Field evaluation of a portable artificial intelligence–powered digital pathology (AI DP) platform for the detection of soil transmitted helminths and intestinal schistosomiasis in a zero infrastructure rural setting. Local technicians compare results from AI assisted slide scanners with conventional microscopy during research activities assessing the platform’s performance for program monitoring. Ward et al, 2026.
Image Credit: Photo by Peter K. Ward / AI4NTD Consortium.
Viewpoints
Tuberculosis control in Ethiopian prisons: A forgotten front in the end TB Strategy
PLOS Neglected Tropical Diseases: published March 4, 2026 | https://doi.org/10.1371/journal.pntd.0014048
Adapting lessons from the Indian subcontinent to accelerate elimination of visceral leishmaniasis as a public health problem in East Africa
PLOS Neglected Tropical Diseases: published March 13, 2026 | https://doi.org/10.1371/journal.pntd.0014088
Reviews
Epidemiology and clinical spectrum of leishmaniasis due to Leishmania infantum in Tunisia: Current status, challenges, and perspectives
PLOS Neglected Tropical Diseases: published March 12, 2026 | https://doi.org/10.1371/journal.pntd.0014063
The human immunome in the post-schistosomiasis mass drug administration era
PLOS Neglected Tropical Diseases: published March 16, 2026 | https://doi.org/10.1371/journal.pntd.0014084
Three decades of discovery: An overview of Hendra virus, the original Henipavirus
PLOS Neglected Tropical Diseases: published March 27, 2026 | https://doi.org/10.1371/journal.pntd.0014138
Research Articles
Understanding healing: A comparative analysis in chronic diseases with leprosy—A scoping review
PLOS Neglected Tropical Diseases: published March 2, 2026 | https://doi.org/10.1371/journal.pntd.0013748
Adult dengue vaccination in a low transmission setting: A modelling study in Singapore
PLOS Neglected Tropical Diseases: published March 2, 2026 | https://doi.org/10.1371/journal.pntd.0014062
First whole-genome detection of dengue virus in urban Aedes aegypti from Southern Brazil
PLOS Neglected Tropical Diseases: published March 2, 2026 | https://doi.org/10.1371/journal.pntd.0014050
The resistance to Toxoplasma gondii in Microtus fortis is associated with the activation of the complement lectin pathway
PLOS Neglected Tropical Diseases: published March 2, 2026 | https://doi.org/10.1371/journal.pntd.0014052
Anthrax-causing bacteria form biofilms on a soil-inspired porous glass bead model
PLOS Neglected Tropical Diseases: published March 3, 2026 | https://doi.org/10.1371/journal.pntd.0014043
The underestimated burden of placental schistosomiasis in endemic regions: Findings from a cross-sectional, diagnostic proof-of-concept study on placental schistosomiasis in Gabon
PLOS Neglected Tropical Diseases: published March 3, 2026 | https://doi.org/10.1371/journal.pntd.0014031
Comparative GWAS using global and Indian Reference Panels reveals non-coding drivers of COVID-19 severity and mortality
PLOS Neglected Tropical Diseases: published March 3, 2026 | https://doi.org/10.1371/journal.pntd.0014020
Occurrence of Angiostrongylus cantonensis in invasive snails in the French territories of America, French Guiana, Guadeloupe, and Martinique
PLOS Neglected Tropical Diseases: published March 3, 2026 | https://doi.org/10.1371/journal.pntd.0014024
First report of pathogenic Leptospira in Sri Lankan bats: A potential reservoir risk?
