September 2021

The health, wellbeing and development of children and adolescents is fundamental to human societies and their future prospects, worldwide. In many settings, however, major threats to child health are evident, ranging from poverty and undernutrition to the adverse impacts of conflict and climate change. Moreover, the COVID-19 pandemic is expected to have serious impacts on education and other services for children. A Special Issue of PLOS Medicine is devoted to the theme of child and adolescent health and, in an Editorial, guest editors Zulfiqar Bhutta, Kathryn Yount and Quique Bassat, along with journal editor Caitlin Moyer, discuss the aims and content of the issue.

Featured article: Sustainable Developmental Goals Interrupted...

Image Credit: Tri Le, Pixabay

Editorials

Call for emergency action to limit global temperature increases, restore biodiversity, and protect health

Lukoye Atwoli, Abdullah H. Baqui, Thomas Benfield, Raffaella Bosurgi, Fiona Godlee, Stephen Hancocks, Richard Horton, Laurie Laybourn-Langton, Carlos Augusto Monteiro, Ian Norman, Kirsten Patrick, Nigel Praities, Marcel GM Olde Rikkert, Eric J. Rubin, Peush Sahni, Richard Smith, Nick Talley, Sue Turale, Damián Vázquez

PLOS Medicine: published September 7, 2021 | https://doi.org/10.1371/journal.pmed.1003755

Special Issue Editor’s choice: Global child health from birth to adolescence and beyond

Caitlin Moyer

PLOS Medicine: published September 28, 2021 | https://doi.org/10.1371/journal.pmed.1003800

Sustainable Developmental Goals interrupted: Overcoming challenges to global child and adolescent health

Zulfiqar A. Bhutta, Kathryn M. Yount, Quique Bassat, Caitlin E. Moyer

PLOS Medicine: published September 28, 2021 | https://doi.org/10.1371/journal.pmed.1003802

Perspectives

Understanding how unhealthy food companies influence advertising restrictions

Stanton A. Glantz

PLOS Medicine: published September 2, 2021 | https://doi.org/10.1371/journal.pmed.1003742

Assisted reproduction technology and long-term cardiometabolic health in the offspring

Ronald C. W. Ma, Noel Y. H. Ng, Lai Ping Cheung

PLOS Medicine: published September 7, 2021 | https://doi.org/10.1371/journal.pmed.1003724

Achieving global equity for COVID-19 vaccines: Stronger international partnerships and greater advocacy and solidarity are needed

J Peter Figueroa, Peter J. Hotez, Carolina Batista, Yanis Ben Amor, Onder Ergonul, Sarah Gilbert, Mayda Gursel, Mazen Hassanain, Gagandeep Kang, David C. Kaslow, Jerome H. Kim, Bhavna Lall, Heidi Larson, Denise Naniche, Timothy Sheahan, Shmuel Shoham, Annelies Wilder-Smith, Samba O. Sow, Nathalie Strub-Wourgaft, Prashant Yadav, Maria Elena Bottazzi

PLOS Medicine: published September 13, 2021 | https://doi.org/10.1371/journal.pmed.1003772

Tuberculosis preventive treatment in people living with HIV—Is the glass half empty or half full?

Olivia Oxlade, Hannah Rochon, Jonathon R. Campbell, Dick Menzies

PLOS Medicine: published September 14, 2021 | https://doi.org/10.1371/journal.pmed.1003702

Closing the health equity gap: A role for implementation science?

Beryne Odeny

PLOS Medicine: published September 14, 2021 | https://doi.org/10.1371/journal.pmed.1003762

Policy Forum

Future directions for HIV service delivery research: Research gaps identified through WHO guideline development

Nathan Ford, Ingrid Eshun-Wilson, Wole Ameyan, Morkor Newman, Lara Vojnov, Meg Doherty, Elvin Geng

PLOS Medicine: published September 23, 2021 | https://doi.org/10.1371/journal.pmed.1003812

Guidelines and Guidance

Social Innovation For Health Research: Development of the SIFHR Checklist

Eneyi E. Kpokiri, Elizabeth Chen, Jingjing Li, Sarah Payne, Priyanka Shrestha, Kaosar Afsana, Uche Amazigo, Phyllis Awor, Jean-Francois de Lavison, Saqif Khan, Jana Mier-Alpaño, Alberto Ong Jr, Shivani Subhedar, Isabelle Wachmuth, Luis Gabriel Cuervo, Kala M. Mehta, Beatrice Halpaap, Joseph D. Tucker

