January 2017

Human neutrophils and monocytes bound to a Brugia malayi microfilaria. Microfilaria were incubated with the human cells for 24 hours and then collected by Cytospin. The preparation was stained for DNA (DAPI - blue), neutrophils (CD-16 - green), monocytes (CD-14 - red) and human neutrophil elastase (purple). McCoy et al.

Image Credit: Barbara Reaves

Viewpoints

Bibliometric Indicators of the Zika Outbreak

Priscila C. Albuquerque, Mauro Jorge C. Castro, Juliana Santos-Gandelman, Ana Claudia Oliveira, José M. Peralta, Marcio L. Rodrigues

PLOS Neglected Tropical Diseases: published January 19, 2017 | https://doi.org/10.1371/journal.pntd.0005132

Rationale for Further Development of a Vaccine Based on the Circumsporozoite Protein of Plasmodium vivax

Anjali Yadava, Norman C. Waters

PLOS Neglected Tropical Diseases: published January 12, 2017 | https://doi.org/10.1371/journal.pntd.0005164

The Case for Maternal Postpartum Deworming

Layla S. Mofid, Theresa W. Gyorkos

PLOS Neglected Tropical Diseases: published January 5, 2017 | https://doi.org/10.1371/journal.pntd.0005203

Potential Value of Triple Drug Therapy with Ivermectin, Diethylcarbamazine, and Albendazole (IDA) to Accelerate Elimination of Lymphatic Filariasis and Onchocerciasis in Africa

Peter U. Fischer, Christopher L. King, Julie A. Jacobson, Gary J. Weil

PLOS Neglected Tropical Diseases: published January 5, 2017 | https://doi.org/10.1371/journal.pntd.0005163

Development of Diagnostics for Chagas Disease: Where Should We Put Our Limited Resources?

Albert Picado, Andrea Angheben, Andrea Marchiol, Belkisyolé Alarcón de Noya, Laurence Flevaud, Maria Jesus Pinazo, Montserrat Gállego, Sheba Meymandi, Silvia Moriana

PLOS Neglected Tropical Diseases: published January 5, 2017 | https://doi.org/10.1371/journal.pntd.0005148

Policy Platform

Investments in Research and Surveillance Are Needed to Go Beyond Elimination and Stop Transmission of Leishmania in the Indian Subcontinent

Piero L. Olliaro, Tushar A. K. M. Shamsuzzaman, Baburam Marasini, A. C. Dhariwal, Ahmed Be-Nazir, Dinesh Mondal, Megha Raj Banjara, Pradeep Das, Shyam Sundar, Suman Rijal, Byron Arana, Jorge Alvar, Daniel Argaw, Rosanna W. Peeling, Axel Kroeger, Greg Matlashewski

PLOS Neglected Tropical Diseases: published January 26, 2017 | https://doi.org/10.1371/journal.pntd.0005190

Integrated Control and Management of Neglected Tropical Skin Diseases

Oriol Mitjà, Michael Marks, Laia Bertran, Karsor Kollie, Daniel Argaw, Ahmed H. Fahal, Christopher Fitzpatrick, L. Claire Fuller, Bernardo Garcia Izquierdo, Roderick Hay, Norihisa Ishii, Christian Johnson, Jeffrey V. Lazarus, Anthony Meka, Michele Murdoch, Sally-Ann Ohene, Pam Small, Andrew Steer, Earnest N. Tabah, Alexandre Tiendrebeogo, Lance Waller, Rie Yotsu, Stephen L. Walker, Kingsley Asiedu

PLOS Neglected Tropical Diseases: published January 19, 2017 | https://doi.org/10.1371/journal.pntd.0005136

From Innovation to Application

Biospecimen Repositories and Integrated Databases as Critical Infrastructure for Pathogen Discovery and Pathobiology Research

Jonathan L. Dunnum, Richard Yanagihara, Karl M. Johnson, Blas Armien, Nyamsuren Batsaikhan, Laura Morgan, Joseph A. Cook

PLOS Neglected Tropical Diseases: published January 26, 2017 | https://doi.org/10.1371/journal.pntd.0005133

A Mobile Platform Enables Unprecedented Sanitation Uptake in Zambia

Laurie Markle, Abel Maganani, Oswell Katooka, Amy Tiwari, Nicolas Osbert, David A. Larsen, Benjamin Winters

PLOS Neglected Tropical Diseases: published January 12, 2017 | https://doi.org/10.1371/journal.pntd.0005131

Research Articles

Distinct antibody responses of patients with mild and severe leptospirosis determined by whole proteome microarray analysis

Carolina Lessa-Aquino, Janet C. Lindow, Arlo Randall, Elsio Wunder, Jozelyn Pablo, Rie Nakajima, Algis Jasinskas, Jaqueline S. Cruz, Alcineia O. Damião, Nívison Nery, Guilherme S. Ribeiro, Federico Costa, José E. Hagan, Mitermayer Galvão Reis, Albert I. Ko, Marco Alberto Medeiros, Philip L. Felgner

PLOS Neglected Tropical Diseases: published January 31, 2017 | https://doi.org/10.1371/journal.pntd.0005349

