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Genetics

A computational Evo-Devo approach for elucidating the roles of PLETHORA transcription factors in regulating root development

Joel Rodríguez-Herrera, Kenia Aislinn Galván-Alcaraz, Ramsés Uriel Albarrán-Hernández, Juan Pablo Villa-Núñez, Gustavo Rodríguez-Alonso, Svetlana Shishkova

published 31 Jul 2025

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Epigenome and three-dimensional genome architecture remodeling during NDM29-mediated retro-transformation of neuroblastoma cells

Francesca Baldini, Aldo Pagano, Lama Zeaiter, Paolo Bianchini, Hawraa Zbeeb, Alberto Diaspro, Laura Vergani

published 31 Jul 2025

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Resveratrol aggravated H₂O₂-induced the HK-2 cell damage by inhibiting AKT phosphorylation

Shicheng Luo, Yuning Chen, Xuyi Ma, Feng Tian, Xiaozhou He

published 31 Jul 2025

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Decoding past microbial life and antibiotic resistance in İnonü Cave’s archaeological soil

Sukran Ozturk, F.Gülden Ekmen, Hamza Ekmen, Esra Mine Ünal, Ayşegül Er, Emre Keskin, Benjamin Stanley Arbuckle

published 31 Jul 2025

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Positional distribution of transcription factor binding sites in the human genome

Chun-Ping Yu, Zhi Thong Soh, Maloyjo Joyraj Bhattacharjee, Wen-Hsiung Li

published 30 Jul 2025

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Whole exome sequencing reveals pathogenic variants in CNGA3, CACNA1F, and RPGRIP1 in consanguineous Pakistani families with diverse retinal phenotypes

Jahangir Khan Tareen, Hamid Khan, Shamsul Ghani, Saeed Khan, Bakhtawar Khan, Yurong Wu, Muhammad Ajmal Khan, Syed Shahab Ud Din Shah, Abrar Hussain, Mubin Mustafa Kiyani, Shahid Bashir, Atta Ur Rehman, Muhammad Imran Shabbir, Hong-Tao Li

published 30 Jul 2025

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Role of rosuvastatin and pitavastatin in alleviating diabetic cardiomyopathy in rats: Targeting of RISK, NF-κB/ NLRP3 inflammasome and TLR4/ NF-κB signaling cascades

Dalia O. Saleh, Nesma M.E. Abo El Nasr, Marawan A. Elbaset, Marwa E. Shabana, Tuba Esatbeyoglu, Sherif M. Afifi, Ingy M. Hashad

published 30 Jul 2025

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How different cardioplegic solutions influence genes expression and cytokine response in an immature rat heart model of ischemia/reperfusion?

Arslan Mamedov, Dovydas Gečys, Povilas Jakuška, Rimantas Treinys, Deimantė Narauskaitė, Serik Aitaliyev, Eglė Rumbinaitė, Dainius Karčiauskas, Rimantas Benetis, Edgaras Stankevičius

published 29 Jul 2025

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Evaluation of the gastrotolerability of ketoprofen, lysine, and gabapentin co-crystal administration in an in vitro model of gastric epithelium: a proteomic update

Francesco D’Egidio, Laura Brandolini, Vanessa Castelli, Massimiliano Quintiliani, Andrea Aramini, Annamaria Cimini, Marcello Allegretti, Michele d’Angelo

published 29 Jul 2025

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Identification of differentially expressed genes associated with ferroptosis in ulcerative colitis

Fang Zhang, Xin Jiang, Xuyu Chen, Zheng Wang, Jianlei Xia, Bingcheng Wang, Mei Wang, Yanbing Ding

published 29 Jul 2025

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In vitro organ culture protocol for intact urogenital systems supporting gonadal differentiation

Sarah L. Whiteley, Clare E. Holleley, Arthur Georges

published 29 Jul 2025

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Analysis of metabolomics and transcriptomics data to assess interactions in microalgal co-culture of Skeletonema marinoi and Prymnesium parvum

Mahnoor Zulfiqar, Anne-Susann Abel, Emanuel Barth, Kristy Syhapanha, Remington Xavier Poulin, Sassrika Nethmini Costa Warnakulasuriya Dehiwalage, Georg Pohnert, Christoph Steinbeck, Kristian Peters, Maria Sorokina

published 28 Jul 2025

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In vitro and in vivo characterization of wild type BMP9 and a non-osteogenic variant in models of pulmonary arterial hypertension

Tobias G. Schips, Karl W. Kavalkovich, Lai-ming Yung, Salam Ibrahim, Makhosi Edmondson, Zhigang Hong, Chin-hu Huang, Simon Hinke, Xinkang Wang, Andrea R. Nawrocki, Annmarie Winkis, Jinquan Luo, Iman Farasat, Brian Geist, Yang Wang, Russell Bialecki, Jey R. Jeyaseelan, David R. Bauman

published 28 Jul 2025

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