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Cell physiology

Enhanced enfortumab vedotin sensitivity in a cisplatin-resistant bladder cancer model

Taisuke Tobe, Jun Teishima, [ ... ], Hideaki Miyake

Mechanistic insights into ENO2-driven glycolysis and tumor progression in hepatocellular carcinoma

Yan Liu, Xiao-Ran Zhang, [ ... ], Qiang Li

Oxidative stress-driven cellular heterogeneity in Knee Osteoarthritis: scRNA-seq pinpoints SPP1 and CYBA for diagnostic development

Yijiang Liu, Yiman Chi, Jiefeng Yin, Jun Yao

Single-cell analysis of COPD: Microenvironmental interactions driven by immune-fibrotic imbalance

Hong Jiang, Wenxing Wang, [ ... ], Jing Liang

Single-cell transcriptomics and machine learning characterize LTA4H-linked lipid metabolism and inflammatory signatures in the knee osteoarthritis IPFP/synovium compartment

Xin Chen, Shudong Li, [ ... ], Jifeng Zhao

3D CNN-CVAE and LSTM-guided de novo design of rotigotine derivatives targeting dopamine D1 and D3 receptors in restless legs syndrome

Sinan Eliaçık, Nouman Ali

Assessment of epithelial barrier integrity in cellular monolayer models using low cost, clinically approved fluorescent contrast agents

Elena Monfort Sanchez, Aaron F. Watson, [ ... ], Alex J. Thompson

Comparative transcriptomics reveals stage-specific regulatory pathways of ear thickening in Auricularia polytricha

Yi-Ning Huang, Li-Na Ke, Bin Yuan, Yongwen Lin

BCAM-AKT2 fusion protein promotes unfolded protein response driven oncogenic signaling in SKOV3 epithelial ovarian cancer cell line

Hala Khazem, Ravid Solomon Zemler, [ ... ], Ilan Bruchim

Androgenetic alopecia drugs and male infertility: Evidence from pharmacovigilance and testicular transcriptomics

Zhuozhi Gong, Jing He, [ ... ], Shengjing Liu

Identification of Galectin-9 (Gal-9) as a B7-H4 binding partner and characterization of their glycosylation-dependent interaction that modulates T cell signaling within a multi-ligand/receptor network

Ravear Zhiqiang Wang, Fang Yang, Jianhua Sui

Characterization of mesenchymal stromal cell-mediated mitochondrial transfer to healthy and diseased intervertebral disc cells

Ashley Cardenas, Noah Willett, [ ... ], Lawrence J. Bonassar

Mutations in the N-glycan branching enzyme MGAT1 promote invasiveness and EGF-stimulated proliferation and adhesion in neuroblastoma cells

M. Kristen Hall, Lyla J. Walker, Abel R. Messer, Ruth A. Schwalbe

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