Modeling Powassan virus infection in Peromyscus leucopus, a natural host

Luwanika Mlera, Kimberly Meade-White, Greg Saturday, Dana Scott, Marshall E. Bloom

PLOS Neglected Tropical Diseases: published January 31, 2017 | https://doi.org/10.1371/journal.pntd.0005346

The significant scale up and success of Transmission Assessment Surveys 'TAS' for endgame surveillance of lymphatic filariasis in Bangladesh: One step closer to the elimination goal of 2020

A. K. M. Shamsuzzaman, Rouseli Haq, Mohammad J. Karim, Motasim B. Azad, A. S. M. Sultan Mahmood, Abul Khair, Muhammad Mujibur Rahman, Israt Hafiz, K. D. Ramaiah, Charles D. Mackenzie, Hayley E. Mableson, Louise A. Kelly-Hope

PLOS Neglected Tropical Diseases: published January 31, 2017 | https://doi.org/10.1371/journal.pntd.0005340

Intestinal parasites and vector-borne pathogens in stray and free-roaming cats living in continental and insular Greece

Anastasia Diakou, Angela Di Cesare, Paolo Matteo Accettura, Luciano Barros, Raffaella Iorio, Barbara Paoletti, Antonio Frangipane di Regalbono, Lénaïg Halos, Frederic Beugnet, Donato Traversa

PLOS Neglected Tropical Diseases: published January 31, 2017 | https://doi.org/10.1371/journal.pntd.0005335

Dispersal of male and female Culex quinquefasciatus and Aedes albopictus mosquitoes using stable isotope enrichment

Matthew C. I. Medeiros, Emily C. Boothe, E. Brendan Roark, Gabriel L. Hamer

PLOS Neglected Tropical Diseases: published January 30, 2017 | https://doi.org/10.1371/journal.pntd.0005347

Genetic evidence for a worldwide chaotic dispersion pattern of the arbovirus vector, Aedes albopictus

Mosè Manni, Carmela R. Guglielmino, Francesca Scolari, Anubis Vega-Rúa, Anna-Bella Failloux, Pradya Somboon, Antonella Lisa, Grazia Savini, Mariangela Bonizzoni, Ludvik M. Gomulski, Anna R. Malacrida, Giuliano Gasperi

PLOS Neglected Tropical Diseases: published January 30, 2017 | https://doi.org/10.1371/journal.pntd.0005332

Cellular Immune Responses to Live Attenuated Japanese Encephalitis (JE) Vaccine SA14-14-2 in Adults in a JE/Dengue Co-Endemic Area

Lance Turtle, Filippo Tatullo, Tanushka Bali, Vasanthapuram Ravi, Mohammed Soni, Sajesh Chan, Savita Chib, Manjunatha M. Venkataswamy, Prachi Fadnis, Mansour Yaïch, Stefan Fernandez, Paul Klenerman, Vijaya Satchidanandam, Tom Solomon

PLOS Neglected Tropical Diseases: published January 30, 2017 | https://doi.org/10.1371/journal.pntd.0005263

Identification of three immunodominant motifs with atypical isotype profile scattered over the Onchocerca volvulus proteome

Ole Lagatie, Bieke Van Dorst, Lieven J. Stuyver

PLOS Neglected Tropical Diseases: published January 26, 2017 | https://doi.org/10.1371/journal.pntd.0005330

Molecular Mimicry between Chikungunya Virus and Host Components: A Possible Mechanism for the Arthritic Manifestations

Vijayalakshmi Reddy, Anita Desai, Shankar Susarla Krishna, Ravi Vasanthapuram

PLOS Neglected Tropical Diseases: published January 26, 2017 | https://doi.org/10.1371/journal.pntd.0005238

Investigation of a Medieval Pilgrim Burial Excavated from the Leprosarium of St Mary Magdalen Winchester, UK

Simon Roffey, Katie Tucker, Kori Filipek-Ogden, Janet Montgomery, Jamie Cameron, Tamsin O’Connell, Jane Evans, Phil Marter, G. Michael Taylor

PLOS Neglected Tropical Diseases: published January 26, 2017 | https://doi.org/10.1371/journal.pntd.0005186

Characterizing Antibody Responses to Plasmodium vivax and Plasmodium falciparum Antigens in India Using Genome-Scale Protein Microarrays

Swapna Uplekar, Pavitra Nagesh Rao, Lalitha Ramanathapuram, Vikky Awasthi, Kalpana Verma, Patrick Sutton, Syed Zeeshan Ali, Ankita Patel, Sri Lakshmi Priya G., Sangamithra Ravishankaran, Nisha Desai, Nikunj Tandel, Sandhya Choubey, Punam Barla, Deena Kanagaraj, Alex Eapen, Khageswar Pradhan, Ranvir Singh, Aarti Jain, Philip L. Felgner, D. Huw Davies, Jane M. Carlton, Jyoti Das

PLOS Neglected Tropical Diseases: published January 24, 2017 | https://doi.org/10.1371/journal.pntd.0005323

