Photomicrograph of a Trichuris egg from an archaeological deposit. Studying the epidemiology of helminth parasites during different historic periods helps us to understand factors that affect the changing relationship between humans and infectious disease. Ryan, Flammer, et al. (2022)
Image Credit: Patrik Flammer, Hannah Ryan and Adrian Smith (University of Oxford)
Review
Finding a chink in the armor: Update, limitations, and challenges toward successful antivirals against flaviviruses
PLOS Neglected Tropical Diseases: published April 28, 2022 | https://doi.org/10.1371/journal.pntd.0010291
Research Articles
Larval source reduction with a purpose: Designing and evaluating a household- and school-based intervention in coastal Kenya
PLOS Neglected Tropical Diseases: published April 1, 2022 | https://doi.org/10.1371/journal.pntd.0010199
A retrospective study on the socio-demographic factors and clinical parameters of dengue disease and their effects on the clinical course and recovery of the patients in a tertiary care hospital of Bangladesh
PLOS Neglected Tropical Diseases: published April 4, 2022 | https://doi.org/10.1371/journal.pntd.0010297
Diagnostic method-based underestimation of leptospirosis in clinical and research settings; an experience from a large prospective study in a high endemic setting
PLOS Neglected Tropical Diseases: published April 4, 2022 | https://doi.org/10.1371/journal.pntd.0010331
“Using the same hand”: The complex local perceptions of integrated one health based interventions in East Africa
PLOS Neglected Tropical Diseases: published April 4, 2022 | https://doi.org/10.1371/journal.pntd.0010298
Assessment of environmental contamination with soil-transmitted helminths life stages at school compounds, households and open markets in Jimma Town, Ethiopia
PLOS Neglected Tropical Diseases: published April 4, 2022 | https://doi.org/10.1371/journal.pntd.0010307
The effect of the sugar metabolism on Leishmania infantum promastigotes inside the gut of Lutzomyia longipalpis: A sweet relationship?
PLOS Neglected Tropical Diseases: published April 6, 2022 | https://doi.org/10.1371/journal.pntd.0010293
Smartphone multiplex microcapillary diagnostics using Cygnus: Development and evaluation of rapid serotype-specific NS1 detection with dengue patient samples
PLOS Neglected Tropical Diseases: published April 7, 2022 | https://doi.org/10.1371/journal.pntd.0010266
Incidence of lab-confirmed dengue fever in a pediatric cohort in Delhi, India
PLOS Neglected Tropical Diseases: published April 7, 2022 | https://doi.org/10.1371/journal.pntd.0010333
Community-level trachoma ecological associations and the use of geospatial analysis methods: A systematic review
PLOS Neglected Tropical Diseases: published April 8, 2022 | https://doi.org/10.1371/journal.pntd.0010272
Extensive public health initiatives drive the elimination of Aedes aegypti (Diptera, Culicidae) from a town in regional Queensland: A case study from Gin Gin, Australia
PLOS Neglected Tropical Diseases: published April 8, 2022 | https://doi.org/10.1371/journal.pntd.0010243
Comparison of PvLAP5 and Pvs25 qRT-PCR assays for the detection of Plasmodium vivax gametocytes in field samples preserved at ambient temperature from remote malaria endemic regions of Panama
PLOS Neglected Tropical Diseases: published April 8, 2022 | https://doi.org/10.1371/journal.pntd.0010327
Two-stage lot quality assurance sampling framework for monitoring and evaluation of neglected tropical diseases, allowing for imperfect diagnostics and spatial heterogeneity
PLOS Neglected Tropical Diseases: published April 8, 2022 | https://doi.org/10.1371/journal.pntd.0010353
The life experience of leprosy families in maintaining interaction patterns in the family to support healing in leprosy patients in Indonesian society. A phenomenological qualitative study
PLOS Neglected Tropical Diseases: published April 8, 2022 | https://doi.org/10.1371/journal.pntd.0010264
Rainfall and other meteorological factors as drivers of urban transmission of leptospirosis
PLOS Neglected Tropical Diseases: published April 11, 2022 | https://doi.org/10.1371/journal.pntd.0007507
Prevalence and factors associated with human Taenia solium taeniosis and cysticercosis in twelve remote villages of Ranomafana rainforest, Madagascar
PLOS Neglected Tropical Diseases: published April 11, 2022 | https://doi.org/10.1371/journal.pntd.0010265
Determination of the trend of incidence of cutaneous leishmaniasis in Kerman province 2014-2020 and forecasting until 2023. A time series study
PLOS Neglected Tropical Diseases: published April 11, 2022 | https://doi.org/10.1371/journal.pntd.0010250
Evaluating sampling strategies for enzootic Venezuelan equine encephalitis virus vectors in Florida and Panama
