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MAPK signaling cascades

Key targets and mechanisms by which gut microbiota-derived metabolites regulate Alzheimer’s disease through the immune - inflammatory pathway: Based on network pharmacology and molecular docking

Lei Miao, Fengwei Hou, Guanghong Li

Neuroprotective mechanisms of Thai traditional brain tonic Phy-Blica-O against LPS-induced neuroinflammation: Inhibition of NF-κB in microglia and mice

Thammarat Kaewmanee, Palanivel Ganesan, [ ... ], Sasitorn Chusri

In silico screening and molecular analyses identify apigenin from Scutellaria barbata as a potent AKT1 inhibitor in breast cancer

Md. Maruf Khan, Md. Arju Hossain, [ ... ], M. Nazmul Hoque

A novel m7G RNA methylation-related signature associated with MAPK signaling pathways in acute ischemic stroke

Wei-Gang Gong, Jian-Wei Lou, [ ... ], Wei Wu

Differential analysis of Short chain fatty acids incubation in autistic organoids based on transcriptome sequencing

Zaixin Wu, Xinyi Liu, Xiaobo Han, Miao Li

Transcriptomic profile of the hippocampus of rat strains with contrasting nervous system excitability

Marina Pavlova, Irina Shalaginova, Natalia Dyuzhikova

Unraveling dimethylformamide-induced neutrophilic differentiation in HL-60 cells: A proteomic and functional comparison with dimethyl sulfoxide

Othman Eldalal, Yasser Tabana, [ ... ], Arno G. Siraki

Systematic identification of pan-cancer single-gene expression biomarkers in drug high-throughput screens

Ginte Kutkaite, Göksu Avar, [ ... ], Michael P. Menden

IGF1/IGF-1R promotes hepatocellular carcinoma progression by activating the Akt/GSK-3β pathway

Jiaojiao Liang, Xueyi Song, [ ... ], Xiaolong Tang

Association between chronic stress and the epigenome: Exploration of psychological and biological stress

Melissa Miller, Robin D. Brown, [ ... ], Frances A. Champagne

Deciphering the synergistic mechanism of a novel flavonoid-antioxidant combination for asthma by combining systems pharmacology and experimental validation

Ziyi Chen, Xinling Ren, [ ... ], Wei Zhou

Systems biology analysis uncovers a ROS-associated gene signature and immunomodulatory role of CLEC4E in ischemic stroke

Lifang Yang, Tianyu Liang, Xiaodi Ding

Phosphorylations of serines 21/9 in glycogen synthase kinase 3α/β are dispensable for ^V600EBRAF-driven premalignant tumour development in the mouse intestine

Pooyeh Farahmand, Paulina Rzasa, [ ... ], Alessandro Rufini

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