Differential Expression of Matrix Metalloproteinases 2, 9 and Cytokines by Neutrophils and Monocytes in the Clinical Forms of Chagas Disease

Nayara I. Medeiros, Rafaelle C. G. Fares, Eliza P. Franco, Giovane R. Sousa, Rafael T. Mattos, Ana T. Chaves, Maria do Carmo P. Nunes, Walderez O. Dutra, Rodrigo Correa-Oliveira, Manoel O. C. Rocha, Juliana A. S. Gomes

PLOS Neglected Tropical Diseases: published January 24, 2017 | https://doi.org/10.1371/journal.pntd.0005284

Integrated Mapping of Yaws and Trachoma in the Five Northern-Most Provinces of Vanuatu

Fasihah Taleo, Colin K Macleod, Michael Marks, Oliver Sokana, Anna Last, Rebecca Willis, Mackline Garae, Annie Bong, Brian K Chu, Paul Courtright, Jacob Kool, George Taleo, Jean Jacque Rory, Anthony W Solomon, Global Trachoma Mapping Project

PLOS Neglected Tropical Diseases: published January 24, 2017 | https://doi.org/10.1371/journal.pntd.0005267

Unrecognized Emergence of Chikungunya Virus during a Zika Virus Outbreak in Salvador, Brazil

Cristiane W. Cardoso, Mariana Kikuti, Ana Paula P. B. Prates, Igor A. D. Paploski, Laura B. Tauro, Monaise M. O. Silva, Perla Santana, Marta F. S. Rego, Mitermayer G. Reis, Uriel Kitron, Guilherme S. Ribeiro

PLOS Neglected Tropical Diseases: published January 23, 2017 | https://doi.org/10.1371/journal.pntd.0005334

A Comparison of the Quality of Informed Consent for Clinical Trials of an Experimental Hookworm Vaccine Conducted in Developed and Developing Countries

David J. Diemert, Lucas Lobato, Ashley Styczynski, Maria Zumer, Amanda Soares, Maria Flávia Gazzinelli

PLOS Neglected Tropical Diseases: published January 23, 2017 | https://doi.org/10.1371/journal.pntd.0005327

Evaluation and Monitoring of Mycobacterium leprae Transmission in Household Contacts of Patients with Hansen's Disease in Colombia

Marcela Romero-Montoya, Juan Camilo Beltran-Alzate, Nora Cardona-Castro

PLOS Neglected Tropical Diseases: published January 23, 2017 | https://doi.org/10.1371/journal.pntd.0005325

Identification of Functional Determinants in the Chikungunya Virus E2 Protein

Christopher Weber, Eva Berberich, Christine von Rhein, Lisa Henß, Eberhard Hildt, Barbara S. Schnierle

PLOS Neglected Tropical Diseases: published January 23, 2017 | https://doi.org/10.1371/journal.pntd.0005318

Spatial Analysis of Dengue Seroprevalence and Modeling of Transmission Risk Factors in a Dengue Hyperendemic City of Venezuela

Maria F. Vincenti-Gonzalez, María-Eugenia Grillet, Zoraida I. Velasco-Salas, Erley F. Lizarazo, Manuel A. Amarista, Gloria M. Sierra, Guillermo Comach, Adriana Tami

PLOS Neglected Tropical Diseases: published January 23, 2017 | https://doi.org/10.1371/journal.pntd.0005317

Modelling Anti-Ov16 IgG4 Antibody Prevalence as an Indicator for Evaluation and Decision Making in Onchocerciasis Elimination Programmes

Yvonne L. Lont, Luc E. Coffeng, Sake J. de Vlas, Allison Golden, Tala de los Santos, Gonzalo J. Domingo, Wilma A. Stolk

PLOS Neglected Tropical Diseases: published January 23, 2017 | https://doi.org/10.1371/journal.pntd.0005314

Predicted Spatial Spread of Canine Rabies in Australia

Simon P. Johnstone-Robertson, Peter J. S. Fleming, Michael P. Ward, Stephen A. Davis

PLOS Neglected Tropical Diseases: published January 23, 2017 | https://doi.org/10.1371/journal.pntd.0005312

Identification of BALB/c Immune Markers Correlated with a Partial Protection to Leishmania infantum after Vaccination with a Rationally Designed Multi-epitope Cysteine Protease A Peptide-Based Nanovaccine

Maria Agallou, Maritsa Margaroni, Evita Athanasiou, Dimitra K. Toubanaki, Katerina Kontonikola, Konstantina Karidi, Olga Kammona, Costas Kiparissides, Evdokia Karagouni

PLOS Neglected Tropical Diseases: published January 23, 2017 | https://doi.org/10.1371/journal.pntd.0005311

Diagnosing Polyparasitism in a High-Prevalence Setting in Beira, Mozambique: Detection of Intestinal Parasites in Fecal Samples by Microscopy and Real-Time PCR

Lynn Meurs, Anton M. Polderman, Natalie V. S. Vinkeles Melchers, Eric A. T. Brienen, Jaco J. Verweij, Bernhard Groosjohan, Felisberto Mendes, Manito Mechendura, Dagmar H. Hepp, Marijke C. C. Langenberg, Rosanne Edelenbosch, Katja Polman, Lisette van Lieshout

