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Macromolecular engineering

Validating a Coarse-Grained Potential Energy Function through Protein Loop Modelling

James T. MacDonald, Lawrence A. Kelley, Paul S. Freemont

Engineered Monoclonal Antibody with Novel Antigen-Sweeping Activity In Vivo

Tomoyuki Igawa, Atsuhiko Maeda, [ ... ], Kunihiro Hattori

Engineering Agatoxin, a Cystine-Knot Peptide from Spider Venom, as a Molecular Probe for In Vivo Tumor Imaging

Sarah J. Moore, Cheuk Lun Leung, Heidi K. Norton, Jennifer R. Cochran

Selection of RNAs for Constructing “Lighting-UP” Biomolecular Switches in Response to Specific Small Molecules

Tamaki Endoh, Naoki Sugimoto

Identification and Multidimensional Optimization of an Asymmetric Bispecific IgG Antibody Mimicking the Function of Factor VIII Cofactor Activity

Zenjiro Sampei, Tomoyuki Igawa, [ ... ], Kunihiro Hattori

Probing the Effector and Suppressive Functions of Human T Cell Subsets Using Antigen-Specific Engineered T Cell Receptors

Qi Wan, Lina Kozhaya, [ ... ], Derya Unutmaz

Rational Engineering of a Human Anti-Dengue Antibody through Experimentally Validated Computational Docking

Luca Simonelli, Mattia Pedotti, [ ... ], Luca Varani

A Polypeptide-DNA Hybrid with Selective Linking Capability Applied to Single Molecule Nano-Mechanical Measurements Using Optical Tweezers

Fatemeh Moayed, Alireza Mashaghi, Sander J. Tans

Binding Pocket Optimization by Computational Protein Design

Christoph Malisi, Marcel Schumann, [ ... ], Birte Höcker

Deletional Protein Engineering Based on Stable Fold

Govindan Raghunathan, Nagasundarapandian Soundrarajan, [ ... ], Sun-Gu Lee

Programmable In Vivo Selection of Arbitrary DNA Sequences

Tuval Ben Yehezkel, Tamir Biezuner, [ ... ], Ehud Shapiro

Conjugation of Proteins by Installing BIO-Orthogonally Reactive Groups at Their N-Termini

Nagasundarapandian Soundrarajan, Sriram Sokalingam, [ ... ], Sun-Gu Lee

Targeting G with TAL Effectors: A Comparison of Activities of TALENs Constructed with NN and NK Repeat Variable Di-Residues

Michelle L. Christian, Zachary L. Demorest, [ ... ], Daniel F. Voytas

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