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Macromolecular structure analysis

ProteoMapper: Alignment-aware identification and quantitative analysis of contextual motif–domain patterns in protein families

Sifullah Mahmud Sefa, Joyeeta Sarkar, Arif Hasan Khan Robin, Machbah Uddin

published 10 Aug 2026

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Monitoring radiation exposure through skin swab multi-omic profiling

Geraldine Vitry, Jerry Angdisen, Pauline Arriaga, Shawn Irgen-Gioro, Megan A. Sawant, Daniel C. Vuong, Peter Ilhardt, Jacques Fehr, Bartosz Cwikla, Brian Ponnaiya, Jamie L. Inman, Jian-Hua Mao, Antoine M. Snijders, Shazia Hamid, David Caballero-Lima, Guy Garty, Karyn Apfeldorf, Evagelia C. Laiakis

published 05 Aug 2026

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Spatially localized immune metaprograms reveal micro-niche organization in the human Dorsal Root Ganglion

Kyuhyung Choi, Kaehong Lee, Baeki E. Kang, Tae-Min Kim

published 03 Aug 2026

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Crystal structure of a closed ternary complex of a HNA Reverse Transcriptase in complex with a HNA/DNA duplex

Cédric Gutfreund, Mikhail Abramov, Frédérick Coosemans, Philipp Holliger, Piet Herdewijn, Karin Betz, Andreas Marx

published 31 Jul 2026

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Structural analysis of recombinant AAV vector genomes at single-molecule resolution

David Rouleau, Dimpal Lata, Serena Dollive, Robert E. Bruccoleri, Laura Van Lieshout, Diane Golebiowski, Ifeyinwa Iwuchukwu

published 30 Jul 2026

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Mapping the chaperonin TRiC/CCT interactome in mouse photoreceptors reveals functional significance for energy metabolism

Celine Brooks, David Salcedo-Tacuma, Isabella Mascari, Mark Eminhizer, Tuan Ngo, Douglas Kolson, Emily Sechrest, Tongju Guan, Neil Billington, Wen-Tao Deng, David Smith, Jianhai Du, Nikolai Skiba, Maxim Sokolov

published 29 Jul 2026

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Enhancing missense variant classification in predicted intrinsically disordered regions

Rohan D. Gnanaolivu, Steven N. Hart

published 27 Jul 2026

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Engineering of T7 DNA-dependent RNA polymerase with activity at elevated temperature

Svenja Hehn, Julia Gutbrod, Maxi Gutjahr, Andreas Marx

published 20 Jul 2026

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Epidemiological and genomic analysis of the dengue virus isolate from Jeddah, Saudi Arabia: Implications for future therapeutic development

Shymaa Damfo, Eitezaz Abdulshakoor Zaki, Mohammed Yahya Marouf, Mohammed Abdulmajeed Alghamdi, Khader Saleh Alghamdi, Bader Mohammed Alqarni, Mona A. Almusawi

published 16 Jul 2026

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Design and in silico validation of donor DNA for RNA-guided recombinase-mediated knockout of mstnb gene in Labeo rohita

Lukram Sushil Singh, Porkodi Murugesan, Gowhar Iqbal, Nagavara C. Nidarshan, Harini Gunasekaran, Ad. Viralkumar, Kiran D. Rasal, Manoj P. Brahmane, Sunil K. Nayak, Arvind A. Sonwane, Mukunda Goswami

published 15 Jul 2026

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Strategies for implementing genomic selection in a public soybean breeding program

Leonardo De Azevedo Peixoto, Eliana Monteverde Dominguez, Andrew Scaboo, Reka Howard, Asheesh K. Singh

published 13 Jul 2026

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GraphTransDTI: A novel hybrid framework combining graph transformer and CNN-BiLSTM for enhanced Drug-Protein Interaction prediction

Van-Vang Le, Mai Thi Anh Nhu, Pham Truong Viet Thong

published 10 Jul 2026

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Heptapharmacological activity of Quercetin-3-O-phosphate against lung cancer pathways

Maryam Abdulrahman Alahdal, Hadil Alahdal, Najat Binothman, Majidah Aljadani, Nawal Helmi, Maryam A. AL-Ghamdi, Alaa Hamed Habib, Misbahuddin Rafeeq, Tahani Bakhsh, Hadeel A. Alsufyani, Abeer Al Tuwaijri

published 10 Jul 2026

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