PLOS Neglected Tropical Diseases: published January 23, 2017 | https://doi.org/10.1371/journal.pntd.0005310

GRAIL and Otubain-1 are Related to T Cell Hyporesponsiveness during Trypanosoma cruzi Infection

Cinthia C. Stempin, Jorge D. Rojas Marquez, Yamile Ana, Fabio M. Cerban

PLOS Neglected Tropical Diseases: published January 23, 2017 | https://doi.org/10.1371/journal.pntd.0005307

Pyrethroid Resistance in Malaysian Populations of Dengue Vector Aedes aegypti Is Mediated by CYP9 Family of Cytochrome P450 Genes

Intan H. Ishak, Basile Kamgang, Sulaiman S. Ibrahim, Jacob M. Riveron, Helen Irving, Charles S. Wondji

PLOS Neglected Tropical Diseases: published January 23, 2017 | https://doi.org/10.1371/journal.pntd.0005302

Eyelash Epilation in the Absence of Trichiasis: Results of a Population-Based Prevalence Survey in the Western Division of Fiji

Colin Macleod, Chelsea Yalen, Robert Butcher, Umesh Mudaliar, Kinisimere Natutusau, Mere Rainima-Qaniuci, Chris Haffenden, Conall Watson, Naomi Cocks, Luisa Cikamatana, Chrissy H. Roberts, Michael Marks, Eric Rafai, David C. W. Mabey, Mike Kama, Anthony W. Solomon

PLOS Neglected Tropical Diseases: published January 23, 2017 | https://doi.org/10.1371/journal.pntd.0005277

Seroprevalence of Chikungunya Virus in a Rural Community in Brazil

Rivaldo V. Cunha, Karen S. Trinta, Camila A. Montalbano, Michel V. F. Sucupira, Maricelia M. de Lima, Erenilde Marques, Izilyanne H. Romanholi, Julio Croda

PLOS Neglected Tropical Diseases: published January 20, 2017 | https://doi.org/10.1371/journal.pntd.0005319

Whole Genome Amplification and Reduced-Representation Genome Sequencing of Schistosoma japonicum Miracidia

Jonathan A. Shortt, Daren C. Card, Drew R. Schield, Yang Liu, Bo Zhong, Todd A. Castoe, Elizabeth J. Carlton, David D. Pollock

PLOS Neglected Tropical Diseases: published January 20, 2017 | https://doi.org/10.1371/journal.pntd.0005292

Impact of CD4+ T Cell Responses on Clinical Outcome following Oral Administration of Wild-Type Enterotoxigenic Escherichia coli in Humans

Monica A. McArthur, Wilbur H. Chen, Laurence Magder, Myron M. Levine, Marcelo B. Sztein

PLOS Neglected Tropical Diseases: published January 19, 2017 | https://doi.org/10.1371/journal.pntd.0005291

Evaluation of a Smartphone Decision-Support Tool for Diarrheal Disease Management in a Resource-Limited Setting

Farhana Haque, Robyn L. Ball, Selina Khatun, Mujaddeed Ahmed, Saraswati Kache, Mohammod Jobayer Chisti, Shafiqul Alam Sarker, Stace D. Maples, Dane Pieri, Teja Vardhan Korrapati, Clea Sarnquist, Nancy Federspiel, Muhammad Waliur Rahman, Jason R. Andrews, Mahmudur Rahman, Eric Jorge Nelson

PLOS Neglected Tropical Diseases: published January 19, 2017 | https://doi.org/10.1371/journal.pntd.0005290

The Socioeconomic Benefit to Individuals of Achieving the 2020 Targets for Five Preventive Chemotherapy Neglected Tropical Diseases

William K. Redekop, Edeltraud J. Lenk, Marianne Luyendijk, Christopher Fitzpatrick, Louis Niessen, Wilma A. Stolk, Fabrizio Tediosi, Adriana J. Rijnsburger, Roel Bakker, Jan A. C. Hontelez, Jan H. Richardus, Julie Jacobson, Sake J. de Vlas, Johan L. Severens

PLOS Neglected Tropical Diseases: published January 19, 2017 | https://doi.org/10.1371/journal.pntd.0005289

Mitigating Diseases Transmitted by Aedes Mosquitoes: A Cluster-Randomised Trial of Permethrin-Impregnated School Uniforms

Pattamaporn Kittayapong, Phanthip Olanratmanee, Pongsri Maskhao, Peter Byass, James Logan, Yesim Tozan, Valérie Louis, Duane J. Gubler, Annelies Wilder-Smith

PLOS Neglected Tropical Diseases: published January 19, 2017 | https://doi.org/10.1371/journal.pntd.0005197

"I Cannot Be Worried": Living with Chagas Disease in Tropical Bolivia

Colin J. Forsyth

PLOS Neglected Tropical Diseases: published January 18, 2017 | https://doi.org/10.1371/journal.pntd.0005251