PLOS Medicine: published September 13, 2021 | https://doi.org/10.1371/journal.pmed.1003788

Collection Review

Evaluation of portable devices for medicine quality screening: Lessons learnt, recommendations for implementation, and future priorities

Céline Caillet, Serena Vickers, Vayouly Vidhamaly, Kem Boutsamay, Phonepasith Boupha, Stephen Zambrzycki, Nantasit Luangasanatip, Yoel Lubell, Facundo M. Fernández, Paul N. Newton

PLOS Medicine: published September 30, 2021 | https://doi.org/10.1371/journal.pmed.1003747

Research Articles

Corporate political activity in the context of unhealthy food advertising restrictions across Transport for London: A qualitative case study

Kathrin Lauber, Daniel Hunt, Anna B. Gilmore, Harry Rutter

PLOS Medicine: published September 2, 2021 | https://doi.org/10.1371/journal.pmed.1003695

Changes in maternal risk factors and their association with changes in cesarean sections in Norway between 1999 and 2016: A descriptive population-based registry study

Ingvild Hersoug Nedberg, Marzia Lazzerini, Ilaria Mariani, Kajsa Møllersen, Emanuelle Pessa Valente, Erik Eik Anda, Finn Egil Skjeldestad

PLOS Medicine: published September 3, 2021 | https://doi.org/10.1371/journal.pmed.1003764

The latent tuberculosis cascade-of-care among people living with HIV: A systematic review and meta-analysis

Mayara Lisboa Bastos, Luca Melnychuk, Jonathon R. Campbell, Olivia Oxlade, Dick Menzies

PLOS Medicine: published September 7, 2021 | https://doi.org/10.1371/journal.pmed.1003703

Cardiovascular disease, obesity, and type 2 diabetes in children born after assisted reproductive technology: A population-based cohort study

Emma Norrman, Max Petzold, Mika Gissler, Anne Lærke Spangmose, Signe Opdahl, Anna-Karina Henningsen, Anja Pinborg, Aila Tiitinen, Annika Rosengren, Liv Bente Romundstad, Ulla-Britt Wennerholm, Christina Bergh

PLOS Medicine: published September 7, 2021 | https://doi.org/10.1371/journal.pmed.1003723

Altering product placement to create a healthier layout in supermarkets: Outcomes on store sales, customer purchasing, and diet in a prospective matched controlled cluster study

Christina Vogel, Sarah Crozier, Daniel Penn-Newman, Kylie Ball, Graham Moon, Joanne Lord, Cyrus Cooper, Janis Baird

PLOS Medicine: published September 7, 2021 | https://doi.org/10.1371/journal.pmed.1003729

Derivation and external validation of a risk score for predicting HIV-associated tuberculosis to support case finding and preventive therapy scale-up: A cohort study

Andrew F. Auld, Andrew D. Kerkhoff, Yasmeen Hanifa, Robin Wood, Salome Charalambous, Yuliang Liu, Tefera Agizew, Anikie Mathoma, Rosanna Boyd, Anand Date, Ray W. Shiraishi, George Bicego, Unami Mathebula-Modongo, Heather Alexander, Christopher Serumola, Goabaone Rankgoane-Pono, Pontsho Pono, Alyssa Finlay, James C. Shepherd, Tedd V. Ellerbrock, Alison D. Grant, Katherine Fielding

PLOS Medicine: published September 7, 2021 | https://doi.org/10.1371/journal.pmed.1003739

The cardiovascular effects of amodiaquine and structurally related antimalarials: An individual patient data meta-analysis

Xin Hui S. Chan, Ilsa L. Haeusler, Yan Naung Win, James Pike, Borimas Hanboonkunupakarn, Maryam Hanafiah, Sue J. Lee, Abdoulaye Djimdé, Caterina I. Fanello, Jean-René Kiechel, Marcus VG Lacerda, Bernhards Ogutu, Marie A. Onyamboko, André M. Siqueira, Elizabeth A. Ashley, Walter RJ Taylor, Nicholas J. White

PLOS Medicine: published September 7, 2021 | https://doi.org/10.1371/journal.pmed.1003766

Effectiveness of seasonal malaria chemoprevention (SMC) treatments when SMC is implemented at scale: Case–control studies in 5 countries

