Confocal microscopy image showing the expression of serpin Wb123 (green) in microfilaria, accompanied by a collage of activated and inactivated brain macrophage images labelled with CFDA cell tracker (green) and displaying urokinase plasminogen activator expression (red). Upadhyay et al, 2025
Image Credit: Prince Upadhyay
Viewpoints
Mass treatment of tapeworms for Taenia solium eradication
PLOS Neglected Tropical Diseases: published December 3, 2025 | https://doi.org/10.1371/journal.pntd.0013762
Strengthening research and training on insecticide resistance in arthropod vectors in South America: The WINSA network
PLOS Neglected Tropical Diseases: published December 9, 2025 | https://doi.org/10.1371/journal.pntd.0013675
Body lice and scabies co-infestation among unsheltered migrants, refugees, and asylum seekers and the right to water and sanitation
PLOS Neglected Tropical Diseases: published December 10, 2025 | https://doi.org/10.1371/journal.pntd.0013807
Field notes: Children as WASH ambassadors—Insights from Pakistan’s trachoma elimination programme
PLOS Neglected Tropical Diseases: published December 12, 2025 | https://doi.org/10.1371/journal.pntd.0013769
Not here yet, but one bite away: Risk for vector-borne zoonotic diseases
PLOS Neglected Tropical Diseases: published December 15, 2025 | https://doi.org/10.1371/journal.pntd.0013802
Equitable access to essential medicines to treat neglected tropical diseases: Latest developments from the World Health Organization (WHO)
PLOS Neglected Tropical Diseases: published December 23, 2025 | https://doi.org/10.1371/journal.pntd.0013854
Policy Platform
An actionable roadmap for NTD morbidity, disability, and disfigurement management
PLOS Neglected Tropical Diseases: published December 8, 2025 | https://doi.org/10.1371/journal.pntd.0013760
Reviews
Laboratory diagnosis of melioidosis
PLOS Neglected Tropical Diseases: published December 4, 2025 | https://doi.org/10.1371/journal.pntd.0013761
Risk factors for emerging, re-emerging, and newly recognized arboviruses and zoonotic viruses in Brazilian amazon
PLOS Neglected Tropical Diseases: published December 23, 2025 | https://doi.org/10.1371/journal.pntd.0013735
Environmental changes and risk of plague epidemics in Indonesia
PLOS Neglected Tropical Diseases: published December 30, 2025 | https://doi.org/10.1371/journal.pntd.0013839
Research Articles
Assessing risks of dengue, chikungunya and Zika transmission associated to Aedes albopictus in Chania, Greece, 2017–2018
PLOS Neglected Tropical Diseases: published December 1, 2025 | https://doi.org/10.1371/journal.pntd.0013785
Community engagement in mass drug administration participatory interventions: A scoping review
PLOS Neglected Tropical Diseases: published December 1, 2025 | https://doi.org/10.1371/journal.pntd.0013737
Exploring drug coverage variability within districts: A CES approach to investigate treatment gaps in Mozambique’s schistosomiasis program
PLOS Neglected Tropical Diseases: published December 1, 2025 | https://doi.org/10.1371/journal.pntd.0013751
Anthropophagic Florida mosquito species are poor vectors of prototype and emerging strains of oropouche virus
PLOS Neglected Tropical Diseases: published December 1, 2025 | https://doi.org/10.1371/journal.pntd.0013755
Expression profiles of itch markers during scabies infection in a porcine scabies model
PLOS Neglected Tropical Diseases: published December 1, 2025 | https://doi.org/10.1371/journal.pntd.0013788
Schistosomiasis amongst adolescent boys in non-lakeshore southern Malawi: Investigating local risk-factors within a nested community-based cross-sectional survey
PLOS Neglected Tropical Diseases: published December 1, 2025 | https://doi.org/10.1371/journal.pntd.0013745
Therapeutic itineraries of children after snakebites in the Brazilian Amazon: A thematic drawing-and-story study
PLOS Neglected Tropical Diseases: published December 1, 2025 | https://doi.org/10.1371/journal.pntd.0013777
Two-leaves and many bites: Profiling dog-bites and adherence to rabies prophylaxis in tea-estate communities of Udalguri District, Assam, India
PLOS Neglected Tropical Diseases: published December 1, 2025 | https://doi.org/10.1371/journal.pntd.0013791
From neglected to notable: A growing public health challenge driven by hospitalization for sporotrichosis in Pernambuco, Northeast Brazil (2016–2024)
PLOS Neglected Tropical Diseases: published December 1, 2025 | https://doi.org/10.1371/journal.pntd.0013795
Cross-sectional assessment of Angiostrongylus cantonensis transmission risk mediated by invasive apple snails in Jiangsu province of China
PLOS Neglected Tropical Diseases: published December 2, 2025 | https://doi.org/10.1371/journal.pntd.0013803
Understanding the trends, clustering, and risk factors of pinworm infection in preschool settings: A repeated cross-sectional multi-center study between 2019 and 2024
PLOS Neglected Tropical Diseases: published December 2, 2025 | https://doi.org/10.1371/journal.pntd.0013800
Prevalence and risk factors associated with Taenia solium cysticercosis in pigs in Oyam district, Uganda
PLOS Neglected Tropical Diseases: published December 2, 2025 | https://doi.org/10.1371/journal.pntd.0013776
Analyzing first aid in textbooks used by non-medical and paramedical students in Nepal: A need of further attention for snakebite management!