Exacerbated Leishmaniasis Caused by a Viral Endosymbiont can be Prevented by Immunization with Its Viral Capsid

Patrik Castiglioni, Mary-Anne Hartley, Matteo Rossi, Florence Prevel, Chantal Desponds, Daniel T. Utzschneider, Remzi-Onur Eren, Haroun Zangger, Livia Brunner, Nicolas Collin, Dietmar Zehn, F. Matthew Kuhlmann, Stephen M. Beverley, Nicolas Fasel, Catherine Ronet

PLOS Neglected Tropical Diseases: published January 18, 2017 | https://doi.org/10.1371/journal.pntd.0005240

Defining Seropositivity Thresholds for Use in Trachoma Elimination Studies

Stephanie J. Migchelsen, Diana L. Martin, Khamphoua Southisombath, Patrick Turyaguma, Anne Heggen, Peter Paul Rubangakene, Hassan Joof, Pateh Makalo, Gretchen Cooley, Sarah Gwyn, Anthony W. Solomon, Martin J. Holland, Paul Courtright, Rebecca Willis, Neal D. E. Alexander, David C. W. Mabey, Chrissy h. Roberts

PLOS Neglected Tropical Diseases: published January 18, 2017 | https://doi.org/10.1371/journal.pntd.0005230

MLST-Based Population Genetic Analysis in a Global Context Reveals Clonality amongst Cryptococcus neoformans var. grubii VNI Isolates from HIV Patients in Southeastern Brazil

Kennio Ferreira-Paim, Leonardo Andrade-Silva, Fernanda M. Fonseca, Thatiana B. Ferreira, Delio J. Mora, Juliana Andrade-Silva, Aziza Khan, Aiken Dao, Eduardo C. Reis, Margarete T. G. Almeida, Andre Maltos, Virmondes R. Junior, Luciana Trilles, Volker Rickerts, Ariya Chindamporn, Jane E. Sykes, Massimo Cogliati, Kirsten Nielsen, Teun Boekhout, Matthew Fisher, June Kwon-Chung, David M. Engelthaler, Marcia Lazéra, Wieland Meyer, Mario L. Silva-Vergara

PLOS Neglected Tropical Diseases: published January 18, 2017 | https://doi.org/10.1371/journal.pntd.0005223

Schistosoma mansoni Infection of Mice, Rats and Humans Elicits a Strong Antibody Response to a Limited Number of Reduction-Sensitive Epitopes on Five Major Tegumental Membrane Proteins

Greice Krautz-Peterson, Michelle Debatis, Jacqueline M. Tremblay, Sergio C. Oliveira, Akram A. Da’dara, Patrick J. Skelly, Charles B. Shoemaker

PLOS Neglected Tropical Diseases: published January 17, 2017 | https://doi.org/10.1371/journal.pntd.0005306

High-Throughput Carbon Substrate Profiling of Mycobacterium ulcerans Suggests Potential Environmental Reservoirs

Dezemon Zingue, Amar Bouam, Muriel Militello, Michel Drancourt

PLOS Neglected Tropical Diseases: published January 17, 2017 | https://doi.org/10.1371/journal.pntd.0005303

Epidemiology and Molecular Typing of Trypanosoma cruzi in Naturally-Infected Hound Dogs and Associated Triatomine Vectors in Texas, USA

Rachel Curtis-Robles, Karen F. Snowden, Brandon Dominguez, Lewis Dinges, Sandy Rodgers, Glennon Mays, Sarah A. Hamer

PLOS Neglected Tropical Diseases: published January 17, 2017 | https://doi.org/10.1371/journal.pntd.0005298

Detection of a Potential New Bartonella Species “Candidatus Bartonella rondoniensis” in Human Biting Kissing Bugs (Reduviidae; Triatominae)

Maureen Laroche, Jean-Michel Berenger, Oleg Mediannikov, Didier Raoult, Philippe Parola

PLOS Neglected Tropical Diseases: published January 17, 2017 | https://doi.org/10.1371/journal.pntd.0005297

Cytoplasmic Localization of HTLV-1 HBZ Protein: A Biomarker of HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP)

Marco Baratella, Greta Forlani, Goutham U. Raval, Alessandra Tedeschi, Olivier Gout, Antoine Gessain, Giovanna Tosi, Roberto S. Accolla

PLOS Neglected Tropical Diseases: published January 17, 2017 | https://doi.org/10.1371/journal.pntd.0005285

Defining the Risk of Zika and Chikungunya Virus Transmission in Human Population Centers of the Eastern United States

Carrie A. Manore, Richard S. Ostfeld, Folashade B. Agusto, Holly Gaff, Shannon L. LaDeau

PLOS Neglected Tropical Diseases: published January 17, 2017 | https://doi.org/10.1371/journal.pntd.0005255

Forecasting Zika Incidence in the 2016 Latin America Outbreak Combining Traditional Disease Surveillance with Search, Social Media, and News Report Data

Sarah F. McGough, John S. Brownstein, Jared B. Hawkins, Mauricio Santillana

PLOS Neglected Tropical Diseases: published January 13, 2017 | https://doi.org/10.1371/journal.pntd.0005295

