October 2014

Chagas disease is transmitted by hematophagous triatomine bugs, which can invade and sometimes adapt to houses. Vector control based on insecticide spraying and housing improvement is the main strategy used for Chagas disease prevention. Acceptance and participation in vector control is in turn greatly affected by how the disease and the bugs are perceived by communities. We have used children's drawings to explore their knowledge and perceptions of the bugs, to further engage communities in vector control activities. Children are very familiar with triatomine bugs, which they depict vividly, and this knowledge can be used to further improve Chagas disease awareness messages and community participation in disease control. See Yevstigneyeva et al.

Image Credit: Eric Dumonteil

Editorial

Tungiasis—A Neglected Disease with Many Challenges for Global Public Health

Hermann Feldmeier, Jorg Heukelbach, Uade Samuel Ugbomoiko, Elizabeth Sentongo, Pamela Mbabazi, Georg von Samson-Himmelstjerna, Ingela Krantz, The International Expert Group for Tungiasis

PLOS Neglected Tropical Diseases: published October 30, 2014 | https://doi.org/10.1371/journal.pntd.0003133

Viewpoints

First WHO Meeting of Stakeholders on Elimination of Gambiense Human African Trypanosomiasis

Peter Holmes

PLOS Neglected Tropical Diseases: published October 23, 2014 | https://doi.org/10.1371/journal.pntd.0003244

Policy Platform

Chagas Disease and the London Declaration on Neglected Tropical Diseases

Rick L. Tarleton, Ricardo E. Gürtler, Julio A. Urbina, Janine Ramsey, Rodolfo Viotti

PLOS Neglected Tropical Diseases: published October 9, 2014 | https://doi.org/10.1371/journal.pntd.0003219

Health Policies to Control Chagas Disease Transmission in European Countries

Ana Requena-Méndez, Pere Albajar-Viñas, Andrea Angheben, Peter Chiodini, Joaquim Gascón, José Muñoz, Chagas Disease COHEMI Working Group

PLOS Neglected Tropical Diseases: published October 30, 2014 | https://doi.org/10.1371/journal.pntd.0003245

Historical Profiles and Perspectives

Ibarapa Programme: Half a Century of Rural Health Service, Training, and International Cooperation in Nigeria

Oluwatoyin A. Asojo, Micheal C. Asuzu, Akindele O. Adebiyi

PLOS Neglected Tropical Diseases: published October 2, 2014 | https://doi.org/10.1371/journal.pntd.0003201

The Crosskey-Davies Experiment and Onchocerciasis Control in West Africa

Jesse B. Bump

PLOS Neglected Tropical Diseases: published October 9, 2014 | https://doi.org/10.1371/journal.pntd.0003223

Reviews

Leishmaniasis in the Middle East: Incidence and Epidemiology

Nasir Salam, Waleed Mohammed Al-Shaqha, Arezki Azzi

PLOS Neglected Tropical Diseases: published October 2, 2014 | https://doi.org/10.1371/journal.pntd.0003208

Iron Necessity: The Secret of Wolbachia's Success?

Alessandra Christina Gill, Alistair C. Darby, Benjamin L. Makepeace

PLOS Neglected Tropical Diseases: published October 16, 2014 | https://doi.org/10.1371/journal.pntd.0003224

Mycetoma Medical Therapy

Oliverio Welsh, Hail Mater Al-Abdely, Mario Cesar Salinas-Carmona, Ahmed Hassan Fahal

PLOS Neglected Tropical Diseases: published October 16, 2014 | https://doi.org/10.1371/journal.pntd.0003218

Current Treatment for Venom-Induced Consumption Coagulopathy Resulting from Snakebite

Kalana Maduwage, Geoffrey K. Isbister

PLOS Neglected Tropical Diseases: published October 23, 2014 | https://doi.org/10.1371/journal.pntd.0003220

Research Articles

Mycobacterium bovis in Burkina Faso: Epidemiologic and Genetic Links between Human and Cattle Isolates

Adama Sanou, Zekiba Tarnagda, Estelle Kanyala, Dezemon Zingué, Moumini Nouctara, Zakaria Ganamé, Adjima Combary, Hervé Hien, Mathurin Dembele, Antoinette Kabore, Nicolas Meda, Philippe Van de Perre, Dorine Neveu, Anne Laure Bañuls, Sylvain Godreuil

PLOS Neglected Tropical Diseases: published October 2, 2014 | https://doi.org/10.1371/journal.pntd.0003142

Brugia malayi Microfilariae Induce a Regulatory Monocyte/Macrophage Phenotype That Suppresses Innate and Adaptive Immune Responses

Noëlle Louise O'Regan, Svenja Steinfelder, Gopinath Venugopal, Gopala B. Rao, Richard Lucius, Aparna Srikantam, Susanne Hartmann

PLOS Neglected Tropical Diseases: published October 2, 2014 | https://doi.org/10.1371/journal.pntd.0003206

Ruthenium Complex with Benznidazole and Nitric Oxide as a New Candidate for the Treatment of Chagas Disease

