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Cell physiology

Analytical validation (accuracy, reproducibility, limit of detection) and gene expression analysis of FoundationOneRNA assay for fusion detection in 189 clinical tumor specimens

Daokun Sun, Richard S. P. Huang, Michelle Green, Chenming Cui, Saumya D. Sisoudiya, Andrej Savol, Chang Xu, Cui Guo, Joel Skoletsky, Justin M. Allen, Khaled Tolba, Varun Pattani, Alyssa Tarzia, Jennifer Whiting, Yanhua Tang, Lee A. Albacker, Christine Vietz, Michael Datto, Jie He, William Richard Jeck

published 12 Sep 2025

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Optimizing canine T cell activation, expansion, and transduction

Treyvon W. Davis, Jennifer C. Holmes, Arissa He, Paul R. Hess, Christopher L. Mariani, Yevgeny Brudno

published 11 Sep 2025

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HIV-1 controllers possess a unique CD8⁺ T cell activation phenotype and loss of control is associated with increased expression of exhaustion markers

Amber D. Jones, Zachary Capriotti, Erin Santos, Angel Lin, Rachel Van Duyne, Stephen Smith, Zachary Klase

published 28 Aug 2025

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The role of ephaptic coupling and gap junctional coupling in modulating the initiation and dynamics of reentrant arrhythmias

Ning Wei, Elena G. Tolkacheva

published 19 Aug 2025

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Association between Endothelial Activation and Stress Index and mortality in diabetic nephropathy ICU patients: A retrospective cohort study

Sheng Chen, Lin Guo, Xiaohan Ma, Shuaikang Wang, Junchao Wu, Lingling Wu, Ting Zhang, Hongjun Gao

published 14 Aug 2025

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Amino acid residues 655 and 969 in the spike protein of Omicron subvariant BA.1 control use of TMPRSS2 versus Cathepsin L dependent entry pathways and cell tropism

Cheila Rocha, Prerna Arora, Lu Zhang, Anzhalika Sidarovich, Luise Graichen, Anna-Sophie Moldenhauer, Stefan Pöhlmann, Markus Hoffmann

published 14 Aug 2025

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Comparative proteomics of HepG2 cells reveals NGLY1 as an important regulator of ferroptosis resistance and iron uptake

Stuart Emmerson, Haruhiko Fujihira, Takehiro Suzuki, Naoshi Dohmae, Peter Greimel, Yoshio Hirabayashi, Tadashi Suzuki

published 14 Aug 2025

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Development of a tissue-specific bioscaffold for intestinal stem cell culture

Sachin Kakar, Mathieu F. Derouet, Liyue Zhang, Connor J. Gillis, Frederikke Larsen, Arghya Paul, Lauren E. Flynn, Samuel Asfaha

published 06 Aug 2025

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Hyperuricemia in ob/ob mice relates to hepatocellular pyruvate metabolism/ xanthine oxidase axis

Shan Zhang, Shasha Hu, Haibo Tan, Ertao Jia

published 06 Aug 2025

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Establishing a non-viral transfection system for fibroblasts using branched polyethylenimine

Tim Lukas Lübbersmeyer, Kirsten Wissel, Andrea Hoffmann, Lisa Kötter, Thomas Lenarz, Gerrit Paasche

published 05 Aug 2025

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scFv intrabody targeting wildtype TDP-43 presents protective effects in a cellular model of TDP-43 proteinopathy

Yara Al Ojaimi, Rudolf Hergesheimer, Anna A. Chami, Hugo Alarcan, Johanna Augros, Audrey Dangoumau, Shanez Haouari, Jérôme Bourgeais, Antoine Lefevre, Samira Osman, Patrick Emond, Patrick Vourc’h, Christian R. Andres, Philippe Corcia, Olivier Herault, Pierre Martineau, Débora Lanznaster, Hélène Blasco

published 04 Aug 2025

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Single cell transcriptomic analysis reveals transcriptome differences of different cells between eosinophilic chronic rhinosinusitis with nasal polyps and non-eosinophilic chronic rhinosinusitis with nasal polyps

Ying Jin, Yuanshan Liang, Zhijun Wang, Yiting Jiang, Fayang Yuan, Tian Zhang

published 28 Jul 2025

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A role for Myo-II zipper and spaghetti squash in Gliotactin-dependent Drosophila melanogaster wing hair planar cell polarity

Chase Holland, Natalya Cox, Hanna Dery, Mariah Williams, Gwendolyn Jones, Lindi Newton, Kristin Jurgensen, Han Chang, Alex Hord, Won Chang, Damon Montgomery, Hawkins Hochstedler, Amish Mishra, Jessica Baker

published 23 Jul 2025

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