PLOS Neglected Tropical Diseases: published March 4, 2026 | https://doi.org/10.1371/journal.pntd.0012576
Social and environmental determinants of Neglected infectious diseases in quilombola communities of the Brazilian Amazon: An epidemiological and machine learning analysis
PLOS Neglected Tropical Diseases: published March 4, 2026 | https://doi.org/10.1371/journal.pntd.0014078
Modeling the potential distribution of Wesselsbron, Sindbis, and Middelburg viruses and their vectors in Africa under future climatic and land-use changes
PLOS Neglected Tropical Diseases: published March 4, 2026 | https://doi.org/10.1371/journal.pntd.0014072
Cm-p5, a synthetic antimicrobial peptide shows anti-Trypanosoma cruzi activity
PLOS Neglected Tropical Diseases: published March 5, 2026 | https://doi.org/10.1371/journal.pntd.0013975
Image segmentation of cervical grainy sandy patches lesions associated with female genital schistosomiasis using deep convolutional neural network with U-NET architecture
PLOS Neglected Tropical Diseases: published March 5, 2026 | https://doi.org/10.1371/journal.pntd.0014037
Evaluating how demography and temperature increase might alter the burden of congenital Toxoplasmosis in Africa
PLOS Neglected Tropical Diseases: published March 6, 2026 | https://doi.org/10.1371/journal.pntd.0014058
Study on the differentiated impact of climate change on plague epidemics in Northern and Southern China, 1912–1949
PLOS Neglected Tropical Diseases: published March 6, 2026 | https://doi.org/10.1371/journal.pntd.0014036
Association of avian biodiversity and West Nile Virus circulation in Culex mosquitoes in Emilia-Romagna, Italy
PLOS Neglected Tropical Diseases: published March 6, 2026 | https://doi.org/10.1371/journal.pntd.0014076
Comparative susceptibility of Old World and New World bat cell lines to Zika virus: Insights into viral replication and inflammatory responses
PLOS Neglected Tropical Diseases: published March 6, 2026 | https://doi.org/10.1371/journal.pntd.0014065
From tests to truth: A misclassification-aware machine learning framework for estimating brucellosis seroprevalence in wild canids
PLOS Neglected Tropical Diseases: published March 6, 2026 | https://doi.org/10.1371/journal.pntd.0014029
CCR8 orchestrates an immunosuppressive niche in the liver to promote Echinococcus multilocularis infection
PLOS Neglected Tropical Diseases: published March 6, 2026 | https://doi.org/10.1371/journal.pntd.0014018
Snakebite patterns in rural Sri Lanka and their implications for preventive measures
PLOS Neglected Tropical Diseases: published March 9, 2026 | https://doi.org/10.1371/journal.pntd.0014092
Human Leukocyte Antigen-G is enriched in presence of trypanosome in the dermis of individuals exposed to gambiense Human African Trypanosomiasis in Guinea and Côte d’Ivoire
PLOS Neglected Tropical Diseases: published March 9, 2026 | https://doi.org/10.1371/journal.pntd.0014085
Functionally-derivatized Nanoantibodies as novel tools for Giardia lamblia cyst detection
PLOS Neglected Tropical Diseases: published March 9, 2026 | https://doi.org/10.1371/journal.pntd.0013844
Spatial and social determinants of the 1857 yellow fever epidemic in Lisbon
PLOS Neglected Tropical Diseases: published March 9, 2026 | https://doi.org/10.1371/journal.pntd.0014059
First report of Providencia rettgeri, Colpodella spp., Ehrlichia spp., and Rickettsia hoogstraalii in ticks infesting goats of Pakistan
PLOS Neglected Tropical Diseases: published March 9, 2026 | https://doi.org/10.1371/journal.pntd.0014060
Spatio-temporal analysis and geostatistical modelling of onchocerciasis prevalence in Nigeria to support elimination efforts
PLOS Neglected Tropical Diseases: published March 9, 2026 | https://doi.org/10.1371/journal.pntd.0014090
Understanding the Rift Valley fever exposure risk: A comparative perspective from a multi-country study in East and Central Africa, 2021-24
PLOS Neglected Tropical Diseases: published March 10, 2026 | https://doi.org/10.1371/journal.pntd.0014082
A potential histoplasmosis pathogenesis mechanism mediated by a lectin of Histoplasma capsulatum with affinity to β-galactose, favoring intravascular hemagglutination
