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Gene expression

Integrative analysis reveals shared biomarkers and pathways in osteoporosis and rheumatoid arthritis using machine learning and single-cell sequencing

Jin Zhao, Yixuan Chen, [ ... ], Hongbo Yang

Explainable computational framework for subtype classification and biomarker identification in head and neck squamous cell carcinoma using machine learning

Anagha Rajan, Christopher Leela Biji, Mangalam Goutam Sinha, Iyappan Ramalakshmi Oviya

In vivo Nupr1 regulates oxidative stress–endoplasmic reticulum stress crosstalk and mitochondria-dependent apoptosis in varicocele-related testicular injury

Xue Jiang, Lemin Tang, [ ... ], Yaping Liao

Unveiling the neuroinflammatory potential of aspartame in Alzheimer’s disease: A comprehensive network toxicology and experimental validation approach

Dongyang Li, Xuejun Weng, [ ... ], Chunwei Wei

eNAMPT is a plasma biomarker of COVID-19 severity and ARDS progression linked to increased immune effector cell expression

Jason Canizales Galaviz, Amir Khan, [ ... ], Joe G. N. Garcia

Integrative network toxicology and machine learning reveal the potential role of 5-hydroxymethylfurfural in exacerbating pulmonary fibrosis

Qinghuan Yang, Fuli Li, Jiani Li, Ting Qin

A mucosal barrier injury related six gene transcriptomic signature associated with ulcerative colitis using machine learning and public transcriptomic data

Sen He, Pingliang Sun, Xiaoxin Duan

Comparative transcriptomic responses of tomato to Xanthomonas strains isolated from different hosts

Lorena Sánchez-Giménez, Eugenio Llorens, [ ... ], Gemma Camañes

Recurrent enhancer-promoter interactions across samples

Matthew Weston, Satvik Gunjala, Haiyan Hu, Xiaoman Li

Epigallocatechin-3-gallate attenuates PAR-2–mediated inflammatory signaling and preserves markers of mitochondrial integrity in osteoarthritic chondrocytes

Rajashree Patnaik, Yajnavalka Banerjee

Multi-dimensional structure and subtype-specific heterogeneity of angiogenesis in breast cancer

Dennis Baidoo

Loss of cohesin deacetylation through KDAC8 inactivation leads to altered cohesin complex expression and chromosomal instability

Tasha B. Toro, Razan H. Hammad, Thomas M. Huckaba, Terry J. Watt

Identification of prognostic biomarkers for nasopharyngeal carcinoma through microRNA‑mRNA network analysis combined with screening of immune‑related genes

Lihe He, Xuan Huang, Ping Huang

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