ABCs of Insect Resistance to Bt

Bruce E. Tabashnik

PLOS Genetics: published November 19, 2015 | https://doi.org/10.1371/journal.pgen.1005646

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Ernst Rüdin and the State of Science

Michael Yudell

PLOS Genetics: published November 18, 2015 | https://doi.org/10.1371/journal.pgen.1005707

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Agricultural Genomics: Commercial Applications Bring Increased Basic Research Power

Jared E. Decker

PLOS Genetics: published November 5, 2015 | https://doi.org/10.1371/journal.pgen.1005621

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Genomics of Cancer and a New Era for Cancer Prevention

Paul Brennan, Christopher P. Wild

PLOS Genetics: published November 5, 2015 | https://doi.org/10.1371/journal.pgen.1005522

Pleiotropic Effects of Immune Responses Explain Variation in the Prevalence of Fibroproliferative Diseases

Shirley B. Russell, Joan C. Smith, Minjun Huang, Joel S. Trupin, Scott M. Williams

PLOS Genetics: published November 5, 2015 | https://doi.org/10.1371/journal.pgen.1005568

Variation in Rural African Gut Microbiota Is Strongly Correlated with Colonization by Entamoeba and Subsistence

Elise R. Morton, Joshua Lynch, Alain Froment, Sophie Lafosse, Evelyne Heyer, Molly Przeworski, Ran Blekhman, Laure Ségurel

PLOS Genetics: published November 30, 2015 | https://doi.org/10.1371/journal.pgen.1005658

Identifying Loci Contributing to Natural Variation in Xenobiotic Resistance in Drosophila

Michael A. Najarro, Jennifer L. Hackett, Brittny R. Smith, Chad A. Highfill, Elizabeth G. King, Anthony D. Long, Stuart J. Macdonald

PLOS Genetics: published November 30, 2015 | https://doi.org/10.1371/journal.pgen.1005663

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The QTL within the H2 Complex Involved in the Control of Tuberculosis Infection in Mice Is the Classical Class II H2-Ab1 Gene

Nadezhda Logunova, Maria Korotetskaya, Vladimir Polshakov, Alexander Apt

PLOS Genetics: published November 30, 2015 | https://doi.org/10.1371/journal.pgen.1005672

A Flexible, Efficient Binomial Mixed Model for Identifying Differential DNA Methylation in Bisulfite Sequencing Data

Amanda J. Lea, Jenny Tung, Xiang Zhou

PLOS Genetics: published November 24, 2015 | https://doi.org/10.1371/journal.pgen.1005650

The Multi-allelic Genetic Architecture of a Variance-Heterogeneity Locus for Molybdenum Concentration in Leaves Acts as a Source of Unexplained Additive Genetic Variance

Simon K. G. Forsberg, Matthew E. Andreatta, Xin-Yuan Huang, John Danku, David E. Salt, Örjan Carlborg

PLOS Genetics: published November 23, 2015 | https://doi.org/10.1371/journal.pgen.1005648

Competition between Heterochromatic Loci Allows the Abundance of the Silencing Protein, Sir4, to Regulate de novo Assembly of Heterochromatin

Michelle L. Larin, Katherine Harding, Elizabeth C. Williams, Noel Lianga, Carole Doré, Sophie Pilon, Éric Langis, Corey Yanofsky, Adam D. Rudner

PLOS Genetics: published November 20, 2015 | https://doi.org/10.1371/journal.pgen.1005425

Curly Encodes Dual Oxidase, Which Acts with Heme Peroxidase Curly Su to Shape the Adult Drosophila Wing

Thomas Ryan Hurd, Feng-Xia Liang, Ruth Lehmann

PLOS Genetics: published November 20, 2015 | https://doi.org/10.1371/journal.pgen.1005625

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Genome-Wide Association Study of Golden Retrievers Identifies Germ-Line Risk Factors Predisposing to Mast Cell Tumours

Maja L. Arendt, Malin Melin, Noriko Tonomura, Michele Koltookian, Celine Courtay-Cahen, Netty Flindall, Joyce Bass, Kim Boerkamp, Katherine Megquir, Lisa Youell, Sue Murphy, Colleen McCarthy, Cheryl London, Gerard R. Rutteman, Mike Starkey, Kerstin Lindblad-Toh