Matthew Cairns, Serign Jawo Ceesay, Issaka Sagara, Issaka Zongo, Hamit Kessely, Kadidja Gamougam, Abdoulaye Diallo, Johnbull Sonny Ogboi, Diego Moroso, Suzanne Van Hulle, Tony Eloike, Paul Snell, Susana Scott, Corinne Merle, Kalifa Bojang, Jean Bosco Ouedraogo, Alassane Dicko, Jean-Louis Ndiaye, Paul Milligan

PLOS Medicine: published September 8, 2021 | https://doi.org/10.1371/journal.pmed.1003727

Infections in temporal proximity to HPV vaccination and adverse effects following vaccination in Denmark: A nationwide register-based cohort study and case-crossover analysis

Lene Wulff Krogsgaard, Irene Petersen, Oleguer Plana-Ripoll, Bodil Hammer Bech, Tina Hovgaard Lützen, Reimar Wernich Thomsen, Dorte Rytter

PLOS Medicine: published September 8, 2021 | https://doi.org/10.1371/journal.pmed.1003768

Body muscle gain and markers of cardiovascular disease susceptibility in young adulthood: A cohort study

Joshua A. Bell, Kaitlin H. Wade, Linda M. O’Keeffe, David Carslake, Emma E. Vincent, Michael V. Holmes, Nicholas J. Timpson, George Davey Smith

PLOS Medicine: published September 9, 2021 | https://doi.org/10.1371/journal.pmed.1003751

Computer-aided X-ray screening for tuberculosis and HIV testing among adults with cough in Malawi (the PROSPECT study): A randomised trial and cost-effectiveness analysis

Peter MacPherson, Emily L. Webb, Wala Kamchedzera, Elizabeth Joekes, Gugu Mjoli, David G. Lalloo, Titus H. Divala, Augustine T. Choko, Rachael M. Burke, Hendramoorthy Maheswaran, Madhukar Pai, S. Bertel Squire, Marriott Nliwasa, Elizabeth L. Corbett

PLOS Medicine: published September 9, 2021 | https://doi.org/10.1371/journal.pmed.1003752

Intrinsic capacity and its associations with incident dependence and mortality in 10/66 Dementia Research Group studies in Latin America, India, and China: A population-based cohort study

Martin J. Prince, Daisy Acosta, Mariella Guerra, Yueqin Huang, K. S. Jacob, Ivonne Z. Jimenez-Velazquez, A. T. Jotheeswaran, Juan J. Llibre Rodriguez, Aquiles Salas, Ana Luisa Sosa, Isaac Acosta, Rosie Mayston, Zhaorui Liu, Jorge J. Llibre-Guerra, A. Matthew Prina, Adolfo Valhuerdi

PLOS Medicine: published September 14, 2021 | https://doi.org/10.1371/journal.pmed.1003097

Economic and modeling evidence for tuberculosis preventive therapy among people living with HIV: A systematic review and meta-analysis

Aashna Uppal, Samiha Rahman, Jonathon R. Campbell, Olivia Oxlade, Dick Menzies

PLOS Medicine: published September 14, 2021 | https://doi.org/10.1371/journal.pmed.1003712

Tuberculosis preventive therapy for people living with HIV: A systematic review and network meta-analysis

Mercedes Yanes-Lane, Edgar Ortiz-Brizuela, Jonathon R. Campbell, Andrea Benedetti, Gavin Churchyard, Olivia Oxlade, Dick Menzies

PLOS Medicine: published September 14, 2021 | https://doi.org/10.1371/journal.pmed.1003738

Impact of decreasing the proportion of higher energy foods and reducing portion sizes on food purchased in worksite cafeterias: A stepped-wedge randomised controlled trial

James P. Reynolds, Minna Ventsel, Daina Kosīte, Brier Rigby Dames, Laura Brocklebank, Sarah Masterton, Emily Pechey, Mark Pilling, Rachel Pechey, Gareth J. Hollands, Theresa M. Marteau

PLOS Medicine: published September 14, 2021 | https://doi.org/10.1371/journal.pmed.1003743

Evaluating the frequency of English language requirements in clinical trial eligibility criteria: A systematic analysis using ClinicalTrials.gov

Akila V. Muthukumar, Walker Morrell, Barbara E. Bierer

PLOS Medicine: published September 14, 2021 | https://doi.org/10.1371/journal.pmed.1003758

The burden of traumatic brain injury from low-energy falls among patients from 18 countries in the CENTER-TBI Registry: A comparative cohort study