Renata Sesti-Costa, Zumira A. Carneiro, Maria C. Silva, Maíta Santos, Grace K. Silva, Cristiane Milanezi, Roberto S. da Silva, João S. Silva

PLOS Neglected Tropical Diseases: published October 2, 2014 | https://doi.org/10.1371/journal.pntd.0003207

Evaluation of a Dengue NS1 Antigen Detection Assay Sensitivity and Specificity for the Diagnosis of Acute Dengue Virus Infection

Laura L. Hermann, Butsaya Thaisomboonsuk, Yongyuth Poolpanichupatam, Richard G. Jarman, Siripen Kalayanarooj, Ananda Nisalak, In-Kyu Yoon, Stefan Fernandez

PLOS Neglected Tropical Diseases: published October 2, 2014 | https://doi.org/10.1371/journal.pntd.0003193

Cryptosporidium Prevalence and Risk Factors among Mothers and Infants 0 to 6 Months in Rural and Semi-Rural Northwest Tanzania: A Prospective Cohort Study

Sarah H. Pedersen, Amanda L. Wilkinson, Aura Andreasen, David C. Warhurst, Safari M. Kinung'hi, Mark Urassa, Denna M. Mkwashapi, Jim Todd, John Changalucha, Joann M. McDermid

PLOS Neglected Tropical Diseases: published October 2, 2014 | https://doi.org/10.1371/journal.pntd.0003072

Cutaneous Leishmaniasis and Sand Fly Fluctuations Are Associated with El Niño in Panamá

Luis Fernando Chaves, José E. Calzada, Anayansí Valderrama, Azael Saldaña

PLOS Neglected Tropical Diseases: published October 2, 2014 | https://doi.org/10.1371/journal.pntd.0003210

Vector Competence in West African Aedes aegypti Is Flavivirus Species and Genotype Dependent

Laura B. Dickson, Irma Sanchez-Vargas, Massamba Sylla, Karen Fleming, William C. Black IV

PLOS Neglected Tropical Diseases: published October 2, 2014 | https://doi.org/10.1371/journal.pntd.0003153

Identification of Cell-Binding Adhesins of Leptospira interrogans

Karen V. Evangelista, Beth Hahn, Elsio A. Wunder Jr, Albert I. Ko, David A. Haake, Jenifer Coburn

PLOS Neglected Tropical Diseases: published October 2, 2014 | https://doi.org/10.1371/journal.pntd.0003215

Sources and Distribution of Surface Water Fecal Contamination and Prevalence of Schistosomiasis in a Brazilian Village

Rafael Ponce-Terashima, Amber M. Koskey, Mitermayer G. Reis, Sandra L. McLellan, Ronald E. Blanton

PLOS Neglected Tropical Diseases: published October 2, 2014 | https://doi.org/10.1371/journal.pntd.0003186

Contribution of the Community Health Volunteers in the Control of Buruli Ulcer in Bénin

Yves Thierry Barogui, Ghislain Emmanuel Sopoh, Roch Christian Johnson, Janine de Zeeuw, Ange Dodji Dossou, Jean Gabin Houezo, Annick Chauty, Julia Aguiar, Didier Agossadou, Patrick A. Edorh, Kingsley Asiedu, Tjip S. van der Werf, Ymkje Stienstra

PLOS Neglected Tropical Diseases: published October 2, 2014 | https://doi.org/10.1371/journal.pntd.0003200

Leishmania Specific CD4 T Cells Release IFNγ That Limits Parasite Replication in Patients with Visceral Leishmaniasis

Rajiv Kumar, Neetu Singh, Shalini Gautam, Om Prakash Singh, Kamlesh Gidwani, Madhukar Rai, David Sacks, Shyam Sundar, Susanne Nylén

PLOS Neglected Tropical Diseases: published October 2, 2014 | https://doi.org/10.1371/journal.pntd.0003198

Meta-analysis of the Effects of Insect Vector Saliva on Host Immune Responses and Infection of Vector-Transmitted Pathogens: A Focus on Leishmaniasis

Brittany Ockenfels, Edwin Michael, Mary Ann McDowell

PLOS Neglected Tropical Diseases: published October 2, 2014 | https://doi.org/10.1371/journal.pntd.0003197

New Developments of RNAi in Paracoccidioides brasiliensis: Prospects for High-Throughput, Genome-Wide, Functional Genomics

Tercio Goes, Elisa Flavia L. C. Bailão, Cristiane R. Correa, Adriana Bozzi, Luara I. Santos, Dawidson A. Gomes, Celia M. A. Soares, Alfredo M. Goes

PLOS Neglected Tropical Diseases: published October 2, 2014 | https://doi.org/10.1371/journal.pntd.0003173

Melarsoprol Sensitivity Profile of Trypanosoma brucei gambiense Isolates from Cured and Relapsed Sleeping Sickness Patients from the Democratic Republic of the Congo

Patient Pyana Pati, Nick Van Reet, Dieudonné Mumba Ngoyi, Ipos Ngay Lukusa, Stomy Karhemere Bin Shamamba, Philippe Büscher

