A preprint is a version of a scientific manuscript posted to a public server prior to peer review or formal publication in a scholarly journal. PLOS encourages authors to post preprints as a way to accelerate the dissemination of research.
PLOS and Preprint Servers
PLOS partners with Cold Spring Harbor Laboratory to make posting preprints in the life sciences easy and convenient. There are two ways to post:
- From bioRxiv or medRxiv to PLOS. Authors posting preprints to the bioRxiv or medRxiv preprint servers can choose to concurrently submit their manuscripts to relevant PLOS journal through the direct transfer to journal service.
- From PLOS to bioRxiv. Authors submitting manuscripts in the life sciences to PLOS Neglected Tropical Diseases may opt-in to post their work on bioRxiv during initial submission.
Preprints appear on bioRxiv in PDF format. Authors can choose to supply their own preprint PDF or use an automatically generated PDF.
If you supply a preprint PDF it will appear on bioRxiv exactly as it is.
Be sure to include title, authors, abstract, and the full text of the manuscript, along with any figures or tables, and their captions.
bioRxiv limits PDF file size to 20 MB or less. Be sure to compress your PDF to meet this requirement.
PLOS Neglected Tropical Diseases can automatically compile a preprint PDF suitable for bioRxiv from the manuscript file and figure files that are part of your regular journal submission. Supplementary information will not be included in auto-generated preprints, but may be uploaded directly to bioRxiv after posting.
PLOS Neglected Tropical Diseases screens preprint submissions for bioRxiv suitability upon submission and before the manuscript enters the peer review process. The screening involves checks for:
- Scope. Only submissions reporting primary research in biology and the life sciences are eligible for posting on bioRxiv. Read more about bioRxiv’s scope.
- Inappropriate, inflammatory, or offensive language or content
- Claims with implications for public health or other issues that should undergo peer review before posting
- Text overlap
- Dual use research of concern
- Copyright. The authors must have the right to post the full submission, including figures, under a CC BY license. Read more about licenses and copyright.
- Identifying personal information
Most preprints will appear on bioRxiv within a few days of submission. Authors will receive a notification of successful preprint posting directly from bioRxiv.
The journal office will communicate with the authors if issues arise or screening indicates a manuscript is not eligible for posting to bioRxiv.
Eligibility to post on bioRxiv is independent from the editorial assessment and peer review process. Preprint checks do not impact the decision regarding suitability for publication in PLOS Neglected Tropical Diseases. Read more about editorial selection at PLOS Neglected Tropical Diseases.
PLOS encourages editors to consider comments and feedback available on the preprint record to inform their editorial decision, and where relevant, editors may incorporate those comments in their editorial feedback to authors.
Once a manuscript has been posted as a preprint on bioRxiv, authors may submit updates or revisions on bioRxiv directly. Consult the bioRxiv submit page for specific instructions.
If a manuscript with a concurrent bioRxiv preprint is accepted for publication in PLOS Neglected Tropical Diseases, the preprint and published article will link to each other when the article appears online.
If a concern arises about a published PLOS article with a related bioRxiv preprint, PLOS will evaluate the concern according to our standard editorial processes, taking into account any relevant comments available on the bioRxiv preprint.