Fiona E. Lecky, Olubukola Otesile, Carl Marincowitz, Marek Majdan, Daan Nieboer, Hester F. Lingsma, Marc Maegele, Giuseppe Citerio, Nino Stocchetti, Ewout W. Steyerberg, David K. Menon, Andrew I. R. Maas, CENTER-TBI Participants and Investigators

PLOS Medicine: published September 14, 2021 | https://doi.org/10.1371/journal.pmed.1003761

Socioeconomic inequalities in prevalence and development of multimorbidity across adulthood: A longitudinal analysis of the MRC 1946 National Survey of Health and Development in the UK

Amal R. Khanolkar, Nishi Chaturvedi, Valerie Kuan, Daniel Davis, Alun Hughes, Marcus Richards, David Bann, Praveetha Patalay

PLOS Medicine: published September 14, 2021 | https://doi.org/10.1371/journal.pmed.1003775

Association of physical activity intensity and bout length with mortality: An observational study of 79,503 UK Biobank participants

Louise A. C. Millard, Kate Tilling, Tom R. Gaunt, David Carslake, Deborah A. Lawlor

PLOS Medicine: published September 15, 2021 | https://doi.org/10.1371/journal.pmed.1003757

Associations between women’s empowerment and child development, growth, and nurturing care practices in sub-Saharan Africa: A cross-sectional analysis of demographic and health survey data

Lilia Bliznashka, Ifeyinwa E. Udo, Christopher R. Sudfeld, Wafaie W. Fawzi, Aisha K. Yousafzai

PLOS Medicine: published September 16, 2021 | https://doi.org/10.1371/journal.pmed.1003781

Community-facility linkage models and maternal and infant health outcomes in Malawi’s PMTCT/ART program: A cohort study

Michael E. Herce, Maganizo B. Chagomerana, Lauren C. Zalla, Nicole B. Carbone, Benjamin H. Chi, Michael T. Eliya, Sam Phiri, Stephanie M. Topp, Maria H. Kim, Emily B. Wroe, Chileshe Chilangwa, Jacqueline Chinkonde, Innocent A. Mofolo, Mina C. Hosseinipour, Jessie K. Edwards

PLOS Medicine: published September 17, 2021 | https://doi.org/10.1371/journal.pmed.1003780

All-cause and cause-specific mortality during and following incarceration in Brazil: A retrospective cohort study

Yiran E. Liu, Everton Ferreira Lemos, Crhistinne Cavalheiro Maymone Gonçalves, Roberto Dias de Oliveira, Andrea da Silva Santos, Agne Oliveira do Prado Morais, Mariana Garcia Croda, Maria de Lourdes Delgado Alves, Julio Croda, Katharine S. Walter, Jason R. Andrews

PLOS Medicine: published September 17, 2021 | https://doi.org/10.1371/journal.pmed.1003789

Differences in outcomes of mandatory motorcycle helmet legislation by country income level: A systematic review and meta-analysis

Jacob R. Lepard, Riccardo Spagiari, Jacquelyn Corley, Ernest J. Barthélemy, Eliana Kim, Rolvix Patterson, Sara Venturini, Megan E. H. Still, Yu Tung Lo, Gail Rosseau, Rania A. Mekary, Kee B. Park

PLOS Medicine: published September 17, 2021 | https://doi.org/10.1371/journal.pmed.1003795

The blood metabolome of incident kidney cancer: A case–control study nested within the MetKid consortium

Florence Guida, Vanessa Y. Tan, Laura J. Corbin, Karl Smith-Byrne, Karine Alcala, Claudia Langenberg, Isobel D. Stewart, Adam S. Butterworth, Praveen Surendran, David Achaintre, Jerzy Adamski, Pilar Amiano, Manuela M. Bergmann, Caroline J. Bull, Christina C. Dahm, Audrey Gicquiau, Graham G. Giles, Marc J. Gunter, Toomas Haller, Arnulf Langhammer, Tricia L. Larose, Börje Ljungberg, Andres Metspalu, Roger L. Milne, David C. Muller, Therese H. Nøst, Elin Pettersen Sørgjerd, Cornelia Prehn, Elio Riboli, Sabina Rinaldi, Joseph A. Rothwell, Augustin Scalbert, Julie A. Schmidt, Gianluca Severi, Sabina Sieri, Roel Vermeulen, Emma E. Vincent, Melanie Waldenberger, Nicholas J. Timpson, Mattias Johansson