PLOS Neglected Tropical Diseases: published December 2, 2025 | https://doi.org/10.1371/journal.pntd.0013765
Ultrasound-based population survey for abdominal cystic echinococcosis in Albania: Results from the NDTND project
PLOS Neglected Tropical Diseases: published December 2, 2025 | https://doi.org/10.1371/journal.pntd.0013784
Epidemiology and management of wildlife contacts in an emergency department of French Guiana
PLOS Neglected Tropical Diseases: published December 3, 2025 | https://doi.org/10.1371/journal.pntd.0013771
Semi-annual and annual mass drug administration of diethylcarbamazine and albendazole are equally effective regimens for eliminating lymphatic filariasis in Papua New Guinea
PLOS Neglected Tropical Diseases: published December 3, 2025 | https://doi.org/10.1371/journal.pntd.0012979
Multiepitope fusion protein-based ELISA for enhanced brucellosis serodiagnosis
PLOS Neglected Tropical Diseases: published December 3, 2025 | https://doi.org/10.1371/journal.pntd.0013804
Development of monoclonal antibodies against E1 protein of Chikungunya virus
PLOS Neglected Tropical Diseases: published December 4, 2025 | https://doi.org/10.1371/journal.pntd.0013794
Strokes following snakebite envenomations: A systematic review and individual patient data meta-analysis
PLOS Neglected Tropical Diseases: published December 4, 2025 | https://doi.org/10.1371/journal.pntd.0013789
Protective effects of clinical anticholinergic and anticholinesterase agents against Bungarus multicinctus venom and neurotoxin-rich snake venoms
PLOS Neglected Tropical Diseases: published December 4, 2025 | https://doi.org/10.1371/journal.pntd.0013759
Hiding in plain sight: Genomic and phenotypic characterization of mosquito-borne Bussuquara virus
PLOS Neglected Tropical Diseases: published December 5, 2025 | https://doi.org/10.1371/journal.pntd.0013774
Epidemiology and severity risk factors of dengue virus infection during the 2023-2024 outbreak in Colombia
PLOS Neglected Tropical Diseases: published December 5, 2025 | https://doi.org/10.1371/journal.pntd.0013115
Fostering empowerment: Transition from self-help groups to cooperatives in leprosy-affected communities in Nepal
PLOS Neglected Tropical Diseases: published December 5, 2025 | https://doi.org/10.1371/journal.pntd.0013799
The epidemiology and spatial distribution of Taenia solium taeniosis and cysticercosis in Kenya: The case of Busia County
PLOS Neglected Tropical Diseases: published December 5, 2025 | https://doi.org/10.1371/journal.pntd.0013746
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Proteomic profiles of Lissachatina (Heterobranchia) and Pomacea (Caenogastropoda) snails infected with Angiostrongylus cantonensis using 4D label-free quantitative analysis
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FC-duplex IgG1 (HTLV-1/2): Qualifying the flow cytometry IgG1 duplex assay for differential diagnosis of HTLV-1 and HTLV-2 infections
PLOS Neglected Tropical Diseases: published December 8, 2025 | https://doi.org/10.1371/journal.pntd.0013770
Rhodnius prolixus impairs Trypanosoma cruzi growth through cold-seeking behavioral thermoregulation
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Aspartic protease 2 from Trichinella spiralis excretion/secretion products hydrolyzes tight junctions of intestinal epithelial cells
PLOS Neglected Tropical Diseases: published December 8, 2025 | https://doi.org/10.1371/journal.pntd.0013805
Role of invasive Aedes (Aedimorphus) vittatus in chikungunya virus transmission in the newly-invaded coastal island city of Mombasa, Kenya
PLOS Neglected Tropical Diseases: published December 9, 2025 | https://doi.org/10.1371/journal.pntd.0013738
Calcineurin regulates morphological development, stress responses and virulence in Fonsecaea monophora
PLOS Neglected Tropical Diseases: published December 10, 2025 | https://doi.org/10.1371/journal.pntd.0013816
The diversity of sandflies (Psychodidae: Phlebotominae) and the presence of Leishmania spp. DNA in potential vectors of the Mbaracayú Forest Biosphere Reserve, Canindeyú, Paraguay: New records and findings
