PLOS Neglected Tropical Diseases: Publishing science, accelerating research

Rousettus aegyptiacus bats at Python Cave, Queen Elizabeth National Park, showing their preference to form densely populated colonies, facilitating transmission and maintenance of zoonotic viruses such as Paramyxoviruses like Sosuga virus between bats. Amman et al.

Image Credit: Bobbie Erikson, Centers for Disease Control and Prevention

Editorial

Central Latin America: Two decades of challenges in neglected tropical disease control

Peter J. Hotez, Ashish Damania, Maria Elena Bottazzi

PLOS Neglected Tropical Diseases: published March 26, 2020 | https://doi.org/10.1371/journal.pntd.0007962

Viewpoints

A call to action for universal health coverage: Why we need to address gender inequities in the neglected tropical diseases community

Kim Ozano, Laura Dean, Mami Yoshimura, Eleanor MacPherson, Natalia Linou, Mariam Otmani del Barrio, Christine M. Halleux, Olumide Ogundahunsi, Sally Theobald

PLOS Neglected Tropical Diseases: published March 12, 2020 | https://doi.org/10.1371/journal.pntd.0007786

Symposiums

A case of hyperkeratotic crusted scabies

Adrian Cuellar-Barboza, Jesus A. Cardenas-de la Garza, José A. García-Lozano, Adrian Martinez-Moreno, Gildardo Jaramillo-Moreno, Jorge Ocampo-Candiani

PLOS Neglected Tropical Diseases: published March 5, 2020 | https://doi.org/10.1371/journal.pntd.0007918

Two cases of endoscopically diagnosed amebic colitis treated with paromomycin monotherapy

Kei Yamamoto, Yasuaki Yanagawa, Shinichi Oka, Koji Watanabe

PLOS Neglected Tropical Diseases: published March 19, 2020 | https://doi.org/10.1371/journal.pntd.0008013

Advanced case of PKDL due to delayed treatment: A rare case report

Roshan Kamal Topno, Vidya Nand Rabi Das, Maneesh Kumar, Major Madhukar, Krishna Pandey, Neena Verma, Kanhaiya Agrawal, Chandra Shekhar Lal, Niyamat Ali Siddiqui, Sanjiva Bimal, Pradeep Das

PLOS Neglected Tropical Diseases: published March 23, 2020 | https://doi.org/10.1371/journal.pntd.0008052

Research Articles

Seroprevalence of Crimean-Congo hemorrhagic fever in humans in the World Health Organization European region: A systematic review

Lía Monsalve-Arteaga, Montserrat Alonso-Sardón, Juan Luis Muñoz Bellido, María Belén Vicente Santiago, María Carmen Vieira Lista, Julio López Abán, Antonio Muro, Moncef Belhassen-García

PLOS Neglected Tropical Diseases: published March 2, 2020 | https://doi.org/10.1371/journal.pntd.0008094

Plasmodium vivax transcriptional profiling of low input cryopreserved isolates through the intraerythrocytic development cycle

Gabriel W. Rangel, Martha A. Clark, Usheer Kanjee, Jonathan M. Goldberg, Bronwyn MacInnis, Maria José Menezes, Marcelo U. Ferreira, Manoj T. Duraisingh

PLOS Neglected Tropical Diseases: published March 2, 2020 | https://doi.org/10.1371/journal.pntd.0008104

Polarized lung inflammation and Tie2/angiopoietin-mediated endothelial dysfunction during severe Orientia tsutsugamushi infection

Brandon Trent, Yuejin Liang, Yan Xing, Marisol Esqueda, Yang Wei, Nam-Hyuk Cho, Hong-Il Kim, Yeon-Sook Kim, Thomas R. Shelite, Jiyang Cai, Jiaren Sun, Donald H. Bouyer, Jinjun Liu, Lynn Soong

PLOS Neglected Tropical Diseases: published March 2, 2020 | https://doi.org/10.1371/journal.pntd.0007675

Projecting the future of dengue under climate change scenarios: Progress, uncertainties and research needs

Zhiwei Xu, Hilary Bambrick, Francesca D. Frentiu, Gregor Devine, Laith Yakob, Gail Williams, Wenbiao Hu

PLOS Neglected Tropical Diseases: published March 2, 2020 | https://doi.org/10.1371/journal.pntd.0008118

Evolutionary analysis of Mycobacterium bovis genotypes across Africa suggests co-evolution with livestock and humans

Osvaldo Frederico Inlamea, Pedro Soares, Cassia Yumi Ikuta, Marcos Bryan Heinemann, Sara Juma Achá, Adelina Machado, José Soares Ferreira Neto, Margarida Correia-Neves, Teresa Rito

PLOS Neglected Tropical Diseases: published March 2, 2020 | https://doi.org/10.1371/journal.pntd.0008081

Experimental infection of Egyptian rousette bats (Rousettus aegyptiacus) with Sosuga virus demonstrates potential transmission routes for a bat-borne human pathogenic paramyxovirus

Brian R. Amman, Amy J. Schuh, Tara K. Sealy, Jessica R. Spengler, Stephen R. Welch, Shannon G. M. Kirejczyk, César G. Albariño, Stuart T. Nichol, Jonathan S. Towner

PLOS Neglected Tropical Diseases: published March 2, 2020 | https://doi.org/10.1371/journal.pntd.0008092

Distinct gene expression patterns in vector-residing Leishmania infantum identify parasite stage-enriched markers

