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ERK signaling cascade

Wnt/β-catenin signalling modulates the timing of cell fate decision making in the early mouse embryo

Joaquin Lilao-Garzón, Elena Corujo-Simon, [ ... ], Silvia Muñoz-Descalzo

Development of a novel PIK3CA-mutated pancreatic tumor mouse model and evaluation of the therapeutic effects of a PI3K inhibitor

Yoshimasa Suzuki, Makoto Sugimori, [ ... ], Shin Maeda

5-O-Methylvisammioside inhibits HMGB1-induced Angiogenesis of hepatocellular carcinoma through RAGE/MEK/ERK signaling pathway

Wenyue Hou, Ting Zou, [ ... ], Lurong Zhang

Linsitinib inhibits IGF-1-induced cell proliferation and hyaluronic acid secretion by suppressing PI3K/Akt and ERK pathway in orbital fibroblasts from patients with thyroid-associated ophthalmopathy

Ji-Young Lee, Seong-Beom Lee, Suk-Woo Yang, Ji-Sun Paik

An in silico molecular docking and simulation study to identify potential anticancer phytochemicals targeting the RAS signaling pathway

Mahir Azmal, Jibon Kumar Paul, [ ... ], Ajit Ghosh

Exploiting mechanisms for hierarchical branching structure of lung airway

Hisako Takigawa-Imamura, Katsumi Fumoto, Hiroaki Takesue, Takashi Miura

Sustained intestinal epithelial monolayer wound closure after transient application of a FAK-activating small molecule

Sema Oncel, Qinggang Wang, [ ... ], Marc D. Basson

Activated Gab1 drives hepatocyte proliferation and anti-apoptosis in liver fibrosis via potential involvement of the HGF/c-Met signaling axis

Da-eun Nam, Soo-Jeung Park, [ ... ], Young S. Hahn

Xa inhibitor edoxaban ameliorates hepatic ischemia-reperfusion injury via PAR-2–ERK 1/2 pathway

Koki Maeda, Naohisa Kuriyama, [ ... ], Shugo Mizuno

Stellera chamaejasme L. extract inhibits adipocyte differentiation through activation of the extracellular signal-regulated kinase pathway

Jaegoo Yeon, Eunbin Kim, [ ... ], Jong Bae Seo

Regulation of gene expression downstream of a novel Fgf/Erk pathway during Xenopus development

Laura M. Cowell, Michael King, [ ... ], Harry V. Isaacs

Inhibition of ERK signaling for treatment of ERRα positive TNBC

David Musheyev, Esther Miller, [ ... ], Anya Alayev

Investigation of the anti-tumor mechanism of tirabrutinib, a highly selective Bruton’s tyrosine kinase inhibitor, by phosphoproteomics and transcriptomics

Ryohei Kozaki, Tomoko Yasuhiro, [ ... ], Takao Yoshida

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