PLOS Genetics: published November 20, 2015 | https://doi.org/10.1371/journal.pgen.1005647

Conserved piRNA Expression from a Distinct Set of piRNA Cluster Loci in Eutherian Mammals

Gung-wei Chirn, Reazur Rahman, Yuliya A. Sytnikova, Jessica A. Matts, Mei Zeng, Daniel Gerlach, Michael Yu, Bonnie Berger, Mayumi Naramura, Benjamin T. Kile, Nelson C. Lau

PLOS Genetics: published November 20, 2015 | https://doi.org/10.1371/journal.pgen.1005652

A Cytosine Methytransferase Modulates the Cell Envelope Stress Response in the Cholera Pathogen

Michael C. Chao, Shijia Zhu, Satoshi Kimura, Brigid M. Davis, Eric E. Schadt, Gang Fang, Matthew K. Waldor

PLOS Genetics: published November 20, 2015 | https://doi.org/10.1371/journal.pgen.1005666

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A Tandem Duplicate of Anti-Müllerian Hormone with a Missense SNP on the Y Chromosome Is Essential for Male Sex Determination in Nile Tilapia, Oreochromis niloticus

Minghui Li, Yunlv Sun, Jiue Zhao, Hongjuan Shi, Sheng Zeng, Kai Ye, Dongneng Jiang, Linyan Zhou, Lina Sun, Wenjing Tao, Yoshitaka Nagahama, Thomas D. Kocher, Deshou Wang

PLOS Genetics: published November 20, 2015 | https://doi.org/10.1371/journal.pgen.1005678

The lncRNA RZE1 Controls Cryptococcal Morphological Transition

Nadia Chacko, Youbao Zhao, Ence Yang, Linqi Wang, James J. Cai, Xiaorong Lin

PLOS Genetics: published November 20, 2015 | https://doi.org/10.1371/journal.pgen.1005692

Insect Resistance to Bacillus thuringiensis Toxin Cry2Ab Is Conferred by Mutations in an ABC Transporter Subfamily A Protein

Wee Tek Tay, Rod J. Mahon, David G. Heckel, Thomas K. Walsh, Sharon Downes, William J. James, Sui-Fai Lee, Annette Reineke, Adam K. Williams, Karl H. J. Gordon

PLOS Genetics: published November 19, 2015 | https://doi.org/10.1371/journal.pgen.1005534

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Epigenetic Control of Salmonella enterica O-Antigen Chain Length: A Tradeoff between Virulence and Bacteriophage Resistance

Ignacio Cota, María Antonia Sánchez-Romero, Sara B. Hernández, M. Graciela Pucciarelli, Francisco García-del Portillo, Josep Casadesús

PLOS Genetics: published November 19, 2015 | https://doi.org/10.1371/journal.pgen.1005667

The Fanconi Anemia Pathway Protects Genome Integrity from R-loops

María L. García-Rubio, Carmen Pérez-Calero, Sonia I. Barroso, Emanuela Tumini, Emilia Herrera-Moyano, Iván V. Rosado, Andrés Aguilera

PLOS Genetics: published November 19, 2015 | https://doi.org/10.1371/journal.pgen.1005674

Sae2 Function at DNA Double-Strand Breaks Is Bypassed by Dampening Tel1 or Rad53 Activity

Elisa Gobbini, Matteo Villa, Marco Gnugnoli, Luca Menin, Michela Clerici, Maria Pia Longhese

PLOS Genetics: published November 19, 2015 | https://doi.org/10.1371/journal.pgen.1005685

Ectodysplasin/NF-κB Promotes Mammary Cell Fate via Wnt/β-catenin Pathway

Maria Voutilainen, Päivi H. Lindfors, Ewelina Trela, Darielle Lönnblad, Vera Shirokova, Teresa Elo, Elisa Rysti, Ruth Schmidt-Ullrich, Pascal Schneider, Marja L. Mikkola

PLOS Genetics: published November 18, 2015 | https://doi.org/10.1371/journal.pgen.1005676

KRN4 Controls Quantitative Variation in Maize Kernel Row Number

Lei Liu, Yanfang Du, Xiaomeng Shen, Manfei Li, Wei Sun, Juan Huang, Zhijie Liu, Yongsheng Tao, Yonglian Zheng, Jianbing Yan, Zuxin Zhang

