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November 2024

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The development of low-cost novel diagnostic techniques based on the detection and identification of S. haematobium eggs in urine by AI tools would be a suitable alternative to conventional microscopy in non-endemic settings. This technical proof-of-principle study from Maturana et al allows laying the basis for improving the system, and optimizing its implementation in the laboratories.

Image Credit: Maturana et al. 2024

Policy Platform

A pathway for skin NTD diagnostic development

Michael Marks, Sundeep Chaitanya Vedithi, Wendy W. J. van de Sande, Bruno Levecke, Anthony W. Solomon, Kingsley Asiedu, Camilla L. Ducker, Patrick Lammie, Daniel Argaw Dagne, Isra Cruz, on behalf of the WHO Diagnostic Technical Advisory Group on Neglected Tropical Diseases

Review

Keratoplasty to restore vision in trachomatous corneal opacity: A literature review

Iain Davidson, Matthew J. Burton, Noopur Gupta, Amir B. Kello, Jennifer Rose-Nussbaumer, Anthony W. Solomon

Research Articles

Association of the humoral immune response with the inflammatory profile in Plasmodium vivax infections in pregnant women

Rodrigo Medeiros de Souza, Maria Inês dos Santos, Laura Cordeiro Gomes, Bruna Beatriz Pedroza de Melo, Erika Paula Machado Separovic, Oscar Murillo, Gerhard Wunderlich, Taane Gregory Clark, Susana Campino, Sabrina Epiphanio, Claudio Romero Farias Marinho, Jamille Gregório Dombrowski

Variable effects of transient Wolbachia infections on alphaviruses in Aedes aegypti

Brittany L. Dodson, Sujit Pujhari, Marco Brustolin, Hillery C. Metz, Jason L. Rasgon

The role of connectivity on malaria dynamics across areas with contrasting control coverage in the Peruvian Amazon

Gabriel Carrasco-Escobar, Diego Villa, Antony Barja, Rachel Lowe, Alejandro Llanos-Cuentas, Tarik Benmarhnia

Mapping schistosomiasis risk landscapes and implications for disease control: A case study for low endemic areas in the Middle Paranapanema river basin, São Paulo, Brazil

Vivian Alessandra Ferreira da Silva, Milton Kampel, Rafael Silva dos Anjos, Raquel Gardini Sanches Palasio, Maria Isabel Sobral Escada, Roseli Tuan, Alyson Singleton, Caroline Kate Glidden, Andrew Chamberlin, Giulio Alessandro De Leo, Adriano Pinter dos Santos, Antônio Miguel Vieira Monteiro

Phenotypic and molecular characterization of Prototheca wickerhamii from a Brazilian case of human systemic protothecosis

Luciana Duarte-Silva, Raquel Vilela, Isabela A. Rodrigues, Vanessa C. R. Magalhães, Marcelo V. Caliari, Leonel Mendoza, Adriana Oliveira Costa

The gut microbiota is essential for Trichinella spiralis—evoked suppression of colitis

Hualei Sun, Shao Rong Long, Miao Jiang, Hui Ran Zhang, Jing Jing Wang, Zi Xuan Liao, Jing Cui, Zhong Quan Wang

Spatiotemporal distribution and meteorological factors of hemorrhagic fever with renal syndrome in Hubei province

Hang Li, Rui Yang, Xuhua Guan, Xiaobo Huang, Honglin Jiang, Liangfei Tan, Jinfeng Xiong, Mingjun Peng, Tianbao Zhang, Xuan Yao

A single dose recombinant AAV based CHIKV vaccine elicits robust and durable protective antibody responses in mice

Qin-Xuan Zhu, Ya-Nan Zhang, Hong-Qing Zhang, Chao Leng, Cheng-Lin Deng, Xin Wang, Jia-Jia Li, Xiang-Li Ye, Bo Zhang, Xiao-Dan Li

