The G protein alpha chaperone and guanine-nucleotide exchange factor RIC-8 regulates cilia morphogenesis in Caenorhabditis elegans sensory neurons

Christina M. Campagna, Hayley McMahon, Inna Nechipurenko

PLOS Genetics: published November 1, 2023 | https://doi.org/10.1371/journal.pgen.1011015

A disease associated mutant reveals how Ltv1 orchestrates RP assembly and rRNA folding of the small ribosomal subunit head

Ebba K. Blomqvist, Haina Huang, Katrin Karbstein

PLOS Genetics: published November 1, 2023 | https://doi.org/10.1371/journal.pgen.1010862

Deletions of singular U1 snRNA gene significantly interfere with transcription and 3’-end mRNA formation

Mei Wang, An-Min Liang, Zhen-Zhen Zhou, Ting-Lin Pang, Yu-Jie Fan, Yong-Zhen Xu

PLOS Genetics: published November 2, 2023 | https://doi.org/10.1371/journal.pgen.1011021

Central metabolism is a key player in E. coli biofilm stimulation by sub-MIC antibiotics

Luke N. Yaeger, Shawn French, Eric D. Brown, Jean Philippe Côté, Lori L. Burrows

PLOS Genetics: published November 2, 2023 | https://doi.org/10.1371/journal.pgen.1011013

Genome instability footprint under rapamycin and hydroxyurea treatments

Jing Li, Simon Stenberg, Jia-Xing Yue, Ekaterina Mikhalev, Dawn Thompson, Jonas Warringer, Gianni Liti

PLOS Genetics: published November 6, 2023 | https://doi.org/10.1371/journal.pgen.1011012

PGP-14 establishes a polar lipid permeability barrier within the C. elegans pharyngeal cuticle

Muntasir Kamal, Levon Tokmakjian, Jessica Knox, Duhyun Han, Houtan Moshiri, Lilia Magomedova, Ken CQ Nguyen, Hong Zheng, Andrew R. Burns, Brittany Cooke, Jessica Lacoste, May Yeo, David H. Hall, Carolyn L. Cummins, Peter J. Roy

PLOS Genetics: published November 6, 2023 | https://doi.org/10.1371/journal.pgen.1011008

Her6 and Prox1a are novel regulators of photoreceptor regeneration in the zebrafish retina

Kellie Veen, Aaron Krylov, Shuguang Yu, Jie He, Patrick Boyd, David R. Hyde, Theo Mantamadiotis, Louise Y. Cheng, Patricia R. Jusuf

PLOS Genetics: published November 6, 2023 | https://doi.org/10.1371/journal.pgen.1011010

Dominant negative variants in KIF5B cause osteogenesis imperfecta via down regulation of mTOR signaling

Ronit Marom, Bo Zhang, Megan E. Washington, I-Wen Song, Lindsay C. Burrage, Vittoria C. Rossi, Ava S. Berrier, Anika Lindsey, Jacob Lesinski, Michael L. Nonet, Jian Chen, Dustin Baldridge, Gary A. Silverman, V. Reid Sutton, Jill A. Rosenfeld, Alyssa A. Tran, M. John Hicks, David R. Murdock, Hongzheng Dai, MaryAnn Weis, Shalini N. Jhangiani, Donna M. Muzny, Richard A. Gibbs, Richard Caswell, Carrie Pottinger, Deirdre Cilliers, Karen Stals, Undiagnosed Diseases Network, David Eyre, Deborah Krakow, Tim Schedl, Stephen C. Pak, Brendan H. Lee

PLOS Genetics: published November 7, 2023 | https://doi.org/10.1371/journal.pgen.1011005

Domain-adaptive neural networks improve supervised machine learning based on simulated population genetic data

Ziyi Mo, Adam Siepel

PLOS Genetics: published November 7, 2023 | https://doi.org/10.1371/journal.pgen.1011032

Lineage-specific genes are clustered with HET-domain genes and respond to environmental and genetic manipulations regulating reproduction in Neurospora

Zheng Wang, Yen-Wen Wang, Takao Kasuga, Francesc Lopez-Giraldez, Yang Zhang, Zhang Zhang, Yaning Wang, Caihong Dong, Anita Sil, Frances Trail, Oded Yarden, Jeffrey P. Townsend