PLOS Genetics: published November 17, 2015 | https://doi.org/10.1371/journal.pgen.1005670

Convergent Evolution During Local Adaptation to Patchy Landscapes

Peter L. Ralph, Graham Coop

PLOS Genetics: published November 16, 2015 | https://doi.org/10.1371/journal.pgen.1005630

Calibrating the Human Mutation Rate via Ancestral Recombination Density in Diploid Genomes

Mark Lipson, Po-Ru Loh, Sriram Sankararaman, Nick Patterson, Bonnie Berger, David Reich

PLOS Genetics: published November 12, 2015 | https://doi.org/10.1371/journal.pgen.1005550

Enhancer Runaway and the Evolution of Diploid Gene Expression

Frédéric Fyon, Aurélie Cailleau, Thomas Lenormand

PLOS Genetics: published November 12, 2015 | https://doi.org/10.1371/journal.pgen.1005665

The vgll3 Locus Controls Age at Maturity in Wild and Domesticated Atlantic Salmon (Salmo salar L.) Males

Fernando Ayllon, Erik Kjærner-Semb, Tomasz Furmanek, Vidar Wennevik, Monica F. Solberg, Geir Dahle, Geir Lasse Taranger, Kevin A. Glover, Markus Sällman Almén, Carl J Rubin, Rolf B. Edvardsen, Anna Wargelius

PLOS Genetics: published November 9, 2015 | https://doi.org/10.1371/journal.pgen.1005628

Ernst Rüdin’s Unpublished 1922-1925 Study “Inheritance of Manic-Depressive Insanity”: Genetic Research Findings Subordinated to Eugenic Ideology

Gundula Kösters, Holger Steinberg, Kenneth Clifford Kirkby, Hubertus Himmerich

PLOS Genetics: published November 6, 2015 | https://doi.org/10.1371/journal.pgen.1005524

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Adaptation to High Ethanol Reveals Complex Evolutionary Pathways

Karin Voordeckers, Jacek Kominek, Anupam Das, Adriana Espinosa-Cantú, Dries De Maeyer, Ahmed Arslan, Michiel Van Pee, Elisa van der Zande, Wim Meert, Yudi Yang, Bo Zhu, Kathleen Marchal, Alexander DeLuna, Vera Van Noort, Rob Jelier, Kevin J. Verstrepen

PLOS Genetics: published November 6, 2015 | https://doi.org/10.1371/journal.pgen.1005635

Dynamics of Transcription Factor Binding Site Evolution

Murat Tuğrul, Tiago Paixão, Nicholas H. Barton, Gašper Tkačik

PLOS Genetics: published November 6, 2015 | https://doi.org/10.1371/journal.pgen.1005639

UFBP1, a Key Component of the Ufm1 Conjugation System, Is Essential for Ufmylation-Mediated Regulation of Erythroid Development

Yafei Cai, Wenhu Pi, Satish Sivaprakasam, Xiaobin Zhu, Mingsheng Zhang, Jijun Chen, Levi Makala, Chunwan Lu, Jianchu Wu, Yong Teng, Betty Pace, Dorothy Tuan, Nagendra Singh, Honglin Li

PLOS Genetics: published November 6, 2015 | https://doi.org/10.1371/journal.pgen.1005643

Absence of Maternal Methylation in Biparental Hydatidiform Moles from Women with NLRP7 Maternal-Effect Mutations Reveals Widespread Placenta-Specific Imprinting

Marta Sanchez-Delgado, Alejandro Martin-Trujillo, Chiharu Tayama, Enrique Vidal, Manel Esteller, Isabel Iglesias-Platas, Nandita Deo, Olivia Barney, Ken Maclean, Kenichiro Hata, Kazuhiko Nakabayashi, Rosemary Fisher, David Monk

PLOS Genetics: published November 6, 2015 | https://doi.org/10.1371/journal.pgen.1005644

DNA Repair Cofactors ATMIN and NBS1 Are Required to Suppress T Cell Activation

Jana Prochazkova, Shinya Sakaguchi, Michel Owusu, Abdelghani Mazouzi, Marc Wiedner, Georgia Velimezi, Martin Moder, Gleb Turchinovich, Anastasiya Hladik, Elisabeth Gurnhofer, Adrian Hayday, Axel Behrens, Sylvia Knapp, Lukas Kenner, Wilfried Ellmeier, Joanna I. Loizou