PLOS Medicine: published September 20, 2021 | https://doi.org/10.1371/journal.pmed.1003786

Effect of a patient-centered hypertension delivery strategy on all-cause mortality: Secondary analysis of SEARCH, a community-randomized trial in rural Kenya and Uganda

Matthew D. Hickey, James Ayieko, Asiphas Owaraganise, Nicholas Sim, Laura B. Balzer, Jane Kabami, Mucunguzi Atukunda, Fredrick J. Opel, Erick Wafula, Marilyn Nyabuti, Lillian Brown, Gabriel Chamie, Vivek Jain, James Peng, Dalsone Kwarisiima, Carol S. Camlin, Edwin D. Charlebois, Craig R. Cohen, Elizabeth A. Bukusi, Moses R. Kamya, Maya L. Petersen, Diane V. Havlir

PLOS Medicine: published September 20, 2021 | https://doi.org/10.1371/journal.pmed.1003803

Evaluation of an mHealth-enabled hierarchical diabetes management intervention in primary care in China (ROADMAP): A cluster randomized trial

Weiping Jia, Puhong Zhang, Dalong Zhu, Nadila Duolikun, Hong Li, Yuqian Bao, Xian Li, for the ROADMAP Study Group

PLOS Medicine: published September 21, 2021 | https://doi.org/10.1371/journal.pmed.1003754

Biomarkers of dairy fat intake, incident cardiovascular disease, and all-cause mortality: A cohort study, systematic review, and meta-analysis

Kathy Trieu, Saiuj Bhat, Zhaoli Dai, Karin Leander, Bruna Gigante, Frank Qian, Andres V. Ardisson Korat, Qi Sun, Xiong-Fei Pan, Federica Laguzzi, Tommy Cederholm, Ulf de Faire, Mai-Lis Hellénius, Jason H. Y. Wu, Ulf Risérus, Matti Marklund

PLOS Medicine: published September 21, 2021 | https://doi.org/10.1371/journal.pmed.1003763

Prevalence and incidence of young onset dementia and associations with comorbidities: A study of data from the French national health data system

Laure Carcaillon-Bentata, Cécile Quintin, Marjorie Boussac-Zarebska, Alexis Elbaz

PLOS Medicine: published September 23, 2021 | https://doi.org/10.1371/journal.pmed.1003801

Relative risks of adverse events among older adults receiving opioids versus NSAIDs after hospital discharge: A nationwide cohort study

Shoshana J. Herzig, Timothy S. Anderson, Yoojin Jung, Long Ngo, Dae H. Kim, Ellen P. McCarthy

PLOS Medicine: published September 27, 2021 | https://doi.org/10.1371/journal.pmed.1003804

Conditional cash transfer program and child mortality: A cross-sectional analysis nested within the 100 Million Brazilian Cohort

Dandara Ramos, Nívea B. da Silva, Maria Yury Ichihara, Rosemeire L. Fiaccone, Daniela Almeida, Samila Sena, Poliana Rebouças, Elzo Pereira Pinto Júnior, Enny S. Paixão, Sanni Ali, Laura C. Rodrigues, Maurício L. Barreto

PLOS Medicine: published September 28, 2021 | https://doi.org/10.1371/journal.pmed.1003509

Effect of scheduled antimicrobial and nicotinamide treatment on linear growth in children in rural Tanzania: A factorial randomized, double-blind, placebo-controlled trial

Mark D. DeBoer, James A. Platts-Mills, Sarah E. Elwood, Rebecca J. Scharf, Joann M. McDermid, Anne W. Wanjuhi, Samwel Jatosh, Siphael Katengu, Tarina C. Parpia, Elizabeth T. Rogawski McQuade, Jean Gratz, Erling Svensen, Jonathan R. Swann, Jeffrey R. Donowitz, Paschal Mdoe, Sokoine Kivuyo, Eric R. Houpt, Estomih Mduma

PLOS Medicine: published September 28, 2021 | https://doi.org/10.1371/journal.pmed.1003617

A novel intervention combining supplementary food and infection control measures to improve birth outcomes in undernourished pregnant women in Sierra Leone: A randomized, controlled clinical effectiveness trial

David Taylor Hendrixson, Kristie Smith, Patrick Lasowski, Meghan Callaghan-Gillespie, Jacklyn Weber, Peggy Papathakis, Per Ole Iversen, Aminata Shamit Koroma, Mark J. Manary

PLOS Medicine: published September 28, 2021 | https://doi.org/10.1371/journal.pmed.1003618

