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Macromolecular structure analysis

A Consensus Method for the Prediction of ‘Aggregation-Prone’ Peptides in Globular Proteins

Antonios C. Tsolis, Nikos C. Papandreou, Vassiliki A. Iconomidou, Stavros J. Hamodrakas

A Locked Nucleic Acid Antisense Oligonucleotide (LNA) Silences PCSK9 and Enhances LDLR Expression In Vitro and In Vivo

Nidhi Gupta, Niels Fisker, [ ... ], Ellen Marie Straarup

Maltose-Binding Protein (MBP), a Secretion-Enhancing Tag for Mammalian Protein Expression Systems

Raphael Reuten, Denise Nikodemus, [ ... ], Manuel Koch

Comparative Bacterial Proteomics: Analysis of the Core Genome Concept

Stephen J. Callister, Lee Ann McCue, [ ... ], Mary S. Lipton

Clues to Neuro-Degeneration in Niemann-Pick Type C Disease from Global Gene Expression Profiling

Jonathan V. Reddy, Ian G. Ganley, Suzanne R. Pfeffer

Structure, Function, and Phylogeny of the Mating Locus in the Rhizopus oryzae Complex

Andrii P. Gryganskyi, Soo Chan Lee, [ ... ], Rytas Vilgalys

Evaluation of Digital PCR for Absolute RNA Quantification

Rebecca Sanders, Deborah J. Mason, Carole A. Foy, Jim F. Huggett

Metabolomics in Early Alzheimer's Disease: Identification of Altered Plasma Sphingolipidome Using Shotgun Lipidomics

Xianlin Han, Steve Rozen, [ ... ], Rima Kaddurah-Daouk

A Comprehensive Analysis of the Structure-Function Relationship in Proteins Based on Local Structure Similarity

Torgeir R. Hvidsten, Astrid Lægreid, [ ... ], Jan Komorowski

Divergent Effects of PERK and IRE1 Signaling on Cell Viability

Jonathan H. Lin, Han Li, [ ... ], Peter Walter

Quantifying Reproducibility in Computational Biology: The Case of the Tuberculosis Drugome

Daniel Garijo, Sarah Kinnings, [ ... ], Yolanda Gil

Structural insight into the role of novel SARS-CoV-2 E protein: A potential target for vaccine development and other therapeutic strategies

Manish Sarkar, Soham Saha

PFRED: A computational platform for siRNA and antisense oligonucleotides design

Simone Sciabola, Hualin Xi, [ ... ], Robert V. Stanton

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