PLOS Neglected Tropical Diseases: published December 10, 2025 | https://doi.org/10.1371/journal.pntd.0013806
The phytochemical arbutin exerts potent anti-Toxoplasma effects through activation of cell-autonomous defense mechanisms while attenuating inflammation
PLOS Neglected Tropical Diseases: published December 11, 2025 | https://doi.org/10.1371/journal.pntd.0013815
Risk factors and control of Opisthorchis viverrini in the Lower Mekong Basin: A systematic review
PLOS Neglected Tropical Diseases: published December 11, 2025 | https://doi.org/10.1371/journal.pntd.0013790
Identifying gaps in the care and management of NTD morbidity, disability and disfigurement in Africa
PLOS Neglected Tropical Diseases: published December 11, 2025 | https://doi.org/10.1371/journal.pntd.0013834
Epidemiological baseline of Brucella spp. in South African wildlife
PLOS Neglected Tropical Diseases: published December 11, 2025 | https://doi.org/10.1371/journal.pntd.0013754
Enhancing Deinagkistrodon acutus antivenom potency through acutolysin A-targeted antibody supplementation
PLOS Neglected Tropical Diseases: published December 12, 2025 | https://doi.org/10.1371/journal.pntd.0013847
Improving Wolbachia-based control programs in urban settings: Insights from spatial modeling
PLOS Neglected Tropical Diseases: published December 12, 2025 | https://doi.org/10.1371/journal.pntd.0013787
Clinical presentation and management of snakebite envenoming in northern Ghana
PLOS Neglected Tropical Diseases: published December 12, 2025 | https://doi.org/10.1371/journal.pntd.0013820
Detection of Echinococcus granulosus sensu lato microRNAs in cystic echinococcosis patients: An exploratory study using quantitative PCR and digital PCR
PLOS Neglected Tropical Diseases: published December 15, 2025 | https://doi.org/10.1371/journal.pntd.0013833
Trends in injury hospitalisations due to contact with snakes in Australia, 2002 to 2020: A registry data analysis for the Australian Venomous Injuries Project (AVIP)
PLOS Neglected Tropical Diseases: published December 15, 2025 | https://doi.org/10.1371/journal.pntd.0013763
Intestinal immunopathological evaluation of mice reinfected with Trypanosoma cruzi Y strain
PLOS Neglected Tropical Diseases: published December 15, 2025 | https://doi.org/10.1371/journal.pntd.0013826
In vitro and in vivo efficacy of the antimycobacterial molecule SQ109 against the human pathogenic fungus, Cryptococcus neoformans
PLOS Neglected Tropical Diseases: published December 16, 2025 | https://doi.org/10.1371/journal.pntd.0013837
Seroprevalence and risk factors for Toxoplasma gondii infection in wild, domestic and companion animals in urban informal settlements from Salvador, Brazil
PLOS Neglected Tropical Diseases: published December 16, 2025 | https://doi.org/10.1371/journal.pntd.0013303
Community knowledge and response to Nipah virus infection and its transmission, prevention and control measures: Insights from a cross-sectional survey in Bangladesh
PLOS Neglected Tropical Diseases: published December 17, 2025 | https://doi.org/10.1371/journal.pntd.0013855
Prevalence, intensity, and risk factors of schistosomiasis and intestinal parasitic infections among primary school children in northern Uganda: Implications for public health interventions
PLOS Neglected Tropical Diseases: published December 17, 2025 | https://doi.org/10.1371/journal.pntd.0013827
Pilot study to assess the impact of feed-through insecticide on the sand fly density in an endemic area of zoonotic cutaneous leishmaniasis in Morocco
PLOS Neglected Tropical Diseases: published December 18, 2025 | https://doi.org/10.1371/journal.pntd.0013767
Transcriptomics analysis of in vivo Opisthorchis viverrini: Stage-specific gene expression and novel genes with stable expression in mammalian stages for opisthorchiasis intervention
PLOS Neglected Tropical Diseases: published December 18, 2025 | https://doi.org/10.1371/journal.pntd.0013714
