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Cell physiology

PFKP is transcriptionally repressed by BRCA1/ZBRK1 and predicts prognosis in breast cancer

Danna Yeerken, Ruoxi Hong, [ ... ], Qimin Zhan

Cholinergic-like neurons carrying PSEN1 E280A mutation from familial Alzheimer’s disease reveal intraneuronal sAPPβ fragments accumulation, hyperphosphorylation of TAU, oxidative stress, apoptosis and Ca²⁺ dysregulation: Therapeutic implications

Viviana Soto-Mercado, Miguel Mendivil-Perez, [ ... ], Marlene Jimenez-Del-Rio

Distinct patterns of dentate gyrus cell activation distinguish physiologic from aberrant stimuli

Jason C. You, Kavitha Muralidharan, [ ... ], Jeannie Chin

Application of co-culture technology of epithelial type cells and mesenchymal type cells using nanopatterned structures

Taek-Hee Jung, Eun-Bin Chung, [ ... ], Sung-Hwan Moon

Addressing the role of centromere sites in activation of ParB proteins for partition complex assembly

Sylvain Audibert, Nicolas Tanguy-le-Gac, [ ... ], David Lane

Theoretical investigation of a genetic switch for metabolic adaptation

Kathrin S. Laxhuber, Muir J. Morrison, [ ... ], Rob Phillips

The role of changing temperature in microbial metabolic processes during permafrost thaw

Komi S. Messan, Robert M. Jones, [ ... ], Robyn A. Barbato

Reduced cellular binding affinity has profoundly different impacts on the spread of distinct poxviruses

Erica B. Flores, Mee Y. Bartee, Eric Bartee

The SQSTM1-NUP214 fusion protein interacts with Crm1, activates Hoxa and Meis1 genes, and drives leukemogenesis in mice

Catherine P. Lavau, Waitman K. Aumann, [ ... ], Daniel S. Wechsler

INCB054828 (pemigatinib), a potent and selective inhibitor of fibroblast growth factor receptors 1, 2, and 3, displays activity against genetically defined tumor models

Phillip C. C. Liu, Holly Koblish, [ ... ], Gregory Hollis

Podocyte RNA sequencing reveals Wnt- and ECM-associated genes as central in FSGS

Eva Nora Bukosza, Klaus Kratochwill, [ ... ], Christoph A. Gebeshuber

Highly efficient serum-free manipulation of miRNA in human NK cells without loss of viability or phenotypic alterations is accomplished with TransIT-TKO

Breanna K. V. Hargreaves, Sarah E. Roberts, Beata Derfalvi, Jeanette E. Boudreau

Blood co-expression modules identify potential modifier genes of diabetes and lung function in cystic fibrosis

Fanny Pineau, Davide Caimmi, [ ... ], Albertina De Sario

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