PLOS Neglected Tropical Diseases: published October 2, 2014 | https://doi.org/10.1371/journal.pntd.0003212

Re-emergence of Rabies in the Guangxi Province of Southern China

Hai-Bo Tang, Yan Pan, Xian-Kai Wei, Zhuan-Ling Lu, Wu Lu, Jian Yang, Xiao-Xia He, Lin-Juan Xie, Lan Zeng, Lie-Feng Zheng, Yi Xiong, Nobuyuki Minamoto, Ting Rong Luo

PLOS Neglected Tropical Diseases: published October 2, 2014 | https://doi.org/10.1371/journal.pntd.0003114

High Fat Diet Modulates Trypanosoma cruzi Infection Associated Myocarditis

Fnu Nagajyothi, Louis M. Weiss, Dazhi Zhao, Wade Koba, Linda A. Jelicks, Min-Hui Cui, Stephen M. Factor, Philipp E. Scherer, Herbert B. Tanowitz

PLOS Neglected Tropical Diseases: published October 2, 2014 | https://doi.org/10.1371/journal.pntd.0003118

Analysis of Children's Perception of Triatomine Vectors of Chagas Disease through Drawings: Opportunities for Targeted Health Education

Violetta Yevstigneyeva, Javier Camara-Mejia, Eric Dumonteil

PLOS Neglected Tropical Diseases: published October 2, 2014 | https://doi.org/10.1371/journal.pntd.0003217

Biomarkers in Trypanosoma cruzi-Infected and Uninfected Individuals with Varying Severity of Cardiomyopathy in Santa Cruz, Bolivia

Emi E. Okamoto, Jacqueline E. Sherbuk, Eva H. Clark, Morgan A. Marks, Omar Gandarilla, Gerson Galdos-Cardenas, Angel Vasquez-Villar, Jeong Choi, Thomas C. Crawford, Rose Q., Antonio B. Fernandez, Rony Colanzi, Jorge Luis Flores-Franco, Robert H. Gilman, Caryn Bern, for the Chagas Disease Working Group in Bolivia and Peru

PLOS Neglected Tropical Diseases: published October 2, 2014 | https://doi.org/10.1371/journal.pntd.0003227

Molecular Epidemiology of Japanese Encephalitis Virus in Mosquitoes in Taiwan during 2005–2012

Chien-Ling Su, Cheng-Fen Yang, Hwa-Jen Teng, Liang-Chen Lu, Cheo Lin, Kun-Hsien Tsai, Yu-Yu Chen, Li-Yu Chen, Shu-Fen Chang, Pei-Yun Shu

PLOS Neglected Tropical Diseases: published October 2, 2014 | https://doi.org/10.1371/journal.pntd.0003122

Use of a Novel Chagas Urine Nanoparticle Test (Chunap) for Diagnosis of Congenital Chagas Disease

Yagahira E. Castro-Sesquen, Robert H. Gilman, Gerson Galdos-Cardenas, Lisbeth Ferrufino, Gerardo Sánchez, Edward Valencia Ayala, Lance Liotta, Caryn Bern, Alessandra Luchini, the Working Group on Chagas Disease in Bolivia and Peru

PLOS Neglected Tropical Diseases: published October 2, 2014 | https://doi.org/10.1371/journal.pntd.0003211

Detection of Rickettsia felis, Rickettsia typhi, Bartonella Species and Yersinia pestis in Fleas (Siphonaptera) from Africa

Hamza Leulmi, Cristina Socolovschi, Anne Laudisoit, Gualbert Houemenou, Bernard Davoust, Idir Bitam, Didier Raoult, Philippe Parola

PLOS Neglected Tropical Diseases: published October 9, 2014 | https://doi.org/10.1371/journal.pntd.0003152

No Apparent Reduction in Schistosome Burden or Genetic Diversity Following Four Years of School-Based Mass Drug Administration in Mwea, Central Kenya, a Heavy Transmission Area

Agola E. Lelo, David N. Mburu, Gabriel N. Magoma, Ben N. Mungai, Jimmy H. Kihara, Ibrahim N. Mwangi, Geoffrey M. Maina, Joseph M. Kinuthia, Martin W. Mutuku, Eric S. Loker, Gerald M. Mkoji, Michelle L. Steinauer

PLOS Neglected Tropical Diseases: published October 9, 2014 | https://doi.org/10.1371/journal.pntd.0003221

Symptomatic Dengue Infection during Pregnancy and Infant Outcomes: A Retrospective Cohort Study

Eleanor E. Friedman, Fadi Dallah, Emily W. Harville, Leann Myers, Pierre Buekens, Gerard Breart, Gabriel Carles

PLOS Neglected Tropical Diseases: published October 9, 2014 | https://doi.org/10.1371/journal.pntd.0003226

Assessment of Anthelmintic Efficacy of Mebendazole in School Children in Six Countries Where Soil-Transmitted Helminths Are Endemic

