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Gene regulation

HDAC2 restrains IGF2BP1-associated m6A dysregulation in cervical cancer immunotherapy resistance

Qiuhong Deng, Zhi Wang, [ ... ], Yongmei Zhang

Systems pharmacology reveals type I interferon and myeloid-like B cell reprogramming as candidate druggable axes in antiphospholipid syndrome

Bin Sun, Yiqiao Lu, Wei Liu, Chengze Wang

An integrated systems biology and machine learning framework for identifying potential biomarkers and pathways in autism spectrum disorder

Sara Hosseinpoor, Hakimeh Zali, [ ... ], Abolhassan Ahmadiani

Mechanisms of transcutaneous bilateral auricular vagus nerve stimulation in treating functional dyspepsia through promoting M2 macrophage polarization

Daye Yang, Yiran Liu, [ ... ], Dan Wang

Putative anaerobic transformation pathway of microcystin-RR inferred from ¹⁵N labeling and multi-omics in an enriched shrimp pond sediment microbial community

Chuanyin Liu, Jingjing Zhang, [ ... ], Xinyu Wang

CASP1 as a key autophagy-related gene in atherosclerosis: Identification by bioinformatics analysis and experimental validation

Han Gao, Yuanling Guo, [ ... ], Weisong Liu

Transcriptome profile of delayed mortality in patients with invasive group A Streptococcal disease

Ville Kailankangas, Shintaro Katayama, [ ... ], Jaana Vuopio

Evaluation of extracellular microRNAs as potential biomarker candidates for assessing chlamydia reinfection risk

Chloe Meewes Lewis, Kanupriya Gupta, [ ... ], William M. Geisler

Genome-wide identification of tomato B-RRs gene family and expression analysis in response to ABA and drought

Meihua Sun, Jing Li, [ ... ], Leiping Hou

Environmental enrichment attenuates chronic stress–induced disruptions in the gut microbiota, intestinal barrier, and brain

Seung Ju Kang, Hyeong Ju Nam, Min Kyung Song

Prediction of potential biomarkers and therapeutic targets in HIV viremic patients using immune-related circRNA-miRNA-mRNA regulatory networks

Negin Faraji, Leila Rouhi, [ ... ], Ladan Abbasian

A chemically optimized, GalNAc-conjugated siRNA targeting HSD17B13 demonstrates efficacy in a human 3D organoid model of MASH, showcasing an alternative to animal testing

Qin Meng, Xujia Wang, [ ... ], Mu Wang

Genetically predicted triglyceride levels and endometriosis risk: Mendelian randomization with exploratory multi-omics analyses

Yonghong Li, Jianan He, [ ... ], Mengsha Qi

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