Snake phobia among the general population of Tamil Nadu, India

Anika Salim, Gnaneswar Chandrasekharuni, José R. Almeida, Rajendran Vaiyapuri, Harry F. Williams, Sundhararajan Arumugam, Subramanian Senthilkumaran, Ketan Patel, Timothy Williams, András Norbert Zsidó, Sakthivel Vaiyapuri

Development of an automated artificial intelligence-based system for urogenital schistosomiasis diagnosis using digital image analysis techniques and a robotized microscope

Carles Rubio Maturana, Allisson Dantas de Oliveira, Francesc Zarzuela, Edurne Ruiz, Elena Sulleiro, Alejandro Mediavilla, Patricia Martínez-Vallejo, Sergi Nadal, Tomàs Pumarola, Daniel López-Codina, Alberto Abelló, Elisa Sayrol, Joan Joseph-Munné

Buruli ulcer surveillance in south-eastern Australian possums: Infection status, lesion mapping and internal distribution of Mycobacterium ulcerans

Emma C. Hobbs, Jessica L. Porter, Jean Y. H. Lee, Panayiotis Loukopoulos, Pam Whiteley, Lee F. Skerratt, Timothy P. Stinear, Katherine B. Gibney, Anna L. Meredith

Oro-facial filariasis–A systematic review of the literature

Agnesa Bytyqi, Chiara Karas, Klara Pechmann, Michael Ramharter, Johannes Mischlinger

The effects of seasonal human mobility and Aedes aegypti habitat suitability on Zika virus epidemic severity in Colombia

Brandon Lieberthal, Brian Allan, Sandra De Urioste-Stone, Andrew Mackay, Aiman Soliman, Shaowen Wang, Allison M. Gardner

First evidence of circulation of multiple arboviruses in Algeria

Saïd C. Boubidi, Laurence Mousson, Tahar Kernif, Fayez Khardine, Aïssam Hachid, Cécile Beck, Sylvie Lecollinet, Rayane A. Moraes, Sara Moutailler, Catherine Dauga, Anna Bella Failloux

Heart function enhancement by an Nrf2-activating antioxidant in acute Y-strain Chagas disease, but not in chronic Colombian or Y-strain

Hilton Antônio Mata-Santos, Camila Victória Sousa Oliveira, Daniel F. Feijo, Daniel Figueiredo Vanzan, Glaucia Vilar-Pereira, Isalira P. Ramos, Vitor Coutinho Carneiro, Oscar Moreno-Loaiza, Jaline Coutinho Silverio, Joseli Lannes-Vieira, Emiliano Medei, Marcelo T. Bozza, Claudia N. Paiva

Clinical anemia predicts dermal parasitism and reservoir infectiousness during progressive visceral leishmaniosis

Max C. Waugh, Karen I. Cyndari, Tom J. Lynch, Soomin Koh, Ferney Henao-Ceballos, Jacob J. Oleson, Paul M. Kaye, Christine A. Petersen

Mycetoma: A critical appraisal of educational content on YouTube

Ivaan Pitua, Raafidha Raizudheen, Amelia Margaret Namiiro, Lorraine Apili, Felix Bongomin

Clonorchis sinensis infection contributes to hepatocellular carcinoma progression via enhancing angiogenesis

Caibiao Wei, Junxian Chen, Qiuhai Yu, Yuling Qin, Taijun Huang, Fengfei Liu, Xiaolan Pan, Qiumei Lin, Zeli Tang, Min Fang

Using community-based participatory approaches to improve access to mass drug administration for trachoma elimination in a pastoral conflict area of Kenya

Paul M. Gichuki, Bridget W. Kimani, Tabitha Kanyui, Collins Okoyo, Titus Watitu, Wyckliff P. Omondi, Doris W. Njomo

Accuracy of immunological tests on serum and urine for diagnosis of Taenia solium neurocysticercosis: A systematic review

Lisa Van Acker, Luz Toribio, Mkunde Chachage, Hang Zeng, Brecht Devleesschauwer, Héctor H. Garcia, Sarah Gabriël, on behalf of the NeuroSolve Consortium

