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Cell physiology

Comprehensive analysis and experiment validation of five cuproptosis-related genes in prognosis, immune infiltration and metabolic characterization of pancreatic cancer

Qianxi Deng, Kun Yang, Qiaoling Liao, Xueli Tang, Honglin Quan, Guojun Yuan, Xia Hu, Zheng Jiang, Linju Wu

published 14 May 2025

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A comprehensive protocol for PDMS fabrication for use in cell culture

Aisling J. Greaney, Clíona M. McCarthy, Jishnu Padacherri Vethil, Mannthalah Abubaker, Erin C. Reardon, Frederick D. Crowley, Eoghan M. Cunnane, John J. E. Mulvihill

published 12 May 2025

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PDRN prevents SIRT1 degradation by attenuating autophagy during skin aging

Jingjing Chen, Fanshan Qiu, Jianfeng Shi, Wei Huang, Chenyu Zhao, Qianqian Han

published 09 May 2025

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Gene delivery of AGAT and GAMT boosts creatine levels in creatine transporter deficiency patient fibroblasts

Chloe Wells, Jon Sorgenfrei, Sadie L. Johnson, Devin Albertson, Jared Rutter, Steven Andrew Baker

published 08 May 2025

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Fatty acid metabolism suppresses neonatal cardiomyocyte proliferation by increasing PDK4 and HMGCS2 expression through PPARδ

Shota Tanaka, Akane Hirota, Yoshiaki Okada, Masanori Obana, Yasushi Fujio

published 08 May 2025

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Development and characterization of a 2D porcine colonic organoid model for studying intestinal physiology and barrier function

Masina Plenge, Nadine Schnepel, Mathias Müsken, Judith Rohde, Ralph Goethe, Gerhard Breves, Gemma Mazzuoli-Weber, Pascal Benz

published 07 May 2025

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Effects of fluid shear stress duration on the mechanical properties of HeLa cells using atomic force microscopy

Xinyao Zhao, Xiaolong Zhang, Fei Lei, Weikang Guo, Hui Yu, Yaoxian Wang

published 05 May 2025

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Integrated bulk RNA and single-cell analysis with experimental validation reveal oxidative stress-related diagnostic biomarkers for osteoporosis

Cheng Zhong, Liping Zhong

published 29 Apr 2025

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Mathematical modelling of reoviruses in cancer cell cultures

Arwa Abdulla Baabdulla, Francisca Cristi, Maya Shmulevitz, Thomas Hillen

published 28 Apr 2025

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Curcumin ameliorates aging-induced blood-testis barrier disruption by regulating AMPK/mTOR mediated autophagy

Chen Xue, Zhenxing Yan, Wenjing Cheng, Dong Zhang, Rong Zhang, Hongwei Duan, Lihong Zhang, Xiaofei Ma, Junjie Hu, Jian Kang, Xiaojun Ma

published 24 Apr 2025

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Lupenone preserves T cell activity by recovery of CD40L expression and protection from cytotoxicity due to methamphetamine exposure

Hyun-Su Lee, Eun-Nam Kim, Gil-Saeng Jeong

published 20 Mar 2025

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Targeting prostate cancer by new bispecific monocyte engager directed to prostate-specific membrane antigen

Gargi Das, Jakub Ptacek, Jana Campbell, Xintang Li, Barbora Havlinova, Satish kumar Noonepalle, Alejandro Villagra, Cyril Barinka, Zora Novakova

published 17 Mar 2025

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Digital PCR characterizes epithelial cell populations in murine duodenal organoids

Karla Acosta-Virgen, Hugo David González-Conchillos, Gabriela Vallejo-Flores, Lizbeth Iliana Salazar-Villatoro, Ernesto Guerrero-Sánchez, Adolfo Martínez-Palomo, Martha Espinosa-Cantellano

published 13 Mar 2025

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