Iliano V. Coutinho-Abreu, Tiago D. Serafim, Claudio Meneses, Shaden Kamhawi, Fabiano Oliveira, Jesus G. Valenzuela

PLOS Neglected Tropical Diseases: published March 3, 2020 | https://doi.org/10.1371/journal.pntd.0008014

Genomic epidemiological characteristics of dengue fever in Guangdong province, China from 2013 to 2017

Bangyao Sun, Xin Zhang, Huan Zhang, Haizhou Liu, Lina Sun, Qiqi Tan, Mifang Liang, De Wu, Di Liu

PLOS Neglected Tropical Diseases: published March 3, 2020 | https://doi.org/10.1371/journal.pntd.0008049

Seroprevalence of EV-A71 neutralizing antibodies following the 2011 epidemic in HCMC, Vietnam

Fang-Lin Kuo, Truong Huu Khanh, Wan-Yu Chung, Nguyen Thanh Hung, Shu-Ting Luo, Wen-Chiung Chang, Le Nguyen Thanh Nhan, Le Quoc Thinh, Min-Shi Lee

PLOS Neglected Tropical Diseases: published March 3, 2020 | https://doi.org/10.1371/journal.pntd.0008124

Detection of dengue virus type 2 of Indian origin in acute febrile patients in rural Kenya

Moses Muia Masika, Essi M. Korhonen, Teemu Smura, Ruut Uusitalo, Katariina Vapalahti, Dufton Mwaengo, Anne J. Jääskeläinen, Omu Anzala, Olli Vapalahti, Eili Huhtamo

PLOS Neglected Tropical Diseases: published March 3, 2020 | https://doi.org/10.1371/journal.pntd.0008099

Responses of the putative trachoma vector, Musca sorbens, to volatile semiochemicals from human faeces

Ailie Robinson, Julie Bristow, Matthew V. Holl, Pateh Makalo, Wondu Alemayehu, Robin L. Bailey, David Macleod, Michael A. Birkett, John C. Caulfield, Virginia Sarah, John A. Pickett, Sarah Dewhirst, Vanessa Chen-Hussey, Christine M. Woodcock, Umberto D’Alessandro, Anna Last, Matthew J. Burton, Steve W. Lindsay, James G. Logan

PLOS Neglected Tropical Diseases: published March 3, 2020 | https://doi.org/10.1371/journal.pntd.0007719

Quantifying the socio-economic impact of leg lymphoedema on patient caregivers in a lymphatic filariasis and podoconiosis co-endemic district of Ethiopia

Thais Caprioli, Sarah Martindale, Asrat Mengiste, Dereje Assefa, Fikre H/Kiros, Mossie Tamiru, Nebiyu Negussu, Mark Taylor, Hannah Betts, Louise A. Kelly-Hope

PLOS Neglected Tropical Diseases: published March 3, 2020 | https://doi.org/10.1371/journal.pntd.0008058

Helminth infection modulates systemic pro-inflammatory cytokines and chemokines implicated in type 2 diabetes mellitus pathogenesis

Anuradha Rajamanickam, Saravanan Munisankar, Chandrakumar Dolla, Pradeep A. Menon, Kannan Thiruvengadam, Thomas B. Nutman, Subash Babu

PLOS Neglected Tropical Diseases: published March 3, 2020 | https://doi.org/10.1371/journal.pntd.0008101

Severe dengue categories as research endpoints—Results from a prospective observational study in hospitalised dengue patients

Kerstin D. Rosenberger, Neal Alexander, Eric Martinez, Lucy C. S. Lum, Carl-Erik Dempfle, Thomas Junghanss, Bridget Wills, Thomas Jaenisch, the DENCO Clinical Study Group

PLOS Neglected Tropical Diseases: published March 4, 2020 | https://doi.org/10.1371/journal.pntd.0008076

A LAMP-based colorimetric assay to expedite field surveillance of the invasive mosquito species Aedes aegypti and Aedes albopictus

Bixing Huang, Brian L. Montgomery, Rebecca Adamczyk, Gerhard Ehlers, Andrew F. van den Hurk, David Warrilow

PLOS Neglected Tropical Diseases: published March 4, 2020 | https://doi.org/10.1371/journal.pntd.0008130

Accounting for population structure reveals ambiguity in the Zaire Ebolavirus reservoir dynamics

Bram Vrancken, Tony Wawina-Bokalanga, Bert Vanmechelen, Joan Martí-Carreras, Miles W. Carroll, Justus Nsio, Jimmy Kapetshi, Sheila Makiala-Mandanda, Jean-Jacques Muyembe-Tamfum, Guy Baele, Kurt Vermeire, Valentijn Vergote, Steve Ahuka-Mundeke, Piet Maes

PLOS Neglected Tropical Diseases: published March 4, 2020 | https://doi.org/10.1371/journal.pntd.0008117

Detecting extra-ocular Chlamydia trachomatis in a trachoma-endemic community in Ethiopia: Identifying potential routes of transmission

Anna Last, Bart Versteeg, Oumer Shafi Abdurahman, Ailie Robinson, Gebeyehu Dumessa, Muluadam Abraham Aga, Gemechu Shumi Bejiga, Nebiyu Negussu, Katie Greenland, Alexandra Czerniewska, Nicholas Thomson, Sandy Cairncross, Virginia Sarah, David Macleod, Anthony W. Solomon, James Logan, Matthew J. Burton