PLOS Neglected Tropical Diseases: published April 13, 2022 | https://doi.org/10.1371/journal.pntd.0010329
Systematic identification and characterization of long noncoding RNAs (lncRNAs) during Aedes albopictus development
PLOS Neglected Tropical Diseases: published April 13, 2022 | https://doi.org/10.1371/journal.pntd.0010245
In silico analyses of penicillin binding proteins in Burkholderia pseudomallei uncovers SNPs with utility for phylogeography, species differentiation, and sequence typing
PLOS Neglected Tropical Diseases: published April 13, 2022 | https://doi.org/10.1371/journal.pntd.0009882
Analytical sensitivity and clinical performance of "COVID-19 RT-PCR Real TM FAST (CY5) (ATGen, Uruguay) and "ECUGEN SARS-CoV-2 RT-qPCR" (UDLA-STARNEWCORP, Ecuador)": High quality-low cost local SARS-CoV-2 tests for South America
PLOS Neglected Tropical Diseases: published April 13, 2022 | https://doi.org/10.1371/journal.pntd.0010082
Experimental Schistosoma japonicum-induced pulmonary hypertension
PLOS Neglected Tropical Diseases: published April 13, 2022 | https://doi.org/10.1371/journal.pntd.0010343
Sex-specific distribution and classification of Wolbachia infections and mitochondrial DNA haplogroups in Aedes albopictus from the Indo-Pacific
PLOS Neglected Tropical Diseases: published April 13, 2022 | https://doi.org/10.1371/journal.pntd.0010139
Circulating IL-6, IL-10, and TNF-alpha and IL-10/IL-6 and IL-10/TNF-alpha ratio profiles of polyparasitized individuals in rural and urban areas of gabon
PLOS Neglected Tropical Diseases: published April 14, 2022 | https://doi.org/10.1371/journal.pntd.0010308
Two-year death prediction models among patients with Chagas Disease using machine learning-based methods
PLOS Neglected Tropical Diseases: published April 14, 2022 | https://doi.org/10.1371/journal.pntd.0010356
Mosquito survey in Mauritania: Detection of Rift Valley fever virus and dengue virus and the determination of feeding patterns
PLOS Neglected Tropical Diseases: published April 15, 2022 | https://doi.org/10.1371/journal.pntd.0010203
“One feels anger to know there is no one to help us!”. Perceptions of mothers of children with Zika virus-associated microcephaly in Caribbean Colombia: A qualitative study
PLOS Neglected Tropical Diseases: published April 18, 2022 | https://doi.org/10.1371/journal.pntd.0010328
A national survey integrating clinical, laboratory, and WASH data to determine the typology of trachoma in Nauru
PLOS Neglected Tropical Diseases: published April 19, 2022 | https://doi.org/10.1371/journal.pntd.0010275
Optimizing one-dose and two-dose cholera vaccine allocation in outbreak settings: A modeling study
PLOS Neglected Tropical Diseases: published April 20, 2022 | https://doi.org/10.1371/journal.pntd.0010358
Prevalence and risk factors of urogenital schistosomiasis among under-fives in Mtama District in the Lindi region of Tanzania
PLOS Neglected Tropical Diseases: published April 20, 2022 | https://doi.org/10.1371/journal.pntd.0010381
Aedes aegypti abundance and insecticide resistance profiles in the Applying Wolbachia to Eliminate Dengue trial
PLOS Neglected Tropical Diseases: published April 20, 2022 | https://doi.org/10.1371/journal.pntd.0010284
Transplacental Zika virus transmission in ex vivo perfused human placentas
PLOS Neglected Tropical Diseases: published April 20, 2022 | https://doi.org/10.1371/journal.pntd.0010359
Diverse and atypical manifestations of Q fever in a metropolitan city hospital: Emerging role of next-generation sequencing for laboratory diagnosis of Coxiella burnetii
PLOS Neglected Tropical Diseases: published April 20, 2022 | https://doi.org/10.1371/journal.pntd.0010364
Contextualizing mobility during the Ebola epidemic in Liberia
PLOS Neglected Tropical Diseases: published April 20, 2022 | https://doi.org/10.1371/journal.pntd.0010370
A longitudinal two-year survey of the prevalence of trypanosomes in domestic cattle in Ghana by massively parallel sequencing of barcoded amplicons
PLOS Neglected Tropical Diseases: published April 20, 2022 | https://doi.org/10.1371/journal.pntd.0010300
Reconstructing the history of helminth prevalence in the UK
PLOS Neglected Tropical Diseases: published April 21, 2022 | https://doi.org/10.1371/journal.pntd.0010312
Black flies and Onchocerciasis: Knowledge, attitude and practices among inhabitants of Alabameta, Osun State, Southwestern, Nigeria
PLOS Neglected Tropical Diseases: published April 21, 2022 | https://doi.org/10.1371/journal.pntd.0010320
Pathological and immunological evaluation of different regimens of praziquantel treatment in a mouse model of Schistosoma mansoni infection
PLOS Neglected Tropical Diseases: published April 21, 2022 | https://doi.org/10.1371/journal.pntd.0010382
Conserved metabolic enzymes as vaccine antigens for giardiasis