Giardia lamblia risk factors and burden in children with acute gastroenteritis in a Nicaraguan birth cohort

Lester Gutiérrez, Nadja A. Vielot, Roberto Herrera, Yaoska Reyes, Christian Toval-Ruíz, Patricia Blandón, Rebecca J. Rubinstein, Javier Mora, Luther A. Bartelt, Filemón Bucardo, Sylvia Becker-Dreps, Samuel Vilchez

Photodynamic inactivation strategies for maximizing antifungal effect against Sporothrix spp. and Candida albicans in an in vitro investigation

Amanda Regina Rocha, Natalia Mayumi Inada, Ana Paula da Silva, Vanderlei Salvador Bagnato, Hilde Harb Buzzá

Perioperative outcomes and hospitalization costs of radical vs. conservative surgery for hepatic cystic echinococcosis: A retrospective study

Honggang Shi, Kahaer Tuerxun, Aizizaimu Yusupu, Zainuer Yusupu, Qilin Xu, Yibin Jia, Musitaba Maimaitireyimu, Tuerhongaji Maimaitiaili, Muzaipaer Muhetajiang, Jiaxin Lin, Chengmin Ma, Xiaofeng Li, Yuanquan Wu, Yonghui Su

Multilocus sequence typing of clinical Burkholderia pseudomallei isolates from Cambodia

Emmanuel Gyamfi, Gauthier Delvallez, Sokleaph Cheng, Soda Meng, Kimyeun Oeurn, Chanchakriya Sam, Alexandra Kerleguer, Bertrand Guillard, Anne-Laure Bañuls, Mallorie Hide

Serological evidence of natural exposure to rabies in rural populations in Gabon

Linda Bohou Kombila, Nadine N’dilimabaka, Julien Lannoy, Eric Elguero, Eric M. Leroy, Laurent Dacheux, Pierre Becquart

Assessing the ecological patterns of Aedes aegypti in areas with high arboviral risks in the large city of Abidjan, Côte d’Ivoire

Claver N. Adjobi, Julien Z. B. Zahouli, Négnorogo Guindo-Coulibaly, Allassane F. Ouattara, Laura Vavassori, Maurice A. Adja

Circulating extracellular vesicles in sera of chronic patients as a method for determining active parasitism in Chagas disease

Noelia Lozano, Alexa Prescilla-Ledezma, Eva Calabuig, Maria Trelis, José Miguel Sahuquillo Arce, José Luis López Hontangas, Luis Miguel de Pablos, Mercedes Gomez-Samblas, Antonio Osuna

Genomic epidemiology and phenotypic characterisation of Salmonella enterica serovar Panama in Victoria, Australia

Samriddhi Thakur, Sarah L. Baines, Cheryll M. Sia, Mary Valcanis, Louise M. Judd, Benjamin P. Howden, Hayley J. Newton, Danielle J. Ingle

Spatial and temporal modeling of the global burden of Cutaneous Leishmaniasis in Brazil: A 21-year ecological study

Erica Santos dos Reis, Wandklebson Silva Paz, Rosália Elen Santos Ramos, Caíque Jordan Nunes Ribeiro, Laiza Santos Biano, Márcio Bezerra-Santos, Camila Indiani de Oliveira, Michael Wheeler Lipscomb, Tatiana Rodrigues de Moura

Serovars, virulence factors, and antimicrobial resistance profile of non-typhoidal Salmonella in the human-dairy interface in Northwest Ethiopia: A one health approach

Achenef Melaku Beyene, Yismaw Alemie, Mucheye Gizachew, Ahmed E. Yousef, Bereket Dessalegn, Abebe Belete Bitew, Amare Alemu, Waktole Gobena, Kornschober Christian, Baye Gelaw

Understanding the factors contributing to dengue virus and chikungunya virus seropositivity and seroconversion among children in Kenya