PLOS Neglected Tropical Diseases: published March 4, 2020 | https://doi.org/10.1371/journal.pntd.0008120

Enabling animal rabies diagnostic in low-access areas: Sensitivity and specificity of a molecular diagnostic test from cerebral tissue dried on filter paper

Felana Suzah Rasolonjatovo, Hélène Guis, Malavika Rajeev, Laurent Dacheux, Lalaina Arivony Nomenjanahary, Girard Razafitrimo, Jean Théophile Rafisandrantantsoa, Catherine Cêtre-Sossah, Jean-Michel Heraud, Soa Fy Andriamandimby

PLOS Neglected Tropical Diseases: published March 6, 2020 | https://doi.org/10.1371/journal.pntd.0008116

Spatiotemporal variability in dengue transmission intensity in Jakarta, Indonesia

Megan O’Driscoll, Natsuko Imai, Neil M. Ferguson, Sri Rezeki Hadinegoro, Hindra Irawan Satari, Clarence C. Tam, Ilaria Dorigatti

PLOS Neglected Tropical Diseases: published March 6, 2020 | https://doi.org/10.1371/journal.pntd.0008102

The role of gender in Zika prevention behaviors in the Dominican Republic: Findings and programmatic implications from a qualitative study

Tilly Gurman, Anne Ballard Sara, Florentina Villanueva Lorenzo, Desirée Luis, Gabrielle Hunter, Sean Maloney, Ryanne Fujita-Conrads, Elli Leontsini

PLOS Neglected Tropical Diseases: published March 6, 2020 | https://doi.org/10.1371/journal.pntd.0007994

Long-term persistence of monotypic dengue transmission in small size isolated populations, French Polynesia, 1978-2014

Yoann Teissier, Richard Paul, Maite Aubry, Xavier Rodo, Carlos Dommar, Henrik Salje, Anavaj Sakuntabhai, Bernard Cazelles, Van-Mai Cao-Lormeau

PLOS Neglected Tropical Diseases: published March 6, 2020 | https://doi.org/10.1371/journal.pntd.0008110

Transmission center and driving factors of hand, foot, and mouth disease in China: A combined analysis

Yi Hu, Lili Xu, Hao Pan, Xun Shi, Yue Chen, Henry Lynn, Shenghua Mao, Huayi Zhang, Hailan Cao, Jun Zhang, Jing Zhang, Shuang Xiao, Jian Hu, Xiande Li, Shenjun Yao, Zhijie Zhang, Genming Zhao

PLOS Neglected Tropical Diseases: published March 9, 2020 | https://doi.org/10.1371/journal.pntd.0008070

Housing structure including the surrounding environment as a risk factor for visceral leishmaniasis transmission in Nepal

Lina Ghassan Younis, Axel Kroeger, Anand B. Joshi, Murari Lal Das, Mazin Omer, Vivek Kumar Singh, Chitra Kumar Gurung, Megha Raj Banjara

PLOS Neglected Tropical Diseases: published March 9, 2020 | https://doi.org/10.1371/journal.pntd.0008132

C19orf66 interrupts Zika virus replication by inducing lysosomal degradation of viral NS3

Yun Wu, Xinyu Yang, Zhicheng Yao, Xinhuai Dong, Danrui Zhang, Yiwen Hu, Shihao Zhang, Jiajie Lin, Jiahui Chen, Shu An, Hengming Ye, Shuqing Zhang, Ziying Qiu, Zhenjian He, Mingxing Huang, Guohong Wei, Xun Zhu

PLOS Neglected Tropical Diseases: published March 9, 2020 | https://doi.org/10.1371/journal.pntd.0008083

Human Plasmodium vivax diversity, population structure and evolutionary origin

Virginie Rougeron, Eric Elguero, Céline Arnathau, Beatriz Acuña Hidalgo, Patrick Durand, Sandrine Houze, Antoine Berry, Sedigheh Zakeri, Rashidul Haque, Mohammad Shafiul Alam, François Nosten, Carlo Severini, Tamirat Gebru Woldearegai, Benjamin Mordmüller, Peter Gottfried Kremsner, Lilia González-Cerón, Gustavo Fontecha, Dionicia Gamboa, Lise Musset, Eric Legrand, Oscar Noya, Tepanata Pumpaibool, Pingchai Harnyuttanakorn, Khadijetou Mint Lekweiry, Musab Mohamad Albsheer, Muzamil Mahdi Abdel Hamid, Ali Ould Mohamed Salem Boukary, Jean-François Trape, François Renaud, Franck Prugnolle

PLOS Neglected Tropical Diseases: published March 9, 2020 | https://doi.org/10.1371/journal.pntd.0008072

Single cell immune profiling of dengue virus patients reveals intact immune responses to Zika virus with enrichment of innate immune signatures

Yujiao Zhao, Matthew Amodio, Brent Vander Wyk, Bram Gerritsen, Mahesh M. Kumar, David van Dijk, Kevin Moon, Xiaomei Wang, Anna Malawista, Monique M. Richards, Megan E. Cahill, Anita Desai, Jayasree Sivadasan, Manjunatha M. Venkataswamy, Vasanthapuram Ravi, Erol Fikrig, Priti Kumar, Steven H. Kleinstein, Smita Krishnaswamy, Ruth R. Montgomery

PLOS Neglected Tropical Diseases: published March 9, 2020 | https://doi.org/10.1371/journal.pntd.0008112