Bruno Levecke, Antonio Montresor, Marco Albonico, Shaali M. Ame, Jerzy M. Behnke, Jeffrey M. Bethony, Calvine D. Noumedem, Dirk Engels, Bertrand Guillard, Andrew C. Kotze, Alejandro J. Krolewiecki, James S. McCarthy, Zeleke Mekonnen, Maria V. Periago, Hem Sopheak, Louis-Albert Tchuem-Tchuenté, Tran Thanh Duong, Nguyen Thu Huong, Ahmed Zeynudin, Jozef Vercruysse

PLOS Neglected Tropical Diseases: published October 9, 2014 | https://doi.org/10.1371/journal.pntd.0003204

Prevalent and Incident HIV Diagnoses among Entamoeba histolytica-Infected Adult Males: A Changing Epidemiology Associated with Sexual Transmission — Taiwan, 2006–2013

Yi-Chun Lo, Dar-Der Ji, Chien-Ching Hung

PLOS Neglected Tropical Diseases: published October 9, 2014 | https://doi.org/10.1371/journal.pntd.0003222

Twelve Years of Rabies Surveillance in Sri Lanka, 1999–2010

Dushantha Karunanayake, Takashi Matsumoto, Omala Wimalaratne, Susilakanthi Nanayakkara, Devika Perera, Akira Nishizono, Kamruddin Ahmed

PLOS Neglected Tropical Diseases: published October 9, 2014 | https://doi.org/10.1371/journal.pntd.0003205

A Randomised, Double-Blind, Controlled Efficacy Trial of the LiESP/QA-21 Vaccine in Naïve Dogs Exposed to Two Leishmania infantum Transmission Seasons

Gaetano Oliva, Javier Nieto, Valentina Foglia Manzillo, Silvia Cappiello, Eleonora Fiorentino, Trentina Di Muccio, Aldo Scalone, Javier Moreno, Carmen Chicharro, Eugenia Carrillo, Therese Butaud, Laurie Guegand, Virginie Martin, Anne-Marie Cuisinier, David McGahie, Sylvie Gueguen, Carmen Cañavate, Luigi Gradoni

PLOS Neglected Tropical Diseases: published October 9, 2014 | https://doi.org/10.1371/journal.pntd.0003213

Key Source Habitats and Potential Dispersal of Triatoma infestans Populations in Northwestern Argentina: Implications for Vector Control

Ricardo E. Gürtler, María C. Cecere, María del Pilar Fernández, Gonzalo M. Vazquez-Prokopec, Leonardo A. Ceballos, Juan M. Gurevitz, Uriel Kitron, Joel E. Cohen

PLOS Neglected Tropical Diseases: published October 9, 2014 | https://doi.org/10.1371/journal.pntd.0003238

A Non-Stationary Relationship between Global Climate Phenomena and Human Plague Incidence in Madagascar

Katharina S. Kreppel, Cyril Caminade, Sandra Telfer, Minoarison Rajerison, Lila Rahalison, Andy Morse, Matthew Baylis

PLOS Neglected Tropical Diseases: published October 9, 2014 | https://doi.org/10.1371/journal.pntd.0003155

Last Generation Triazoles for Imported Eumycetoma in Eleven Consecutive Adults

Yoann Crabol, Sylvain Poiree, Marie-Elisabeth Bougnoux, Christophe Maunoury, Stéphane Barete, Valérie Zeller, Cédric Arvieux, Samuel Pineau, Karima Amazzough, Marc Lecuit, Fanny Lanternier, Olivier Lortholary, the French Mycosis Study Group

PLOS Neglected Tropical Diseases: published October 9, 2014 | https://doi.org/10.1371/journal.pntd.0003232

Benefit of Insecticide-Treated Nets, Curtains and Screening on Vector Borne Diseases, Excluding Malaria: A Systematic Review and Meta-analysis

Anne L. Wilson, Ramesh C. Dhiman, Uriel Kitron, Thomas W. Scott, Henk van den Berg, Steven W. Lindsay

PLOS Neglected Tropical Diseases: published October 9, 2014 | https://doi.org/10.1371/journal.pntd.0003228

Aedes hensilli as a Potential Vector of Chikungunya and Zika Viruses

Jeremy P. Ledermann, Laurent Guillaumot, Lawrence Yug, Steven C. Saweyog, Mary Tided, Paul Machieng, Moses Pretrick, Maria Marfel, Anne Griggs, Martin Bel, Mark R. Duffy, W. Thane Hancock, Tai Ho-Chen, Ann M. Powers

PLOS Neglected Tropical Diseases: published October 9, 2014 | https://doi.org/10.1371/journal.pntd.0003188

Physician Survey to Determine How Dengue Is Diagnosed, Treated and Reported in Puerto Rico

Kay M. Tomashek, Brad J. Biggerstaff, Mary M. Ramos, Carmen L. Pérez-Guerra, Enid J. Garcia Rivera, Wellington Sun

PLOS Neglected Tropical Diseases: published October 9, 2014 | https://doi.org/10.1371/journal.pntd.0003192

Hyperferritinaemia in Dengue Virus Infected Patients Is Associated with Immune Activation and Coagulation Disturbances