Gender-equitable caregiver attitudes and education and safety of adolescent girls in South Kivu, DRC: A secondary analysis from a randomized controlled trial

Ilana Seff, Kathryn Falb, Gary Yu, Debbie Landis, Lindsay Stark

PLOS Medicine: published September 28, 2021 | https://doi.org/10.1371/journal.pmed.1003619

Drought and child vaccination coverage in 22 countries in sub-Saharan Africa: A retrospective analysis of national survey data from 2011 to 2019

Jason M. Nagata, Adrienne Epstein, Kyle T. Ganson, Tarik Benmarhnia, Sheri D. Weiser

PLOS Medicine: published September 28, 2021 | https://doi.org/10.1371/journal.pmed.1003678

Effect of sunflower seed oil emollient therapy on newborn infant survival in Uttar Pradesh, India: A community-based, cluster randomized, open-label controlled trial

Aarti Kumar, Shambhavi Mishra, Shambhavi Singh, Sana Ashraf, Peiyi Kan, Amit Kumar Ghosh, Alok Kumar, Raghav Krishna, David K. Stevenson, Lu Tian, Peter M. Elias, Gary L. Darmstadt, Vishwajeet Kumar, for the Shivgarh Emollient Research Group

PLOS Medicine: published September 28, 2021 | https://doi.org/10.1371/journal.pmed.1003680

Severe bacterial neonatal infections in Madagascar, Senegal, and Cambodia: A multicentric community-based cohort study

Bich-Tram Huynh, Elsa Kermorvant-Duchemin, Rattanak Chheang, Frederique Randrianirina, Abdoulaye Seck, Elisoa Hariniaina Ratsima, Zafitsara Zo Andrianirina, Jean-Baptiste Diouf, Armya Youssouf Abdou, Sophie Goyet, Véronique Ngo, Siyin Lach, Long Pring, Touch Sok, Michael Padget, Fatoumata Diene Sarr, Laurence Borand, Benoit Garin, Jean-Marc Collard, Perlinot Herindrainy, Agathe de Lauzanne, Muriel Vray, Elisabeth Delarocque-Astagneau, Didier Guillemot, On behalf of the BIRDY study group

PLOS Medicine: published September 28, 2021 | https://doi.org/10.1371/journal.pmed.1003681

Exposure to conflicts and the continuum of maternal healthcare: Analyses of pooled cross-sectional data for 452,192 women across 49 countries and 82 surveys

Anu Rammohan, Astghik Mavisakalyan, Loan Vu, Srinivas Goli

PLOS Medicine: published September 28, 2021 | https://doi.org/10.1371/journal.pmed.1003690

Effectiveness of cash-plus programmes on early childhood outcomes compared to cash transfers alone: A systematic review and meta-analysis in low- and middle-income countries

Madison T. Little, Keetie Roelen, Brittany C. L. Lange, Janina I. Steinert, Alexa R. Yakubovich, Lucie Cluver, David K. Humphreys

PLOS Medicine: published September 28, 2021 | https://doi.org/10.1371/journal.pmed.1003698

Neurocognitive outcomes in Malawian children exposed to malaria during pregnancy: An observational birth cohort study

Andrea M. Weckman, Andrea L. Conroy, Mwayiwawo Madanitsa, Bruno Gnaneswaran, Chloe R. McDonald, Linda Kalilani-Phiri, Jaya Chandna, Doreen Ali, Victor Mwapasa, Carole Khairallah, Kyaw Lay Thwai, Steven R. Meshnick, Steve M. Taylor, Feiko O. ter Kuile, Kevin C. Kain, Melissa Gladstone

PLOS Medicine: published September 28, 2021 | https://doi.org/10.1371/journal.pmed.1003701

Ambient and household PM_2.5 pollution and adverse perinatal outcomes: A meta-regression and analysis of attributable global burden for 204 countries and territories

Rakesh Ghosh, Kate Causey, Katrin Burkart, Sara Wozniak, Aaron Cohen, Michael Brauer

PLOS Medicine: published September 28, 2021 | https://doi.org/10.1371/journal.pmed.1003718

The relationship between psychosocial circumstances and injuries in adolescents: An analysis of 87,269 individuals from 26 countries using the Global School-based Student Health Survey

Samiha Ismail, Maria Lisa Odland, Amman Malik, Misghina Weldegiorgis, Karen Newbigging, Margaret Peden, Mark Woodward, Justine Davies