PLOS Neglected Tropical Diseases: published March 10, 2026 | https://doi.org/10.1371/journal.pntd.0014105
Scrub and murine typhus seroprevalence among blood donors in Laos
PLOS Neglected Tropical Diseases: published March 10, 2026 | https://doi.org/10.1371/journal.pntd.0014056
Current global estimates, risk factors, and knowledge gaps for Hepatitis E virus (HEV): A scoping review
PLOS Neglected Tropical Diseases: published March 11, 2026 | https://doi.org/10.1371/journal.pntd.0013980
Geospatial risk prediction of hookworm infection and intensity among school-aged children in Dak Lak province, Vietnam
PLOS Neglected Tropical Diseases: published March 12, 2026 | https://doi.org/10.1371/journal.pntd.0014079
A systematic review of dengue controlled human infection studies: safety, viral kinetics and immunology
PLOS Neglected Tropical Diseases: published March 12, 2026 | https://doi.org/10.1371/journal.pntd.0014086
Evaluation of the autonomic nervous system in autochthonous patients from Amazon with acute Chagas disease treated with benznidazole
PLOS Neglected Tropical Diseases: published March 12, 2026 | https://doi.org/10.1371/journal.pntd.0014022
Studies on prevalence of Hantavirus in small mammals in Southeast Asia: A systematic review and meta-analysis
PLOS Neglected Tropical Diseases: published March 12, 2026 | https://doi.org/10.1371/journal.pntd.0014075
Community participation and technological innovation: Baseline qualitative insights to inform a five-year cohort on drone-based dengue surveillance in Malaysia
PLOS Neglected Tropical Diseases: published March 12, 2026 | https://doi.org/10.1371/journal.pntd.0013979
Differentiating scrub typhus meningitis from brucellar meningitis in children: A single-center retrospective study
PLOS Neglected Tropical Diseases: published March 13, 2026 | https://doi.org/10.1371/journal.pntd.0014107
Acod1/itaconate axis controls anxiety-like behaviors induced by chronic infection of Toxoplasma gondii in mice
PLOS Neglected Tropical Diseases: published March 13, 2026 | https://doi.org/10.1371/journal.pntd.0014077
Zoonotic trypanosomatids in small mammals at a wildlife-urban interface in southeastern Brazil: Implications for transmission risk
PLOS Neglected Tropical Diseases: published March 13, 2026 | https://doi.org/10.1371/journal.pntd.0013455
The Cutaneous leishmaniasis impact questionnaire: Translation, cross-cultural adaptation and validation in adults with Cutaneous leishmaniasis in Ethiopia
PLOS Neglected Tropical Diseases: published March 13, 2026 | https://doi.org/10.1371/journal.pntd.0014073
Gut microbiota-associated metabolite N-acetyl-D-glucosamine alleviates systemic inflammatory responses induced by acute Toxoplasma gondii infection
PLOS Neglected Tropical Diseases: published March 13, 2026 | https://doi.org/10.1371/journal.pntd.0014108
External quality assessment for yaws elimination in low- and middle-income countries using plasmid-based proficiency test items
PLOS Neglected Tropical Diseases: published March 13, 2026 | https://doi.org/10.1371/journal.pntd.0013772
A prospective cohort study to describe the morphology of buboes in patients with bubonic plague using ultrasound imaging
PLOS Neglected Tropical Diseases: published March 16, 2026 | https://doi.org/10.1371/journal.pntd.0014133
Seroprevalence and preventive practices of dengue and chikungunya among school children in Bangkok: Gaps in prevention and vaccination strategies
PLOS Neglected Tropical Diseases: published March 16, 2026 | https://doi.org/10.1371/journal.pntd.0013026
Association between the 20-minute whole blood clotting test and fibrinogen concentrations in green pit viper envenomations in Bangkok
PLOS Neglected Tropical Diseases: published March 16, 2026 | https://doi.org/10.1371/journal.pntd.0014121
A country-wide survey of knowledge and practice regarding prevention, snake identification and pre-hospital management of children with snakebites amongst Public Health Midwives in Sri Lanka
PLOS Neglected Tropical Diseases: published March 16, 2026 | https://doi.org/10.1371/journal.pntd.0014083
Socioeconomic drivers of human Brucellosis in Ningxia, China: A one health and spatiotemporal analysis for targeted intervention