Dispersal patterns of Trypanosoma cruzi in Arequipa, Peru

Alexander S. F. Berry, Renzo Salazar-Sánchez, Ricardo Castillo-Neyra, Katty Borrini-Mayorí, Claudia Arevalo-Nieto, Claudia Chipana-Ramos, Melina Vargas-Maquera, Jenny Ancca-Juarez, César Náquira-Velarde, Michael Z. Levy, Dustin Brisson

PLOS Neglected Tropical Diseases: published March 9, 2020 | https://doi.org/10.1371/journal.pntd.0007910

Potential distributions of Bacillus anthracis and Bacillus cereus biovar anthracis causing anthrax in Africa

Daniel Romero-Alvarez, A. Townsend Peterson, Johanna S. Salzer, Claudia Pittiglio, Sean Shadomy, Rita Traxler, Antonio R. Vieira, William A. Bower, Henry Walke, Lindsay P. Campbell

PLOS Neglected Tropical Diseases: published March 9, 2020 | https://doi.org/10.1371/journal.pntd.0008131

The impact of leprosy, podoconiosis and lymphatic filariasis on family quality of life: A qualitative study in Northwest Ethiopia

Anna T. van ‘t Noordende, Moges Wubie Aycheh, Alice Schippers

PLOS Neglected Tropical Diseases: published March 10, 2020 | https://doi.org/10.1371/journal.pntd.0008173

Targeted Sequencing of Genomic Repeat Regions Detects Circulating Cell-free Echinococcus DNA

Zhengqing Wan, Xiaoqing Peng, Lu Ma, Qingshan Tian, Shizheng Wu, Junqi Li, Jie Ling, Weigang Lv, Binrong Ding, Jieqiong Tan, Zhuohua Zhang

PLOS Neglected Tropical Diseases: published March 10, 2020 | https://doi.org/10.1371/journal.pntd.0008147

Wolbachia strain wAu efficiently blocks arbovirus transmission in Aedes albopictus

Maria Vittoria Mancini, Christie S. Herd, Thomas H. Ant, Shivan M. Murdochy, Steven P. Sinkins

PLOS Neglected Tropical Diseases: published March 10, 2020 | https://doi.org/10.1371/journal.pntd.0007926

Surveillance of Salmonella enterica serovar Typhi in Colombia, 2012–2015

Paula Diaz-Guevara, Lucy Angeline Montaño, Carolina Duarte, Gabriela Zabaleta, Mailis Maes, Julio Cesar Martinez Angarita, Duy Pham Thanh, William León-Quevedo, Carlos Castañeda-Orjuela, Claudia Jimena Alvarez Alvarez, Jaime Guerrero, Miriam Moroni, Josefina Campos, Enrique Pérez, Stephen Baker

PLOS Neglected Tropical Diseases: published March 10, 2020 | https://doi.org/10.1371/journal.pntd.0008040

Two monoclonal antibodies against glycoprotein Gn protect mice from Rift Valley Fever challenge by cooperative effects

Benjamin Gutjahr, Markus Keller, Melanie Rissmann, Felicitas von Arnim, Susanne Jäckel, Sven Reiche, Reiner Ulrich, Martin H. Groschup, Martin Eiden

PLOS Neglected Tropical Diseases: published March 11, 2020 | https://doi.org/10.1371/journal.pntd.0008143

The cyanobacterial saxitoxin exacerbates neural cell death and brain malformations induced by Zika virus

Carolina da S. G. Pedrosa, Leticia R. Q. Souza, Tiago A. Gomes, Caroline V. F. de Lima, Pitia F. Ledur, Karina Karmirian, Jimena Barbeito-Andres, Marcelo do N. Costa, Luiza M. Higa, Átila D. Rossi, Maria Bellio, Amilcar Tanuri, Arnaldo Prata-Barbosa, Fernanda Tovar-Moll, Patricia P. Garcez, Flavio A. Lara, Renato J. R. Molica, Stevens K. Rehen

PLOS Neglected Tropical Diseases: published March 12, 2020 | https://doi.org/10.1371/journal.pntd.0008060

Mapping the S1 and S1’ subsites of cysteine proteases with new dipeptidyl nitrile inhibitors as trypanocidal agents

Lorenzo Cianni, Carina Lemke, Erik Gilberg, Christian Feldmann, Fabiana Rosini, Fernanda dos Reis Rocho, Jean F. R. Ribeiro, Daiane Y. Tezuka, Carla D. Lopes, Sérgio de Albuquerque, Jürgen Bajorath, Stefan Laufer, Andrei Leitão, Michael Gütschow, Carlos A. Montanari

PLOS Neglected Tropical Diseases: published March 12, 2020 | https://doi.org/10.1371/journal.pntd.0007755

An integrated surgical training program for hepatic cystic echinococcosis in Xinjiang of China

Hongwei Zhang, Jian Yang, Jiang Li, Jing Yang, Yunbao Yu, Guisheng Liu, Yongguo Zhang, Long Zhang, Wei Guo, Abuduwayiti, Hong Sun, Shuxia Guo, Xueling Chen, Xiangwei Wu, Shijie Zhang, Xinyu Peng

PLOS Neglected Tropical Diseases: published March 12, 2020 | https://doi.org/10.1371/journal.pntd.0008023

Investigation of pyrimidine nucleoside analogues as chemical probes to assess compound effects on the proliferation of Trypanosoma cruzi intracellular parasites