PLOS Genetics: published November 7, 2023 | https://doi.org/10.1371/journal.pgen.1011019

Methods for mediation analysis with high-dimensional DNA methylation data: Possible choices and comparisons

Dylan Clark-Boucher, Xiang Zhou, Jiacong Du, Yongmei Liu, Belinda L. Needham, Jennifer A. Smith, Bhramar Mukherjee

PLOS Genetics: published November 7, 2023 | https://doi.org/10.1371/journal.pgen.1011022

Spt5 C-terminal repeat domain phosphorylation and length negatively regulate heterochromatin through distinct mechanisms

Sarah MacKinnon, Viviane Pagé, Jennifer J. Chen, Ali Shariat-Panahi, Ryan D. Martin, Terence E. Hébert, Jason C. Tanny

PLOS Genetics: published November 8, 2023 | https://doi.org/10.1371/journal.pgen.1010492

Context-dependent ciliary regulation of hedgehog pathway repression in tissue morphogenesis

Sun-Hee Hwang, Kevin Andrew White, Bandarigoda Nipunika Somatilaka, Baolin Wang, Saikat Mukhopadhyay

PLOS Genetics: published November 9, 2023 | https://doi.org/10.1371/journal.pgen.1011028

Coordination of Pickpocket ion channel delivery and dendrite growth in Drosophila sensory neurons

Josephine W. Mitchell, Ipek Midillioglu, Ethan Schauer, Bei Wang, Chun Han, Jill Wildonger

PLOS Genetics: published November 9, 2023 | https://doi.org/10.1371/journal.pgen.1011025

Exportin-mediated nucleocytoplasmic transport maintains Pch2 homeostasis during meiosis

Esther Herruzo, Estefanía Sánchez-Díaz, Sara González-Arranz, Beatriz Santos, Jesús A. Carballo, Pedro A. San-Segundo

PLOS Genetics: published November 10, 2023 | https://doi.org/10.1371/journal.pgen.1011026

RET enhancer haplotype-dependent remodeling of the human fetal gut development program

Sumantra Chatterjee, Lauren E. Fries, Or Yaacov, Nan Hu, Hanna E. Berk-Rauch, Aravinda Chakravarti

PLOS Genetics: published November 10, 2023 | https://doi.org/10.1371/journal.pgen.1011030

MIWI N-terminal RG motif promotes efficient pachytene piRNA production and spermatogenesis independent of LINE1 transposon silencing

Chao Wei, Jiongjie Jing, Xiaoyuan Yan, Jeffrey M. Mann, Ruirong Geng, Huirong Xie, Elena Y. Demireva, Rex A. Hess, Deqiang Ding, Chen Chen

PLOS Genetics: published November 13, 2023 | https://doi.org/10.1371/journal.pgen.1011031

Checkpoint phosphorylation sites on budding yeast Rif1 protect nascent DNA from degradation by Sgs1-Dna2

Vamsi Krishna Gali, Chandre Monerawela, Yassine Laksir, Shin-ichiro Hiraga, Anne D. Donaldson

PLOS Genetics: published November 13, 2023 | https://doi.org/10.1371/journal.pgen.1011044

Genome mining yields putative disease-associated ROMK variants with distinct defects

Nga H. Nguyen, Srikant Sarangi, Erin M. McChesney, Shaohu Sheng, Jacob D. Durrant, Aidan W. Porter, Thomas R. Kleyman, Zachary W. Pitluk, Jeffrey L. Brodsky

PLOS Genetics: published November 13, 2023 | https://doi.org/10.1371/journal.pgen.1011051

Cross-ancestry analyses identify new genetic loci associated with 25-hydroxyvitamin D

Xiaotong Wang, Valentin Hivert, Shiane Groot, Ying Wang, Loic Yengo, John J. McGrath, Kathryn E. Kemper, Peter M. Visscher, Naomi R. Wray, Joana A. Revez

PLOS Genetics: published November 14, 2023 | https://doi.org/10.1371/journal.pgen.1011033

The activity of engrailed imaginal disc enhancers is modulated epigenetically by chromatin and autoregulation

Yuzhong Cheng, Fountane Chan, Judith A. Kassis

PLOS Genetics: published November 15, 2023 | https://doi.org/10.1371/journal.pgen.1010826