PLOS Genetics: published November 6, 2015 | https://doi.org/10.1371/journal.pgen.1005645

Connecting Replication and Repair: YoaA, a Helicase-Related Protein, Promotes Azidothymidine Tolerance through Association with Chi, an Accessory Clamp Loader Protein

Laura T. Brown, Vincent A. Sutera Jr., Shen Zhou, Christopher S. Weitzel, Yisha Cheng, Susan T. Lovett

PLOS Genetics: published November 6, 2015 | https://doi.org/10.1371/journal.pgen.1005651

Drosophila Nipped-B Mutants Model Cornelia de Lange Syndrome in Growth and Behavior

Yaning Wu, Maria Gause, Dongbin Xu, Ziva Misulovin, Cheri A. Schaaf, Ramya C. Mosarla, Elizabeth Mannino, Megan Shannon, Emily Jones, Mi Shi, Wen-Feng Chen, Olivia L. Katz, Amita Sehgal, Thomas A. Jongens, Ian D. Krantz, Dale Dorsett

PLOS Genetics: published November 6, 2015 | https://doi.org/10.1371/journal.pgen.1005655

QTL Mapping of Sex Determination Loci Supports an Ancient Pathway in Ants and Honey Bees

Misato O. Miyakawa, Alexander S. Mikheyev

PLOS Genetics: published November 6, 2015 | https://doi.org/10.1371/journal.pgen.1005656

Genetic Interactions Implicating Postreplicative Repair in Okazaki Fragment Processing

Jordan R. Becker, Carles Pons, Hai Dang Nguyen, Michael Costanzo, Charles Boone, Chad L. Myers, Anja-Katrin Bielinsky

PLOS Genetics: published November 6, 2015 | https://doi.org/10.1371/journal.pgen.1005659

Cattle Sex-Specific Recombination and Genetic Control from a Large Pedigree Analysis

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PLOS Genetics: published November 5, 2015 | https://doi.org/10.1371/journal.pgen.1005387

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Metabolomic Quantitative Trait Loci (mQTL) Mapping Implicates the Ubiquitin Proteasome System in Cardiovascular Disease Pathogenesis

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PLOS Genetics: published November 5, 2015 | https://doi.org/10.1371/journal.pgen.1005553

A Hereditary Enteropathy Caused by Mutations in the SLCO2A1 Gene, Encoding a Prostaglandin Transporter

Junji Umeno, Tadakazu Hisamatsu, Motohiro Esaki, Atsushi Hirano, Naoya Kubokura, Kouichi Asano, Shuji Kochi, Shunichi Yanai, Yuta Fuyuno, Katsuyoshi Shimamura, Naoki Hosoe, Haruhiko Ogata, Takashi Watanabe, Kunihiko Aoyagi, Hidehisa Ooi, Kenji Watanabe, Shigeyoshi Yasukawa, Fumihito Hirai, Toshiyuki Matsui, Mitsuo Iida, Tsuneyoshi Yao, Toshifumi Hibi, Kenjiro Kosaki, Takanori Kanai, Takanari Kitazono, Takayuki Matsumoto

PLOS Genetics: published November 5, 2015 | https://doi.org/10.1371/journal.pgen.1005581

Genus-Wide Comparative Genomics of Malassezia Delineates Its Phylogeny, Physiology, and Niche Adaptation on Human Skin

Guangxi Wu, He Zhao, Chenhao Li, Menaka Priyadarsani Rajapakse, Wing Cheong Wong, Jun Xu, Charles W. Saunders, Nancy L. Reeder, Raymond A. Reilman, Annika Scheynius, Sheng Sun, Blake Robert Billmyre, Wenjun Li, Anna Floyd Averette, Piotr Mieczkowski, Joseph Heitman, Bart Theelen, Markus S. Schröder, Paola Florez De Sessions, Geraldine Butler, Sebastian Maurer-Stroh, Teun Boekhout, Niranjan Nagarajan, Thomas L. Dawson Jr.

