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Signaling cascades

Dysregulated glucocorticoid-responsive immune genes in peripheral blood mononuclear cells as a shared molecular signature of autism spectrum disorder and irritable bowel syndrome

Kuo Zhang, Fangfang Mou, Jing Liu, Jianzhong Wang

published 09 Jul 2026

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Key targets and mechanisms by which gut microbiota-derived metabolites regulate Alzheimer’s disease through the immune - inflammatory pathway: Based on network pharmacology and molecular docking

Lei Miao, Fengwei Hou, Guanghong Li

published 06 Jul 2026

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Neuroprotective mechanisms of Thai traditional brain tonic Phy-Blica-O against LPS-induced neuroinflammation: Inhibition of NF-κB in microglia and mice

Thammarat Kaewmanee, Palanivel Ganesan, Piyapong Choochana, Pinanong Na-Phatthalung, Samuel Abiodun Kehinde, Sasitorn Chusri

published 26 Jun 2026

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In silico screening and molecular analyses identify apigenin from Scutellaria barbata as a potent AKT1 inhibitor in breast cancer

Md. Maruf Khan, Md. Arju Hossain, Fatematuz Zohora, Md. Sohel, Md. Faisal Amin, Fatematuz Zuhura Evamoni, M. Nazmul Hoque

published 25 Jun 2026

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Inhibition of SUR1-TRPM4 attenuates astrocyte swelling and reactivity under oxygen-glucose deprivation/reoxygenation

Yuanyuan Zhao, Narawut Pakaprot, Rujapope Sutiwisesak, Unchalee Vattarakorn, Sompol Tapechum

published 24 Jun 2026

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A novel m7G RNA methylation-related signature associated with MAPK signaling pathways in acute ischemic stroke

Wei-Gang Gong, Jian-Wei Lou, Sen Yin, Fang-Pu Yu, Wei Wu

published 23 Jun 2026

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Focus shifts in contextual and lexical cue interactions in GPT models

Wonil Chung, Keonwoo Koo

published 18 Jun 2026

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The mTOR/Akt pathway is involved in regulating astrocyte growth and GLT-1 expression during cerebral ischemia-reperfusion

Qiuling Li, Yiwen Yu, Huan Deng, Biao Li, Hao Zhao, Dong Lei, Mi Li, Shansha Xie, Jingmei Yu, Yuping Zhao, Shubin Yin, YiFei Ji

published 12 Jun 2026

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Repetitive hypoxic preconditioning protects retinal ganglion cells against damage caused by exposure to blast

Matthew M. Harper, Nickolas A. Boehme

published 08 Jun 2026

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Differential analysis of Short chain fatty acids incubation in autistic organoids based on transcriptome sequencing

Zaixin Wu, Xinyi Liu, Xiaobo Han, Miao Li

published 05 Jun 2026

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Transcriptomic profile of the hippocampus of rat strains with contrasting nervous system excitability

Marina Pavlova, Irina Shalaginova, Natalia Dyuzhikova

published 03 Jun 2026

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Unraveling dimethylformamide-induced neutrophilic differentiation in HL-60 cells: A proteomic and functional comparison with dimethyl sulfoxide

Othman Eldalal, Yasser Tabana, Dinesh Babu, Newton H. Tran, Steven Lockhart, Joshua Kranrod, John M. Seubert, Lusine Tonoyan, Richard P. Fahlman, Arno G. Siraki

published 13 May 2026

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Systematic identification of pan-cancer single-gene expression biomarkers in drug high-throughput screens

Ginte Kutkaite, Göksu Avar, Diyuan Lu, Thomas J. O’Neill, Daniel Krappmann, Michael P. Menden

published 11 May 2026

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