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Signaling cascades

Unraveling dimethylformamide-induced neutrophilic differentiation in HL-60 cells: A proteomic and functional comparison with dimethyl sulfoxide

Othman Eldalal, Yasser Tabana, Dinesh Babu, Newton H. Tran, Steven Lockhart, Joshua Kranrod, John M. Seubert, Lusine Tonoyan, Richard P. Fahlman, Arno G. Siraki

published 13 May 2026

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Systematic identification of pan-cancer single-gene expression biomarkers in drug high-throughput screens

Ginte Kutkaite, Göksu Avar, Diyuan Lu, Thomas J. O’Neill, Daniel Krappmann, Michael P. Menden

published 11 May 2026

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Ivermectin inhibits ER, HER2, and TGF-β pathways in ER-positive and endocrine-resistant breast cancer cells

Kitiya Rujimongkon, Patthamapon Adchariyasakulchai, Chanoknun Boonyaratsewee, Kantasorn Horpratraporn, Wannarasmi Ketchart

published 30 Apr 2026

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Single-cell RNA sequencing of healthy and diseased rat temporomandibular joint condyle cartilage

Sara Trbojevic, Xudong Dong, Robert Lafyatis, Michael S. Gold, Juan M. Taboas, Alejandro J. Almarza

published 30 Apr 2026

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Comparative Gene Co-expression Network Analysis of Proviral and Antiviral Responses to Dengue Virus-2 (DENV-2) and Zika Virus (ZIKV) Infection in Human Neural Progenitor Cells (hNPCs)

J. K. Owaresat, Diptta Dey, Md. Ahashan Habib Siam, Md. Ashraful Anam, AMAM Zonaed Siddiki

published 30 Apr 2026

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ATG7 vs. ATG5: Distinct autophagy pathways shaping TGF-β signaling and endothelial function

Aman Singh, Bharatsinai Peddi, Kriti S. Bhatt, Hien C. Nguyen, Krishna K. Singh

published 30 Apr 2026

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Targeting pancreatic cancer with combined inhibition of EGFR and RAF

Jakob Brandstetter, Lea Goldstein, Tim Schreiber, Rupert Palme, Tobias Lindner, Markus Joksch, Bernd Krause, Brigitte Vollmar, Simone Kumstel

published 24 Apr 2026

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Cadmium-induced DAG-PKC/IP₃-Ca²⁺ double signaling pathway and cell injury in gill of freshwater crabs Sinopotamon henanense

Jianxia Liu, Lijuan Yu, Jiachuan Yang, Rui Zhang, Jing Bai, Jinxiang Wang

published 22 Apr 2026

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Differential regulation of p62-ubiquitin conjugates in neurons versus astrocytes during cellular stress

David K. Sidibe, Erin M. Smith, Maeve L. Spivey, Maria C. Vogel, Sandra Maday

published 20 Apr 2026

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Sucralose inhibited cell survival through the activation of ER stress in human endothelial progenitor cells

Chia-Ying Li, Hung-Yu Lin, En-Pei Isabel Chiang, Hung-Chang Hung, Feng-Yao Tang

published 17 Apr 2026

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IGF1/IGF-1R promotes hepatocellular carcinoma progression by activating the Akt/GSK-3β pathway

Jiaojiao Liang, Xueyi Song, Yang Liu, Guoyu Yang, Bairu Zhu, Xiaolong Tang

published 09 Apr 2026

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Metformin attenuates TBHP-induced oxidative injury in human lens epithelial cells and is associated with SIRT1/FOXO1-related autophagy

Zhuxuan Yan, Wei Chi, Zhenguo Yan, Hanrui Wang

published 07 Apr 2026

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Association between chronic stress and the epigenome: Exploration of psychological and biological stress

Melissa Miller, Robin D. Brown, Cole Krautkramer, Rhea Gogia, Hagen Fritz, Dennis Wylie, Kerry Kinney, Frances A. Champagne

published 06 Apr 2026

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