European Aedes albopictus and Culex pipiens Are Competent Vectors for Japanese Encephalitis Virus

Mélissanne de Wispelaere, Philippe Desprès, Valérie Choumet

PLOS Neglected Tropical Diseases: published January 13, 2017 | https://doi.org/10.1371/journal.pntd.0005294

Comparative Ability of Oropsylla montana and Xenopsylla cheopis Fleas to Transmit Yersinia pestis by Two Different Mechanisms

B. Joseph Hinnebusch, David M. Bland, Christopher F. Bosio, Clayton O. Jarrett

PLOS Neglected Tropical Diseases: published January 12, 2017 | https://doi.org/10.1371/journal.pntd.0005276

A Pan-Lyssavirus Taqman Real-Time RT-PCR Assay for the Detection of Highly Variable Rabies virus and Other Lyssaviruses

Ashutosh Wadhwa, Kimberly Wilkins, Jinxin Gao, Rene Edgar Condori Condori, Crystal M. Gigante, Hui Zhao, Xiaoyue Ma, James A. Ellison, Lauren Greenberg, Andres Velasco-Villa, Lillian Orciari, Yu Li

PLOS Neglected Tropical Diseases: published January 12, 2017 | https://doi.org/10.1371/journal.pntd.0005258

Epidemiology of Chikungunya Virus Outbreaks in Guadeloupe and Martinique, 2014: An Observational Study in Volunteer Blood Donors

Pierre Gallian, Isabelle Leparc-Goffart, Pascale Richard, Françoise Maire, Olivier Flusin, Rachid Djoudi, Jacques Chiaroni, Remi Charrel, Pierre Tiberghien, Xavier de Lamballerie

PLOS Neglected Tropical Diseases: published January 12, 2017 | https://doi.org/10.1371/journal.pntd.0005254

Yersinia enterocolitica, a Neglected Cause of Human Enteric Infections in Côte d’Ivoire

Daniel Saraka, Cyril Savin, Stephane Kouassi, Bakary Cissé, Eugène Koffi, Nicolas Cabanel, Sylvie Brémont, Hortense Faye-Kette, Mireille Dosso, Elisabeth Carniel

PLOS Neglected Tropical Diseases: published January 12, 2017 | https://doi.org/10.1371/journal.pntd.0005216

Isolation of Novel Trypanosomatid, Zelonia australiensis sp. nov. (Kinetoplastida: Trypanosomatidae) Provides Support for a Gondwanan Origin of Dixenous Parasitism in the Leishmaniinae

Joel Barratt, Alexa Kaufer, Bryce Peters, Douglas Craig, Andrea Lawrence, Tamalee Roberts, Rogan Lee, Gary McAuliffe, Damien Stark, John Ellis

PLOS Neglected Tropical Diseases: published January 12, 2017 | https://doi.org/10.1371/journal.pntd.0005215

Transient In Vivo Resistance Mechanisms of Burkholderia pseudomallei to Ceftazidime and Molecular Markers for Monitoring Treatment Response

Jason E. Cummings, Richard A. Slayden

PLOS Neglected Tropical Diseases: published January 12, 2017 | https://doi.org/10.1371/journal.pntd.0005209

Rapid Genotyping of β-tubulin Polymorphisms in Trichuris trichiura and Ascaris lumbricoides

Nour Rashwan, Marilyn Scott, Roger Prichard

PLOS Neglected Tropical Diseases: published January 12, 2017 | https://doi.org/10.1371/journal.pntd.0005205

“I Wasted 3 Years, Thinking It’s Not a Problem”: Patient and Health System Delays in Diagnosis of Leprosy in India: A Mixed-Methods Study

Thirumugam Muthuvel, Srinivas Govindarajulu, Petros Isaakidis, Hemant Deepak Shewade, Vasudev Rokade, Rajbir Singh, Sanjeev Kamble

PLOS Neglected Tropical Diseases: published January 12, 2017 | https://doi.org/10.1371/journal.pntd.0005192

Engineered Aedes aegypti JAK/STAT Pathway-Mediated Immunity to Dengue Virus

Natapong Jupatanakul, Shuzhen Sim, Yesseinia I. Angleró-Rodríguez, Jayme Souza-Neto, Suchismita Das, Kristin E. Poti, Shannan L. Rossi, Nicholas Bergren, Nikos Vasilakis, George Dimopoulos

PLOS Neglected Tropical Diseases: published January 12, 2017 | https://doi.org/10.1371/journal.pntd.0005187

Emergence of Rare Species of Nontuberculous Mycobacteria as Potential Pathogens in Saudi Arabian Clinical Setting

Bright Varghese, Mushira Enani, Mohammed Shoukri, Sahar AlThawadi, Sameera AlJohani, Sahal Al- Hajoj

PLOS Neglected Tropical Diseases: published January 11, 2017 | https://doi.org/10.1371/journal.pntd.0005288

A Single Dose Oral Azithromycin versus Intramuscular Benzathine Penicillin for the Treatment of Yaws-A Randomized Non Inferiority Trial in Ghana