PLOS Medicine: published September 28, 2021 | https://doi.org/10.1371/journal.pmed.1003722

Evaluation of a community-based mobile video breastfeeding intervention in Khayelitsha, South Africa: The Philani MOVIE cluster-randomized controlled trial

Maya Adam, Jamie Johnston, Nophiwe Job, Mithilesh Dronavalli, Ingrid Le Roux, Nokwanele Mbewu, Neliswa Mkunqwana, Mark Tomlinson, Shannon A. McMahon, Amnesty E. LeFevre, Alain Vandormael, Kira-Leigh Kuhnert, Pooja Suri, Jennifer Gates, Bongekile Mabaso, Aarti Porwal, Charles Prober, Till Bärnighausen

PLOS Medicine: published September 28, 2021 | https://doi.org/10.1371/journal.pmed.1003744

Examining the relationships between early childhood experiences and adolescent and young adult health status in a resource-limited population: A cohort study

Zeba A. Rasmussen, Wasiat H. Shah, Chelsea L. Hansen, Syed Iqbal Azam, Ejaz Hussain, Barbara A. Schaefer, Nicole Zhong, Alexandra F. Jamison, Khalil Ahmed, Benjamin J. J. McCormick, for the Oshikhandass Water, Sanitation, Health and Hygiene Interventions Project

PLOS Medicine: published September 28, 2021 | https://doi.org/10.1371/journal.pmed.1003745

Cost-effectiveness and economic returns of group-based parenting interventions to promote early childhood development: Results from a randomized controlled trial in rural Kenya

Italo Lopez Garcia, Uzaib Y. Saya, Jill E. Luoto

PLOS Medicine: published September 28, 2021 | https://doi.org/10.1371/journal.pmed.1003746

Factors associated with the prevalence of HIV, HSV-2, pregnancy, and reported sexual activity among adolescent girls in rural western Kenya: A cross-sectional analysis of baseline data in a cluster randomized controlled trial

Garazi Zulaika, Elizabeth Nyothach, Anna Maria van Eijk, David Obor, Linda Mason, Duolao Wang, Tao Chen, Emily Kerubo, Valarie Opollo, Isaac Ngere, Samuel Omondi Owino, Boaz Oyaro, Feiko O. ter Kuile, Daniel Kwaro, Penelope Phillips-Howard

PLOS Medicine: published September 28, 2021 | https://doi.org/10.1371/journal.pmed.1003756

Regional differences in short stature in England between 2006 and 2019: A cross-sectional analysis from the National Child Measurement Programme

Joanna Orr, Joseph Freer, Joan K. Morris, Caroline Hancock, Robert Walton, Leo Dunkel, Helen L. Storr, Andrew J. Prendergast

PLOS Medicine: published September 28, 2021 | https://doi.org/10.1371/journal.pmed.1003760

Incidence, co-occurrence, and evolution of long-COVID features: A 6-month retrospective cohort study of 273,618 survivors of COVID-19

Maxime Taquet, Quentin Dercon, Sierra Luciano, John R. Geddes, Masud Husain, Paul J. Harrison

PLOS Medicine: published September 28, 2021 | https://doi.org/10.1371/journal.pmed.1003773

Predictive symptoms for COVID-19 in the community: REACT-1 study of over 1 million people

Joshua Elliott, Matthew Whitaker, Barbara Bodinier, Oliver Eales, Steven Riley, Helen Ward, Graham Cooke, Ara Darzi, Marc Chadeau-Hyam, Paul Elliott

PLOS Medicine: published September 28, 2021 | https://doi.org/10.1371/journal.pmed.1003777

Effectiveness and costs associated with a lay counselor–delivered, brief problem-solving mental health intervention for adolescents in urban, low-income schools in India: 12-month outcomes of a randomized controlled trial

Kanika Malik, Daniel Michelson, Aoife M. Doyle, Helen A. Weiss, Giulia Greco, Rooplata Sahu, James E. J., Sonal Mathur, Paulomi Sudhir, Michael King, Pim Cuijpers, Bruce Chorpita, Christopher G. Fairburn, Vikram Patel

PLOS Medicine: published September 28, 2021 | https://doi.org/10.1371/journal.pmed.1003778

Gram-negative neonatal sepsis in low- and lower-middle-income countries and WHO empirical antibiotic recommendations: A systematic review and meta-analysis