XRE transcription factors conserved in Caulobacter and φCbK modulate adhesin development and phage production

Maeve McLaughlin, Aretha Fiebig, Sean Crosson

PLOS Genetics: published November 16, 2023 | https://doi.org/10.1371/journal.pgen.1011048

ZmEREB92 plays a negative role in seed germination by regulating ethylene signaling and starch mobilization in maize

Jingye Fu, Wenzheng Pei, Linqian He, Ben Ma, Chen Tang, Li Zhu, Liping Wang, Yuanyuan Zhong, Gang Chen, Qi Wang, Qiang Wang

PLOS Genetics: published November 17, 2023 | https://doi.org/10.1371/journal.pgen.1011052

Phosphorylation of AHR by PLK1 promotes metastasis of LUAD via DIO2-TH signaling

Chaohao Li, Derek B. Allison, Daheng He, Fengyi Mao, Xinyi Wang, Piotr Rychahou, Ibrahim A. Imam, Yifan Kong, Qiongsi Zhang, Yanquan Zhang, Jinghui Liu, Ruixin Wang, Xiongjian Rao, Sai Wu, B. Mark Evers, Qing Shao, Chi Wang, Zhiguo Li, Xiaoqi Liu

PLOS Genetics: published November 21, 2023 | https://doi.org/10.1371/journal.pgen.1011017

Accurate phenotypic classification and exome sequencing allow identification of novel genes and variants associated with adult-onset hearing loss

Morag A. Lewis, Jennifer Schulte, Lois Matthews, Kenneth I. Vaden Jr., Claire J. Steves, Frances M. K. Williams, Bradley A. Schulte, Judy R. Dubno, Karen P. Steel

PLOS Genetics: published November 27, 2023 | https://doi.org/10.1371/journal.pgen.1011058

Functional and evolutionary analysis of host Synaptogyrin-2 in porcine circovirus type 2 susceptibility

Lianna R. Walker, Hiep L. Vu, Kristi L. Montooth, Daniel C. Ciobanu

PLOS Genetics: published November 27, 2023 | https://doi.org/10.1371/journal.pgen.1011029

Spatial transcriptomics reveals novel genes during the remodelling of the embryonic human arterial valves

Rachel Queen, Moira Crosier, Lorraine Eley, Janet Kerwin, Jasmin E. Turner, Jianshi Yu, Ahlam Alqahtani, Tamilvendhan Dhanaseelan, Lynne Overman, Hannah Soetjoadi, Richard Baldock, Jonathan Coxhead, Veronika Boczonadi, Alex Laude, Simon J. Cockell, Maureen A. Kane, Steven Lisgo, Deborah J. Henderson

PLOS Genetics: published November 27, 2023 | https://doi.org/10.1371/journal.pgen.1010777

Expression, not sequence, distinguishes miR-238 from its miR-239ab sister miRNAs in promoting longevity in Caenorhabditis elegans

Laura B. Chipman, San Luc, Ian A. Nicastro, Jesse J. Hulahan, Delaney C. Dann, Devavrat M. Bodas, Amy E. Pasquinelli

PLOS Genetics: published November 27, 2023 | https://doi.org/10.1371/journal.pgen.1011055

Transfer learning with false negative control improves polygenic risk prediction

Xinge Jessie Jeng, Yifei Hu, Vaishnavi Venkat, Tzu-Pin Lu, Jung-Ying Tzeng

PLOS Genetics: published November 27, 2023 | https://doi.org/10.1371/journal.pgen.1010597

Efficient sex separation by exploiting differential alternative splicing of a dominant marker in Aedes aegypti

Shih-Che Weng, Igor Antoshechkin, Eric Marois, Omar S. Akbari

PLOS Genetics: published November 27, 2023 | https://doi.org/10.1371/journal.pgen.1011065

TGFß/activin-dependent activation of Torso controls the timing of the metamorphic transition in the red flour beetle Tribolium castaneum

Sílvia Chafino, Roser Salvia, Josefa Cruz, David Martín, Xavier Franch-Marro

PLOS Genetics: published November 27, 2023 | https://doi.org/10.1371/journal.pgen.1010897

Phosphate starvation decouples cell differentiation from DNA replication control in the dimorphic bacterium Caulobacter crescentus

