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Genetics

Development of a prostate cancer biochemical recurrence risk signature using machine learning and motor protein-related genes

Weixing Wang, Guohai Xie, Zhonggao Wu

published 16 Sep 2025

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A single PCR-sequencing method to establish the frequency of kdr alleles in the stable fly, Stomoxys calcitrans: application to seven livestock farms from south of France

Mariana Ribeiro Sato, Géraldine Bossard, Guilhem Sempere, Philippe Jacquiet, Christelle Grisez, Geoffrey Gimonneau, Marc Desquesnes

published 16 Sep 2025

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Purinergic P2X receptor 7 (P2X7R) inhibition induced cytotoxicity in glioblastoma

Matthew Drill, Liyen Katrina Kan, Richard P. Sequeira, Padmakrishnan Chorakode Jayakrishnan, Martin Hunn, Nigel C. Jones, Terence J. O’Brien, Mastura Monif

published 16 Sep 2025

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Role of endothelial cell markers in prognosis of hepatocellular carcinoma: Integrating bioinformatics analysis and experimental validation

Zhaobin He, Jianqiang Cao, Yongzhe Yu, Cheng Peng

published 16 Sep 2025

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A phosphoramidate modification of FUDR, NUC-3373, causes DNA damage and DAMPs release from colorectal cancer cells, potentiating lymphocyte-induced cell death

Oliver J. Read, Jennifer Bré, Ying Zhang, Peter Mullen, Mustafa Elshani, David J. Harrison

published 16 Sep 2025

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Alternative splicing and residual function potentially expand the therapeutic landscape of the CFTRdele2ins182 variant

Cristina Pastorino, Ludovica Menta, Emanuela Pesce, Mariateresa Lena, Valeria Tomati, Valeria Capurro, Marco Di Duca, Vito Terlizzi, Andrea Gramegna, Francesco Blasi, Carlo Castellani, Serena Cappato, Federico Zara, Nicoletta Pedemonte, Renata Bocciardi

published 16 Sep 2025

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Optimized processing of Gardenia Fruits with ginger juice: Unveiling therapeutic mechanisms for cholestatic liver injury through TLR4/NF-κB, FXR/PPAR-α, and PI3K/AKT/GSK-3β

Chenzi Lyu, Xianglong Meng, Juan Wang, Haifeng Shao, Yang Wang, Yong-Ki Park, Shuosheng Zhang, Hyo Won Jung

published 16 Sep 2025

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Identifying novel genetic variants in epidermolysis Bullosa among Middle Eastern Arab Families: Insights from whole exome sequencing and computational analysis

Nancy Shehata, Babajan Banaganapalli, Hadiah Bassam Al Mahdi, Shmoukh Alghuraibi, Mahmoud Younis, Sultana Abdulghani, Noor Ahmad Shaik, Zuhier Awan, Fahad Hakami

published 16 Sep 2025

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Single-cell transcriptomic analysis reveals the association of Ccl6⁺Ccr2⁺Arg1⁺ macrophages with renal interstitial fibrosis in AKI

Xin Zheng, Jiayu Wang, Weinan Chen, Qingquan Xu, Tao Xu, Liang Chen

published 15 Sep 2025

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Genomic insights into Yanbian cattle: Breed-specific selective sweeps identified by whole-genome sequencing

Jihye Baek, Chun-Long Yan, Qingshan Gao, Seungwoo Son, Hak-kyo Lee, Donghyun Shin, Chang-Guo Yan

published 15 Sep 2025

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Microsatellite development for Theridion evexum (Araneae: Theridiidae) using low-coverage genome sequencing and the MiMi script

Ruth Madrigal-Brenes, Gilbert Barrantes, Luis Sandoval, Eric J. Fuchs

published 15 Sep 2025

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Construction and validation of a prognostic model based on mitochondria-associated endoplasmic reticulum membranes gene signature in LUAD patients

Qichen Zhang, Caihong Fu, Shasha Liu, Yue Leng, Ling Duan, Na Wang, Longxia Zhang, Hui Qiao

published 15 Sep 2025

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Gene profiles of peripheral white blood cells as potential predictors of pregnancy in embryo-recipient heifers

Mariam Raliou, Marie Margarete Meyerholz-Wohllebe, Doulaye Dembélé, Kirsten Mense, Maike Heppelmann, Christophe Richard, Pascale Chavatte-Palmer, Isabelle Dieuzy-Labaye, David Smith, Peter Zieger, Hans-Joachim Schuberth, Marion Schmicke, Iain Martin Sheldon, Olivier Sandra

published 15 Sep 2025

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