Amna Tariq, Aslam Khan, Francis Mutuku, Bryson Ndenga, Donal Bisanzio, Elysse N. Grossi-Soyster, Zainab Jembe, Priscilla Maina, Philip Chebii, Charles Ronga, Victoria Okuta, Angelle Desiree LaBeaud

Development of a seroepidemiological tool for bat-borne and shrew-borne hantaviruses and its application using samples from Zambia

Rakiiya Sikatarii Sarii, Masahiro Kajihara, Zuoxing Wei, Sithumini M. W. Lokpathirage, Devinda S. Muthusinghe, Akina Mori-Kajihara, Katendi Changula, Yongjin Qiu, Joseph Ndebe, Bernard M. Hang’ombe, Fuka Kikuchi, Ai Hayashi, Motoi Suzuki, Hajime Kamiya, Satoru Arai, Ayato Takada, Kumiko Yoshimatsu

Knowledge, Perceptions, Challenges and opportunities in achieving sustainable coverage of mass drug administration towards the control and elimination of Schistosomiasis and Soil Transmitted Helminths in hard-to-reach communities of Ghana

Akua Obeng Forson, Patrick F. Ayeh-Kumi, Abdul Rahim Mohammed, Isaac Kwame Sraku, Gustavus Adolphus Myers-Hansen, Yaw Asare Afrane

Impact of climate and land use on the temporal variability of sand fly density in Sri Lanka: A 2-year longitudinal study

Sanath C. Senanayake, Prasad Liyanage, Dulani R. K. Pathirage, M. F. Raushan Siraj, B. G. D. Nissanka Kolitha De Silva, Nadira D. Karunaweera

The cost of sleeping sickness vector control in Yasa Bonga, a health district in the Democratic Republic of the Congo

Rian Snijders, Alexandra P. M. Shaw, Richard Selby, Inaki Tirados, Paul R. Bessell, Alain Fukinsia, Erick Miaka, Fabrizio Tediosi, Epco Hasker, Marina Antillon

Comparing microbiological and molecular diagnostic tools for the surveillance of anthrax

Sunday Ochonu Ochai, Ayesha Hassim, Edgar H. Dekker, Thuto Magome, Kgaugelo Edward Lekota, S. Marcus Makgabo, Lin-Mari de Klerk-Loris, Louis O. van Schalkwyk, Pauline L. Kamath, Wendy C. Turner, Henriette van Heerden

Molecular identification of tick-borne Rickettsia, Anaplasma, Ehrlichia, Babesia, and Colpodella in confiscated Malayan pangolins

Bing Li, Jun-Qiong Zhai, Ya-Jiang Wu, Fen Shan, Jie-Jian Zou, Fang-Hui Hou, Teng-Cheng Que, Wu Chen

Long-term visual outcomes and histopathologic findings after cataract surgery in Ebola virus disease survivors in the Ebola virus RNA persistence in ocular tissues and fluids (EVICT) study

Caleb D. Hartley, Lucas Kim, Tolulope Fashina, Jack Begley, John G. Mattia, Matthew J. Vandy, Lloyd C. Harrison-Williams, Jalikatu Mustapha, Robert F. Garry, John S. Schieffelin, Donald S. Grant, Augustine Goba, Colleen S. Kraft, Brent R. Hayek, Gustavo Palacios, Jessica Shantha, Ian Crozier, Xiankun Zeng, Steven Yeh, Ebola Virus Persistence in Ocular Tissues and Fluids (EVICT) Study Investigators

Clinical and laboratory comparison of severe (Group B and C) Dengue cases with molecular characterization from 2019 epidemics in Dhaka, Bangladesh

Fazle Rabbi Chowdhury, Zazeba Hossain, Nahid Parvez, Forhad Uddin Hasan Chowdhury, Mohammad Anwarul Bari, Sudip Ranjan Deb, Mustak Ibn Ayub, Md Uzzwal Mallik, Sakib Aman, Mohammad Ahsanul Haque, Md Arman Hossain, Murada Alam, Muhammad Kamrul Islam, Md Mujibur Rahman