PLOS Neglected Tropical Diseases: published April 25, 2022 | https://doi.org/10.1371/journal.pntd.0010323
Delayed correlation between the incidence rate of indigenous murine typhus in humans and the seropositive rate of Rickettsia typhi infection in small mammals in Taiwan from 2007–2019
PLOS Neglected Tropical Diseases: published April 25, 2022 | https://doi.org/10.1371/journal.pntd.0010394
Identification of asymptomatic Entamoeba histolytica infection by a serological screening test: A cross-sectional study of an HIV-negative men who have sex with men cohort in Japan
PLOS Neglected Tropical Diseases: published April 25, 2022 | https://doi.org/10.1371/journal.pntd.0009793
Anti-Th17 and anti-Th2 responses effects of hydro-ethanolic extracts of Aframomum melegueta, Khaya senegalensis and Xylopia aethiopica in hyperreactive onchocerciasis individuals’ peripheral blood mononuclear cells
PLOS Neglected Tropical Diseases: published April 25, 2022 | https://doi.org/10.1371/journal.pntd.0010341
Berbamine hydrochloride potently inhibits SARS-CoV-2 infection by blocking S protein-mediated membrane fusion
PLOS Neglected Tropical Diseases: published April 25, 2022 | https://doi.org/10.1371/journal.pntd.0010363
Infection intensity-dependent accuracy of reagent strip for the diagnosis of Schistosoma haematobium and estimation of treatment prevalence thresholds
PLOS Neglected Tropical Diseases: published April 25, 2022 | https://doi.org/10.1371/journal.pntd.0010332
Pilot trial using mass field-releases of sterile males produced with the incompatible and sterile insect techniques as part of integrated Aedes aegypti control in Mexico
PLOS Neglected Tropical Diseases: published April 26, 2022 | https://doi.org/10.1371/journal.pntd.0010324
Effect of a single dose of 8 mg moxidectin or 150 μg/kg ivermectin on O. volvulus skin microfilariae in a randomized trial: Differences between areas in the Democratic Republic of the Congo, Liberia and Ghana and impact of intensity of infection
PLOS Neglected Tropical Diseases: published April 27, 2022 | https://doi.org/10.1371/journal.pntd.0010079
Prevalence of Strongyloides stercoralis infection and associated clinical symptoms among schoolchildren living in different altitudes of Amhara National Regional State, northwest Ethiopia
PLOS Neglected Tropical Diseases: published April 28, 2022 | https://doi.org/10.1371/journal.pntd.0010299
COX-2 is required to mediate crosstalk of ROS-dependent activation of MAPK/NF-κB signaling with pro-inflammatory response and defense-related NO enhancement during challenge of macrophage-like cell line with Giardia duodenalis
PLOS Neglected Tropical Diseases: published April 28, 2022 | https://doi.org/10.1371/journal.pntd.0010402
Clinical characteristics and risk factors for severe scrub typhus in pediatric and elderly patients
PLOS Neglected Tropical Diseases: published April 29, 2022 | https://doi.org/10.1371/journal.pntd.0010357
Fifty years of struggle to control cutaneous leishmaniasis in the highest endemic county in Iran: A longitudinal observation inferred with interrupted time series model
PLOS Neglected Tropical Diseases: published April 29, 2022 | https://doi.org/10.1371/journal.pntd.0010271
Ultrasonography as a diagnostic tool for Neural Pain in Leprosy
PLOS Neglected Tropical Diseases: published April 29, 2022 | https://doi.org/10.1371/journal.pntd.0010393
Human Seroprevalence for Dengue, Ross River, and Barmah Forest viruses in Australia and the Pacific: A systematic review spanning seven decades
PLOS Neglected Tropical Diseases: published April 29, 2022 | https://doi.org/10.1371/journal.pntd.0010314
Molecular epidemiology of scrub typhus in Taiwan during 2006–2016
PLOS Neglected Tropical Diseases: published April 29, 2022 | https://doi.org/10.1371/journal.pntd.0010369
Exposure to multiple pathogens - serological evidence for Rift Valley fever virus, Coxiella burnetii, Bluetongue virus and Brucella spp. in cattle, sheep and goat in Mali
PLOS Neglected Tropical Diseases: published April 29, 2022 | https://doi.org/10.1371/journal.pntd.0010342
Corrections
Correction: A spatio-temporal approach to short-term prediction of visceral leishmaniasis diagnoses in India
PLOS Neglected Tropical Diseases: published April 4, 2022 | https://doi.org/10.1371/journal.pntd.0010346
Related Articles
Correction: Laboratory demonstration of the vertical transmission of Rift Valley fever virus by Culex tarsalis mosquitoes
PLOS Neglected Tropical Diseases: published April 26, 2022 | https://doi.org/10.1371/journal.pntd.0010413
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Formal Comment
A critical appraisal of the ENLIST severity scale for erythema nodosum leprosum
PLOS Neglected Tropical Diseases: published April 26, 2022 | https://doi.org/10.1371/journal.pntd.0010378