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DNA cleavage

Analyzing dwell times with the Generalized Method of Moments

Sadie Piatt, Allen C. Price

A study on endonuclease BspD6I and its stimulus-responsive switching by modified oligonucleotides

Liudmila A. Abrosimova, Anzhela Yu. Migur, [ ... ], Tatiana S. Oretskaya

Pre-existing technological core and roots for the CRISPR breakthrough

Christopher L. Magee, Patrick W. Kleyn, [ ... ], Subarna Basnet

Novel isothiacalothrixin B analogues exhibit cytotoxic activity on human colon cancer cells in vitro by inducing irreversible DNA damage

Nachiappan Dhatchana Moorthy, Bose Muthu Ramalingam, [ ... ], Elangovan Vellaichamy

BtsCI and BseGI display sequence preference in the nucleotides flanking the recognition sequence

João Rosa, Esther Fernandez-Gonzalez, Cosimo Ducani, Björn Högberg

Characterization of biochemical properties of an apurinic/apyrimidinic endonuclease from Helicobacter pylori

Aigerim Turgimbayeva, Sailau Abeldenov, [ ... ], Bekbolat Khassenov

Unexpected binding behaviors of bacterial Argonautes in human cells cast doubts on their use as targetable gene regulators

Henriette O’Geen, Chonghua Ren, [ ... ], David J. Segal

Parallel mapping with site-directed hydroxyl radicals and micrococcal nuclease reveals structural features of positioned nucleosomes in vivo

Tomohiro Fuse, Koji Katsumata, [ ... ], Mitsuhiro Shimizu

Thermostable proteins bioprocesses: The activity of restriction endonuclease-methyltransferase from Thermus thermophilus (RM.TthHB27I) cloned in Escherichia coli is critically affected by the codon composition of the synthetic gene

Daria Krefft, Aliaksei Papkov, Agnieszka Zylicz-Stachula, Piotr M. Skowron

Antibacterial small molecules targeting the conserved TOPRIM domain of DNA gyrase

Scott S. Walker, Marc Labroli, [ ... ], Terry Roemer

DNA recognition by an RNA-guided bacterial Argonaute

Kevin W. Doxzen, Jennifer A. Doudna

RNA and DNA Targeting by a Reconstituted Thermus thermophilus Type III-A CRISPR-Cas System

Tina Y. Liu, Anthony T. Iavarone, Jennifer A. Doudna

Disruption of Higher Order DNA Structures in Friedreich’s Ataxia (GAA)_n Repeats by PNA or LNA Targeting

Helen Bergquist, Cristina S. J. Rocha, [ ... ], Rula Zain

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