Sophie C. H. Wen, Yukiko Ezure, Lauren Rolley, Geoff Spurling, Colleen L. Lau, Saba Riaz, David L. Paterson, Adam D. Irwin

PLOS Medicine: published September 28, 2021 | https://doi.org/10.1371/journal.pmed.1003787

Maternal hypertensive disorder of pregnancy and offspring early-onset cardiovascular disease in childhood, adolescence, and young adulthood: A national population-based cohort study

Chen Huang, Jiong Li, Guoyou Qin, Zeyan Liew, Jing Hu, Krisztina D. László, Fangbiao Tao, Carsten Obel, Jørn Olsen, Yongfu Yu

PLOS Medicine: published September 28, 2021 | https://doi.org/10.1371/journal.pmed.1003805

Implications of armed conflict for maternal and child health: A regression analysis of data from 181 countries for 2000–2019

Mohammed Jawad, Thomas Hone, Eszter P. Vamos, Valeria Cetorelli, Christopher Millett

PLOS Medicine: published September 28, 2021 | https://doi.org/10.1371/journal.pmed.1003810

Death of an offspring and parental risk of ischemic heart diseases: A population-based cohort study

Dang Wei, Imre Janszky, Fang Fang, Hua Chen, Rickard Ljung, Jiangwei Sun, Jiong Li, Krisztina D. László

PLOS Medicine: published September 29, 2021 | https://doi.org/10.1371/journal.pmed.1003790

Postmortem investigations and identification of multiple causes of child deaths: An analysis of findings from the Child Health and Mortality Prevention Surveillance (CHAMPS) network

Robert F. Breiman, Dianna M. Blau, Portia Mutevedzi, Victor Akelo, Inacio Mandomando, Ikechukwu U. Ogbuanu, Samba O. Sow, Lola Madrid, Shams El Arifeen, Mischka Garel, Nana Bukiwe Thwala, Dickens Onyango, Antonio Sitoe, Ima-Abasi Bassey, Adama Mamby Keita, Addisu Alemu, Muntasir Alam, Sana Mahtab, Dickson Gethi, Rosauro Varo, Julius Ojulong, Solomon Samura, Ashka Mehta, Alexander M. Ibrahim, Afruna Rahman, Pio Vitorino, Vicky L. Baillie, Janet Agaya, Milagritos D. Tapia, Nega Assefa, Atique Iqbal Chowdhury, J. Anthony G. Scott, Emily S. Gurley, Karen L. Kotloff, Amara Jambai, Quique Bassat, Beth A. Tippett-Barr, Shabir A. Madhi, Cynthia G. Whitney, the CHAMPS Consortium

PLOS Medicine: published September 30, 2021 | https://doi.org/10.1371/journal.pmed.1003814

Corrections

Correction: Bone marrow microenvironments that contribute to patient outcomes in newly diagnosed multiple myeloma: A cohort study of patients in the Total Therapy clinical trials

The PLOS Medicine Staff

PLOS Medicine: published September 8, 2021 | https://doi.org/10.1371/journal.pmed.1003774

Correction: Associations of obesity and malnutrition with cardiac remodeling and cardiovascular outcomes in Asian adults: A cohort study

Shih-Chieh Chien, Chanchal Chandramouli, Chi-In Lo, Chao-Feng Lin, Kuo-Tzu Sung, Wen-Hung Huang, Yau-Huei Lai, Chun-Ho Yun, Cheng Huang, Hung-I Yeh, Ta-Chuan Hung, Chung-Lieh Hung, Carolyn S. P. Lam

PLOS Medicine: published September 13, 2021 | https://doi.org/10.1371/journal.pmed.1003784

Correction: Benefit and harm of intensive blood pressure treatment: Derivation and validation of risk models using data from the SPRINT and ACCORD trials

Sanjay Basu, Jeremy B. Sussman, Joseph Rigdon, Lauren Steimle, Brian T. Denton, Rodney A. Hayward

PLOS Medicine: published September 16, 2021 | https://doi.org/10.1371/journal.pmed.1003785

Correction: Accelerometer measured physical activity and the incidence of cardiovascular disease: Evidence from the UK Biobank cohort study

Rema Ramakrishnan, Aiden Doherty, Karl Smith-Byrne, Kazem Rahimi, Derrick Bennett, Mark Woodward, Rosemary Walmsley, Terence Dwyer

PLOS Medicine: published September 29, 2021 | https://doi.org/10.1371/journal.pmed.1003809

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