Advertisement

Browse Subject Areas

?

Click through the PLOS taxonomy to find articles in your field.

For more information about PLOS Subject Areas, click here.

Signaling molecules

Disruption of epidermal growth factor receptor signaling and cytoskeletal dynamics by mebendazole and gefitinib synergistically impairs paracrine cytokine signaling in non-small cell lung cancer and triple-negative breast cancer Cell lines

Mohamed El-Tanani, Shakta Mani Satyam, Syed Arman Rabbani, Yahia El-Tanani, Mark Sutherland, Frezah Muhana

published 16 Dec 2025

Loading metrics information...

Metrics unavailable. Please check back later.

Impact of substrate choice on human osteoclast differentiation and secretome: Implications for targeted therapeutic development

Fernanda D’Amélio, Hugo Vigerelli, Rodrigo Pinheiros Araldi, Adriana da Costa Neves, Álvaro Rossan de Brandão Prieto-da-Silva, Daniel Pimenta, Irina Kerkis

published 17 Oct 2025

Loading metrics information...

Metrics unavailable. Please check back later.

Mapping spatiotemporal distribution of forest carbon density in Xizang, China

Li Cheng, Zi ling Yang, Yang yang Xia, Wen wen Guo, Rui qiang Ren, Jiang ping Fang

published 25 Sep 2025

Loading metrics information...

Metrics unavailable. Please check back later.

3-O-acetylrubiarbonol B preferentially targets EGFR and MET over rubiarbonol B to inhibit NSCLC cell growth

A-Young Nam, Sang Hoon Joo, Na Yeong Lee, Goo Yoon, Jin Woo Park, MinKyun Na, Jung-Hyun Shim

published 08 Sep 2025

Loading metrics information...

Metrics unavailable. Please check back later.

Rabex-5 E3 and Rab5 GEF domains differ in their regulation of Ras, Notch, and PI3K signaling in Drosophila wing development

Theresa A. Reimels, Mia Steinberg, Hua Yan, Sivan Shahar, Ashley Rosenberg, Kristina Kalafsky, Max Luf, Lindsay Kelly, Stacia Octaviani, Cathie M. Pfleger

published 28 Oct 2024

Loading metrics information...

Metrics unavailable. Please check back later.

A comparative analysis of attitudes toward genome-edited food among Japanese public and scientific community

Ryuma Shineha, Kohei F. Takeda, Yube Yamaguchi, Nozomu Koizumi

published 16 Apr 2024

Loading metrics information...

Metrics unavailable. Please check back later.

Point mutations in Arf1 reveal cooperative effects of the N-terminal extension and myristate for GTPase-activating protein catalytic activity

Eric M. Rosenberg Jr., Xiaoying Jian, Olivier Soubias, Rebekah A. Jackson, Erin Gladu, Emily Andersen, Lothar Esser, Alexander J. Sodt, Di Xia, R. Andrew Byrd, Paul A. Randazzo

published 04 Apr 2024

Loading metrics information...

Metrics unavailable. Please check back later.

Clinical indicators combined with S100A12/TLR2 signaling molecules to establish a new scoring model for coronary artery lesions in Kawasaki disease

Yali Wu, Shasha Wang, Yang Zhou, Youjun Yang, Shiyu Li, Wei Yin, Yan Ding

published 12 Oct 2023

Loading metrics information...

Metrics unavailable. Please check back later.

Regulation of the two-pore domain potassium channel, THIK-1 and THIK-2, by G protein coupled receptors

Michihiro Tateyama, Yoshihiro Kubo

published 26 Apr 2023

Loading metrics information...

Metrics unavailable. Please check back later.

Obscurin Rho GEF domains are phosphorylated by MST-family kinases but do not exhibit nucleotide exchange factor activity towards Rho GTPases in vitro

Daniel Koch, Ay Lin Kho, Atsushi Fukuzawa, Alexander Alexandrovich, Kutti J. Vanaanen, Andrew Beavil, Mark Pfuhl, Martin Rees, Mathias Gautel

published 20 Apr 2023

Loading metrics information...

Metrics unavailable. Please check back later.

Clinical implication and potential function of ARHGEF6 in acute myeloid leukemia: An in vitro study

Kang Li, Haiquan Wang, Chaofan Yang, Chaojun Li, Bin Xue, Jiankui Zhou

published 07 Apr 2023

Loading metrics information...

Metrics unavailable. Please check back later.

Computational capabilities of a multicellular reservoir computing system

Vladimir Nikolić, Moriah Echlin, Boris Aguilar, Ilya Shmulevich

published 06 Apr 2023

Loading metrics information...

Metrics unavailable. Please check back later.

Unusual enantiomeric D,L-N-acyl homoserine lactones in Pectobacterium atrosepticum and Pseudomonas aeruginosa

Umang Dhaubhadel, Abiud E. Portillo, Ondřej Horáček, Yu-Sheng Sung, Daniel W. Armstrong

published 31 Mar 2023

Loading metrics information...

Metrics unavailable. Please check back later.

Advertisement

Create a weekly email alert for: Signaling molecules

You can change these options by clicking profile then "Alerts and Notifications"