PLOS Neglected Tropical Diseases: published March 16, 2026 | https://doi.org/10.1371/journal.pntd.0014124
Fraction of sex-inducing substances facilitates growth and body shape change in a Fasciola hepatica/gigantica hybrid: A novel in vitro research platform for studying liver-stage juveniles derived from mice
PLOS Neglected Tropical Diseases: published March 16, 2026 | https://doi.org/10.1371/journal.pntd.0014113
Simultaneous serological assessment of four zoonotic rickettsiae among dogs near the United States-Mexico border
PLOS Neglected Tropical Diseases: published March 16, 2026 | https://doi.org/10.1371/journal.pntd.0014099
Unveiling the ecology and spatial dynamics of Trypanosoma cruzi, its DTUs and Triatoma vitticeps in the Atlantic Forest of south-eastern Espírito Santo State, Brazil
PLOS Neglected Tropical Diseases: published March 16, 2026 | https://doi.org/10.1371/journal.pntd.0014111
Suitable ecological niches of invasive malaria vector under present and projected climatic conditions in South of Iran
PLOS Neglected Tropical Diseases: published March 16, 2026 | https://doi.org/10.1371/journal.pntd.0014054
Population-based ultrasound prevalence and risk factors for cystic echinococcosis in endemic Kazakhstan
PLOS Neglected Tropical Diseases: published March 16, 2026 | https://doi.org/10.1371/journal.pntd.0014126
Scoping review of knowledge, attitudes, and practices to zoonotic diseases among abattoir workers and residents in proximity to abattoirs in low-middle income countries
PLOS Neglected Tropical Diseases: published March 16, 2026 | https://doi.org/10.1371/journal.pntd.0013235
Snakebite knowledge among healthcare workers in Gabon: A health facility-based cross-sectional survey
PLOS Neglected Tropical Diseases: published March 16, 2026 | https://doi.org/10.1371/journal.pntd.0013742
Hookworm genes encoding intestinal excreted-secreted proteins are transcriptionally upregulated in response to the host’s immune system
PLOS Neglected Tropical Diseases: published March 17, 2026 | https://doi.org/10.1371/journal.pntd.0014106
Outcomes of alternative therapy in HLA-B* 13:01 positive leprosy patients without dapsone versus standard MDT in negative patients: A comparative effectiveness study
PLOS Neglected Tropical Diseases: published March 17, 2026 | https://doi.org/10.1371/journal.pntd.0014114
Pandemic-driven immune imprinting accelerates evolution of human coronavirus OC43
PLOS Neglected Tropical Diseases: published March 17, 2026 | https://doi.org/10.1371/journal.pntd.0014109
DMEM and EMEM as alternate growth media for pathogenic Leptospira
PLOS Neglected Tropical Diseases: published March 17, 2026 | https://doi.org/10.1371/journal.pntd.0014136
Dengue transmission heterogeneity across Indonesia’s archipelago: Climate-driven spatiotemporal patterns and policy implications
PLOS Neglected Tropical Diseases: published March 17, 2026 | https://doi.org/10.1371/journal.pntd.0014135
Bispecific single-domain antibody (VHH) fused with human IgG1 Fc with dual specificity effectively neutralize Naja Kaouthia venom
PLOS Neglected Tropical Diseases: published March 17, 2026 | https://doi.org/10.1371/journal.pntd.0014119
Chikungunya viral load in cerebrospinal fluid and blood is not associated with severity of neurological manifestations in children
PLOS Neglected Tropical Diseases: published March 17, 2026 | https://doi.org/10.1371/journal.pntd.0014112
Noise and neglect: Social-media signals expose attention gaps for dengue, chikungunya, lymphatic filariasis and kala-azar in India’s vector-borne NTDs
PLOS Neglected Tropical Diseases: published March 18, 2026 | https://doi.org/10.1371/journal.pntd.0013378
Coinfection with malaria alters the fecundity and within-host persistence of an intestinal nematode
PLOS Neglected Tropical Diseases: published March 18, 2026 | https://doi.org/10.1371/journal.pntd.0013564
The spatio-temporal patterns and formation mechanisms of cholera epidemics in Hubei Province, China from 1949 to 2020
PLOS Neglected Tropical Diseases: published March 18, 2026 | https://doi.org/10.1371/journal.pntd.0014125