A colorimetric method for detecting virulent bacteriophage to Vibrio cholerae in fecal and environmental samples
PLOS Neglected Tropical Diseases: published December 18, 2025 | https://doi.org/10.1371/journal.pntd.0013674
Drivers of rabies post-exposure prophylaxis noncompletion in Cambodia, 2019 to 2022
PLOS Neglected Tropical Diseases: published December 18, 2025 | https://doi.org/10.1371/journal.pntd.0013813
TPEDCC-PEG-based photodynamic therapy exhibits potent therapeutic efficacy against echinococcosis by inducing oxidative stress and mitochondria-mediated apoptosis
PLOS Neglected Tropical Diseases: published December 19, 2025 | https://doi.org/10.1371/journal.pntd.0013793
Functional dynamics between resident transcriptionally active microbes (TAMs) and host genes underlie Dengue severity
PLOS Neglected Tropical Diseases: published December 19, 2025 | https://doi.org/10.1371/journal.pntd.0013836
Spatiotemporal distribution and control of echinococcosis in Xinjiang, 2005–2023
PLOS Neglected Tropical Diseases: published December 19, 2025 | https://doi.org/10.1371/journal.pntd.0013775
Naringenin attenuates liver injury in Schistosoma mansoni-induced liver fibrosis and oxidative stress in mice model
PLOS Neglected Tropical Diseases: published December 19, 2025 | https://doi.org/10.1371/journal.pntd.0013825
Pre-hospital interventions in snakebite: A telephonic survey and follow up investigating snakebite envenoming from a tertiary care centre in Coastal Karnataka
PLOS Neglected Tropical Diseases: published December 19, 2025 | https://doi.org/10.1371/journal.pntd.0013334
Reversal of filarial serpin Wb123-urokinase plasminogen activator receptor mediated alternative macrophage activation by monoclonal antibody
PLOS Neglected Tropical Diseases: published December 22, 2025 | https://doi.org/10.1371/journal.pntd.0013726
Rebound in prevalence and intensity of Onchocerca volvulus infection five years after cessation of alternative treatment strategies in the Massangam Health District, West Region, Cameroon: need for coordinated and sustained efforts
PLOS Neglected Tropical Diseases: published December 22, 2025 | https://doi.org/10.1371/journal.pntd.0013849
Understanding the social determinants of Aedes-borne diseases in Iran: A qualitative exploration of challenges and policy solutions
PLOS Neglected Tropical Diseases: published December 22, 2025 | https://doi.org/10.1371/journal.pntd.0013850
Trichinella spiralis excretory-secretory proteins induced autophagy via activating AMPK/mTOR pathway and protected gut epithelial barrier
PLOS Neglected Tropical Diseases: published December 22, 2025 | https://doi.org/10.1371/journal.pntd.0013863
Insecticide resistance levels, spatial distribution, and kdr mutations in the dengue vector Aedes albopictus of Hong Kong
PLOS Neglected Tropical Diseases: published December 22, 2025 | https://doi.org/10.1371/journal.pntd.0013792
K-mer-based approach for serodiagnostic antigen discovery in Chagas disease using unassembled sequencing reads
PLOS Neglected Tropical Diseases: published December 22, 2025 | https://doi.org/10.1371/journal.pntd.0013835
Dairy farmers have minimal knowledge of bovine tuberculosis: A cross-sectional study in Bhutan
PLOS Neglected Tropical Diseases: published December 22, 2025 | https://doi.org/10.1371/journal.pntd.0013817
Failure of pyriproxyfen at recommended application frequency and doses to control Aedes mosquitoes in Thailand
PLOS Neglected Tropical Diseases: published December 22, 2025 | https://doi.org/10.1371/journal.pntd.0013042
Molecular detection of Histoplasma capsulatum in environmental samples collected from South African caves
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Complete genomes of Rickettsia typhi reveal a clonal population
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Correction: Schistosoma japonicum cathepsin L1: A potential target for anti-schistosomiasis strategies
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