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Cell physiology

Effect of orally administered cannabidiol oil on daily tonometric curve in healthy Italian Saddle horses

Marilena Bazzano, Fulvio Laus, Matteo Cerquetella, Andrea Spaterna, Andrea Marchegiani

published 28 May 2025

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Exploring the level of metabolic reprogramming and the role of prognostic factor SF3A3 in hepatocellular carcinoma through integrated single-cell landscape analysis

Wanshuo Wei, Yuan Gan, Xindan Zhang, Yumo Chen, Zengfeng Huang, Shuhan Wang, Xiaomei Xie, Yongle Li, Pengtao Qin, Lihe Jiang

published 27 May 2025

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A human antibody specific for SIRPα reprograms macrophages and promotes antibody mediated anti-cancer activity

Keifer G. Kurtz, Irina Lebedeva, Stephanie A. Pierre, David Andrew, Yu-Rou Liao, Daisy Ambriz, Olivia Vergnolle, Leyi Shen, Elizabeth Nyakatura, Manuel Baca, David A. Scheinberg

published 23 May 2025

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Stereocilium height changes can account for the calcium dependence of the outer-hair-cell bundle’s resting state

Rayan Chatterjee, Dáibhid Ó Maoiléidigh

published 23 May 2025

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Mechanistic studies of PFKFB2 reveal a novel inhibitor of its kinase activity

Craig Eyster, Satoshi Matsuzaki, Atul Pranay, Jennifer R. Giorgione, Anna Faakye, Mostafa Ahmed, Kenneth M. Humphries

published 22 May 2025

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Dynamic metabolic regulation of histone modifications during the yeast metabolic cycle

Bárbara Guzmán-Dinamarca, Raúl Conejeros, Marcelo Rivas-Astroza

published 20 May 2025

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Engineering of long-acting human growth hormone-Fc fusion proteins: Effects of valency, fusion position, and linker design on pharmacokinetics and efficacy

Taekyeol Lee, Dongsop Lee, Eunee Jung, Mikyung Son, Kyohwan Koo, Jaehoon Choi

published 15 May 2025

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Comprehensive analysis and experiment validation of five cuproptosis-related genes in prognosis, immune infiltration and metabolic characterization of pancreatic cancer

Qianxi Deng, Kun Yang, Qiaoling Liao, Xueli Tang, Honglin Quan, Guojun Yuan, Xia Hu, Zheng Jiang, Linju Wu

published 14 May 2025

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A comprehensive protocol for PDMS fabrication for use in cell culture

Aisling J. Greaney, Clíona M. McCarthy, Jishnu Padacherri Vethil, Mannthalah Abubaker, Erin C. Reardon, Frederick D. Crowley, Eoghan M. Cunnane, John J. E. Mulvihill

published 12 May 2025

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PDRN prevents SIRT1 degradation by attenuating autophagy during skin aging

Jingjing Chen, Fanshan Qiu, Jianfeng Shi, Wei Huang, Chenyu Zhao, Qianqian Han

published 09 May 2025

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Gene delivery of AGAT and GAMT boosts creatine levels in creatine transporter deficiency patient fibroblasts

Chloe Wells, Jon Sorgenfrei, Sadie L. Johnson, Devin Albertson, Jared Rutter, Steven Andrew Baker

published 08 May 2025

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Fatty acid metabolism suppresses neonatal cardiomyocyte proliferation by increasing PDK4 and HMGCS2 expression through PPARδ

Shota Tanaka, Akane Hirota, Yoshiaki Okada, Masanori Obana, Yasushi Fujio

published 08 May 2025

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Development and characterization of a 2D porcine colonic organoid model for studying intestinal physiology and barrier function

Masina Plenge, Nadine Schnepel, Mathias Müsken, Judith Rohde, Ralph Goethe, Gerhard Breves, Gemma Mazzuoli-Weber, Pascal Benz

published 07 May 2025

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