Melissa Louise Sykes, David Hugh Hilko, Livia Isabella Kung, Sally-Ann Poulsen, Vicky Marie Avery

PLOS Neglected Tropical Diseases: published March 12, 2020 | https://doi.org/10.1371/journal.pntd.0008068

Prevalence of chronic chikungunya and associated risks factors in the French West Indies (La Martinique): A prospective cohort study

Antoine Bertolotti, Marême Thioune, Sylvie Abel, Gilda Belrose, Isabelle Calmont, Raymond Césaire, Minerva Cervantes, Laurence Fagour, Émilie Javelle, Catherine Lebris, Fatiha Najioullah, Sandrine Pierre-François, Benoît Rozé, Marie Vigan, Cédric Laouénan, André Cabié, the Chronic Chikungunya working group of University Medical Center of Martinique

PLOS Neglected Tropical Diseases: published March 12, 2020 | https://doi.org/10.1371/journal.pntd.0007327

The global seroprevalence of anti-Toxoplasma gondii antibodies in women who had spontaneous abortion: A systematic review and meta-analysis

Tooran Nayeri, Shahabeddin Sarvi, Mahmood Moosazadeh, Afsaneh Amouei, Zahra Hosseininejad, Ahmad Daryani

PLOS Neglected Tropical Diseases: published March 13, 2020 | https://doi.org/10.1371/journal.pntd.0008103

Identification of clinically approved small molecules that inhibit growth and affect transcript levels of developmentally regulated genes in the African trypanosome

Madison Elle Walsh, Eleanor Mary Naudzius, Savanah Jessica Diaz, Theodore William Wismar, Mikhail Martchenko Shilman, Danae Schulz

PLOS Neglected Tropical Diseases: published March 13, 2020 | https://doi.org/10.1371/journal.pntd.0007790

Immunogenicity of a killed bivalent whole cell oral cholera vaccine in forcibly displaced Myanmar nationals in Cox's Bazar, Bangladesh

Fahima Chowdhury, Taufiqur Rahman Bhuiyan, Afroza Akter, Md Saruar Bhuiyan, Ashraful Islam Khan, Motaher Hossain, Imam Tauheed, Tasnuva Ahmed, Shaumik Islam, Tanzeem Ahmed Rafique, Shah Alam Siddique, Nabila Binta Harun, Khaleda Islam, John D. Clemens, Firdausi Qadri

PLOS Neglected Tropical Diseases: published March 16, 2020 | https://doi.org/10.1371/journal.pntd.0007989

Design of multi-epitope peptides containing HLA class-I and class-II-restricted epitopes derived from immunogenic Leishmania proteins, and evaluation of CD4+ and CD8+ T cell responses induced in cured cutaneous leishmaniasis subjects

Sarra Hamrouni, Rachel Bras-Gonçalves, Abdelhamid Kidar, Karim Aoun, Rym Chamakh-Ayari, Elodie Petitdidier, Yasmine Messaoudi, Julie Pagniez, Jean-Loup Lemesre, Amel Meddeb-Garnaoui

PLOS Neglected Tropical Diseases: published March 16, 2020 | https://doi.org/10.1371/journal.pntd.0008093

The safety of combined triple drug therapy with ivermectin, diethylcarbamazine and albendazole in the neglected tropical diseases co-endemic setting of Fiji: A cluster randomised trial

Myra Hardy, Josaia Samuela, Mike Kama, Meciusela Tuicakau, Lucia Romani, Margot J. Whitfeld, Christopher L. King, Gary J. Weil, Anneke C. Grobler, Leanne J. Robinson, John M. Kaldor, Andrew C. Steer

PLOS Neglected Tropical Diseases: published March 16, 2020 | https://doi.org/10.1371/journal.pntd.0008106

Loss of pyrethroid resistance in newly established laboratory colonies of Aedes aegypti

Farah Z. Vera-Maloof, Karla Saavedra-Rodriguez, Rosa P. Penilla-Navarro, Americo D. Rodriguez-Ramirez, Felipe Dzul, Pablo Manrique-Saide, William C. Black IV

PLOS Neglected Tropical Diseases: published March 16, 2020 | https://doi.org/10.1371/journal.pntd.0007753

Anthropogenic landscapes increase Campylobacter jejuni infections in urbanizing banded mongoose (Mungos mungo): A one health approach

Sarah Medley, Monica Ponder, Kathleen A. Alexander

PLOS Neglected Tropical Diseases: published March 17, 2020 | https://doi.org/10.1371/journal.pntd.0007888

Impact of temperature on the extrinsic incubation period of Zika virus in Aedes aegypti

Olivia C. Winokur, Bradley J. Main, Jay Nicholson, Christopher M. Barker

PLOS Neglected Tropical Diseases: published March 18, 2020 | https://doi.org/10.1371/journal.pntd.0008047

Changes in historical typhoid transmission across 16 U.S. cities, 1889-1931: Quantifying the impact of investments in water and sewer infrastructures

Maile T. Phillips, Katharine A. Owers, Bryan T. Grenfell, Virginia E. Pitzer

PLOS Neglected Tropical Diseases: published March 18, 2020 | https://doi.org/10.1371/journal.pntd.0008048

Vaccination with single plasmid DNA encoding IL-12 and antigens of severe fever with thrombocytopenia syndrome virus elicits complete protection in IFNAR knockout mice