Cornelia A. M. van de Weg, Ralph M. H. G. Huits, Cláudio S. Pannuti, Rosalba M. Brouns, Riemsdijk W. A. van den Berg, Henk-Jan van den Ham, Byron E. E. Martina, Albert D. M. E. Osterhaus, Mihai G. Netea, Joost C. M. Meijers, Eric C. M. van Gorp, Esper G. Kallas

PLOS Neglected Tropical Diseases: published October 9, 2014 | https://doi.org/10.1371/journal.pntd.0003214

Early Double-Negative Thymocyte Export in Trypanosoma cruzi Infection Is Restricted by Sphingosine Receptors and Associated with Human Chagas Disease

Ailin Lepletier, Liliane de Almeida, Leonardo Santos, Luzia da Silva Sampaio, Bruno Paredes, Florencia Belén González, Célio Geraldo Freire-de-Lima, Juan Beloscar, Oscar Bottasso, Marcelo Einicker-Lamas, Ana Rosa Pérez, Wilson Savino, Alexandre Morrot

PLOS Neglected Tropical Diseases: published October 16, 2014 | https://doi.org/10.1371/journal.pntd.0003203

Dengue Virus Neutralizing Antibody Levels Associated with Protection from Infection in Thai Cluster Studies

Darunee Buddhari, Jared Aldstadt, Timothy P. Endy, Anon Srikiatkhachorn, Butsaya Thaisomboonsuk, Chonticha Klungthong, Ananda Nisalak, Benjawan Khuntirat, Richard G. Jarman, Stefan Fernandez, Stephen J. Thomas, Thomas W. Scott, Alan L. Rothman, In-Kyu Yoon

PLOS Neglected Tropical Diseases: published October 16, 2014 | https://doi.org/10.1371/journal.pntd.0003230

The Evolutionary History and Spatiotemporal Dynamics of the Fever, Thrombocytopenia and Leukocytopenia Syndrome Virus (FTLSV) in China

Xueyong Huang, Licheng Liu, Yanhua Du, Weili Wu, Haifeng Wang, Jia Su, Xiaoyan Tang, Qi Liu, Yinhui Yang, Yongqiang Jiang, Weijun Chen, Bianli Xu

PLOS Neglected Tropical Diseases: published October 16, 2014 | https://doi.org/10.1371/journal.pntd.0003237

Protection Motivation Theory in Predicting Intention to Engage in Protective Behaviors against Schistosomiasis among Middle School Students in Rural China

Han Xiao, Shiyue Li, Xinguang Chen, Bin Yu, Mengting Gao, Hong Yan, Chukwuemeka N. Okafor

PLOS Neglected Tropical Diseases: published October 16, 2014 | https://doi.org/10.1371/journal.pntd.0003246

Effect of Non-tuberculous Mycobacteria on Host Biomarkers Potentially Relevant for Tuberculosis Management

S. Dhanasekaran, Synne Jenum, Ruth Stavrum, Harald G. Wiker, John Kenneth, Mario Vaz, T. Mark Doherty, Harleen M. S. Grewal, TB Trials Study Group

PLOS Neglected Tropical Diseases: published October 16, 2014 | https://doi.org/10.1371/journal.pntd.0003243

New Insights in Cysticercosis Transmission

Carmen S. Arriola, Armando E. Gonzalez, Luis A. Gomez-Puerta, Maria T. Lopez-Urbina, Hector H. Garcia, Robert H. Gilman

PLOS Neglected Tropical Diseases: published October 16, 2014 | https://doi.org/10.1371/journal.pntd.0003247

Hepatotoxicity in Mice of a Novel Anti-parasite Drug Candidate Hydroxymethylnitrofurazone: A Comparison with Benznidazole

Carolina Davies, Nilay Dey, Olga Sanchez Negrette, Luis Antonio Parada, Miguel A. Basombrio, Nisha Jain Garg

PLOS Neglected Tropical Diseases: published October 16, 2014 | https://doi.org/10.1371/journal.pntd.0003231

Co-infections of Malaria and Geohelminthiasis in Two Rural Communities of Nkassomo and Vian in the Mfou Health District, Cameroon

Francis Zeukeng, Viviane Hélène Matong Tchinda, Jude Daiga Bigoga, Clovis Hugues Tiogang Seumen, Edward Shafe Ndzi, Géraldine Abonweh, Valérie Makoge, Amédée Motsebo, Roger Somo Moyou

PLOS Neglected Tropical Diseases: published October 16, 2014 | https://doi.org/10.1371/journal.pntd.0003236

Systems Biology Studies of Adult Paragonimus Lung Flukes Facilitate the Identification of Immunodominant Parasite Antigens

Samantha N. McNulty, Peter U. Fischer, R. Reid Townsend, Kurt C. Curtis, Gary J. Weil, Makedonka Mitreva

PLOS Neglected Tropical Diseases: published October 16, 2014 | https://doi.org/10.1371/journal.pntd.0003242

Mapping the Potential Risk of Mycetoma Infection in Sudan and South Sudan Using Ecological Niche Modeling

Abdallah M. Samy, Wendy W. J. van de Sande, Ahmed Hassan Fahal, A. Townsend Peterson

