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Genetics

Prevalence and spectrum of germline BRCA1 and BRCA2 mutations in multiethnic cohort of breast cancer patients in Brunei Darussalam

Siti Nur Idayu Matusin, Nuramalina Mumin, Hazirah Zainal Abidin, Fatin Nurizzati Mohd Jaya, Zen Huat Lu, Mas Rina Wati Haji Abdul Hamid

published 18 Jun 2025

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Circulating exosome-circRNAs mediated downregulation of FGF9 through ceRNA mechanism aggravates renal fibrosis in diabetic nephropathy

Donglin Yang, Rongjiang Yin, Xiaomin Zhang, Xiaohui Wang, Xiaobin Pei, Zijie Guo, Pengyue Qiao, Kehan Zhu, Lin Wang, Pengchao Du

published 17 Jun 2025

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Integrated multi-omics analysis and predictive modeling of heart failure using sepsis-related gene signature

Yiping Lang, Tianyu Liang, Fei Li

published 17 Jun 2025

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Modulating autophagy in KRAS mutant colorectal cancer using combination of oncolytic reovirus and carbamazepine

Aaron Shaykevich, Danbee Chae, Isaac Silverman, Sanjay Goel, Radhashree Maitra

published 17 Jun 2025

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The effects of rifaximin and lactulose on the gut-liver-brain axis in rats with minimal hepatic encephalopathy

Xueyan Lin, Zhengchao Zhang, Yi Lin, Shiyun Lu, Rongrong Chen

published 17 Jun 2025

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Identification of Therapeutic Targets in Autism Spectrum Disorder through CHD8-Notch Pathway Interaction Analysis

Hewei Zhang, Shenghao Hua, Daiyan Jiao, Dong Chen, Qin Gu, Chao Bao

published 17 Jun 2025

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Global genetic diversity of Infectious Salmon Anemia Virus (ISAV) a scoping review protocol

Persia Carol Thapa, Ahsan Raquib, Kim Mears, Javier Sanchez, Sonja Saksida, Keith Larry Hammell, Krishna Kumar Thakur

published 17 Jun 2025

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EPHX1 and ERCC2 polymorphisms are associated with cisplatin-induced nephrotoxicity and prognosis in Thai cancer patients

Saad Ahmed, Jakris Eu-ahsunthornwattana, Thanaporn Thamrongjirapat, Aruchalean Taweewongsounton, Yutthana Rittavee, Nintita Sripaiboonkit Thokanit, Montien Ngodngamthaweesuk, Pitichote Hiranyatheb, Thanyanan Reungwetwattana, Nuttapong Ngamphaiboon, Natini Jinawath

published 17 Jun 2025

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Genetic diversity and phylogenetic relationships of Calotes and Uromastyx in the Cholistan Desert, Pakistan, based on COI gene analysis

Javed Hussain, Gulnaz Afzal, Muhammad Zeshan Haider, Iram Qadeer, Shazia Perveen, Hafiz Ishfaq Ahmad, Ahmed A. El-Mansi, Abdelalim A. Gadallah, Kasim Sakran Abass

published 17 Jun 2025

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Piriformospora indica culture filtrate and cell extract induce chicoric acid production in Echinacea purpurea hairy roots

Samane Khalili, Ahmad Moieni, Naser Safaie, Mohammad Sadegh Sabet

published 17 Jun 2025

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Identification and validation of differentially expressed genes in intramuscular fat metabolism in Guizhou yellow chickens using RNA-Seq analysis

Yingping Tian, Xiaoya Wang, Yongchao Rao, Xiaohong Zhou, Yaozhou Jiang, Qinsong Liu, Sheng Wu, Fuping Zhang

published 16 Jun 2025

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Metformin modulates the unfolded protein responses, altering lifespan and health-promoting effects in UPR-activated worms

Jerald Tan, Chutipong Chiamkunakorn, Kanpapat Boonchuay, Yiying Shi, Bart P. Braeckman, Wichit Suthammarak

published 16 Jun 2025

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TBpore cluster: A novel phylogenetic pipeline for tuberculosis transmission studies using nanopore next-generation sequencing data

Sophie Gagnon, Emmanuelle Ametepe, Floriane Point, William Cloutier Charette, Arpita Chakravarti, Paul Rivest, Pierre-Marie Akochy, Hafid Soualhine, Zamin Iqbal, Michael B. Hall, Simon Grandjean Lapierre

published 16 Jun 2025

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