hinxton, Cambridge, United Kingdom

Krys Kelly

Affiliation Medical Research Council Rosalind Franklin Centre for Genomics Research, Hinxton, Cambridge, United Kingdom

Klaudia Walter

Affiliation Medical Research Council Biostatistics Unit, Institute of Public Health, Addenbrookes Hospital, Cambridge, United Kingdom

Irina Abnizova

Affiliation Medical Research Council Biostatistics Unit, Institute of Public Health, Addenbrookes Hospital, Cambridge, United Kingdom

Walter Gilks

Affiliation Medical Research Council Biostatistics Unit, Institute of Public Health, Addenbrookes Hospital, Cambridge, United Kingdom

Yvonne J. K Edwards

Affiliation Medical Research Council Rosalind Franklin Centre for Genomics Research, Hinxton, Cambridge, United Kingdom

Julie E Cooke

Affiliation Medical Research Council Rosalind Franklin Centre for Genomics Research, Hinxton, Cambridge, United Kingdom

Greg Elgar

To whom correspondence should be addressed. E-mail: gelgar@rfcgr.mrc.ac.uk

Affiliation Medical Research Council Rosalind Franklin Centre for Genomics Research, Hinxton, Cambridge, United Kingdom

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

MG and GE designed the study. AW, MG, DKG, PS, SFS, PN, and JEC performed the experiments. AW, MG, DKG, PS, GKM, TV, KK, JEC, and GE analysed the data. GKM, TV, HC, KW, IA, WG, and YJKE contributed reagents/materials/analysis tools. AW, GKM, JEC, and GE wrote the paper.