An artificial intelligence-powered digital pathology platform to support large-scale deworming programs against soil-transmitted helminthiasis and intestinal schistosomiasis in resource-limited settings
PLOS Neglected Tropical Diseases: published March 18, 2026 | https://doi.org/10.1371/journal.pntd.0013432
Prevalence, infection intensity, and risk factors of soil-transmitted helminthiasis and intestinal schistosomiasis among schoolchildren in Southern Ethiopia
PLOS Neglected Tropical Diseases: published March 18, 2026 | https://doi.org/10.1371/journal.pntd.0014115
Self-management of HTLV-1-associated myelopathy/tropical spastic paraparesis in Japan: A qualitative study
PLOS Neglected Tropical Diseases: published March 19, 2026 | https://doi.org/10.1371/journal.pntd.0014055
A miniaturized, frugal RPA assay for genus-level detection of Paracoccidioides spp. in resource-limited endemic settings
PLOS Neglected Tropical Diseases: published March 19, 2026 | https://doi.org/10.1371/journal.pntd.0014101
Genetic background and immune response in paracoccidioidomycosis: A systematic review and meta-analysis of single nucleotide variants
PLOS Neglected Tropical Diseases: published March 19, 2026 | https://doi.org/10.1371/journal.pntd.0014110
Human brucellosis in pregnancy in western Uganda: High seroprevalence and health risk factors identified in a cross-sectional study
PLOS Neglected Tropical Diseases: published March 20, 2026 | https://doi.org/10.1371/journal.pntd.0014123
Geographic, demographic and economic burden of human cystic echinococcosis in Italy based on hospital discharge records (2015–2022)
PLOS Neglected Tropical Diseases: published March 20, 2026 | https://doi.org/10.1371/journal.pntd.0014142
Shotgun metagenomic analysis of the oral microbiomes of children with noma
PLOS Neglected Tropical Diseases: published March 20, 2026 | https://doi.org/10.1371/journal.pntd.0014118
A time-varying geospatial model of habitat suitability for Japanese encephalitis virus vectors and vertebrate hosts in Australia
PLOS Neglected Tropical Diseases: published March 20, 2026 | https://doi.org/10.1371/journal.pntd.0014127
Targeting Leishmania donovani Sphingosine Kinase 1 using PF-543 enhances immune response and limits parasite load
PLOS Neglected Tropical Diseases: published March 20, 2026 | https://doi.org/10.1371/journal.pntd.0013102
The role of soluble thrombomodulin (sTM) in risk stratification of hemorrhagic fever with renal syndrome and prognostic assessment
PLOS Neglected Tropical Diseases: published March 20, 2026 | https://doi.org/10.1371/journal.pntd.0014132
Detection of Leishmania infantum DNA in captive wild mammals from an urban zoo in a visceral leishmaniasis–endemic area of Brazil
PLOS Neglected Tropical Diseases: published March 20, 2026 | https://doi.org/10.1371/journal.pntd.0014098
Characterization of arbovirus infections in patients within Haiti by screening discarded malaria rapid diagnostic test cassettes
PLOS Neglected Tropical Diseases: published March 20, 2026 | https://doi.org/10.1371/journal.pntd.0014089
Development and pilot application of a point-of-need molecular xenomonitoring protocol for tsetse (Glossina sp.) in a low-resource setting
PLOS Neglected Tropical Diseases: published March 23, 2026 | https://doi.org/10.1371/journal.pntd.0013706
Dengue transmission dynamics in an urban setting in western India
PLOS Neglected Tropical Diseases: published March 23, 2026 | https://doi.org/10.1371/journal.pntd.0013636
Brucella abortus and public health risk: Prevalence in milk sold at open markets in Cameroon
PLOS Neglected Tropical Diseases: published March 23, 2026 | https://doi.org/10.1371/journal.pntd.0014051
Descriptions of the natural history of erythema nodosum leprosum to inform clinical classification – A semi-systematic review
PLOS Neglected Tropical Diseases: published March 23, 2026 | https://doi.org/10.1371/journal.pntd.0014100
The differential roles of Giardia duodenalis-secreted tenascins in inducing intestinal epithelial cell apoptosis and the attributed EGFR-STAT3 axis regulation
PLOS Neglected Tropical Diseases: published March 23, 2026 | https://doi.org/10.1371/journal.pntd.0014153
Application of CRISPR/Cas13a system on the rapid detection of Salmonella spp.
