Accompanying the severe and widespread impacts of SARS-CoV-2 infection on hospitalizations and deaths in many countries around the world, evidence of chronic health sequelae has emerged. These manifestations can range from fatigue, shortness of breath, anxiety and depression to other serious instances of organ dysfunction, including pulmonary fibrosis and renal failure. In a Perspective, Kieran Quinn and Chaim Bell discuss an accompanying research study from Krishnan Bhaskaran and co-workers on people hospitalized with COVID-19 in England, as compared with the general population and those with influenza, and address the evolving area of health policy and planning related to the care of patients after hospitalization for COVID-19.
Image Credit: National Cancer Institute, Unsplash
Perspectives
Reporting bias in clinical trials: Progress toward transparency and next steps
PLOS Medicine: published January 19, 2022 | https://doi.org/10.1371/journal.pmed.1003894
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Pandemic health consequences: Grasping the long COVID tail
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Collection Review
Clinical impact of vivax malaria: A collection review
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Research Articles
Hypertension awareness, treatment, and control and their association with healthcare access in the middle-aged and older Indian population: A nationwide cohort study
PLOS Medicine: published January 4, 2022 | https://doi.org/10.1371/journal.pmed.1003855
The impact of removing financial incentives and/or audit and feedback on chlamydia testing in general practice: A cluster randomised controlled trial (ACCEPt-able)
PLOS Medicine: published January 4, 2022 | https://doi.org/10.1371/journal.pmed.1003858
GP-delivered medication review of polypharmacy, deprescribing, and patient priorities in older people with multimorbidity in Irish primary care (SPPiRE Study): A cluster randomised controlled trial
PLOS Medicine: published January 5, 2022 | https://doi.org/10.1371/journal.pmed.1003862
Plant-based diets and incident cardiovascular disease and all-cause mortality in African Americans: A cohort study
PLOS Medicine: published January 5, 2022 | https://doi.org/10.1371/journal.pmed.1003863
Use of open-text responses to recode categorical survey data on postpartum contraception use among women in the United States: A mixed-methods inquiry of Pregnancy Risk Assessment Monitoring System data
PLOS Medicine: published January 5, 2022 | https://doi.org/10.1371/journal.pmed.1003878
Peer-led counselling with problem discussion therapy for adolescents living with HIV in Zimbabwe: A cluster-randomised trial
PLOS Medicine: published January 5, 2022 | https://doi.org/10.1371/journal.pmed.1003887
Sex-specific associations of adiposity with cardiometabolic traits in the UK: A multi–life stage cohort study with repeat metabolomics
PLOS Medicine: published January 6, 2022 | https://doi.org/10.1371/journal.pmed.1003636
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Factors associated with excess all-cause mortality in the first wave of the COVID-19 pandemic in the UK: A time series analysis using the Clinical Practice Research Datalink
PLOS Medicine: published January 6, 2022 | https://doi.org/10.1371/journal.pmed.1003870
Obstetric interventions and pregnancy outcomes during the COVID-19 pandemic in England: A nationwide cohort study
PLOS Medicine: published January 10, 2022 | https://doi.org/10.1371/journal.pmed.1003884
Protection against discrimination in national dementia guideline recommendations: A systematic review
PLOS Medicine: published January 11, 2022 | https://doi.org/10.1371/journal.pmed.1003860
Safety and immunogenicity of 2-dose heterologous Ad26.ZEBOV, MVA-BN-Filo Ebola vaccination in children and adolescents in Africa: A randomised, placebo-controlled, multicentre Phase II clinical trial
PLOS Medicine: published January 11, 2022 | https://doi.org/10.1371/journal.pmed.1003865
Political rationale, aims, and outcomes of health-related high-level meetings and special sessions at the UN General Assembly: A policy research observational study
PLOS Medicine: published January 13, 2022 | https://doi.org/10.1371/journal.pmed.1003873
Low-dose aspirin and incidence of lung carcinoma in patients with chronic obstructive pulmonary disease in Hong Kong: A cohort study
PLOS Medicine: published January 13, 2022 | https://doi.org/10.1371/journal.pmed.1003880
Association of serum 25-hydroxyvitamin D concentrations with risk of dementia among individuals with type 2 diabetes: A cohort study in the UK Biobank
PLOS Medicine: published January 13, 2022 | https://doi.org/10.1371/journal.pmed.1003906
A nationwide school fruit and vegetable policy and childhood and adolescent overweight: A quasi-natural experimental study
PLOS Medicine: published January 18, 2022 | https://doi.org/10.1371/journal.pmed.1003881
Effects of preconception lifestyle intervention in infertile women with obesity: The FIT-PLESE randomized controlled trial
PLOS Medicine: published January 18, 2022 | https://doi.org/10.1371/journal.pmed.1003883
Integrating tuberculosis and noncommunicable diseases care in low- and middle-income countries (LMICs): A systematic review
PLOS Medicine: published January 18, 2022 | https://doi.org/10.1371/journal.pmed.1003899
Selective publication of antidepressant trials and its influence on apparent efficacy: Updated comparisons and meta-analyses of newer versus older trials
PLOS Medicine: published January 19, 2022 | https://doi.org/10.1371/journal.pmed.1003886
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Population sizes, HIV prevalence, and HIV prevention among men who paid for sex in sub-Saharan Africa (2000–2020): A meta-analysis of 87 population-based surveys
PLOS Medicine: published January 25, 2022 | https://doi.org/10.1371/journal.pmed.1003861
Overall and cause-specific hospitalisation and death after COVID-19 hospitalisation in England: A cohort study using linked primary care, secondary care, and death registration data in the OpenSAFELY platform
PLOS Medicine: published January 25, 2022 | https://doi.org/10.1371/journal.pmed.1003871
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Ruling out pulmonary embolism across different healthcare settings: A systematic review and individual patient data meta-analysis
PLOS Medicine: published January 25, 2022 | https://doi.org/10.1371/journal.pmed.1003905
The relationship between lipoprotein A and other lipids with prostate cancer risk: A multivariable Mendelian randomisation study
PLOS Medicine: published January 27, 2022 | https://doi.org/10.1371/journal.pmed.1003859
Psychiatric comorbidity and risk of premature mortality and suicide among those with chronic respiratory diseases, cardiovascular diseases, and diabetes in Sweden: A nationwide matched cohort study of over 1 million patients and their unaffected siblings
PLOS Medicine: published January 27, 2022 | https://doi.org/10.1371/journal.pmed.1003864