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RNA structure

The structure of nontypeable Haemophilus influenzae SapA in a closed conformation reveals a constricted ligand-binding cavity and a novel RNA binding motif

Petra Lukacik, C. David Owen, Gemma Harris, Jani Reddy Bolla, Sarah Picaud, Irfan Alibay, Joanne E. Nettleship, Louise E. Bird, Raymond J. Owens, Philip C. Biggin, Panagis Filippakopoulos, Carol V. Robinson, Martin A. Walsh

published 15 Oct 2021

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U2 snRNA structure is influenced by SF3A and SF3B proteins but not by SF3B inhibitors

Veronica K. Urabe, Meredith Stevers, Arun K. Ghosh, Melissa S. Jurica

published 14 Oct 2021

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Thermal remodelling of Alternanthera mosaic virus virions and virus-like particles into protein spherical particles

Tatiana I. Manukhova, Ekaterina A. Evtushenko, Alexander L. Ksenofontov, Alexander M. Arutyunyan, Angelina O. Kovalenko, Nikolai A. Nikitin, Olga V. Karpova

published 28 Jul 2021

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Targeted capture sequencing identifies genetic variations of GRK4 and RDH8 in Han Chinese with essential hypertension in Xinjiang

Wenxi Jiang, Xizi Wang, Ronghui Li, Panpan Wang, Guangle Shan, Xiaodong Jia, Mingliang Gu

published 23 Jul 2021

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Dissection of a rice OsMac1 mRNA 5’ UTR to uncover regulatory elements that are responsible for its efficient translation

Hiromi Mutsuro-Aoki, Hiroshi Teramura, Ryoko Tamukai, Miho Fukui, Hiroaki Kusano, Mikhail Schepetilnikov, Lyubov A. Ryabova, Hiroaki Shimada

published 09 Jul 2021

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Predicting aptamer sequences that interact with target proteins using an aptamer-protein interaction classifier and a Monte Carlo tree search approach

Gwangho Lee, Gun Hyuk Jang, Ho Young Kang, Giltae Song

published 25 Jun 2021

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Potential G-quadruplexes and i-Motifs in the SARS-CoV-2

Efres Belmonte-Reche, Israel Serrano-Chacón, Carlos Gonzalez, Juan Gallo, Manuel Bañobre-López

published 08 Jun 2021

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Identification of 3’-UTR single nucleotide variants and prediction of select protein imbalance in mesial temporal lobe epilepsy patients

Tanusree Chaudhuri, Janaki Chintalapati, Madhusoodan Vijayacharya Hosur

published 04 Jun 2021

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Molecular dynamics analysis of N-acetyl-D-glucosamine against specific SARS-CoV-2’s pathogenicity factors

Ömür Baysal, Naeem Abdul Ghafoor, Ragıp Soner Silme, Alexander N. Ignatov, Volha Kniazeva

published 27 May 2021

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SARS-CoV-2: Possible recombination and emergence of potentially more virulent strains

Dania Haddad, Sumi Elsa John, Anwar Mohammad, Maha M. Hammad, Prashantha Hebbar, Arshad Channanath, Rasheeba Nizam, Sarah Al-Qabandi, Ashraf Al Madhoun, Abdullah Alshukry, Hamad Ali, Thangavel Alphonse Thanaraj, Fahd Al-Mulla

published 25 May 2021

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High-throughput screening of the ReFRAME, Pandemic Box, and COVID Box drug repurposing libraries against SARS-CoV-2 nsp15 endoribonuclease to identify small-molecule inhibitors of viral activity

Ryan Choi, Mowei Zhou, Roger Shek, Jesse W. Wilson, Logan Tillery, Justin K. Craig, Indraneel A. Salukhe, Sarah E. Hickson, Neeraj Kumar, Rhema M. James, Garry W. Buchko, Ruilian Wu, Sydney Huff, Tu-Trinh Nguyen, Brett L. Hurst, Sara Cherry, Lynn K. Barrett, Jennifer L. Hyde, Wesley C. Van Voorhis

published 22 Apr 2021

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Mapping of sequences in the 5’ region and 3’ UTR of tomato ringspot virus RNA2 that facilitate cap-independent translation of reporter transcripts in vitro

Dinesh Babu Paudel, Hélène Sanfaçon

published 09 Apr 2021

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A549 cells contain enlarged mitochondria with independently functional clustered mtDNA nucleoids

Aleksandrs Nasonovs, Miguel Garcia-Diaz, Daniel F. Bogenhagen

published 25 Mar 2021

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