Jun-Gu Kang, Kyeongseok Jeon, Hooncheol Choi, Yuri Kim, Hong-Il Kim, Hyo-Jin Ro, Yong Bok Seo, Jua Shin, Junho Chung, Yoon Kyung Jeon, Yang Soo Kim, Keun Hwa Lee, Nam-Hyuk Cho

PLOS Neglected Tropical Diseases: published March 20, 2020 | https://doi.org/10.1371/journal.pntd.0007813

Feeding behavior and activity of Phlebotomus pedifer and potential reservoir hosts of Leishmania aethiopica in southwestern Ethiopia

Myrthe Pareyn, Abena Kochora, Luca Van Rooy, Nigatu Eligo, Bram Vanden Broecke, Nigatu Girma, Behailu Merdekios, Teklu Wegayehu, Louis Maes, Guy Caljon, Bernt Lindtjørn, Herwig Leirs, Fekadu Massebo

PLOS Neglected Tropical Diseases: published March 20, 2020 | https://doi.org/10.1371/journal.pntd.0007947

Identification of anisomycin, prodigiosin and obatoclax as compounds with broad-spectrum anti-parasitic activity

Gretchen Ehrenkaufer, Pengyang Li, Erin E. Stebbins, Monica M. Kangussu-Marcolino, Anjan Debnath, Corin V. White, Matthew S. Moser, Joseph DeRisi, Jolyn Gisselberg, Ellen Yeh, Steven C. Wang, Ana Hervella Company, Ludovica Monti, Conor R. Caffrey, Christopher D. Huston, Bo Wang, Upinder Singh

PLOS Neglected Tropical Diseases: published March 20, 2020 | https://doi.org/10.1371/journal.pntd.0008150

IL-6 produced by prostate epithelial cells stimulated with Trichomonas vaginalis promotes proliferation of prostate cancer cells by inducing M2 polarization of THP-1-derived macrophages

Ik-Hwan Han, Hyun-Ouk Song, Jae-Sook Ryu

PLOS Neglected Tropical Diseases: published March 20, 2020 | https://doi.org/10.1371/journal.pntd.0008126

Intracellular DNA replication and differentiation of Trypanosoma cruzi is asynchronous within individual host cells in vivo at all stages of infection

Martin C. Taylor, Alexander Ward, Francisco Olmo, Shiromani Jayawardhana, Amanda F. Francisco, Michael D. Lewis, John M. Kelly

PLOS Neglected Tropical Diseases: published March 20, 2020 | https://doi.org/10.1371/journal.pntd.0008007

Efficacy of single versus four repeated doses of praziquantel against Schistosoma mansoni infection in school-aged children from Côte d'Ivoire based on Kato-Katz and POC-CCA: An open-label, randomised controlled trial (RePST)

Pytsje T. Hoekstra, Miriam Casacuberta-Partal, Lisette van Lieshout, Paul L. A. M. Corstjens, Roula Tsonaka, Rufin K. Assaré, Kigbafori D. Silué, Aboulaye Meité, Eliézer K. N’Goran, Yves K. N’Gbesso, Abena S. Amoah, Meta Roestenberg, Stefanie Knopp, Jürg Utzinger, Jean T. Coulibaly, Govert J. van Dam

PLOS Neglected Tropical Diseases: published March 20, 2020 | https://doi.org/10.1371/journal.pntd.0008189

Using a Bayesian spatiotemporal model to identify the influencing factors and high-risk areas of hand, foot and mouth disease (HFMD) in Shenzhen

Xiaoyi He, Shengjie Dong, Liping Li, Xiaojian Liu, Yongsheng Wu, Zhen Zhang, Shujiang Mei

PLOS Neglected Tropical Diseases: published March 20, 2020 | https://doi.org/10.1371/journal.pntd.0008085

NS4/5 mutations enhance flavivirus Bamaga virus infectivity and pathogenicity in vitro and in vivo

Agathe M. G. Colmant, Helle Bielefeldt-Ohmann, Laura J. Vet, Caitlin A. O’Brien, Richard A. Bowen, Airn E. Hartwig, Steven Davis, Thisun B. H. Piyasena, Gervais Habarugira, Jessica J. Harrison, Jody Hobson-Peters, Roy A. Hall

PLOS Neglected Tropical Diseases: published March 23, 2020 | https://doi.org/10.1371/journal.pntd.0008166

Deep phosphoproteome analysis of Schistosoma mansoni leads development of a kinomic array that highlights sex-biased differences in adult worm protein phosphorylation

Natasha L. Hirst, Jean-Christophe Nebel, Scott P. Lawton, Anthony J. Walker

PLOS Neglected Tropical Diseases: published March 23, 2020 | https://doi.org/10.1371/journal.pntd.0008115

Comparison of clinical presentation and out-comes of Chikungunya and Dengue virus infections in patients with acute undifferentiated febrile illness from the Sindh region of Pakistan

Uzma Shahid, Joveria Q. Farooqi, Kelli L. Barr, S. Faisal Mahmood, Bushra Jamil, Kehkashan Imitaz, Zahida Azizullah, Faisal R. Malik, Dhani Prakoso, Maureen T. Long, Erum Khan

PLOS Neglected Tropical Diseases: published March 23, 2020 | https://doi.org/10.1371/journal.pntd.0008086

Prevalence of Mycobacterium leprae in armadillos in Brazil: A systematic review and meta-analysis

