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Molecular biology techniques

Single-cell RNA-seq and machine learning identify HMGN2 as a lactylation-associated hub gene in heart failure

Anzhen Xu, Yanbo Li, [ ... ], Qi Lu

Protodioscin mitigates cyclophosphamide-induced renal toxicity in HEK-293 cells by regulating endoplasmic reticulum stress, antioxidant defense, and apoptotic pathways

Ahmad Reza Ahmadi, Touraj Zamir Nasta, [ ... ], Cyrus Jalili

Serum Na-Cl value from routine blood tests reflects CO₂ retention in amyotrophic lateral sclerosis

Isamu Yamakawa, Ryota Tamura, [ ... ], Makoto Urushitani

A rapid and cost-effective Chelex-100 resin-based method for genomic DNA extraction from adult zebrafish tissues

Wei Feng, Boya Li, [ ... ], Xiandun Zhai

Insulin enhances RAGE ectodomain shedding by inducing Rab14-dependent ADAM10 cell surface trafficking in human aortic endothelial cells

Chung Hee Baek, Hyosang Kim, [ ... ], Won Seok Yang

Shotgun metagenomic profiling of the fecal microbiome in Lamp2 knockout mice reveals limited genotype-associated differences under standard housing

Maria Emfietzoglou, Maria Anna Bantounou, [ ... ], Demetrios G. Vavvas

Integrated analysis of transcriptomic and proteomic profiles identifies divergent regulatory networks for intramuscular fat in Chinese versus Western Pigs

Caoyan Xu, Pengcheng Shen, [ ... ], Chonglong Wang

Mitochondrial genome-derived microsatellites reveal genetic diversity and population structure in Callery pear populations

Alina Pokhrel, Denita Hadziabdic, [ ... ], Marcin Nowicki

Isoquercitrin ameliorates chondrocyte dysfunction in osteoarthritis by targeting AKT1-mediated mitochondrial dynamics regulation

Yuan Ding, Xiang Wang, [ ... ], Luyang Zhang

Epidemiology of human RSV in Taiwan, 2018–2024

Su-Lin Yang, Ming-Tsan Liu, [ ... ], Fang-Tzy Wu

A trainable language model with potential to modulate translation rates in non-model organisms by generating upstream untranslated region sequence libraries

Alexander D. Duggan, Matthew P. Newman, David R. McMillen

The changing landscape of Fabry disease: Impact of the inclusion of the GLA-gene in broader NGS or WES based panels on the phenotypic spectrum

Laura van Dussen, Emilie V. Albers, [ ... ], Mirjam Langeveld

Valuing education for limited-resource audiences using a willingness to accept experiment

Russell Tronstad, Ibrahima Sall

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