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Gene regulation

Genome-wide identification of tomato B-RRs gene family and expression analysis in response to ABA and drought

Meihua Sun, Jing Li, Yaofeng Zhang, Linlin Tian, Yanxiu Miao, Longqiang Bai, Leiping Hou

published 17 Aug 2026

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Environmental enrichment attenuates chronic stress–induced disruptions in the gut microbiota, intestinal barrier, and brain

Seung Ju Kang, Hyeong Ju Nam, Min Kyung Song

published 14 Aug 2026

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Prediction of potential biomarkers and therapeutic targets in HIV viremic patients using immune-related circRNA-miRNA-mRNA regulatory networks

Negin Faraji, Leila Rouhi, Azam Bolhassani, Behnam Hasannejad-asl, Kazem Baesi, Ladan Abbasian

published 14 Aug 2026

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A chemically optimized, GalNAc-conjugated siRNA targeting HSD17B13 demonstrates efficacy in a human 3D organoid model of MASH, showcasing an alternative to animal testing

Qin Meng, Xujia Wang, Yuxuan Zhang, Sudeep Pushpakom, Jun Yang, Hui Feng, Mu Wang

published 14 Aug 2026

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Genetically predicted triglyceride levels and endometriosis risk: Mendelian randomization with exploratory multi-omics analyses

Yonghong Li, Jianan He, Yuanqing Zhang, Min Yang, Zhimao Jia, Yidan Fan, Shuyun Liu, Mengsha Qi

published 13 Aug 2026

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L-Phenylalanine restriction enhances L-boronophenylalanine uptake and improves boron neutron capture therapy efficacy in tumor cell lines

Yuki Tamari, Rie Saba, Takushi Takata, Hiroyuki Kimura, Mao Takita, Kenta Yashiro, Minoru Suzuki, Hideya Yamazaki, Kei Yamada

published 13 Aug 2026

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Network pharmacology and molecular simulation study on the multi-target gene regulatory mechanism of Isatis indigotica against hepatic inflammation

XueRu Li, Yang Wang, HuiJun Cheng, Rong Chen, XiaoLu Chen

published 13 Aug 2026

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Unraveling the molecular Nexus of Alzheimer’s Disease and HIV encephalitis: The role of cellular senescence and transcriptional regulation

Hao Zhang, WenJun Chen, ShuYou Yuan, ShaoXiang Ding, HongXia Bao, Bo Cai, JunKai Sun, Wei Lu, HaoGang Zhu, GuoXun Shi

published 13 Aug 2026

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Ortholog transfer stress test: Regulatory edge conservation across species, tissues, and evolutionary distance

Ihor Kendiukhov

published 12 Aug 2026

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Analyzing an organism’s sensors using Maximum Entropy (MaxEnt) models with bias, variance, and confusion matrices

Christopher Wang, Elianna Schimke, Tristan Kako, Aiden Gao, Martina Lamberti, Joost le Feber, Sarah Marzen

published 11 Aug 2026

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ProteoMapper: Alignment-aware identification and quantitative analysis of contextual motif–domain patterns in protein families

Sifullah Mahmud Sefa, Joyeeta Sarkar, Arif Hasan Khan Robin, Machbah Uddin

published 10 Aug 2026

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Dual regulatory mechanisms of YGP1 expression in response to glucose availability in Saccharomyces cerevisiae

Megumi Sato, Kaoru Irie, Yasuyuki Suda, Tomoaki Mizuno, Kenji Irie

published 07 Aug 2026

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Induction of osteogenic differentiation of MSCs by GSK3β knockdown through GSK3β siRNAs transfection

Elena V. Galitsyna, Anastasiia A. Buianova, Tatiana B. Bukharova, Irina A. Krivosheeva, Mikhail Yu. Skoblov, Dmitriy V. Goldshtein

published 07 Aug 2026

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