The impact of COVID-19 mobility restrictions on dengue transmission in urban areas

Jorge L. B. Araújo, Rafael Bomfim, Cesar I. N. Sampaio Filho, Luciano P. G. Cavalcanti, Antonio S. Lima Neto, José S. Andrade Jr., Vasco Furtado

Forecasting the relative abundance of Aedes vector populations to enhance situational awareness for mosquito control operations

Paulo C. Ventura, Allisandra G. Kummer, André B. B. Wilke, Jagadeesh Chitturi, Megan D. Hill, Chalmers Vasquez, Isik Unlu, John-Paul Mutebi, Susanne Kluh, Steve Vetrone, Dan Damian, John Townsend, Maria Litvinova, Marco Ajelli

Prevalence and intensity of Schistosoma mansoni infection, and contributing factors in Alamata district of Tigray Region, Northern Ethiopia

Gessessew Bugssa, Tilahun Teklehaymanot, Girmay Medhin, Nega Berhe

Influence of angiotensin II type 1 receptors and angiotensin-converting enzyme I/D gene polymorphisms on the progression of Chagas’ heart disease in a Brazilian cohort: Impact of therapy on clinical outcomes

Thayse do Espírito Santo Protásio da Silva, Lucia Elena Alvarado-Arnez, Angelica Martins Batista, Silvia Marinho Martins Alves, Gloria Melo, Cristina Veloso Carrazzone, Isabelle de Oliveira Moraes, Antonio G. Pacheco, Camila Sarteschi, Milton Ozório Moraes, Wilson Oliveira Jr, Joseli Lannes-Vieira

Genetic differentiation of Oncomelania hupensis robertsoni in hilly regions of China: Using the complete mitochondrial genome

Jing Song, Hongqiong Wang, Shizhu Li, Peijun Qian, Wenya Wang, Meifen Shen, Zongya Zhang, Jihua Zhou, Chunying Li, Zaogai Yang, Yuwan Hao, Chunhong Du, Yi Dong

Efficacy and safety of albendazole alone versus albendazole in combination with ivermectin for the treatment of Trichuris trichiura infections: An open-label, randomized controlled superiority trial in south-western Uganda

Marta Sólveig Palmeirim, Eveline Hürlimann, Prudence Beinamaryo, Hilda Kyarisiima, Betty Nabatte, Jan Hattendorf, Peter Steinmann, Jennifer Keiser

Quantitative modelling for dengue and Aedes mosquitoes in Africa: A systematic review of current approaches and future directions for Early Warning System development

Lembris Laanyuni Njotto, Wilfred Senyoni, Ottmar Cronie, Michael Alifrangis, Anna-Sofie Stensgaard

Burden and risk factors of suspected cholangiocarcinoma in high Opisthorchis viverrini endemic rural communities in southern Lao PDR

Anousin Homsana, Phonesavanh Southisavath, Kerstin Kling, Jan Hattendorf, Savina Vorasane, Daniel Henry Paris, Nicole Probst-Hensch, Somphou Sayasone, Peter Odermatt

Role of neutrophils in the pathogenesis of Post Kala-azar Dermal Leishmaniasis (PKDL)

Madhurima Roy, Ritika Sengupta, Bidhan Chandra Chakraborty, Uttara Chatterjee, Esther von Stebut, Paul M. Kaye, Mitali Chatterjee

Vision guides the twilight search for oviposition sites of the Asian tiger mosquito, Aedes albopictus

Si Yu Zhao, Hong Kai Liu, Zhen Sheng Xie, Yi Ming Wu, Pei Lin Wu, Tong Liu, Wen Qiang Yang, Jing Wu, JunYu Fu, Chun Mei Wang, Anthony A. James, Xiao-Guang Chen

Formal Comment

Comment on: Target-based discovery of a broad-spectrum flukicide

Timir Tripathi