Cell-Passage Activity Is Required for the Malarial Parasite to Cross the Liver Sinusoidal Cell Layer

Tomoko Ishino; Kazuhiko Yano; Yasuo Chinzei; Masao Yuda

doi:10.1371/journal.pbio.0020004

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Open Access

Peer-reviewed

Research Article

Cell-Passage Activity Is Required for the Malarial Parasite to Cross the Liver Sinusoidal Cell Layer

Tomoko Ishino,

Affiliation Mie University School of Medicine, Mie, Japan
⨯
Kazuhiko Yano,

Affiliation Core Research for Evolutional Science and Technology (CREST), Japan Science and Technology Agency (JST), Kawaguchi, Saitama, Japan
⨯
Yasuo Chinzei,

Affiliations Mie University School of Medicine, Mie, Japan, Core Research for Evolutional Science and Technology (CREST), Japan Science and Technology Agency (JST), Kawaguchi, Saitama, Japan
⨯
Masao Yuda

*To whom correspondence should be addressed. E-mail: m-yuda@doc.medic.mie-u.ac.jp

Affiliations Mie University School of Medicine, Mie, Japan, Core Research for Evolutional Science and Technology (CREST), Japan Science and Technology Agency (JST), Kawaguchi, Saitama, Japan
⨯

Cell-Passage Activity Is Required for the Malarial Parasite to Cross the Liver Sinusoidal Cell Layer

Tomoko Ishino,
Kazuhiko Yano,
Yasuo Chinzei,
Masao Yuda

Published: January 20, 2004
https://doi.org/10.1371/journal.pbio.0020004

About the Authors

Tomoko Ishino

Affiliation Mie University School of Medicine, Mie, Japan

Kazuhiko Yano

Affiliation Core Research for Evolutional Science and Technology (CREST), Japan Science and Technology Agency (JST), Kawaguchi, Saitama, Japan

Yasuo Chinzei

Affiliations Mie University School of Medicine, Mie, Japan, Core Research for Evolutional Science and Technology (CREST), Japan Science and Technology Agency (JST), Kawaguchi, Saitama, Japan

Masao Yuda

*To whom correspondence should be addressed. E-mail: m-yuda@doc.medic.mie-u.ac.jp

Affiliations Mie University School of Medicine, Mie, Japan, Core Research for Evolutional Science and Technology (CREST), Japan Science and Technology Agency (JST), Kawaguchi, Saitama, Japan

Competing Interests

The authors have declared that no conflicts of interest exist.

Author Contributions

TI, YC, and MY conceived and designed the experiments. TI, KY, and MY performed the experiments. TI and MY analyzed the data. TI and MY wrote the paper.

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Sporozoites
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Single photon emission computed tomography
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Hepatocytes
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Parasitic diseases
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Kupffer cells
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Salivary glands
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Malarial parasites
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Cell motility
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