Patrícia Deps, João Marcelo Antunes, Adalberto Rezende Santos, Simon M. Collin

PLOS Neglected Tropical Diseases: published March 23, 2020 | https://doi.org/10.1371/journal.pntd.0008127

Different populations of Aedes aegypti and Aedes albopictus (Diptera: Culicidae) from Central Africa are susceptible to Zika virus infection

Basile Kamgang, Marie Vazeille, Armel Tedjou, Aurélie P. Yougang, Theodel A. Wilson-Bahun, Laurence Mousson, Charles S. Wondji, Anna-Bella Failloux

PLOS Neglected Tropical Diseases: published March 23, 2020 | https://doi.org/10.1371/journal.pntd.0008163

Leptospira interrogans and Leptospira kirschneri are the dominant Leptospira species causing human leptospirosis in Central Malaysia

Noraini Philip, Norliza Bahtiar Affendy, Siti Nur Alia Ramli, Muhamad Arif, Pappitha Raja, Elanngovan Nagandran, Pukunan Renganathan, Niazlin Mohd Taib, Siti Norbaya Masri, Muhamad Yazli Yuhana, Leslie Thian Lung Than, Mithra Seganathirajah, Cyrille Goarant, Marga G. A. Goris, Zamberi Sekawi, Vasantha Kumari Neela

PLOS Neglected Tropical Diseases: published March 23, 2020 | https://doi.org/10.1371/journal.pntd.0008197

Schistosoma species detection by environmental DNA assays in African freshwaters

Hind Alzaylaee, Rupert A. Collins, Gabriel Rinaldi, Asilatu Shechonge, Benjamin Ngatunga, Eric R. Morgan, Martin J. Genner

PLOS Neglected Tropical Diseases: published March 23, 2020 | https://doi.org/10.1371/journal.pntd.0008129

Comparison of anti-Vi IgG responses between two clinical studies of typhoid Vi conjugate vaccines (Vi-DT vs Vi-TT)

Eun Young Lee, Ju Yeon Park, Deok Ryun Kim, Manki Song, Sushant Sahastrabuddhe, Hun Kim, Yun Chon, Jae Seung Yang

PLOS Neglected Tropical Diseases: published March 23, 2020 | https://doi.org/10.1371/journal.pntd.0008171

Inhibition of invasive salmonella by orally administered IgA and IgG monoclonal antibodies

Angelene F. Richards, Jennifer E. Doering, Shannon A. Lozito, John J. Varrone, Graham G. Willsey, Michael Pauly, Kevin Whaley, Larry Zeitlin, Nicholas J. Mantis

PLOS Neglected Tropical Diseases: published March 23, 2020 | https://doi.org/10.1371/journal.pntd.0007803

Quantifying geographic accessibility to improve efficiency of entomological monitoring

Joshua Longbottom, Ana Krause, Stephen J. Torr, Michelle C. Stanton

PLOS Neglected Tropical Diseases: published March 23, 2020 | https://doi.org/10.1371/journal.pntd.0008096

ZIKA Virus infection in pregnant women in French Guiana: More precarious-more at risk

Edouard Hallet, Claude Flamand, Dominique Rousset, Timothée Bonifay, Camille Fritzell, Séverine Matheus, Maryvonne Dueymes, Balthazar Ntab, Mathieu Nacher

PLOS Neglected Tropical Diseases: published March 24, 2020 | https://doi.org/10.1371/journal.pntd.0008193

Economic benefits and costs of surgery for filarial hydrocele in Malawi

Larry Sawers, Eileen Stillwaggon, John Chiphwanya, Square Z. Mkwanda, Hannah Betts, Sarah Martindale, Louise A. Kelly-Hope

PLOS Neglected Tropical Diseases: published March 25, 2020 | https://doi.org/10.1371/journal.pntd.0008003

Evaluation of six commercial kits for the serological diagnosis of Mediterranean visceral leishmaniasis

Maude F. Lévêque, Emilie Battery, Pascal Delaunay, Badre Eddine Lmimouni, Karim Aoun, Coralie L’Ollivier, Patrick Bastien, Charles Mary, Christelle Pomares, Judith Fillaux, Laurence Lachaud

PLOS Neglected Tropical Diseases: published March 25, 2020 | https://doi.org/10.1371/journal.pntd.0008139

Inactivated rabies vaccines: Standardization of an in vitro assay for residual viable virus detection

Beatriz Lourenço Correia Moreira, Ana Paula Lappas Gimenez, Jorge Minor Fernandes Inagaki, Sonia Mara Raboni

PLOS Neglected Tropical Diseases: published March 25, 2020 | https://doi.org/10.1371/journal.pntd.0008142

A long-distance translocation initiated an outbreak of raccoon rabies in Hamilton, Ontario, Canada

Susan Nadin-Davis, Tore Buchanan, Larissa Nituch, Christine Fehlner-Gardiner

PLOS Neglected Tropical Diseases: published March 25, 2020 | https://doi.org/10.1371/journal.pntd.0008113

Molecular detection and identification of Leishmania DNA and blood meal analysis in Phlebotomus (Larroussius) species

Latifa Remadi, Najla Chargui, Maribel Jiménez, Ricardo Molina, Najoua Haouas, Estela González, Raja Chaabane-Banaouas, Eya Ben Salah, Mohsen Haddaji, Yassine Chaabouni, Hamouda Babba

PLOS Neglected Tropical Diseases: published March 26, 2020 | https://doi.org/10.1371/journal.pntd.0008077