Cynthia Kwakye-Maclean, Nsiire Agana, John Gyapong, Priscilia Nortey, Yaw Adu-Sarkodie, Esther Aryee, Kingsley Asiedu, Roland Ballard, Fred Binka

PLOS Neglected Tropical Diseases: published January 10, 2017 | https://doi.org/10.1371/journal.pntd.0005154

Neuropathogenesis of Zika Virus in a Highly Susceptible Immunocompetent Mouse Model after Antibody Blockade of Type I Interferon

Darci R. Smith, Bradley Hollidge, Sharon Daye, Xiankun Zeng, Candace Blancett, Kyle Kuszpit, Thomas Bocan, Jeff W. Koehler, Susan Coyne, Tim Minogue, Tara Kenny, Xiaoli Chi, Soojin Yim, Lynn Miller, Connie Schmaljohn, Sina Bavari, Joseph W. Golden

PLOS Neglected Tropical Diseases: published January 9, 2017 | https://doi.org/10.1371/journal.pntd.0005296

The Fleas (Siphonaptera) in Iran: Diversity, Host Range, and Medical Importance

Naseh Maleki-Ravasan, Samaneh Solhjouy-Fard, Jean-Claude Beaucournu, Anne Laudisoit, Ehsan Mostafavi

PLOS Neglected Tropical Diseases: published January 9, 2017 | https://doi.org/10.1371/journal.pntd.0005260

Phylogeography of Rift Valley Fever Virus in Africa and the Arabian Peninsula

Abdallah M. Samy, A. Townsend Peterson, Matthew Hall

PLOS Neglected Tropical Diseases: published January 9, 2017 | https://doi.org/10.1371/journal.pntd.0005226

Dengue in Latin America: Systematic Review of Molecular Epidemiological Trends

José Ramos-Castañeda, Flavia Barreto dos Santos, Ruth Martínez-Vega, Josélio Maria Galvão de Araujo, Graham Joint, Elsa Sarti

PLOS Neglected Tropical Diseases: published January 9, 2017 | https://doi.org/10.1371/journal.pntd.0005224

A Novel Human T-lymphotropic Virus Type 1c Molecular Variant in an Indigenous Individual from New Caledonia, Melanesia

Olivier Cassar, Françoise Charavay, Frédéric Touzain, Patricia Jeannin, Jean-Paul Grangeon, Sylvie Laumond, Eliane Chungue, Paul M. V. Martin, Antoine Gessain

PLOS Neglected Tropical Diseases: published January 6, 2017 | https://doi.org/10.1371/journal.pntd.0005278

Whole Genome Sequence Analysis of Salmonella Typhi Isolated in Thailand before and after the Introduction of a National Immunization Program

Zoe A. Dyson, Duy Pham Thanh, Ladaporn Bodhidatta, Carl Jeffries Mason, Apichai Srijan, Maia A. Rabaa, Phat Voong Vinh, Tuyen Ha Thanh, Guy E. Thwaites, Stephen Baker, Kathryn E. Holt

PLOS Neglected Tropical Diseases: published January 6, 2017 | https://doi.org/10.1371/journal.pntd.0005274

Transcriptome Sequencing Reveals Large-Scale Changes in Axenic Aedes aegypti Larvae

Kevin J. Vogel, Luca Valzania, Kerri L. Coon, Mark R. Brown, Michael R. Strand

PLOS Neglected Tropical Diseases: published January 6, 2017 | https://doi.org/10.1371/journal.pntd.0005273

The Antiviral RNAi Response in Vector and Non-vector Cells against Orthobunyaviruses

Isabelle Dietrich, Xiaohong Shi, Melanie McFarlane, Mick Watson, Anne-Lie Blomström, Jessica K. Skelton, Alain Kohl, Richard M. Elliott, Esther Schnettler

PLOS Neglected Tropical Diseases: published January 6, 2017 | https://doi.org/10.1371/journal.pntd.0005272

High Incidence of Human Rabies Exposure in Northwestern Tigray, Ethiopia: A Four-Year Retrospective Study

Gebreyohans Gebru Teklu, Teweldemedhn Gebretinsae Hailu, Gebremedhin Romha Eshetu

PLOS Neglected Tropical Diseases: published January 6, 2017 | https://doi.org/10.1371/journal.pntd.0005271

A Cohort Study of Adult Patients with Severe Dengue in Taiwanese Intensive Care Units: The Elderly and APTT Prolongation Matter for Prognosis

Chih-Cheng Hsieh, Cong-Tat Cia, Jen-Chieh Lee, Junne-Ming Sung, Nan-Yao Lee, Po-Lin Chen, Te-Hui Kuo, Jo-Yen Chao, Wen-Chien Ko

PLOS Neglected Tropical Diseases: published January 6, 2017 | https://doi.org/10.1371/journal.pntd.0005270

Assessing Ultrasonography as a Diagnostic Tool for Porcine Cysticercosis

Robert H. Flecker, Ian W. Pray, Saul J. Santivaňez, Viterbo Ayvar, Ricardo Gamboa, Claudio Muro, Luz Maria Moyano, Victor Benavides, Hector H. Garcia, Seth E. O’Neal

PLOS Neglected Tropical Diseases: published January 5, 2017 | https://doi.org/10.1371/journal.pntd.0005282

Do Two Screening Tools for Chikungunya Virus Infection that were Developed among Younger Population Work Equally as Well in Patients Aged over 65 Years?