Joel Hallgren, Kira Koonce, Michele Felletti, Julien Mortier, Eloisa Turco, Kristina Jonas

PLOS Genetics: published November 27, 2023 | https://doi.org/10.1371/journal.pgen.1010882

Electrical synapse structure requires distinct isoforms of a postsynaptic scaffold

Jennifer Carlisle Michel, Margaret M. B. Grivette, Amber T. Harshfield, Lisa Huynh, Ava P. Komons, Bradley Loomis, Kaitlan McKinnis, Brennen T. Miller, Ethan Q. Nguyen, Tiffany W. Huang, Sophia Lauf, Elias S. Michel, Mia E. Michel, Jane S. Kissinger, Audrey J. Marsh, William E. Crow, Lila E. Kaye, Abagael M. Lasseigne, Rachel M. Lukowicz-Bedford, Dylan R. Farnsworth, E. Anne Martin, Adam C. Miller

PLOS Genetics: published November 27, 2023 | https://doi.org/10.1371/journal.pgen.1011045

A dynamic population of prophase CENP-C is required for meiotic chromosome segregation

Jessica E. Fellmeth, Janet K. Jang, Manisha Persaud, Hannah Sturm, Neha Changela, Aashka Parikh, Kim S. McKim

PLOS Genetics: published November 29, 2023 | https://doi.org/10.1371/journal.pgen.1011066

Mutational impact of APOBEC3A and APOBEC3B in a human cell line and comparisons to breast cancer

Michael A. Carpenter, Nuri A. Temiz, Mahmoud A. Ibrahim, Matthew C. Jarvis, Margaret R. Brown, Prokopios P. Argyris, William L. Brown, Gabriel J. Starrett, Douglas Yee, Reuben S. Harris

PLOS Genetics: published November 30, 2023 | https://doi.org/10.1371/journal.pgen.1011043

Correction: Spatial regulation of Drosophila ovarian Follicle Stem Cell division rates and cell cycle transitions

David Melamed, Aaron Choi, Amy Reilein, Simon Tavaré, Daniel Kalderon

PLOS Genetics: published November 13, 2023 | https://doi.org/10.1371/journal.pgen.1011040

Related Articles

1. Spatial regulation of Drosophila ovarian Follicle Stem Cell division rates and cell cycle transitions

Correction: The circadian clock gene bmal1 is necessary for co-ordinated circatidal rhythms in the marine isopod Eurydice pulchra (Leach)

Lin Zhang, Edward W. Green, Simon G. Webster, Michael H. Hastings, David C. Wilcockson, Charalambos P. Kyriacou

PLOS Genetics: published November 15, 2023 | https://doi.org/10.1371/journal.pgen.1011047

Related Articles

1. The circadian clock gene bmal1 is necessary for co-ordinated circatidal rhythms in the marine isopod Eurydice pulchra (Leach)

Correction: It’s All in Your Mind: Determining Germ Cell Fate by Neuronal IRE-1 in C. elegans

Mor Levi-Ferber, Yehuda Salzberg, Modi Safra, Anat Haviv-Chesner, Hannes E. Bülow, Sivan Henis-Korenblit

PLOS Genetics: published November 30, 2023 | https://doi.org/10.1371/journal.pgen.1011061

Related Articles

1. It's All in Your Mind: Determining Germ Cell Fate by Neuronal IRE-1 in C. elegans

BRASS: Permutation methods for binary traits in genetic association studies with structured samples

Joelle Mbatchou, Mark Abney, Mary Sara McPeek

PLOS Genetics: published November 7, 2023 | https://doi.org/10.1371/journal.pgen.1011020

An allele-sharing, moment-based estimator of global, population-specific and population-pair F_ST under a general model of population structure

Jerome Goudet, Bruce S. Weir

PLOS Genetics: published November 27, 2023 | https://doi.org/10.1371/journal.pgen.1010871

Related Articles

1. Correction: An allele-sharing, moment-based estimator of global, population-specific and population-pair F_ST under a general model of population structure

Inferring multi-locus selection in admixed populations

Nicolas M. Ayala, Maximilian Genetti, Russell Corbett-Detig

PLOS Genetics: published November 28, 2023 | https://doi.org/10.1371/journal.pgen.1011062