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Macromolecular engineering

Directed Chemical Evolution with an Outsized Genetic Code

Casey J. Krusemark, Nicolas P. Tilmans, Patrick O. Brown, Pehr B. Harbury

Genetically Engineered Yeast Expressing a Lytic Peptide from Bee Venom (Melittin) Kills Symbiotic Protozoa in the Gut of Formosan Subterranean Termites

Claudia Husseneder, Jennifer R. Donaldson, Lane D. Foil

Three Recombinant Engineered Antibodies against Recombinant Tags with High Affinity and Specificity

Hongyu Zhao, Ao Shen, Yang K. Xiang, David P. Corey

Reformatting Rituximab into Human IgG2 and IgG4 Isotypes Dramatically Improves Apoptosis Induction In Vitro

Jennifer D. Könitzer, Annette Sieron, Angelika Wacker, Barbara Enenkel

Directed Evolution and Resolution Mechanism of 1, 3-Propanediol Oxidoreductase from Klebsiella pneumoniae toward Higher Activity by Error-Prone PCR and Bioinformatics

Wei Jiang, Yuan Zhuang, Shizhen Wang, Baishan Fang

Engineering Proteins for Thermostability with iRDP Web Server

Priyabrata Panigrahi, Manas Sule, [ ... ], C. G. Suresh

A Web Resource for Standardized Benchmark Datasets, Metrics, and Rosetta Protocols for Macromolecular Modeling and Design

Shane Ó Conchúir, Kyle A. Barlow, [ ... ], Tanja Kortemme

Computational Design of the β-Sheet Surface of a Red Fluorescent Protein Allows Control of Protein Oligomerization

Timothy M. Wannier, Matthew M. Moore, Yun Mou, Stephen L. Mayo

In-Frame Amber Stop Codon Replacement Mutagenesis for the Directed Evolution of Proteins Containing Non-Canonical Amino Acids: Identification of Residues Open to Bio-Orthogonal Modification

James A. J. Arpino, Amy J. Baldwin, [ ... ], D. Dafydd Jones

Contribution of Disulfide Bridges to the Thermostability of a Type A Feruloyl Esterase from Aspergillus usamii

Xin Yin, Die Hu, [ ... ], Min-Chen Wu

Modeling Analysis of Signal Sensitivity and Specificity by Vibrio fischeri LuxR Variants

Deanna M. Colton, Eric V. Stabb, Stephen J. Hagen

Towards the Systematic Mapping and Engineering of the Protein Prenylation Machinery in Saccharomyces cerevisiae

Viktor Stein, Marta H. Kubala, [ ... ], Kirill Alexandrov

Desired Alteration of Protein Affinities: Competitive Selection of Protein Variants Using Yeast Signal Transduction Machinery

Misato Kaishima, Nobuo Fukuda, Jun Ishii, Akihiko Kondo

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