PLOS Neglected Tropical Diseases: published October 16, 2014 | https://doi.org/10.1371/journal.pntd.0003250

Hidden Population Structure and Cross-species Transmission of Whipworms (Trichuris sp.) in Humans and Non-human Primates in Uganda

Ria R. Ghai, Noah D. Simons, Colin A. Chapman, Patrick A. Omeja, T. Jonathan Davies, Nelson Ting, Tony L. Goldberg

PLOS Neglected Tropical Diseases: published October 23, 2014 | https://doi.org/10.1371/journal.pntd.0003256

Risk Factors for Bunyavirus-Associated Severe Fever with Thrombocytopenia Syndrome, China

Fan Ding, Xu-Hua Guan, Kai Kang, Shu-Jun Ding, Li-Yong Huang, Xue-Sen Xing, Sha Sha, Li Liu, Xian-Jun Wang, Xiao-Mei Zhang, Ai-Guo You, Yan-Hua Du, Hang Zhou, Sirenda Vong, Xiao-Dong Zhang, Zi-Jian Feng, Wei-Zhong Yang, Qun Li, Wen-Wu Yin

PLOS Neglected Tropical Diseases: published October 16, 2014 | https://doi.org/10.1371/journal.pntd.0003267

Crovirin, a Snake Venom Cysteine-Rich Secretory Protein (CRISP) with Promising Activity against Trypanosomes and Leishmania

Camila M. Adade, Ana Lúcia O. Carvalho, Marcelo A. Tomaz, Tatiana F. R. Costa, Joseane L. Godinho, Paulo A. Melo, Ana Paula C. A. Lima, Juliany C. F. Rodrigues, Russolina B. Zingali, Thaïs Souto-Padrón

PLOS Neglected Tropical Diseases: published October 16, 2014 | https://doi.org/10.1371/journal.pntd.0003252

Inhibition or Knockdown of ABC Transporters Enhances Susceptibility of Adult and Juvenile Schistosomes to Praziquantel

Ravi S. Kasinathan, Lalit Kumar Sharma, Charles Cunningham, Thomas R. Webb, Robert M. Greenberg

PLOS Neglected Tropical Diseases: published October 16, 2014 | https://doi.org/10.1371/journal.pntd.0003265

Protective Efficacy of a Plasmodium vivax Circumsporozoite Protein-Based Vaccine in Aotus nancymaae Is Associated with Antibodies to the Repeat Region

Anjali Yadava, Cysha E. Hall, JoAnn S. Sullivan, Douglas Nace, Tyrone Williams, William E. Collins, Christian F. Ockenhouse, John W. Barnwell

PLOS Neglected Tropical Diseases: published October 16, 2014 | https://doi.org/10.1371/journal.pntd.0003268

Impact of Schistosoma mansoni on Malaria Transmission in Sub-Saharan Africa

Martial L. Ndeffo Mbah, Laura Skrip, Scott Greenhalgh, Peter Hotez, Alison P. Galvani

PLOS Neglected Tropical Diseases: published October 16, 2014 | https://doi.org/10.1371/journal.pntd.0003234

Prevalence and Intensity of Soil-Transmitted Helminthiasis, Prevalence of Malaria and Nutritional Status of School Going Children in Honduras

Rosa Elena Mejia Torres, Dora Nelly Franco Garcia, Gustavo Adolfo Fontecha Sandoval, Adriana Hernandez Santana, Prabhjot Singh, Sandra Tamara Mancero Bucheli, Martha Saboya, Mirian Yolanda Paz

PLOS Neglected Tropical Diseases: published October 16, 2014 | https://doi.org/10.1371/journal.pntd.0003248

QTL Mapping of Genome Regions Controlling Temephos Resistance in Larvae of the Mosquito Aedes aegypti

Guadalupe del Carmen Reyes-Solis, Karla Saavedra-Rodriguez, Adriana Flores Suarez, William C. Black IV

PLOS Neglected Tropical Diseases: published October 16, 2014 | https://doi.org/10.1371/journal.pntd.0003177

The Phylogeography of Rabies in Grenada, West Indies, and Implications for Control

Ulrike Zieger, Denise A. Marston, Ravindra Sharma, Alfred Chikweto, Keshaw Tiwari, Muzzamil Sayyid, Bowen Louison, Hooman Goharriz, Katja Voller, Andrew C. Breed, Dirk Werling, Anthony R. Fooks, Daniel L. Horton

PLOS Neglected Tropical Diseases: published October 16, 2014 | https://doi.org/10.1371/journal.pntd.0003251

P. vivax Malaria and Dengue Fever Co-infection: A Cross-Sectional Study in the Brazilian Amazon

Belisa M. L. Magalhães, André M. Siqueira, Márcia A. A. Alexandre, Marcela S. Souza, João B. Gimaque, Michele S. Bastos, Regina M. P. Figueiredo, Gisely C. Melo, Marcus V. G. Lacerda, Maria P. G. Mourão

PLOS Neglected Tropical Diseases: published October 23, 2014 | https://doi.org/10.1371/journal.pntd.0003239