Glutamine supplementation improves the efficacy of miltefosine treatment for visceral leishmaniasis

Carolina Ferreira, Inês Mesquita, Ana Margarida Barbosa, Nuno Sampaio Osório, Egídio Torrado, Charles-Joly Beauparlant, Arnaud Droit, Cristina Cunha, Agostinho Carvalho, Bhaskar Saha, Jerôme Estaquier, Ricardo Silvestre

PLOS Neglected Tropical Diseases: published March 26, 2020 | https://doi.org/10.1371/journal.pntd.0008125

Determining the viability of Schistosoma mansoni cercariae using fluorescence assays: An application for water treatment

Laura Braun, Lucinda Hazell, Alexander J. Webb, Fiona Allan, Aidan M. Emery, Michael R. Templeton

PLOS Neglected Tropical Diseases: published March 26, 2020 | https://doi.org/10.1371/journal.pntd.0008176

School-based health education for dengue control in Kelantan, Malaysia: Impact on knowledge, attitude and practice

Rattanam AhbiRami, Wan Fatma Zuharah

PLOS Neglected Tropical Diseases: published March 27, 2020 | https://doi.org/10.1371/journal.pntd.0008075

Assessment of control strategies against Clonorchis sinensis infection based on a multi-group dynamic transmission model

Xiao-Hong Huang, Men-Bao Qian, Guang-Hu Zhu, Yue-Yi Fang, Yuan-Tao Hao, Ying-Si Lai

PLOS Neglected Tropical Diseases: published March 27, 2020 | https://doi.org/10.1371/journal.pntd.0008152

A retrospective epidemiological analysis of human Cryptosporidium infection in China during the past three decades (1987-2018)

Aiqin Liu, Baiyan Gong, Xiaohua Liu, Yujuan Shen, Yanchen Wu, Weizhe Zhang, Jianping Cao

PLOS Neglected Tropical Diseases: published March 30, 2020 | https://doi.org/10.1371/journal.pntd.0008146

Cost of interventions to control schistosomiasis: A systematic review of the literature

Paola Salari, Thomas Fürst, Stefanie Knopp, Jürg Utzinger, Fabrizio Tediosi

PLOS Neglected Tropical Diseases: published March 30, 2020 | https://doi.org/10.1371/journal.pntd.0008098

Altered composition and functional profile of high-density lipoprotein in leprosy patients

Robertha Mariana R. Lemes, Carlos Adriano de M. e Silva, Maria Ângela de M. Marques, Georgia C. Atella, José Augusto da C. Nery, Maria Renata S. Nogueira, Patricia S. Rosa, Cléverson T. Soares, Prithwiraj De, Delphi Chatterjee, Maria Cristina V. Pessolani, Cristiana S. de Macedo

PLOS Neglected Tropical Diseases: published March 30, 2020 | https://doi.org/10.1371/journal.pntd.0008138

Is Sporothrix chilensis circulating outside Chile?

Carlos Alberto Tiburcio Valeriano, Reginaldo Gonçalves de Lima-Neto, Cícero Pinheiro Inácio, Vanessa Brito de Souza Rabello, Ertênia Paiva Oliveira, Rosely Maria Zancopé-Oliveira, Rodrigo Almeida-Paes, Rejane Pereira Neves, Manoel Marques Evangelista de Oliveira

PLOS Neglected Tropical Diseases: published March 30, 2020 | https://doi.org/10.1371/journal.pntd.0008151

Comprehensive response to Usutu virus following first isolation in blood donors in the Friuli Venezia Giulia region of Italy: Development of recombinant NS1-based serology and sensitivity to antiviral drugs

Ilaria Caracciolo, Erick Mora-Cardenas, Chiara Aloise, Tea Carletti, Ludovica Segat, Maria Sole Burali, Alexsia Chiarvesio, Vivianna Totis, Tatjana Avšič–Županc, Eloise Mastrangelo, Giuseppe Manfroni, Pierlanfranco D’Agaro, Alessandro Marcello

PLOS Neglected Tropical Diseases: published March 30, 2020 | https://doi.org/10.1371/journal.pntd.0008156

Dopaminergic antagonists inhibit bile chemotaxis of adult Clonorchis sinensis and its egg production

Fuhong Dai, Jin-Ho Song, Yeon Pyo Hong, Xuelian Bai, Woon-Mok Sohn, Sung-Jong Hong

PLOS Neglected Tropical Diseases: published March 30, 2020 | https://doi.org/10.1371/journal.pntd.0008220

Risk practices for bovine tuberculosis transmission to cattle and livestock farming communities living at wildlife-livestock-human interface in northern KwaZulu Natal, South Africa

Petronillah Rudo Sichewo, Catiane Vander Kelen, Séverine Thys, Anita Luise Michel

PLOS Neglected Tropical Diseases: published March 30, 2020 | https://doi.org/10.1371/journal.pntd.0007618

Decreasing fluconazole susceptibility of clinical South African Cryptococcus neoformans isolates over a decade

Serisha D. Naicker, Ruth S. Mpembe, Tsidiso G. Maphanga, Thokozile G. Zulu, Daniel Desanto, Jeannette Wadula, Nomonde Mvelase, Caroline Maluleka, Kessendri Reddy, Halima Dawood, Motlatji Maloba, Nelesh P. Govender, for GERMS-SA

PLOS Neglected Tropical Diseases: published March 31, 2020 | https://doi.org/10.1371/journal.pntd.0008137

March 2020

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