PLOS Genetics: published November 5, 2015 | https://doi.org/10.1371/journal.pgen.1005614

Conserved Genetic Interactions between Ciliopathy Complexes Cooperatively Support Ciliogenesis and Ciliary Signaling

Laura E. Yee, Francesc R. Garcia-Gonzalo, Rachel V. Bowie, Chunmei Li, Julie K. Kennedy, Kaveh Ashrafi, Oliver E. Blacque, Michel R. Leroux, Jeremy F. Reiter

PLOS Genetics: published November 5, 2015 | https://doi.org/10.1371/journal.pgen.1005627

Mosaic and Intronic Mutations in TSC1/TSC2 Explain the Majority of TSC Patients with No Mutation Identified by Conventional Testing

Magdalena E. Tyburczy, Kira A. Dies, Jennifer Glass, Susana Camposano, Yvonne Chekaluk, Aaron R. Thorner, Ling Lin, Darcy Krueger, David N. Franz, Elizabeth A. Thiele, Mustafa Sahin, David J. Kwiatkowski

PLOS Genetics: published November 5, 2015 | https://doi.org/10.1371/journal.pgen.1005637

Spindle-F Is the Central Mediator of Ik2 Kinase-Dependent Dendrite Pruning in Drosophila Sensory Neurons

Tzu Lin, Po-Yuan Pan, Yu-Ting Lai, Kai-Wen Chiang, Hsin-Lun Hsieh, Yi-Ping Wu, Jian-Ming Ke, Myong-Chol Lee, Shih-Sian Liao, Hsueh-Tzu Shih, Chiou-Yang Tang, Shi-Bing Yang, Hsu-Chen Cheng, June-Tai Wu, Yuh-Nung Jan, Hsiu-Hsiang Lee

PLOS Genetics: published November 5, 2015 | https://doi.org/10.1371/journal.pgen.1005642

Members of the RAD52 Epistasis Group Contribute to Mitochondrial Homologous Recombination and Double-Strand Break Repair in Saccharomyces cerevisiae

Alexis Stein, Lidza Kalifa, Elaine A. Sia

PLOS Genetics: published November 5, 2015 | https://doi.org/10.1371/journal.pgen.1005664

Anaplastic Lymphoma Kinase Acts in the Drosophila Mushroom Body to Negatively Regulate Sleep

Lei Bai, Amita Sehgal

PLOS Genetics: published November 4, 2015 | https://doi.org/10.1371/journal.pgen.1005611

Leaderless Transcripts and Small Proteins Are Common Features of the Mycobacterial Translational Landscape

Scarlet S. Shell, Jing Wang, Pascal Lapierre, Mushtaq Mir, Michael R. Chase, Margaret M. Pyle, Richa Gawande, Rushdy Ahmad, David A. Sarracino, Thomas R. Ioerger, Sarah M. Fortune, Keith M. Derbyshire, Joseph T. Wade, Todd A. Gray

PLOS Genetics: published November 4, 2015 | https://doi.org/10.1371/journal.pgen.1005641

Exocyst-Dependent Membrane Addition Is Required for Anaphase Cell Elongation and Cytokinesis in Drosophila

Maria Grazia Giansanti, Timothy E. Vanderleest, Cayla E. Jewett, Stefano Sechi, Anna Frappaolo, Lacramioara Fabian, Carmen C. Robinett, Julie A. Brill, Dinah Loerke, Margaret T. Fuller, J. Todd Blankenship

PLOS Genetics: published November 3, 2015 | https://doi.org/10.1371/journal.pgen.1005632

Tissue-Specific Effects of Reduced β-catenin Expression on Adenomatous Polyposis Coli Mutation-Instigated Tumorigenesis in Mouse Colon and Ovarian Epithelium

Ying Feng, Naoya Sakamoto, Rong Wu, Jie-yu Liu, Alexandra Wiese, Maranne E. Green, Megan Green, Aytekin Akyol, Badal C. Roy, Yali Zhai, Kathleen R. Cho, Eric R. Fearon

PLOS Genetics: published November 3, 2015 | https://doi.org/10.1371/journal.pgen.1005638

Mapping of Craniofacial Traits in Outbred Mice Identifies Major Developmental Genes Involved in Shape Determination

Luisa F. Pallares, Peter Carbonetto, Shyam Gopalakrishnan, Clarissa C. Parker, Cheryl L. Ackert-Bicknell, Abraham A. Palmer, Diethard Tautz

PLOS Genetics: published November 2, 2015 | https://doi.org/10.1371/journal.pgen.1005607