Evaluation of a Community-Based Trapping Program to Collect Simulium ochraceum sensu lato for Verification of Onchocerciasis Elimination

Mario A. Rodríguez-Pérez, Monsuru A. Adeleke, Isabel C. Rodríguez-Luna, Eddie W. Cupp, Thomas R. Unnasch

PLOS Neglected Tropical Diseases: published October 23, 2014 | https://doi.org/10.1371/journal.pntd.0003249

Multiplexed Digital mRNA Profiling of the Inflammatory Response in the West Nile Swiss Webster Mouse Model

José Peña, Jessica A. Plante, Alda Celena Carillo, Kimberly K. Roberts, Jennifer K. Smith, Terry L. Juelich, David W. C. Beasley, Alexander N. Freiberg, Montiago X. Labute, Pejman Naraghi-Arani

PLOS Neglected Tropical Diseases: published October 23, 2014 | https://doi.org/10.1371/journal.pntd.0003216

IgG1 as a Potential Biomarker of Post-chemotherapeutic Relapse in Visceral Leishmaniasis, and Adaptation to a Rapid Diagnostic Test

Tapan Bhattacharyya, Armon Ayandeh, Andrew K. Falconar, Shyam Sundar, Sayda El-Safi, Marissa A. Gripenberg, Duncan E. Bowes, Caroline Thunissen, Om Prakash Singh, Rajiv Kumar, Osman Ahmed, Osama Eisa, Alfarazdeg Saad, Sara Silva Pereira, Marleen Boelaert, Pascal Mertens, Michael A. Miles

PLOS Neglected Tropical Diseases: published October 23, 2014 | https://doi.org/10.1371/journal.pntd.0003273

Identification and Characterization of Hundreds of Potent and Selective Inhibitors of Trypanosoma brucei Growth from a Kinase-Targeted Library Screening Campaign

Rosario Diaz, Sandra A. Luengo-Arratta, João D. Seixas, Emanuele Amata, William Devine, Carlos Cordon-Obras, Domingo I. Rojas-Barros, Elena Jimenez, Fatima Ortega, Sabrinia Crouch, Gonzalo Colmenarejo, Jose Maria Fiandor, Jose Julio Martin, Manuela Berlanga, Silvia Gonzalez, Pilar Manzano, Miguel Navarro, Michael P. Pollastri

PLOS Neglected Tropical Diseases: published October 23, 2014 | https://doi.org/10.1371/journal.pntd.0003253

Chemotherapeutic Potential of 17-AAG against Cutaneous Leishmaniasis Caused by Leishmania (Viannia) braziliensis

Diego M. Santos, Antonio L. O. A. Petersen, Fabiana S. Celes, Valeria M. Borges, Patricia S. T. Veras, Camila I. de Oliveira

PLOS Neglected Tropical Diseases: published October 23, 2014 | https://doi.org/10.1371/journal.pntd.0003275

Evaluation of Commercially Available Diagnostic Tests for the Detection of Dengue Virus NS1 Antigen and Anti-Dengue Virus IgM Antibody

Elizabeth A. Hunsperger, Sutee Yoksan, Philippe Buchy, Vinh Chau Nguyen, Shamala Devi Sekaran, Delia A. Enria, Susana Vazquez, Elizabeth Cartozian, Jose L. Pelegrino, Harvey Artsob, Maria G. Guzman, Piero Olliaro, Julien Zwang, Martine Guillerm, Susie Kliks, Scott Halstead, Rosanna W. Peeling, Harold S. Margolis

PLOS Neglected Tropical Diseases: published October 16, 2014 | https://doi.org/10.1371/journal.pntd.0003171

A One Health Framework for the Evaluation of Rabies Control Programmes: A Case Study from Colombo City, Sri Lanka

Barbara Häsler, Elly Hiby, Will Gilbert, Nalinika Obeyesekere, Houda Bennani, Jonathan Rushton

PLOS Neglected Tropical Diseases: published October 23, 2014 | https://doi.org/10.1371/journal.pntd.0003270

Phylogeny and Niche Conservatism in North and Central American Triatomine Bugs (Hemiptera: Reduviidae: Triatominae), Vectors of Chagas' Disease

Carlos N. Ibarra-Cerdeña, Alejandro Zaldívar-Riverón, A. Townsend Peterson, Víctor Sánchez-Cordero, Janine M. Ramsey

PLOS Neglected Tropical Diseases: published October 30, 2014 | https://doi.org/10.1371/journal.pntd.0003266

Post-translational Modification of LipL32 during Leptospira interrogans Infection

Timothy D. Witchell, Azad Eshghi, Jarlath E. Nally, Rebecca Hof, Martin J. Boulanger, Elsio A. Wunder Jr., Albert I. Ko, David A. Haake, Caroline E. Cameron

PLOS Neglected Tropical Diseases: published October 30, 2014 | https://doi.org/10.1371/journal.pntd.0003280

