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Ras signaling

Constitutive CCND1/CDK2 Activity Substitutes for p53 Loss, or MYC or Oncogenic RAS Expression in the Transformation of Human Mammary Epithelial Cells

Damian J. Junk, Rocky Cipriano, Martha Stampfer, Mark W. Jackson

Mutation in E1, the Ubiquitin Activating Enzyme, Reduces Drosophila Lifespan and Results in Motor Impairment

Hsiu-Yu Liu, Cathie M. Pfleger

Establishment of HRASG12V Transgenic Medaka as a Stable Tumor Model for In Vivo Screening of Anticancer Drugs

Yuriko Matsuzaki, Haru Hosokai, [ ... ], Hideyuki Saya

An Improved Ras Sensor for Highly Sensitive and Quantitative FRET-FLIM Imaging

Ana F. Oliveira, Ryohei Yasuda

RasGRP1, but Not RasGRP3, Is Required for Efficient Thymic β-Selection and ERK Activation Downstream of CXCR4

Dominic P. Golec, Nancy A. Dower, James C. Stone, Troy A. Baldwin

Ras/MAPK Signaling Modulates VEGFR-3 Expression through Ets-Mediated p300 Recruitment and Histone Acetylation on the Vegfr3 Gene in Lymphatic Endothelial Cells

Taeko Ichise, Nobuaki Yoshida, Hirotake Ichise

Synergistic Effects of Combined Wnt/KRAS Inhibition in Colorectal Cancer Cells

Luca Mologni, Stefania Brussolo, Monica Ceccon, Carlo Gambacorti-Passerini

Non Linear Programming (NLP) Formulation for Quantitative Modeling of Protein Signal Transduction Pathways

Alexander Mitsos, Ioannis N. Melas, [ ... ], Leonidas G. Alexopoulos

Loss of NF1 Expression in Human Endothelial Cells Promotes Autonomous Proliferation and Altered Vascular Morphogenesis

Anshika Bajaj, Qing-fen Li, Qingxia Zheng, Kevin Pumiglia

A New Dimension to Ras Function: A Novel Role for Nucleotide-Free Ras in Class II Phosphatidylinositol 3-Kinase Beta (PI3KC2β) Regulation

Katy A. Wong, Angela Russo, [ ... ], John P. O'Bryan

Genome-Wide Screening Reveals an EMT Molecular Network Mediated by Sonic Hedgehog-Gli1 Signaling in Pancreatic Cancer Cells

Xuanfu Xu, Yingqun Zhou, [ ... ], Chuanyong Guo

Overexpressed Galectin-3 in Pancreatic Cancer Induces Cell Proliferation and Invasion by Binding Ras and Activating Ras Signaling

Shumei Song, Baoan Ji, [ ... ], Robert S. Bresalier

Sensitization of Human Pancreatic Cancer Cells Harboring Mutated K-ras to Apoptosis

Ling Shen, Sung-Hoon Kim, Chang Yan Chen

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