PLOS Neglected Tropical Diseases: published March 23, 2026 | https://doi.org/10.1371/journal.pntd.0014150
Burden of cystic and alveolar echinococcosis in the Kyrgyz Republic
PLOS Neglected Tropical Diseases: published March 23, 2026 | https://doi.org/10.1371/journal.pntd.0014074
Vaccination of mice with Trichinella spiralis serine proteinase enhanced gut epithelial barrier and elicited a high protective immunity
PLOS Neglected Tropical Diseases: published March 24, 2026 | https://doi.org/10.1371/journal.pntd.0014161
Rapid identification of Biomphalaria spp. and diagnosis of Schistosoma mansoni infestation using MALDI-TOF mass spectrometry
PLOS Neglected Tropical Diseases: published March 24, 2026 | https://doi.org/10.1371/journal.pntd.0013236
Detection of Echinococcus multilocularis in coyotes in Washington State, USA highlights need for increased wildlife surveillance
PLOS Neglected Tropical Diseases: published March 24, 2026 | https://doi.org/10.1371/journal.pntd.0013502
Comparative studies of the effects of Naja ashei venom-derived proteins on model and native lipid membranes
PLOS Neglected Tropical Diseases: published March 25, 2026 | https://doi.org/10.1371/journal.pntd.0014122
A novel method for establishing a mouse model of hepatic echinococcosis: Ultrasound-guided percutaneous liver puncture modeling
PLOS Neglected Tropical Diseases: published March 25, 2026 | https://doi.org/10.1371/journal.pntd.0014154
A systematic review of adverse effects associated with systemic corticosteroids in the management of leprosy
PLOS Neglected Tropical Diseases: published March 26, 2026 | https://doi.org/10.1371/journal.pntd.0014152
Serotonin signaling modulates growth and motility in juvenile Fasciola hepatica
PLOS Neglected Tropical Diseases: published March 26, 2026 | https://doi.org/10.1371/journal.pntd.0014097
Delivery of canine rabies vaccination programme in Kutupalong-Balukhali refugee camps, Cox’s Bazar, Bangladesh
PLOS Neglected Tropical Diseases: published March 27, 2026 | https://doi.org/10.1371/journal.pntd.0014143
Genomic analysis of human-infecting Leptospira borgpetersenii isolates in Sri Lanka: Expanded PF07598 gene family repertoire and less genome reduction than bovine isolates
PLOS Neglected Tropical Diseases: published March 27, 2026 | https://doi.org/10.1371/journal.pntd.0012540
Reduced cytochrome P-450 (CYP) 2D6 activity and Plasmodium vivax malaria risk in Amazonians: A retrospective, population-based cohort study
PLOS Neglected Tropical Diseases: published March 27, 2026 | https://doi.org/10.1371/journal.pntd.0014160
Advanced machine learning approaches for predicting Neglected Tropical Disease co-endemicity in Kenya: A focus on soil-transmitted helminths, schistosomiasis, and lymphatic filariasis
PLOS Neglected Tropical Diseases: published March 30, 2026 | https://doi.org/10.1371/journal.pntd.0014156
Paralytic rabies outbreak mimicking guillain–Barré syndrome in French Amazonia
PLOS Neglected Tropical Diseases: published March 30, 2026 | https://doi.org/10.1371/journal.pntd.0014149
Assessment of the role of Haemophilus ducreyi coinfection on outcomes of Yaws treatment in the southwestern part of Ghana
PLOS Neglected Tropical Diseases: published March 30, 2026 | https://doi.org/10.1371/journal.pntd.0014182
Impact of projected climate and socioeconomic scenarios on state-wise annual dengue incidence in India using ensemble models
PLOS Neglected Tropical Diseases: published March 31, 2026 | https://doi.org/10.1371/journal.pntd.0014159
Corrections
Correction: Tracking the clinico-microbiological profile and molecular characterization of dengue cases during the monsoon-season in Belagavi, Karnataka
PLOS Neglected Tropical Diseases: published March 2, 2026 | https://doi.org/10.1371/journal.pntd.0014049
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Correction: Effects of temperature on the life history traits of intermediate host snails of fascioliasis: A systematic review
PLOS Neglected Tropical Diseases: published March 5, 2026 | https://doi.org/10.1371/journal.pntd.0014064
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Correction: Implementation of good clinical practice in clinical research in the context of limited resources settings: Lessons learnt from the freeBILy trial using an embedded mixed methods approach
PLOS Neglected Tropical Diseases: published March 10, 2026 | https://doi.org/10.1371/journal.pntd.0014087
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PLOS Neglected Tropical Diseases: published March 5, 2026 | https://doi.org/10.1371/journal.pntd.0014047