A New Model for Management of Mycetoma in the Sudan

Ahmed Fahal, El Sheikh Mahgoub, Ahmed Mohamed EL Hassan, Manar Elsheikh Abdel-Rahman, Yassir Alshambaty, Ahmed Hashim, Ali Hago, Eduard E. Zijlstra

PLOS Neglected Tropical Diseases: published October 30, 2014 | https://doi.org/10.1371/journal.pntd.0003271

Caseating Granulomas in Cutaneous Leishmaniasis

Jessica Aoun, Robert Habib, Khalil Charaffeddine, Suad Taraif, Asif Loya, Ibrahim Khalifeh

PLOS Neglected Tropical Diseases: published October 23, 2014 | https://doi.org/10.1371/journal.pntd.0003255

Effectiveness of Insecticide Spraying and Culling of Dogs on the Incidence of Leishmania infantum Infection in Humans: A Cluster Randomized Trial in Teresina, Brazil

Guilherme L. Werneck, Carlos H. N. Costa, Fernando Aécio Amorim de Carvalho, Maria do Socorro Pires e Cruz, James H. Maguire, Marcia C. Castro

PLOS Neglected Tropical Diseases: published October 30, 2014 | https://doi.org/10.1371/journal.pntd.0003172

Improvements on Restricted Insecticide Application Protocol for Control of Human and Animal African Trypanosomiasis in Eastern Uganda

Dennis Muhanguzi, Kim Picozzi, Jan Hatendorf, Michael Thrusfield, Susan Christina Welburn, John David Kabasa, Charles Waiswa

PLOS Neglected Tropical Diseases: published October 30, 2014 | https://doi.org/10.1371/journal.pntd.0003284

Dengue Virus Infections among Haitian and Expatriate Non-governmental Organization Workers — Léogane and Port-au-Prince, Haiti, 2012

Stephanie J. Salyer, Esther M. Ellis, Corvil Salomon, Christophe Bron, Stanley Juin, Ryan R. Hemme, Elizabeth Hunsperger, Emily S. Jentes, Roc Magloire, Kay M. Tomashek, Anne Marie Desormeaux, Jorge L. Muñoz-Jordán, Lesly Etienne, Manuela Beltran, Tyler M. Sharp, Daphne Moffett, Jordan Tappero, Harold S. Margolis, Mark A. Katz

PLOS Neglected Tropical Diseases: published October 30, 2014 | https://doi.org/10.1371/journal.pntd.0003269

Quantifying the Contribution of Hosts with Different Parasite Concentrations to the Transmission of Visceral Leishmaniasis in Ethiopia

Ezer Miller, Alon Warburg, Ilya Novikov, Asrat Hailu, Petr Volf, Veronika Seblova, Amit Huppert

PLOS Neglected Tropical Diseases: published October 30, 2014 | https://doi.org/10.1371/journal.pntd.0003288

Evidence for Co-evolution of West Nile Virus and House Sparrows in North America

Nisha K. Duggal, Angela Bosco-Lauth, Richard A. Bowen, Sarah S. Wheeler, William K. Reisen, Todd A. Felix, Brian R. Mann, Hannah Romo, Daniele M. Swetnam, Alan D. T. Barrett, Aaron C. Brault

PLOS Neglected Tropical Diseases: published October 30, 2014 | https://doi.org/10.1371/journal.pntd.0003262

Forecasting Temporal Dynamics of Cutaneous Leishmaniasis in Northeast Brazil

Joseph A. Lewnard, Lara Jirmanus, Nivison Nery Júnior, Paulo R. Machado, Marshall J. Glesby, Albert I. Ko, Edgar M. Carvalho, Albert Schriefer, Daniel M. Weinberger

PLOS Neglected Tropical Diseases: published October 30, 2014 | https://doi.org/10.1371/journal.pntd.0003283

Corrections

Correction: Activity In Vivo of Anti-Trypanosoma cruzi Compounds Selected from a High Throughput Screening

The PLOS Neglected Tropical Diseases Staff

PLOS Neglected Tropical Diseases: published October 7, 2014 | https://doi.org/10.1371/journal.pntd.0003293

Correction: Use of Humanised Rat Basophilic Leukaemia Cell Line RS-ATL8 for the Assessment of Allergenicity of Schistosoma mansoni Proteins

The PLOS Neglected Tropical Diseases Staff

PLOS Neglected Tropical Diseases: published October 22, 2014 | https://doi.org/10.1371/journal.pntd.0003331

Correction: Using Molecular Epidemiology to Track Toxoplasma gondii from Terrestrial Carnivores to Marine Hosts: Implications for Public Health and Conservation

The PLOS Neglected Tropical Diseases Staff

PLOS Neglected Tropical Diseases: published October 27, 2014 | https://doi.org/10.1371/journal.pntd.0003340

Correction: Biomarkers in Trypanosoma cruzi-Infected and Uninfected Individuals with Varying Severity of Cardiomyopathy in Santa Cruz, Bolivia

The PLOS Neglected Tropical Diseases Staff

PLOS Neglected Tropical Diseases: published October 30, 2014 | https://doi.org/10.1371/journal.pntd.0003362

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Children's perception of Chagas disease vectors in Yucatan, Mexico

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