Lidvine Godaert, Fatiha Najioullah, Lionel Bousquet, Thomas Malmontet, Benoît Fournet, Raymond Césaire, Jean-Luc Fanon, Moustapha Dramé

PLOS Neglected Tropical Diseases: published January 5, 2017 | https://doi.org/10.1371/journal.pntd.0005256

Prevalence of Chagas Disease in a U.S. Population of Latin American Immigrants with Conduction Abnormalities on Electrocardiogram

Mahmoud I. Traina, Salvador Hernandez, Daniel R. Sanchez, Jalal Dufani, Mohsin Salih, Adieb M. Abuhamidah, Wilman Olmedo, Jason S. Bradfield, Colin J. Forsyth, Sheba K. Meymandi

PLOS Neglected Tropical Diseases: published January 5, 2017 | https://doi.org/10.1371/journal.pntd.0005244

Predicting the Impact of Intervention Strategies for Sleeping Sickness in Two High-Endemicity Health Zones of the Democratic Republic of Congo

Kat S. Rock, Steve J. Torr, Crispin Lumbala, Matt J. Keeling

PLOS Neglected Tropical Diseases: published January 5, 2017 | https://doi.org/10.1371/journal.pntd.0005162

Comparison of Doxycycline, Minocycline, Doxycycline plus Albendazole and Albendazole Alone in Their Efficacy against Onchocerciasis in a Randomized, Open-Label, Pilot Trial

Ute Klarmann-Schulz, Sabine Specht, Alexander Yaw Debrah, Linda Batsa, Nana Kwame Ayisi-Boateng, Jubin Osei-Mensah, Yusif Mubarik, Peter Konadu, Arcangelo Ricchiuto, Rolf Fimmers, Sandra Arriens, Bettina Dubben, Louise Ford, Mark Taylor, Achim Hoerauf

PLOS Neglected Tropical Diseases: published January 5, 2017 | https://doi.org/10.1371/journal.pntd.0005156

A Systematic Review of the Incidence, Risk Factors and Case Fatality Rates of Invasive Nontyphoidal Salmonella (iNTS) Disease in Africa (1966 to 2014)

Ifeanyi Valentine Uche, Calman A. MacLennan, Allan Saul

PLOS Neglected Tropical Diseases: published January 5, 2017 | https://doi.org/10.1371/journal.pntd.0005118

A Double-Blind Randomized Controlled Trial of Maternal Postpartum Deworming to Improve Infant Weight Gain in the Peruvian Amazon

Layla S. Mofid, Martín Casapía, Eder Aguilar, Hermánn Silva, Antonio Montresor, Elham Rahme, William D. Fraser, Grace S. Marquis, Jozef Vercruysse, Lindsay H. Allen, Brittany Blouin, Hugo Razuri, Lidsky Pezo, Theresa W. Gyorkos

PLOS Neglected Tropical Diseases: published January 5, 2017 | https://doi.org/10.1371/journal.pntd.0005098

Comparison of Stable and Transient Wolbachia Infection Models in Aedes aegypti to Block Dengue and West Nile Viruses

Dirk Albert Joubert, Scott L. O’Neill

PLOS Neglected Tropical Diseases: published January 4, 2017 | https://doi.org/10.1371/journal.pntd.0005275

Health-Seeking Behaviour towards Poverty-Related Disease (PRDs): A Qualitative Study of People Living in Camps and on Campuses in Cameroon

Valerie Makoge, Harro Maat, Lenneke Vaandrager, Maria Koelen

PLOS Neglected Tropical Diseases: published January 4, 2017 | https://doi.org/10.1371/journal.pntd.0005218

Identifying Patient Perceived Barriers to Trichiasis Surgery in Kongwa District, Tanzania

Ryan J. Bickley, Harran Mkocha, Beatriz Munoz, Sheila West

PLOS Neglected Tropical Diseases: published January 4, 2017 | https://doi.org/10.1371/journal.pntd.0005211

Cyclobenzaprine Raises ROS Levels in Leishmania infantum and Reduces Parasite Burden in Infected Mice

Edézio Ferreira Cunha-Júnior, Valter Viana Andrade-Neto, Marta Lopes Lima, Thais Alves da Costa-Silva, Andres J. Galisteo Junior, Maria A. Abengózar, Coral Barbas, Luis Rivas, Elmo Eduardo Almeida-Amaral, Andre Gustavo Tempone, Eduardo Caio Torres-Santos

PLOS Neglected Tropical Diseases: published January 3, 2017 | https://doi.org/10.1371/journal.pntd.0005281

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Attachment of human neutrophils and monocytes to Brugia malayi microfilaria precedes parasite killing

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**Attachment of human neutrophils and monocytes to Brugia malayi microfilaria precedes parasite killing**